Gene description for SERINC2
Gene name serine incorporator 2
Gene symbol SERINC2
Other names/aliases FKSG84
PRO0899
TDE2
TDE2L
Species Homo sapiens
 Database cross references - SERINC2
ExoCarta ExoCarta_347735
Entrez Gene 347735
HGNC 23231
MIM 614549
UniProt Q96SA4  
 SERINC2 identified in exosomes derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for SERINC2
Molecular Function
    L-serine transmembrane transporter activity GO:0015194 IBA
Biological Process
    positive regulation of transferase activity GO:0051347 IEA
    phosphatidylserine metabolic process GO:0006658 IEA
    sphingolipid metabolic process GO:0006665 IEA
    L-serine transport GO:0015825 IBA
Subcellular Localization
    integral component of membrane GO:0016021 IBA
    extracellular exosome GO:0070062 IDA
 Experiment description of studies that identified SERINC2 in exosomes
1
Experiment ID 63
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
AQP2
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for SERINC2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which SERINC2 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here