Experiment description of studies that identified FAM174A in exosomes

1 Experiment ID 224 MISEV standards ✔ EM|AFM Biophysical techniques ✔ Alix|TSG101|CD63|CD81 Enriched markers ✔ GOLGA2 Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25944692     Organism Homo sapiens Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S" Journal name Oncotarget Publication year 2015 Sample Neuroblastoma cells Sample name SH-SY5Y Isolation/purification methods Differential centrifugation Ultracentrifugation OptiPrep density gradient Flotation density 1.10 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting

Protein-protein interactions for FAM174A

Protein Interactor ExoCarta ID Identification method PubMed Species 1 SEC22B 9554 Two-hybrid Homo sapiens 2 ATR   Affinity Capture-MS Homo sapiens 3 RPS6KA5 9252 Affinity Capture-MS Homo sapiens 4 SLC25A40   Affinity Capture-MS Homo sapiens 5 DNAJC11 55735 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 6 BCKDK 10295 Affinity Capture-MS Homo sapiens 7 VMP1 81671 Affinity Capture-MS Homo sapiens 8 SKIV2L 6499 Affinity Capture-MS Homo sapiens 9 MSH6 2956 Affinity Capture-MS Homo sapiens 10 GALNT1 2589 Affinity Capture-MS Homo sapiens 11 CTPS2 56474 Affinity Capture-MS Homo sapiens 12 CBR4   Affinity Capture-MS Homo sapiens 13 TNPO1 3842 Affinity Capture-MS Homo sapiens 14 NCALD 83988 Affinity Capture-MS Homo sapiens 15 SMIM1 388588 Two-hybrid Homo sapiens 16 EIF2B2 8892 Affinity Capture-MS Homo sapiens 17 MTPAP 55149 Affinity Capture-MS Homo sapiens 18 CAND2 23066 Affinity Capture-MS Homo sapiens 19 GAK 2580 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 20 TUBB8 347688 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 21 NDUFB5 4711 Affinity Capture-MS Homo sapiens 22 ATP12A 479 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 23 IRAK1   Affinity Capture-MS Homo sapiens 24 TMEM203   Two-hybrid Homo sapiens 25 CDK5RAP1   Affinity Capture-MS Homo sapiens 26 RPS6KA4 8986 Affinity Capture-MS Homo sapiens 27 CNP 1267 Affinity Capture-MS Homo sapiens 28 GOSR2 9570 Two-hybrid Homo sapiens 29 TBC1D8   Affinity Capture-MS Homo sapiens 30 GATB   Affinity Capture-MS Homo sapiens 31 INTS1 26173 Affinity Capture-MS Homo sapiens 32 C4orf3   Two-hybrid Homo sapiens 33 LTN1 26046 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 34 FAM20B 9917 Affinity Capture-MS Homo sapiens 35 PI4KA 5297 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 36 SPG7   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 37 TELO2 9894 Affinity Capture-MS Homo sapiens 38 PDCD10 11235 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 39 CHD1L 9557 Affinity Capture-MS Homo sapiens 40 L2HGDH   Affinity Capture-MS Homo sapiens 41 HEATR3 55027 Affinity Capture-MS Homo sapiens 42 STK26 51765 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 43 PC 5091 Affinity Capture-MS Homo sapiens 44 TMEM65 157378 Two-hybrid Homo sapiens 45 TMEM168 64418 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 46 TMEM222 84065 Two-hybrid Homo sapiens 47 SLC39A11   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 48 HARS2 23438 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 49 SPAG9 9043 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 50 RAB13 5872 Affinity Capture-MS Homo sapiens 51 GIMAP1   Two-hybrid Homo sapiens 52 TM9SF4 9777 Affinity Capture-MS Homo sapiens 53 STX8 9482 Two-hybrid Homo sapiens 54 TBC1D23 55773 Affinity Capture-MS Homo sapiens 55 OAF 220323 Affinity Capture-MS Homo sapiens 56 C14orf180   Two-hybrid Homo sapiens 57 MAD2L2 10459 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 58 SMC2 10592 Affinity Capture-MS Homo sapiens 59 PRPS1 5631 Affinity Capture-MS Homo sapiens 60 SERP1 27230 Two-hybrid Homo sapiens 61 AASS   Affinity Capture-MS Homo sapiens 62 ATP2A3 489 Affinity Capture-MS Homo sapiens 63 UGDH 7358 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 64 IPO8 10526 Affinity