Gene description for SIAH2
Gene name	siah E3 ubiquitin protein ligase 2
Gene symbol	SIAH2
Other names/aliases	hSiah2
Species	Homo sapiens
Database cross references - SIAH2
ExoCarta	ExoCarta_6478
Vesiclepedia	VP_6478
Entrez Gene	6478
HGNC	10858
MIM	602213
UniProt	O43255
SIAH2 identified in exosomes derived from the following tissue/cell type
Hepatocytes	26054723

Gene ontology annotations for SIAH2

Molecular Function     ubiquitin conjugating enzyme binding GO:0031624 IEA     protein binding GO:0005515 IPI     transcription corepressor activity GO:0003714 TAS     ligase activity GO:0016874 IEA     ubiquitin-protein transferase activity GO:0004842 IEA     zinc ion binding GO:0008270 IEA Biological Process     protein ubiquitination GO:0016567 IEA     negative regulation of extrinsic apoptotic signaling pathway GO:2001237 IMP     negative regulation of apoptotic process GO:0043066 IMP     axon guidance GO:0007411 TAS     negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043154 IMP     small GTPase mediated signal transduction GO:0007264 TAS     negative regulation of canonical Wnt signaling pathway GO:0090090 IGI     cellular protein catabolic process GO:0044257 IGI     ubiquitin-dependent protein catabolic process GO:0006511 IEA     regulation of protein ubiquitination GO:0031396 IEA     negative regulation of nucleic acid-templated transcription GO:1903507 TAS     cell cycle GO:0007049 IEA Subcellular Localization     neuron projection GO:0043005 IEA     nucleoplasm GO:0005654 IDA     cytosol GO:0005829 TAS     intracellular membrane-bounded organelle GO:0043231 IDA     early endosome GO:0005769 IEA     cytoplasm GO:0005737 TAS     neuronal cell body GO:0043025 IEA