Gene description for GPR89B
Gene name G protein-coupled receptor 89B
Gene symbol GPR89B
Other names/aliases GPHR
GPR89
GPR89C
SH120
UNQ192
Species Homo sapiens
 Database cross references - GPR89B
ExoCarta ExoCarta_51463
Vesiclepedia VP_51463
Entrez Gene 51463
HGNC 13840
MIM 612806
UniProt P0CG08   B7ZAQ6  
 GPR89B identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for GPR89B
Molecular Function
    protein binding GO:0005515 IPI
    voltage-gated monoatomic anion channel activity GO:0008308 IBA
Biological Process
    protein transport GO:0015031 IEA
    T cell differentiation GO:0030217 ISS
    intracellular pH reduction GO:0051452 IBA
    monoatomic anion transmembrane transport GO:0098656 IEA
Subcellular Localization
    Golgi membrane GO:0000139 IEA
    Golgi cisterna membrane GO:0032580 IBA
    monoatomic ion channel complex GO:0034702 IEA
 Experiment description of studies that identified GPR89B in exosomes
1
Experiment ID 489
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for GPR89B
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 GABRE  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
2 FNDC4 64838
Affinity Capture-MS Homo sapiens
3 APLNR  
Affinity Capture-MS Homo sapiens
4 MAS1  
Affinity Capture-MS Homo sapiens
5 TXNDC15  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 LPAR6  
Affinity Capture-MS Homo sapiens
7 CCRL2  
Affinity Capture-MS Homo sapiens
8 NR3C1 2908
Proximity Label-MS Homo sapiens
9 ST3GAL1 6482
Affinity Capture-MS Homo sapiens
10 EGFR 1956
Negative Genetic Homo sapiens
11 DNAJC25 548645
Proximity Label-MS Homo sapiens
12 SERINC1 57515
Affinity Capture-MS Homo sapiens
13 SERINC2 347735
Affinity Capture-MS Homo sapiens
14 KIAA1429 25962
Affinity Capture-MS Homo sapiens
15 PLD3 23646
Affinity Capture-MS Homo sapiens
16 FAM134C 162427
Affinity Capture-MS Homo sapiens
17 RPA3 6119
Proximity Label-MS Homo sapiens
18 GDPD5 81544
Affinity Capture-MS Homo sapiens
19 P2RY1  
Affinity Capture-MS Homo sapiens
20 SLC4A8 9498
Affinity Capture-MS Homo sapiens
21 DNAJC1 64215
Proximity Label-MS Homo sapiens
22 TMEM63A 9725
Affinity Capture-MS Homo sapiens
23 B4GALT3 8703
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
24 DNAJC16  
Proximity Label-MS Homo sapiens
25 PIGS 94005
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which GPR89B is involved
No pathways found





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