Gene description for CUL4B
Gene name cullin 4B
Gene symbol CUL4B
Other names/aliases CUL-4B
MRXHF2
MRXS15
MRXSC
SFM2
Species Homo sapiens
 Database cross references - CUL4B
ExoCarta ExoCarta_8450
Vesiclepedia VP_8450
Entrez Gene 8450
HGNC 2555
MIM 300304
UniProt Q13620  
 CUL4B identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Mesenchymal stem cells 36408942    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Prostate cancer cells 25844599    
Urine 19056867    
 Gene ontology annotations for CUL4B
Molecular Function
    damaged DNA binding GO:0003684 IDA
    protein binding GO:0005515 IPI
    ubiquitin protein ligase binding GO:0031625 IBA
Biological Process
    G1/S transition of mitotic cell cycle GO:0000082 NAS
    protein polyubiquitination GO:0000209 IEA
    ubiquitin-dependent protein catabolic process GO:0006511 IEA
    DNA damage response GO:0006974 IBA
    DNA damage response GO:0006974 ISS
    gene expression GO:0010467 IEA
    proteasomal protein catabolic process GO:0010498 IDA
    proteasomal protein catabolic process GO:0010498 IMP
    protein ubiquitination GO:0016567 IBA
    protein ubiquitination GO:0016567 IMP
    neuron projection development GO:0031175 IEA
    cellular response to UV GO:0034644 ISS
    ribosome biogenesis GO:0042254 IMP
    positive regulation of protein catabolic process GO:0045732 IEA
    astrocyte differentiation GO:0048708 IEA
    UV-damage excision repair GO:0070914 IDA
    positive regulation of G1/S transition of mitotic cell cycle GO:1900087 IEA
Subcellular Localization
    nucleus GO:0005634 NAS
    nucleoplasm GO:0005654 IDA
    nucleoplasm GO:0005654 TAS
    cytosol GO:0005829 IDA
    Cul4A-RING E3 ubiquitin ligase complex GO:0031464 EXP
    Cul4B-RING E3 ubiquitin ligase complex GO:0031465 IBA
    Cul4B-RING E3 ubiquitin ligase complex GO:0031465 IDA
    extracellular exosome GO:0070062 HDA
    Cul4-RING E3 ubiquitin ligase complex GO:0080008 IDA
 Experiment description of studies that identified CUL4B in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
6
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
7
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
8
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
9
Experiment ID 207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
10
Experiment ID 208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
11
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
12
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
13
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
14
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
15
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
16
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
17
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
18
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
19
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
20
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
21
Experiment ID 274
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel resistant
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.18 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Flow cytometry
Western blotting
22
Experiment ID 63
MISEV standards
✘ Biophysical techniques
✔
AQP2
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for CUL4B
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HIST2H2BE 8349
Affinity Capture-MS Homo sapiens
2 HDAC2 3066
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
3 KRT1 3848
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 KPNA1 3836
