Gene description for CXCR4
Gene name	chemokine (C-X-C motif) receptor 4
Gene symbol	CXCR4
Other names/aliases	CD184 D2S201E FB22 HM89 HSY3RR LAP-3 LAP3 LCR1 LESTR NPY3R NPYR NPYRL NPYY3R WHIM WHIMS
Species	Homo sapiens
Database cross references - CXCR4
ExoCarta	ExoCarta_7852
Entrez Gene	7852
HGNC	2561
MIM	162643
UniProt	P61073
CXCR4 identified in exosomes derived from the following tissue/cell type
B cells	20458337
B cells	20458337
B cells	20458337
Platelets	25332113
Platelets	25332113
Platelets	25332113
T cells	11907077

Gene ontology annotations for CXCR4

Molecular Function     virus receptor activity GO:0001618 IEA     cytokine binding GO:0019955 IEA     actin binding GO:0003779 IDA     ubiquitin protein ligase binding GO:0031625 IPI     myosin light chain binding GO:0032027 IDA     coreceptor activity GO:0015026 TAS     ubiquitin binding GO:0043130 IDA     C-X-C chemokine receptor activity GO:0016494 NAS     protein binding GO:0005515 IPI     G-protein coupled receptor activity GO:0004930 TAS Biological Process     germ cell development GO:0007281 IEA     dendritic cell chemotaxis GO:0002407 TAS     activation of MAPK activity GO:0000187 TAS     neuron migration GO:0001764 IEA     brain development GO:0007420 IEA     patterning of blood vessels GO:0001569 IEA     positive regulation of oligodendrocyte differentiation GO:0048714 ISS     entry into host cell GO:0030260 TAS     neutrophil activation GO:0042119 IEA     ameboidal-type cell migration GO:0001667 IEA     viral process GO:0016032 TAS     chemokine-mediated signaling pathway GO:0070098 NAS     motor neuron axon guidance GO:0008045 IEA     G-protein coupled receptor signaling pathway GO:0007186 IDA     positive regulation of cytosolic calcium ion concentration GO:0007204 TAS     calcium-mediated signaling GO:0019722 IMP     viral entry into host cell GO:0046718 IEA     response to virus GO:0009615 TAS     germ cell migration GO:0008354 IEA     neural precursor cell proliferation GO:0061351 IEA     response to hypoxia GO:0001666 IEP     apoptotic process GO:0006915 TAS     inflammatory response GO:0006954 TAS     regulation of chemotaxis GO:0050920 IMP     regulation of cell migration GO:0030334 IEA     T cell proliferation GO:0042098 IEA     myelin maintenance GO:0043217 ISS     cellular response to cytokine stimulus GO:0071345 IDA Subcellular Localization     cell surface GO:0009986 IDA     growth cone GO:0030426 IEA     cell-cell junction GO:0005911 IEA     lysosome GO:0005764 IDA     early endosome GO:0005769 IDA     cytoplasmic membrane-bounded vesicle GO:0016023 IDA     extracellular exosome GO:0070062 IDA     cytosol GO:0005829 TAS     cytoplasmic vesicle GO:0031410 IDA     integral component of membrane GO:0016021 IEA     cytoplasm GO:0005737 TAS     cell leading edge GO:0031252 IDA     plasma membrane GO:0005886 TAS     late endosome GO:0005770 IDA     external side of plasma membrane GO:0009897 IEA