Gene description for CCNDBP1
Gene name cyclin D-type binding-protein 1
Gene symbol CCNDBP1
Other names/aliases DIP1
GCIP
HHM
Species Homo sapiens
 Database cross references - CCNDBP1
ExoCarta ExoCarta_23582
Entrez Gene 23582
HGNC 1587
MIM 607089
UniProt O95273  
 CCNDBP1 identified in exosomes derived from the following tissue/cell type
Prostate cancer cells 25844599    
 Gene ontology annotations for CCNDBP1
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    cell cycle GO:0007049 IEA
    regulation of cell cycle GO:0051726 IEA
Subcellular Localization
    cytoplasm GO:0005737 IEA
    nucleoplasm GO:0005654 IDA
    nucleus GO:0005634 IDA
 Experiment description of studies that identified CCNDBP1 in exosomes
1
Experiment ID 274
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|RAB5A
EV Cytosolic markers
CD9|CD82|CD63|CD81
EV Membrane markers
AIF
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T.
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel resistant
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.18 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Flow cytometry
Western blotting
 Protein-protein interactions for CCNDBP1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CCND1 595
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
2 GRAP2 9402
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
3 ZNF334  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which CCNDBP1 is involved
No pathways found





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