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
5 LDHB 3945
Affinity Capture-MS Homo sapiens
6 ANKRD9  
Affinity Capture-MS Homo sapiens
7 C9orf78 51759
Affinity Capture-MS Homo sapiens
8 UBC 7316
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
9 CSTA 1475
Affinity Capture-MS Homo sapiens
10 KPNA2 3838
Reconstituted Complex Homo sapiens
11 HSP90AA2P 3324
Affinity Capture-MS Homo sapiens
12 WDR26 80232
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
13 SOX2  
Affinity Capture-MS Homo sapiens
14 WDR62  
Affinity Capture-Western Homo sapiens
15 HDAC3 8841
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Co-localization Homo sapiens
16 WDR76  
Affinity Capture-Western Homo sapiens
17 DDA1  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
18 CCS 9973
Affinity Capture-MS Homo sapiens
19 H2AFV 94239
Affinity Capture-MS Homo sapiens
20 PIP4K2B 8396
Affinity Capture-MS Homo sapiens
21 OIP5  
Affinity Capture-Western Homo sapiens
22 HIST1H2AI 8329
Affinity Capture-MS Homo sapiens
23 HSP90B1 7184
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
24 SNRPD3 6634
Affinity Capture-MS Homo sapiens
25 GPS1 2873
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
26 WDR5 11091
Affinity Capture-Western Homo sapiens
27 NUDT16L1 84309
Affinity Capture-MS Homo sapiens
28 MTA2 9219
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
29 RBM14 10432
Affinity Capture-MS Homo sapiens
30 HSPA9 3313
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
31 RPL36AP37  
Affinity Capture-MS Homo sapiens
32 ANXA7 310
Affinity Capture-MS Homo sapiens
33 PIP4K2C 79837
Affinity Capture-MS Homo sapiens
34 SNRNP70 6625
Affinity Capture-MS Homo sapiens
35 USP11 8237
Affinity Capture-MS Homo sapiens
36 PGAM5 192111
Affinity Capture-MS Homo sapiens
37 CTBP1 1487
Affinity Capture-Western Homo sapiens
38 HIST1H2AG 8969
Affinity Capture-MS Homo sapiens
39 C17orf85  
Affinity Capture-RNA Homo sapiens
40 TUFM 7284
Affinity Capture-MS Homo sapiens
41 MPPED1  
Affinity Capture-MS Homo sapiens
42 HIST1H2AM 8336
Affinity Capture-MS Homo sapiens
43 RPL21P16  
Affinity Capture-MS Homo sapiens
44 PABPC1 26986
Affinity Capture-MS Homo sapiens
45 DLGAP3  
Affinity Capture-MS Homo sapiens
46 TTN 7273
Affinity Capture-MS Homo sapiens
47 OGT 8473
Affinity Capture-MS Homo sapiens
48 RPL31 6160
Affinity Capture-MS Homo sapiens
49 KRT9 3857
Affinity Capture-MS Homo sapiens
50 SYNCRIP 10492
Affinity Capture-MS Homo sapiens
51 HIST1H1C 3006
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
52 ENO1 2023
Affinity Capture-MS Homo sapiens
53 TUBA1C 84790
Affinity Capture-MS Homo sapiens
54 CUL2 8453
Affinity Capture-MS Homo sapiens
55 COMMD1 150684
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
56 LRP1B 53353
Affinity Capture-MS Homo sapiens
57 SLC25A5 292
Affinity Capture-MS Homo sapiens
58 TWIST1  
Affinity Capture-Western Homo sapiens
59 KRT85  
Affinity Capture-MS Homo sapiens
60 DTL  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
61 KIF15 56992
Affinity Capture-MS Homo sapiens
62 TTLL7  
Affinity Capture-MS Homo sapiens
63 CSN2 1447
Affinity Capture-MS Homo sapiens
64 CDC25A  
Affinity Capture-Western Homo sapiens
65 SIRT7  
Affinity Capture-MS Homo sapiens
66 SRSF4 6429
Affinity Capture-MS Homo sapiens
67 QPCT 25797
Affinity Capture-MS Homo sapiens
68 ACTBL2 345651
Affinity Capture-MS Homo sapiens
69 FKBP8 23770
Affinity Capture-Western Homo sapiens
70 DCAF16 54876
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
71 EPRS 2058
Co-fractionation Homo sapiens
