Gene description for VAV1
Gene name	vav 1 guanine nucleotide exchange factor
Gene symbol	VAV1
Other names/aliases	VAV
Species	Homo sapiens
Database cross references - VAV1
ExoCarta	ExoCarta_7409
Entrez Gene	7409
HGNC	12657
MIM	164875
UniProt	P15498
VAV1 identified in exosomes derived from the following tissue/cell type
Platelets	25332113
Platelets	25332113
Platelets	25332113
Thymus	23844026

Gene ontology annotations for VAV1

Molecular Function     protein binding GO:0005515 IPI     metal ion binding GO:0046872 IEA     sequence-specific DNA binding transcription factor activity GO:0003700 TAS     guanyl-nucleotide exchange factor activity GO:0005085 TAS     Rac guanyl-nucleotide exchange factor activity GO:0030676 IEA Biological Process     fibroblast growth factor receptor signaling pathway GO:0008543 TAS     reactive oxygen species metabolic process GO:0072593 IEA     G-protein coupled receptor signaling pathway GO:0007186 IEA     Fc-gamma receptor signaling pathway involved in phagocytosis GO:0038096 TAS     small GTPase mediated signal transduction GO:0007264 TAS     platelet activation GO:0030168 TAS     integrin-mediated signaling pathway GO:0007229 IEA     vascular endothelial growth factor receptor signaling pathway GO:0048010 TAS     Fc-epsilon receptor signaling pathway GO:0038095 TAS     innate immune response GO:0045087 TAS     blood coagulation GO:0007596 TAS     positive regulation of apoptotic process GO:0043065 TAS     phosphatidylinositol-mediated signaling GO:0048015 TAS     epidermal growth factor receptor signaling pathway GO:0007173 TAS     positive regulation of GTPase activity GO:0043547 TAS     apoptotic signaling pathway GO:0097190 TAS     T cell activation GO:0042110 IEA     neutrophil chemotaxis GO:0030593 IEA     regulation of small GTPase mediated signal transduction GO:0051056 TAS     regulation of transcription, DNA-templated GO:0006355 TAS     T cell costimulation GO:0031295 TAS     neurotrophin TRK receptor signaling pathway GO:0048011 TAS Subcellular Localization     cytosol GO:0005829 TAS     cell-cell junction GO:0005911 IEA     plasma membrane GO:0005886 TAS