Experiment description of studies that identified C1orf43 in exosomes

1 Experiment ID 234 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N Journal name Carcinogenesis Publication year 2015 Sample Hepatocellular carcinoma cells Sample name HKCI-C3 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RT-PCR RNA Sequencing

2 Experiment ID 236 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N Journal name Carcinogenesis Publication year 2015 Sample Hepatocellular carcinoma cells Sample name MHCC97L Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RT-PCR RNA Sequencing

Protein-protein interactions for C1orf43

Protein Interactor ExoCarta ID Identification method PubMed Species 1 NKAIN1   Affinity Capture-MS Homo sapiens 2 HFE   Affinity Capture-MS Homo sapiens 3 PANX1 24145 Proximity Label-MS Homo sapiens 4 SLC25A31 83447 Affinity Capture-MS Homo sapiens 5 KCNS3 3790 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 6 PXMP2   Proximity Label-MS Homo sapiens 7 SNX27 81609 Affinity Capture-MS Homo sapiens 8 FASN 2194 Negative Genetic Homo sapiens 9 CNGA4   Affinity Capture-MS Homo sapiens 10 TPM2 7169 Affinity Capture-MS Homo sapiens 11 PCDHB7   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 12 ADCY9 115 Affinity Capture-MS Homo sapiens 13 CHRNA4   Affinity Capture-MS Homo sapiens 14 TTYH1   Affinity Capture-MS Homo sapiens 15 OR10H2   Affinity Capture-MS Homo sapiens 16 SIDT2 51092 Affinity Capture-MS Homo sapiens 17 PIGH   Affinity Capture-MS Homo sapiens 18 SLC39A4 55630 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 19 NRSN1   Affinity Capture-MS Homo sapiens 20 PDZD8 118987 Affinity Capture-MS Homo sapiens 21 ZDHHC12   Affinity Capture-MS Homo sapiens 22 PCDHAC1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 23 PTCH2   Affinity Capture-MS Homo sapiens 24 FAS 355 Proximity Label-MS Homo sapiens 25 PCDHGA4   Affinity Capture-MS Homo sapiens 26 IL17RA 23765 Affinity Capture-MS Homo sapiens 27 SLC39A8 64116 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 28 ADCY3 109 Affinity Capture-MS Homo sapiens 29 KIAA1109 84162 Affinity Capture-MS Homo sapiens 30 TMEM9B 56674 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 31 EMD 2010 Proximity Label-MS Homo sapiens 32 DNAJC25 548645 Proximity Label-MS Homo sapiens 33 PCDHA3   Affinity Capture-MS Homo sapiens 34 ADCY8   Affinity Capture-MS Homo sapiens 35 TRPV3   Affinity Capture-MS Homo sapiens 36 CXCR4 7852 Affinity Capture-MS Homo sapiens 37 STX4 6810 Proximity Label-MS Homo sapiens 38 SCAP   Affinity Capture-MS Homo sapiens 39 NXF1 10482 Affinity Capture-RNA Homo sapiens 40 PCDHB11   Affinity Capture-MS Homo sapiens 41 APEX1 328 Affinity Capture-RNA Homo sapiens 42 PCDHA4 56144 Affinity Capture-MS Homo sapiens 43 KCNE3   Affinity Capture-MS Homo sapiens 44 BDKRB1 623 Two-hybrid Homo sapiens 45 TEX264 51368 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 46 CHRNA9   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 47 OR1M1   Affinity Capture-MS Homo sapiens 48 MOV10 4343 Affinity Capture-RNA Homo sapiens 49 PCDHGC4   Affinity Capture-MS Homo sapiens 50 KCNA10   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 51 GDPD5 81544 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 52 ZNRF4   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 53 LRRTM1 347730 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 54 SLC4A8 9498 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 55 MARCH4   Affinity Capture-MS Homo sapiens 56 CNGA3   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 57 FAM189A2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 58 KCNJ6   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 59 ACVR1C   Affinity Capture-MS Homo sapiens 60 KCNA2   Affinity Capture-MS Homo sapiens 61 IL17RC 84818 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 62 BTNL3   Affinity Capture-MS Homo sapiens 63 DERL1 79139 Proximity Label-MS Homo sapiens 64 CHRNB1   Affinity Capture-MS Homo sapiens 65 MRAP2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 66 PDE3A   Affinity Capture-MS Homo sapiens 67 C3orf52   Affinity Capture-MS Homo sapiens 68 KCNA5   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 69 CCDC28A   Affinity Capture-MS Homo sapiens 70 CHRND   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens View the network

Pathways in which C1orf43 is involved

No pathways found