72 RBBP4 5928
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
73 DCAF8 50717
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
74 TUBA4A 7277
Affinity Capture-MS Homo sapiens
75 PRMT5 10419
Co-localization Homo sapiens
Co-localization Homo sapiens
Affinity Capture-MS Homo sapiens
76 CRYBA4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
77 RPL35A 6165
Affinity Capture-MS Homo sapiens
78 HSPA1A 3303
Affinity Capture-MS Homo sapiens
79 TBL1X 6907
Affinity Capture-Western Homo sapiens
80 ST7  
Biochemical Activity Homo sapiens
81 DCAF15  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
82 HIST1H2AJ 8331
Affinity Capture-MS Homo sapiens
83 SUPT16H 11198
Affinity Capture-Western Homo sapiens
84 VASP 7408
Co-fractionation Homo sapiens
85 RPS16 6217
Affinity Capture-MS Homo sapiens
86 WDR77 79084
Co-localization Homo sapiens
Co-localization Homo sapiens
Affinity Capture-MS Homo sapiens
87 STUB1 10273
Co-fractionation Homo sapiens
88 YBX1 4904
Affinity Capture-MS Homo sapiens
89 GRK5 2869
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
90 CLPX 10845
Affinity Capture-MS Homo sapiens
91 B3GNT4  
Affinity Capture-MS Homo sapiens
92 ALDH9A1 223
Affinity Capture-MS Homo sapiens
93 RPL6 6128
Affinity Capture-MS Homo sapiens
94 RWDD4 201965
Affinity Capture-MS Homo sapiens
95 MTA1 9112
Reconstituted Complex Homo sapiens
Co-localization Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
96 ZEB1  
Affinity Capture-Western Homo sapiens
97 TLE1 7088
Affinity Capture-MS Homo sapiens
98 HSP90AA1 3320
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
99 SIRT1  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
100 DCAF4L2 138009
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
101 PSMA1 5682
Co-fractionation Homo sapiens
102 PWP1 11137
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
103 KRT24 192666
Affinity Capture-MS Homo sapiens
104 RPS24 6229
Affinity Capture-MS Homo sapiens
105 NCL 4691
Affinity Capture-MS Homo sapiens
106 CDK4 1019
Affinity Capture-MS Homo sapiens
107 KRT13 3860
Affinity Capture-MS Homo sapiens
108 RPL23A 6147
Affinity Capture-MS Homo sapiens
109 DNMT1 1786
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
110 HSPA1B 3304
Affinity Capture-MS Homo sapiens
111 TRPC4AP  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
112 HNRNPH1 3187
Affinity Capture-MS Homo sapiens
113 MCM3 4172
Affinity Capture-MS Homo sapiens
114 NCBP1 4686
Affinity Capture-RNA Homo sapiens
115 LYZ 4069
Affinity Capture-MS Homo sapiens
116 CTBP2 1488
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
117 RPA2 6118
Proximity Label-MS Homo sapiens
118 VPRBP 9730
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
119 SPSB4  
Affinity Capture-MS Homo sapiens
120 HSP90AB1 3326
Affinity Capture-MS Homo sapiens
121 CAND1 55832
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
122 ANKRD39  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
123 RPL21P19  
Affinity Capture-MS Homo sapiens
124 WDTC1 23038
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
125 LGALS3BP 3959
Affinity Capture-MS Homo sapiens
126 RPS18 6222
Affinity Capture-MS Homo sapiens
127 NCOR1  
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
128 DAZAP1 26528
Affinity Capture-MS Homo sapiens
129 RBM3 5935
Affinity Capture-MS Homo sapiens
130 FBXO44  
Affinity Capture-Western Homo sapiens
131 COPS6 10980
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
132 BRWD3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
133 PCBD1 5092
