Gene description for SLC4A8
Gene name	solute carrier family 4, sodium bicarbonate cotransporter, member 8
Gene symbol	SLC4A8
Other names/aliases	NBC3 NDCBE
Species	Homo sapiens
Database cross references - SLC4A8
ExoCarta	ExoCarta_9498
Vesiclepedia	VP_9498
Entrez Gene	9498
HGNC	11034
MIM	605024
UniProt	Q2Y0W8
SLC4A8 identified in exosomes derived from the following tissue/cell type
Neuroblastoma cells	25944692

Gene ontology annotations for SLC4A8

Molecular Function     solute:inorganic anion antiporter activity GO:0005452 TAS     zinc ion binding GO:0008270 IDA     sodium:bicarbonate symporter activity GO:0008510 IBA     sodium:bicarbonate symporter activity GO:0008510 IDA     sodium ion transmembrane transporter activity GO:0015081 IDA     bicarbonate transmembrane transporter activity GO:0015106 IDA     chloride transmembrane transporter activity GO:0015108 IDA     identical protein binding GO:0042802 IDA     identical protein binding GO:0042802 IEA     sodium,bicarbonate:chloride antiporter activity GO:0140892 IDA     sodium,bicarbonate:chloride antiporter activity GO:0140892 IEA Biological Process     bicarbonate transport GO:0015701 IBA     bicarbonate transport GO:0015701 IDA     bicarbonate transport GO:0015701 TAS     sodium ion transmembrane transport GO:0035725 IDA     sodium ion transmembrane transport GO:0035725 IEA     regulation of membrane potential GO:0042391 IDA     modulation of chemical synaptic transmission GO:0050804 ISS     regulation of intracellular pH GO:0051453 IBA     regulation of intracellular pH GO:0051453 IDA     regulation of intracellular pH GO:0051453 ISS     transmembrane transport GO:0055085 IBA     basolateral protein secretion GO:0110010 IEA     transport across blood-brain barrier GO:0150104 NAS     chloride transmembrane transport GO:1902476 IDA     positive regulation of synaptic vesicle exocytosis GO:2000302 ISS Subcellular Localization     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 IDA     plasma membrane GO:0005886 ISS     plasma membrane GO:0005886 TAS     synaptic vesicle GO:0008021 ISS     membrane GO:0016020 ISS     basolateral plasma membrane GO:0016323 IEA     apical plasma membrane GO:0016324 IEA     dendrite GO:0030425 IDA     synaptic vesicle membrane GO:0030672 IEA     asymmetric synapse GO:0032279 ISS     symmetric synapse GO:0032280 ISS     neuronal cell body membrane GO:0032809 ISS     presynaptic membrane GO:0042734 ISS     neuron projection GO:0043005 ISS     terminal bouton GO:0043195 ISS     axon terminus GO:0043679 ISS     glial cell projection GO:0097386 ISS     hippocampal mossy fiber GO:0097457 ISS     presynapse GO:0098793 ISS     glutamatergic synapse GO:0098978 ISS