Gene description for GRAP2
Gene name
GRB2-related adaptor protein 2
Gene symbol
GRAP2
Other names/aliases
GADS GRAP-2 GRB2L GRBLG GRID GRPL GrbX Grf40 Mona P38
Species
Homo sapiens
Database cross references - GRAP2
ExoCarta
ExoCarta_9402
Entrez Gene
9402
HGNC
4563
MIM
604518
UniProt
O75791
GRAP2 identified in exosomes derived from the following tissue/cell type
Platelets
25332113
Platelets
25332113
Platelets
25332113
Gene ontology annotations for GRAP2
Experiment description of studies that identified GRAP2 in exosomes
1
Experiment ID
231
ISEV standards
✘
EV Biophysical techniques
✔
Alix
EV Cytosolic markers
✔
CD63|CD9
EV Membrane markers
✘
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25332113
Organism
Homo sapiens
Experiment description
Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors
Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G.
Journal name
Transfusion
Publication year
2015
Sample
Platelets
Sample name
PL-Exs - Rep 1
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Optiprep density gradient
Flotation density
1.12-1.15 g/mL
Molecules identified in the study
Protein Lipids
Methods used in the study
Western blotting Mass spectrometry
2
Experiment ID
232
ISEV standards
✘
EV Biophysical techniques
✘
EV Cytosolic markers
✘
EV Membrane markers
✘
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25332113
Organism
Homo sapiens
Experiment description
Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors
Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G.
Journal name
Transfusion
Publication year
2015
Sample
Platelets
Sample name
PL-Exs - Rep 2
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Optiprep density gradient
Flotation density
1.12-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
3
Experiment ID
233
ISEV standards
✘
EV Biophysical techniques
✘
EV Cytosolic markers
✘
EV Membrane markers
✘
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25332113
Organism
Homo sapiens
Experiment description
Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors
Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G.
Journal name
Transfusion
Publication year
2015
Sample
Platelets
Sample name
PL-Exs - Rep 3
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Optiprep density gradient
Flotation density
1.12-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
Protein-protein interactions for GRAP2
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
CD28
Affinity Capture-Western
Homo sapiens
Two-hybrid
Homo sapiens
Reconstituted Complex
Homo sapiens
2
LAT
27040
Invivo
Homo sapiens
Affinity Capture-MS
Homo sapiens
3
CCNDBP1
23582
Two-hybrid
Homo sapiens
Affinity Capture-MS
Homo sapiens
Reconstituted Complex
Homo sapiens
Affinity Capture-Western
Homo sapiens
4
GAB3
Invitro
Homo sapiens
5
SHC1
6464
Affinity Capture-MS
Homo sapiens
6
RBPMS
Two-hybrid
Homo sapiens
7
YWHAE
7531
Two-hybrid
Homo sapiens
8
GFAP
2670
Two-hybrid
Homo sapiens
9
FASLG
356
Invivo
Homo sapiens
Invitro
Homo sapiens
10
GAB2
9846
Invitro
Homo sapiens
11
HNRNPK
3190
Two-hybrid
Homo sapiens
12
GAB1
Two-hybrid
Homo sapiens
13
KRTAP4-12
Two-hybrid
Homo sapiens
14
LCP2
3937
Two-hybrid
Homo sapiens
Affinity Capture-MS
Homo sapiens
Invivo
Homo sapiens
Invivo
Homo sapiens
Invitro
Homo sapiens
Invitro
Homo sapiens
Reconstituted Complex
Homo sapiens
15
ZBTB7B
Two-hybrid
Homo sapiens
16
SOS2
6655
Reconstituted Complex
Homo sapiens
17
GNB2L1
10399
Affinity Capture-MS
Homo sapiens
Reconstituted Complex
Homo sapiens
18
KHDRBS1
10657
Reconstituted Complex
Homo sapiens
19
STAMBP
10617
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
Affinity Capture-MS
Homo sapiens
20
FLJ11588
Two-hybrid
Homo sapiens
21
CSF1R
Reconstituted Complex
Homo sapiens
22
MAP4K1
Affinity Capture-Western
Homo sapiens
Reconstituted Complex
Homo sapiens
Two-hybrid
Homo sapiens
Phenotypic Enhancement
Homo sapiens
View the network
image/svg+xml
Pathways in which GRAP2 is involved