Affinity Capture-MS Homo sapiens
134 ARID4B  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
135 TAF15 8148
Affinity Capture-MS Homo sapiens
136 POC1B 282809
Affinity Capture-Western Homo sapiens
137 KHSRP 8570
Affinity Capture-MS Homo sapiens
138 HSPA7 3311
Affinity Capture-MS Homo sapiens
139 GRWD1 83743
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
140 TIAL1 7073
Affinity Capture-MS Homo sapiens
141 CUL1 8454
Cross-Linking-MS (XL-MS) Homo sapiens
142 PHF1  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
143 CTPS1 1503
Affinity Capture-MS Homo sapiens
144 SOCS3 9021
Affinity Capture-MS Homo sapiens
145 USP7 7874
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
146 DCAF17  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
147 AMBRA1  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
148 CALM2 805
Affinity Capture-MS Homo sapiens
149 ACTA2 59
Affinity Capture-MS Homo sapiens
150 USP15 9958
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
151 MIB1 57534
Proximity Label-MS Homo sapiens
152 FHL3 2275
Affinity Capture-MS Homo sapiens
153 RBX1 9978
Affinity Capture-MS Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
154 RPL4 6124
Affinity Capture-MS Homo sapiens
155 ERCC6  
Affinity Capture-Western Homo sapiens
156 DCAF12 25853
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
157 TMEM43 79188
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
158 SNRPB 6628
Affinity Capture-MS Homo sapiens
159 ZEB2  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
160 SNRPD1 6632
Affinity Capture-MS Homo sapiens
161 KRT14 3861
Affinity Capture-MS Homo sapiens
162 DCAF10  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
163 RPLP0 6175
Affinity Capture-MS Homo sapiens
164 COPS7B 64708
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
165 ZCCHC11 23318
Affinity Capture-MS Homo sapiens
166 Ksr1  
Affinity Capture-MS Mus musculus
167 CCBL2 56267
Affinity Capture-MS Homo sapiens
168 GPS2  
Affinity Capture-Western Homo sapiens
169 EIF4B 1975
Co-fractionation Homo sapiens
170 ASB6 140459
Affinity Capture-MS Homo sapiens
171 HNRNPD 3184
Affinity Capture-MS Homo sapiens
172 TUBB 203068
Affinity Capture-MS Homo sapiens
173 RPL7P32  
Affinity Capture-MS Homo sapiens
174 USP4 7375
Affinity Capture-MS Homo sapiens
175 COPS7A 50813
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
176 AIFM1 9131
Co-fractionation Homo sapiens
177 KDM4D  
Affinity Capture-MS Homo sapiens
178 RPS2 6187
Affinity Capture-MS Homo sapiens
179 GLMN 11146
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
180 MRPS11  
Affinity Capture-MS Homo sapiens
181 UBXN7 26043
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
182 PHIP 55023
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
183 TUBB4B 10383
Affinity Capture-MS Homo sapiens
184 EGFR 1956
Affinity Capture-MS Homo sapiens
185 HSD17B10 3028
Affinity Capture-MS Homo sapiens
186 FUS 2521
Affinity Capture-MS Homo sapiens
187 SERINC5 256987
Affinity Capture-MS Homo sapiens
188 TFG 10342
Affinity Capture-MS Homo sapiens
189 CDK2 1017
Affinity Capture-MS Homo sapiens
190 PIP4K2A 5305
Affinity Capture-MS Homo sapiens
191 RPL29P30  
Affinity Capture-MS Homo sapiens
192 SERBP1 26135
Affinity Capture-MS Homo sapiens
193 FN3KRP 79672
Affinity Capture-MS Homo sapiens
194 CSNK2A2 1459
Affinity Capture-MS Homo sapiens
195 BLMH 642
Affinity Capture-MS Homo sapiens
196 EEF1A2 1917
Affinity Capture-MS Homo sapiens
197 HNRNPAB 3182
Affinity Capture-MS Homo sapiens
198 DDB1 1642