Capture-MS Homo sapiens 65 GIMAP5   Two-hybrid Homo sapiens 66 FANCD2   Affinity Capture-MS Homo sapiens 67 GOPC 57120 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 68 CCDC47 57003 Affinity Capture-MS Homo sapiens 69 HSPA12B 116835 Affinity Capture-MS Homo sapiens 70 DFNA5 1687 Affinity Capture-MS Homo sapiens 71 BET1 10282 Two-hybrid Homo sapiens 72 SPATA5L1 79029 Affinity Capture-MS Homo sapiens 73 LCLAT1 253558 Affinity Capture-MS Homo sapiens 74 ACSF2 80221 Affinity Capture-MS Homo sapiens 75 VWA8 23078 Affinity Capture-MS Homo sapiens 76 EHD1 10938 Affinity Capture-MS Homo sapiens 77 SLC25A29   Affinity Capture-MS Homo sapiens 78 FASTKD1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 79 CINP   Affinity Capture-MS Homo sapiens 80 GPN3   Affinity Capture-MS Homo sapiens 81 SAMHD1 25939 Affinity Capture-MS Homo sapiens 82 METTL13 51603 Affinity Capture-MS Homo sapiens 83 DDX19B 11269 Affinity Capture-MS Homo sapiens 84 HEATR1 55127 Affinity Capture-MS Homo sapiens 85 PRAME   Affinity Capture-MS Homo sapiens 86 TREX1   Two-hybrid Homo sapiens 87 KIAA1147   Affinity Capture-MS Homo sapiens 88 IPO7 10527 Affinity Capture-MS Homo sapiens 89 FUT8 2530 Affinity Capture-MS Homo sapiens 90 BNIP1 662 Two-hybrid Homo sapiens 91 C17orf75 64149 Affinity Capture-MS Homo sapiens 92 CTU2 348180 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 93 VPS51 738 Affinity Capture-MS Homo sapiens 94 SFXN3 81855 Affinity Capture-MS Homo sapiens 95 EIF2B5 8893 Affinity Capture-MS Homo sapiens 96 TUBA1A 7846 Affinity Capture-MS Homo sapiens 97 CPS1 1373 Affinity Capture-MS Homo sapiens 98 MTX2 10651 Affinity Capture-MS Homo sapiens 99 RNF213 57674 Affinity Capture-MS Homo sapiens 100 PDXDC1 23042 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 101 FAM118B   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 102 TUBA1C 84790 Affinity Capture-MS Homo sapiens 103 TAMM41   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 104 TMEM243   Two-hybrid Homo sapiens 105 GFPT2 9945 Affinity Capture-MS Homo sapiens 106 OPA1 4976 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 107 EXOC6 54536 Affinity Capture-MS Homo sapiens 108 RLIM 51132 Affinity Capture-MS Homo sapiens 109 ALDH3B1 221 Affinity Capture-MS Homo sapiens 110 SMC1A 8243 Affinity Capture-MS Homo sapiens 111 SLFN5 162394 Affinity Capture-MS Homo sapiens 112 TNPO2 30000 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 113 ATP2B4 493 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 114 TRMT2A 27037 Affinity Capture-MS Homo sapiens 115 ATP2C1 27032 Affinity Capture-MS Homo sapiens 116 EIF2B4 8890 Affinity Capture-MS Homo sapiens 117 TNFAIP2 7127 Affinity Capture-MS Homo sapiens 118 GNL3L 54552 Affinity Capture-MS Homo sapiens 119 PEX6   Affinity Capture-MS Homo sapiens 120 HEATR6   Affinity Capture-MS Homo sapiens 121 DNAJB14   Affinity Capture-MS Homo sapiens 122 PLAA 9373 Affinity Capture-MS Homo sapiens 123 TUBB 203068 Affinity Capture-MS Homo sapiens 124 SLC30A2   Two-hybrid Homo sapiens 125 ELMO3 79767 Affinity Capture-MS Homo sapiens 126 VAPB 9217 Two-hybrid Homo sapiens 127 TUBGCP5 114791 Affinity Capture-MS Homo sapiens 128 C14orf1 11161 Two-hybrid Homo sapiens 129 RTP2   Two-hybrid Homo sapiens 130 ATP2B1 490 Affinity Capture-MS Homo sapiens 131 NCAPH2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 132 NPTN 27020 Affinity Capture-MS Homo sapiens 133 STK17B 9262 Affinity Capture-MS Homo sapiens 134 CBWD2   Affinity Capture-MS Homo sapiens 135 CDC42EP1 11135 Affinity Capture-MS Homo sapiens 136 TCP11L1 55346 Affinity Capture-MS Homo sapiens 137 MADD 8567 Affinity Capture-MS Homo sapiens 138 CBWD3   Affinity Capture-MS Homo sapiens 139 TNPO3 23534 Affinity Capture-MS Homo sapiens 140 FKBP8 23770 Two-hybrid Homo sapiens 141 MYO19   Affinity Capture-MS Homo sapiens 142 TMEM42   Two-hybrid Homo sapiens 143 ATXN10 25814 Affinity Capture-MS Homo sapiens 144 GBF1 8729 