Gene description for TOR1AIP2
Gene name torsin A interacting protein 2
Gene symbol TOR1AIP2
Other names/aliases IFRG15
LULL1
NET9
Species Homo sapiens
 Database cross references - TOR1AIP2
ExoCarta ExoCarta_163590
Entrez Gene 163590
HGNC 24055
MIM 614513
UniProt Q9H496   Q8NFQ8  
 TOR1AIP2 identified in exosomes derived from the following tissue/cell type
Endothelial cells 26027894    
 Gene ontology annotations for TOR1AIP2
Molecular Function
    ATPase activator activity GO:0001671 IDA
    protein binding GO:0005515 IPI
    ATPase binding GO:0051117 IPI
Biological Process
    positive regulation of ATPase activity GO:0032781 IDA
    endoplasmic reticulum organization GO:0007029 IMP
    protein localization to nuclear envelope GO:0090435 IDA
Subcellular Localization
    integral component of membrane GO:0016021 IEA
    endoplasmic reticulum membrane GO:0005789 IEA
    cytoplasm GO:0005737 IDA
    nuclear membrane GO:0031965 IEA
    intracellular membrane-bounded organelle GO:0043231 IDA
    endoplasmic reticulum GO:0005783 IDA
    nucleus GO:0005634 IDA
 Experiment description of studies that identified TOR1AIP2 in exosomes
1
Experiment ID 226
ISEV standards
EM
EV Biophysical techniques
GAPDH
EV Cytosolic markers
CD9|FLOT1
EV Membrane markers
LMNA|H2AFX|ATP5A1|TOMM20
EV Negative markers
EV Particle analysis
Identified molecule mRNA
Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
PubMed ID 26027894    
Organism Homo sapiens
Experiment description Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting
Authors Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar
Journal name Journal of Extracellular Vesicles
Publication year 2015
Sample Endothelial cells
Sample name HMEC-1
Isolation/purification methods Differential ultracentrifugation
Sucrose density gradient
Flotation density 1.10 g/mL
Molecules identified in the study miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA
Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting
 Protein-protein interactions for TOR1AIP2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which TOR1AIP2 is involved
No pathways found





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