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Co-localization Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
199 FAM103A1  
Affinity Capture-MS Homo sapiens
200 GCNT3 9245
Affinity Capture-MS Homo sapiens
201 RPL13 6137
Affinity Capture-MS Homo sapiens
202 HNRNPH2 3188
Affinity Capture-MS Homo sapiens
203 TTC1 7265
Co-fractionation Homo sapiens
204 C9orf117  
Affinity Capture-MS Homo sapiens
205 TP53 7157
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
206 RFWD2  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
207 RPS4X 6191
Affinity Capture-MS Homo sapiens
208 FAM184A 79632
Affinity Capture-MS Homo sapiens
209 NHP2L1 4809
Co-fractionation Homo sapiens
210 HNRNPK 3190
Affinity Capture-MS Homo sapiens
211 DCD 117159
Affinity Capture-MS Homo sapiens
212 ASB8  
Affinity Capture-MS Homo sapiens
213 YBX3 8531
Affinity Capture-MS Homo sapiens
214 HIST1H2AL 8332
Affinity Capture-MS Homo sapiens
215 PRDX1 5052
Affinity Capture-MS Homo sapiens
216 C1QBP 708
Affinity Capture-MS Homo sapiens
217 MTA3 57504
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
218 DCAF4  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
219 RCOR1  
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
220 CUL4A 8451
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
221 KRT76 51350
Affinity Capture-MS Homo sapiens
222 HNRNPC 3183
Co-fractionation Homo sapiens
223 TCEAL2  
Affinity Capture-MS Homo sapiens
224 RPL26L1 51121
Affinity Capture-MS Homo sapiens
225 SNRPG 6637
Affinity Capture-MS Homo sapiens
226 SNRPE 6635
Affinity Capture-MS Homo sapiens
227 PHF21A  
Affinity Capture-Western Homo sapiens
228 SSB 6741
Affinity Capture-MS Homo sapiens
229 XRN2 22803
Affinity Capture-MS Homo sapiens
230 HNRNPCL1 343069
Affinity Capture-MS Homo sapiens
231 HNRNPR 10236
Affinity Capture-MS Homo sapiens
232 APBB1  
Affinity Capture-MS Homo sapiens
233 SOX9  
Affinity Capture-Western Homo sapiens
234 CAPZB 832
Affinity Capture-MS Homo sapiens
235 SART3 9733
Affinity Capture-MS Homo sapiens
236 WDR48 57599
Affinity Capture-MS Homo sapiens
237 Ddb1 13194
Affinity Capture-MS Mus musculus
Affinity Capture-MS Mus musculus
238 DYNC1LI2 1783
Proximity Label-MS Homo sapiens
239 MCM2 4171
Affinity Capture-MS Homo sapiens
240 DCAF12L2  
Affinity Capture-MS Homo sapiens
241 LINC01587  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
242 SUV39H1  
Affinity Capture-Western Homo sapiens
243 TWIST2  
Affinity Capture-Western Homo sapiens
244 EWSR1 2130
Affinity Capture-MS Homo sapiens
245 SYT2  
Affinity Capture-MS Homo sapiens
246 KRT5 3852
Affinity Capture-MS Homo sapiens
247 SRSF3 6428
Affinity Capture-MS Homo sapiens
248 HIST2H2AC 8338
Affinity Capture-MS Homo sapiens
249 PABPC4 8761
Affinity Capture-MS Homo sapiens
250 HSPA8 3312
Affinity Capture-MS Homo sapiens
251 NF2 4771
Affinity Capture-MS Homo sapiens
252 RPL27 6155
Affinity Capture-MS Homo sapiens
253 IRS4 8471
Affinity Capture-MS Homo sapiens
254 MYO18A 399687
Affinity Capture-MS Homo sapiens
255 RGS2  
Affinity Capture-Western Homo sapiens
256 RPL9 6133
Affinity Capture-MS Homo sapiens
257 CUL4B 8450
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
258 PARK2  
Affinity Capture-MS Homo sapiens
259 SNAI2  
Affinity Capture-Western Homo sapiens
260 KPNA4 3840
Reconstituted Complex Homo sapiens
261 WDR61 80349
Affinity Capture-Western Homo sapiens
262 PLOD2 5352
Co-fractionation Homo sapiens
263 PPIL2  
Affinity Capture-MS Homo sapiens
264 MDM2  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
265 RRM1 6240
Co-fractionation Homo sapiens
266 NTRK1 4914