Affinity Capture-MS Homo sapiens 145 TMEM11 8834 Two-hybrid Homo sapiens 146 PRPSAP1 5635 Affinity Capture-MS Homo sapiens 147 FBXL12 54850 Affinity Capture-MS Homo sapiens 148 PLLP   Two-hybrid Homo sapiens 149 GDAP1 54332 Affinity Capture-MS Homo sapiens 150 PARP14 54625 Affinity Capture-MS Homo sapiens 151 CECR5 27440 Affinity Capture-MS Homo sapiens 152 SAAL1 113174 Affinity Capture-MS Homo sapiens 153 UMPS 7372 Affinity Capture-MS Homo sapiens 154 FAM91A1 157769 Affinity Capture-MS Homo sapiens 155 MTOR 2475 Affinity Capture-MS Homo sapiens 156 MROH1 727957 Affinity Capture-MS Homo sapiens 157 CDC45   Affinity Capture-MS Homo sapiens 158 RAF1 5894 Affinity Capture-MS Homo sapiens 159 SPATA5 166378 Affinity Capture-MS Homo sapiens 160 B3GAT3 26229 Affinity Capture-MS Homo sapiens 161 NCAPG2 54892 Affinity Capture-MS Homo sapiens 162 METTL9 51108 Affinity Capture-MS Homo sapiens 163 PPAPDC2   Two-hybrid Homo sapiens 164 CCDC167   Two-hybrid Homo sapiens 165 DYM   Affinity Capture-MS Homo sapiens 166 THADA 63892 Affinity Capture-MS Homo sapiens 167 CBWD1 55871 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 168 RAD51C   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 169 ACSL1 2180 Affinity Capture-MS Homo sapiens 170 ATP2B3 492 Affinity Capture-MS Homo sapiens 171 RAB18 22931 Affinity Capture-MS Homo sapiens 172 TUBB2A 7280 Affinity Capture-MS Homo sapiens 173 TMEM239   Two-hybrid Homo sapiens 174 CCZ1 51622 Affinity Capture-MS Homo sapiens 175 CMTM7   Two-hybrid Homo sapiens 176 UHRF1BP1L 23074 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 177 TOR1AIP2 163590 Affinity Capture-MS Homo sapiens 178 TRAPPC5 126003 Affinity Capture-MS Homo sapiens 179 PEX1 5189 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 180 TP53 7157 Negative Genetic Homo sapiens 181 EHD4 30844 Affinity Capture-MS Homo sapiens 182 COQ5   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 183 ATP1A3 478 Affinity Capture-MS Homo sapiens 184 PEX19 5824 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 185 MAP1S 55201 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 186 SLC39A7 7922 Affinity Capture-MS Homo sapiens 187 HLTF   Affinity Capture-MS Homo sapiens 188 LCK 3932 Protein-peptide Homo sapiens 189 TUBB3 10381 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 190 INTS2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 191 FANCI 55215 Affinity Capture-MS Homo sapiens 192 GPD1L 23171 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 193 PPTC7 160760 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 194 TTK 7272 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 195 OTUB1 55611 Affinity Capture-MS Homo sapiens 196 UCKL1 54963 Affinity Capture-MS Homo sapiens 197 TMLHE 55217 Affinity Capture-MS Homo sapiens 198 TUBB4A 10382 Affinity Capture-MS Homo sapiens 199 ECHDC1 55862 Affinity Capture-MS Homo sapiens 200 GUF1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 201 NF1 4763 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 202 TBRG4 9238 Affinity Capture-MS Homo sapiens 203 KDELR2 11014 Affinity Capture-MS Homo sapiens 204 IPO4 79711 Affinity Capture-MS Homo sapiens 205 STXBP2 6813 Affinity Capture-MS Homo sapiens 206 ATP2B2 491 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 207 SEC22A   Two-hybrid Homo sapiens 208 SMCO4   Two-hybrid Homo sapiens 209 ASPHD2   Affinity Capture-MS Homo sapiens 210 ACSF3 197322 Affinity Capture-MS Homo sapiens 211 PGM3 5238 Affinity Capture-MS Homo sapiens 212 ARF5 381 Affinity Capture-MS Homo sapiens 213 ABHD17B 51104 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 214 HSPA12A 259217 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 215 ANKRD46 157567 Two-hybrid Homo sapiens 216 JAK1 3716 Affinity Capture-MS Homo sapiens 217 CCRN4L   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens View the network

Pathways in which FAM174A is involved

No pathways found