Gene description for DOCK2
Gene name	dedicator of cytokinesis 2
Gene symbol	DOCK2
Other names/aliases	-
Species	Homo sapiens
Database cross references - DOCK2
ExoCarta	ExoCarta_1794
Entrez Gene	1794
HGNC	2988
MIM	603122
UniProt	Q92608
DOCK2 identified in exosomes derived from the following tissue/cell type
B cells	20458337
B cells	20458337
Neuroblastoma cells	25944692
Thymus	23844026

Gene ontology annotations for DOCK2

Molecular Function     T cell receptor binding GO:0042608 IDA     protein binding GO:0005515 IPI     Rac guanyl-nucleotide exchange factor activity GO:0030676 IDA Biological Process     negative thymic T cell selection GO:0045060 IEA     alpha-beta T cell proliferation GO:0046633 IEA     positive thymic T cell selection GO:0045059 IEA     viral process GO:0016032 TAS     regulation of defense response to virus by virus GO:0050690 TAS     membrane raft polarization GO:0001766 IEA     actin cytoskeleton organization GO:0030036 TAS     positive regulation of GTPase activity GO:0043547 IEA     immunological synapse formation GO:0001771 IEA     chemotaxis GO:0006935 IEA     establishment of T cell polarity GO:0001768 IEA     positive regulation of phagocytosis GO:0050766 ISS     myeloid dendritic cell activation involved in immune response GO:0002277 ISS     small GTPase mediated signal transduction GO:0007264 IEA     macropinocytosis GO:0044351 ISS Subcellular Localization     membrane GO:0016020 IDA     cytosol GO:0005829 TAS     cytoskeleton GO:0005856 IEA     endomembrane system GO:0012505 IEA     extracellular exosome GO:0070062 IDA