Affinity Capture-MS Homo sapiens
267 WIPI2 26100
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
268 DNAJA1 3301
Affinity Capture-MS Homo sapiens
269 HUWE1 10075
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
270 RPLP1 6176
Affinity Capture-MS Homo sapiens
271 COPS3 8533
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
272 DCAF4L1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
273 DHX9 1660
Affinity Capture-MS Homo sapiens
274 HNRNPA3 220988
Affinity Capture-MS Homo sapiens
275 REST 5978
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
276 TMCO3 55002
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
277 CLCN1  
Affinity Capture-Western Homo sapiens
278 RPL11 6135
Affinity Capture-MS Homo sapiens
279 LARP1 23367
Affinity Capture-MS Homo sapiens
280 Brwd3  
Affinity Capture-MS Mus musculus
281 HNRNPDL 9987
Affinity Capture-MS Homo sapiens
282 AHCY 191
Affinity Capture-MS Homo sapiens
283 MYCBP2 23077
Affinity Capture-MS Homo sapiens
284 EEF2 1938
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
285 IGHV3OR15-7  
Affinity Capture-MS Homo sapiens
286 RPL14 9045
Affinity Capture-MS Homo sapiens
287 S100A7 6278
Affinity Capture-MS Homo sapiens
288 DCAF13 25879
Affinity Capture-MS Homo sapiens
289 RPL21 6144
Affinity Capture-MS Homo sapiens
290 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
291 DHX30 22907
Affinity Capture-MS Homo sapiens
292 HNRNPUL1 11100
Affinity Capture-MS Homo sapiens
293 MAP3K7  
Affinity Capture-MS Homo sapiens
294 DCAF6 55827
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
295 KIF11 3832
Affinity Capture-MS Homo sapiens
296 RPL7AP27  
Affinity Capture-MS Homo sapiens
297 DCAF8L2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
298 RPS14 6208
Affinity Capture-MS Homo sapiens
299 RPL12 6136
Affinity Capture-MS Homo sapiens
300 DNAJC10 54431
Affinity Capture-MS Homo sapiens
301 ENO2 2026
Affinity Capture-MS Homo sapiens
302 RPL18 6141
Affinity Capture-MS Homo sapiens
303 RBP1 5947
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
304 FBF1  
Affinity Capture-MS Homo sapiens
305 DET1  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
306 RBM4 5936
Affinity Capture-MS Homo sapiens
307 RBBP5 5929
Affinity Capture-Western Homo sapiens
308 CLCN2  
Affinity Capture-Western Homo sapiens
309 UBE2D3 7323
Reconstituted Complex Homo sapiens
310 DZIP3  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
311 POP7  
Co-fractionation Homo sapiens
312 AGL 178
Affinity Capture-MS Homo sapiens
313 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
314 RPS25 6230
Affinity Capture-MS Homo sapiens
315 RPS3 6188
Affinity Capture-MS Homo sapiens
316 JUP 3728
Affinity Capture-MS Homo sapiens
317 TOR1AIP2 163590
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
318 SIN3A  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
319 DDX3X 1654
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
320 KRT10 3858
Affinity Capture-MS Homo sapiens
321 RPA1 6117
Co-fractionation Homo sapiens
322 MEN1 4221
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
323 SNRPA 6626
Affinity Capture-MS Homo sapiens
324 RBMXL2  
Affinity Capture-MS Homo sapiens
325 RPTOR 57521
Affinity Capture-Western Homo sapiens
326 SHFM1 7979
Affinity Capture-MS Homo sapiens
327 PLOD1 5351
Affinity Capture-MS Homo sapiens
328 FAM35A  
Proximity Label-MS Homo sapiens
329 PCNA 5111
Affinity Capture-Western Homo sapiens
330 CD6 923
Affinity Capture-MS Homo sapiens
331 NUDT1  
Affinity Capture-MS Homo sapiens
332 HNRNPH3 3189
