Gene description for EXOC6
Gene name exocyst complex component 6
Gene symbol EXOC6
Other names/aliases EXOC6A
SEC15
SEC15L
SEC15L1
SEC15L3
Sec15p
Species Homo sapiens
 Database cross references - EXOC6
ExoCarta ExoCarta_54536
Entrez Gene 54536
HGNC 23196
MIM 609672
UniProt Q8TAG9  
 EXOC6 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for EXOC6
Biological Process
    membrane organization GO:0061024 TAS
    protein transport GO:0015031 IEA
    cellular protein metabolic process GO:0044267 TAS
    organelle organization GO:0006996 TAS
    erythrocyte differentiation GO:0030218 IEA
    vesicle docking involved in exocytosis GO:0006904 IEA
Subcellular Localization
    plasma membrane GO:0005886 TAS
    exocyst GO:0000145 IEA
    cytosol GO:0005829 TAS
 Experiment description of studies that identified EXOC6 in exosomes
1
Experiment ID 217
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101
EV Cytosolic markers
✔
CD81|CD9|CD63
EV Membrane markers
✘ EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for EXOC6
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which EXOC6 is involved
PathwayEvidenceSource
Insulin processing TAS Reactome
Translocation of GLUT4 to the plasma membrane TAS Reactome
VxPx cargo-targeting to cilium TAS Reactome





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