Gene description for LAT
Gene name	linker for activation of T cells
Gene symbol	LAT
Other names/aliases	LAT1 pp36
Species	Homo sapiens
Database cross references - LAT
ExoCarta	ExoCarta_27040
Entrez Gene	27040
HGNC	18874
MIM	602354
UniProt	O43561
LAT identified in exosomes derived from the following tissue/cell type
Platelets	25332113
Platelets	25332113
Platelets	25332113
Thymus	23844026

Gene ontology annotations for LAT

Molecular Function     SH3/SH2 adaptor activity GO:0005070 IDA     protein kinase binding GO:0019901 IPI     protein binding GO:0005515 IPI Biological Process     Ras protein signal transduction GO:0007265 IMP     T cell receptor signaling pathway GO:0050852 TAS     calcium-mediated signaling GO:0019722 IMP     positive regulation of signal transduction GO:0009967 IDA     Fc-epsilon receptor signaling pathway GO:0038095 TAS     regulation of T cell activation GO:0050863 IMP     positive regulation of protein kinase activity GO:0045860 IEP     platelet activation GO:0030168 TAS     blood coagulation GO:0007596 TAS     innate immune response GO:0045087 TAS     gene expression GO:0010467 IEA     intracellular signal transduction GO:0035556 IDA     mast cell degranulation GO:0043303 IEA     lymphocyte homeostasis GO:0002260 IEA     inflammatory response GO:0006954 IEA     T cell activation GO:0042110 TAS     immune response GO:0006955 IDA     integrin-mediated signaling pathway GO:0007229 IDA Subcellular Localization     mast cell granule GO:0042629 IEA     plasma membrane GO:0005886 TAS     cell-cell junction GO:0005911 IEA     immunological synapse GO:0001772 IDA     membrane raft GO:0045121 TAS     integral component of membrane GO:0016021 IDA     COP9 signalosome GO:0008180 ISS