Affinity Capture-MS Homo sapiens
333 RTCB 51493
Affinity Capture-MS Homo sapiens
334 FLNA 2316
Affinity Capture-MS Homo sapiens
335 RPS7 6201
Affinity Capture-MS Homo sapiens
336 RPL8 6132
Affinity Capture-MS Homo sapiens
337 HNRNPF 3185
Affinity Capture-MS Homo sapiens
338 C14orf166 51637
Affinity Capture-MS Homo sapiens
339 CCDC80 151887
Affinity Capture-MS Homo sapiens
340 RPL7AP9  
Affinity Capture-MS Homo sapiens
341 COPS4 51138
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
342 NUCKS1 64710
Affinity Capture-MS Homo sapiens
343 DDX56  
Affinity Capture-MS Homo sapiens
344 HIST1H2AE 3012
Affinity Capture-MS Homo sapiens
345 EP300 2033
Affinity Capture-MS Homo sapiens
346 HNRNPA2B1 3181
Affinity Capture-MS Homo sapiens
347 CRBN  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
348 RIT1 6016
Negative Genetic Homo sapiens
349 IGF2BP1 10642
Affinity Capture-MS Homo sapiens
350 DPY19L4  
Affinity Capture-MS Homo sapiens
351 RPL30 6156
Affinity Capture-MS Homo sapiens
352 KPNB1 3837
Reconstituted Complex Homo sapiens
353 HSPA1L 3305
Affinity Capture-MS Homo sapiens
354 RPSAP12 387867
Affinity Capture-MS Homo sapiens
355 RPL15 6138
Affinity Capture-MS Homo sapiens
356 TLE3  
Affinity Capture-MS Homo sapiens
357 MCCC1 56922
Affinity Capture-MS Homo sapiens
358 PPIA 5478
Affinity Capture-MS Homo sapiens
359 CALM1 801
Affinity Capture-MS Homo sapiens
360 SAP30 8819
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
361 SNRPD2 6633
Affinity Capture-MS Homo sapiens
362 APP 351
Reconstituted Complex Homo sapiens
363 BRWD1  
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
364 MYEOV2 150678
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
365 ILF2 3608
Affinity Capture-MS Homo sapiens
366 RPS20 6224
Affinity Capture-MS Homo sapiens
367 PRDX3 10935
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
368 HSPA5 3309
Affinity Capture-MS Homo sapiens
369 TBL1XR1 79718
Affinity Capture-Western Homo sapiens
370 Dtl  
Affinity Capture-MS Mus musculus
Affinity Capture-MS Mus musculus
371 NR2C2  
Affinity Capture-Western Homo sapiens
372 COPS5 10987
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
373 FBXW7  
Affinity Capture-MS Homo sapiens
374 RPL24 6152
Affinity Capture-MS Homo sapiens
375 CALM3 808
Affinity Capture-MS Homo sapiens
376 SNRPC 6631
Affinity Capture-MS Homo sapiens
377 CDT1  
Affinity Capture-Western Homo sapiens
378 CDCA8 55143
Affinity Capture-MS Homo sapiens
379 MYCN  
Affinity Capture-MS Homo sapiens
380 FBXW5  
Affinity Capture-MS Homo sapiens
381 RBBP7 5931
Affinity Capture-Western Homo sapiens
382 RORC 6097
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
383 TXN 7295
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
384 SMU1 55234
Affinity Capture-MS Homo sapiens
385 DCUN1D5 84259
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
386 DDX5 1655
Affinity Capture-MS Homo sapiens
387 KRT75 9119
Affinity Capture-MS Homo sapiens
388 SF3B6 51639
Cross-Linking-MS (XL-MS) Homo sapiens
389 RPL27A 6157
Affinity Capture-MS Homo sapiens
390 GANAB 23193
Affinity Capture-MS Homo sapiens
391 DDX1 1653
Affinity Capture-MS Homo sapiens
392 KRT2 3849
Affinity Capture-MS Homo sapiens
393 SUDS3  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
394 MBD3 53615
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
395 COG4 25839
Affinity Capture-MS Homo sapiens
396 HIST1H2AB 8335
Affinity Capture-MS Homo sapiens
397 BAG3 9531
Affinity Capture-MS Homo sapiens
398 WDR82 80335
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
399 SFPQ 6421
Affinity Capture-MS Homo sapiens
400 BPLF1  
Affinity Capture-Western
Affinity Capture-Western
401 COPS2 9318
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
402 RPLP2 6181
Affinity Capture-MS Homo sapiens
403 CUL3 8452
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
404 RPL7A 6130
Affinity Capture-MS Homo sapiens
405 TLE2  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
406 APAF1 317
Affinity Capture-Western Homo sapiens
407 EIF4G1 1981
Affinity Capture-MS Homo sapiens
408 RPL35 11224
Affinity Capture-MS Homo sapiens
409 SRSF1 6426
Affinity Capture-MS Homo sapiens
410 DDB2  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
411 COPS8 10920
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
412 ERCC8  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
413 RPS8 6202
Affinity Capture-MS Homo sapiens
414 CCNE1  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
415 RPL3 6122
Affinity Capture-MS Homo sapiens
416 DCUN1D2 55208
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
417 NAP1L1 4673
Affinity Capture-MS Homo sapiens
418 RPL7 6129
Affinity Capture-MS Homo sapiens
419 NXF1 10482
Co-fractionation Homo sapiens
420 DCUN1D1 54165
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
421 RPS26P54  
Affinity Capture-MS Homo sapiens
422 DCUN1D4  
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
423 TRIM27  
Affinity Capture-MS Homo sapiens
424 NFKB1 4790
Affinity Capture-MS Homo sapiens
425 CCNG1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
426 DCUN1D3 123879
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
427 Xbp1  
Affinity Capture-Western Mus musculus
428 KRT16 3868
Affinity Capture-MS Homo sapiens
429 DOCK9 23348
Affinity Capture-MS Homo sapiens
430 DHX15 1665
Affinity Capture-MS Homo sapiens
431 SALL2  
Reconstituted Complex Homo sapiens
432 SNAI1  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
433 SAP130  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
434 TUBG1 7283
Affinity Capture-Western Homo sapiens
435 ERH 2079
Affinity Capture-MS Homo sapiens
436 UVSSA  
Affinity Capture-MS Homo sapiens
437 SAP18 10284
Affinity Capture-Western Homo sapiens
438 CUL5 8065
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
439 EIF5A2 56648
Affinity Capture-MS Homo sapiens
440 ELAVL1 1994
Affinity Capture-MS Homo sapiens
441 DCAF11  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
442 HDAC1 3065
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Co-localization Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Co-localization Homo sapiens
443 KRT71 112802
Affinity Capture-MS Homo sapiens
444 TUBB1 81027
Affinity Capture-MS Homo sapiens
445 RNF7  
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
446 SNRNP40 9410
Affinity Capture-Western Homo sapiens
447 HIST1H2AK 8330
Affinity Capture-MS Homo sapiens
448 SRSF7 6432
Affinity Capture-MS Homo sapiens
449 RPS6 6194
Affinity Capture-MS Homo sapiens
450 WDR5B  
Affinity Capture-Western Homo sapiens
451 SRM 6723
Co-fractionation Homo sapiens
452 WARS 7453
Co-fractionation Homo sapiens
453 ZMAT4  
Two-hybrid Homo sapiens
454 RPA3 6119
Proximity Label-MS Homo sapiens
455 GAPDH 2597
Affinity Capture-MS Homo sapiens
456 WDHD1  
Affinity Capture-Western Homo sapiens
457 DCAF5  
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
458 NEDD8 4738
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
459 ALDOA 226
Affinity Capture-MS Homo sapiens
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Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here