Experiment description of studies that identified TMCO3 in exosomes

1 Experiment ID 235 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N Journal name Carcinogenesis Publication year 2015 Sample Hepatocellular carcinoma cells Sample name HKCI-8 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RT-PCR RNA Sequencing

2 Experiment ID 237 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N Journal name Carcinogenesis Publication year 2015 Sample Hepatocytes Sample name MIHA Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RNA Sequencing

Protein-protein interactions for TMCO3

Protein Interactor ExoCarta ID Identification method PubMed Species 1 ATP13A2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 2 PSME2 5721 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 3 TMEM259 91304 Affinity Capture-MS Homo sapiens 4 AGPAT5 55326 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 5 DPH6   Affinity Capture-MS Homo sapiens 6 TMBIM6 7009 Affinity Capture-MS Homo sapiens 7 SLC25A6 293 Affinity Capture-MS Homo sapiens 8 SERPINA12   Affinity Capture-MS Homo sapiens 9 DNAJA3 9093 Affinity Capture-MS Homo sapiens 10 GGCX 2677 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 11 CTSV 1515 Affinity Capture-MS Homo sapiens 12 ATG9A 79065 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 13 METTL13 51603 Affinity Capture-MS Homo sapiens 14 PXMP2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 15 TSHR 7253 Two-hybrid Homo sapiens 16 SLC26A6 65010 Affinity Capture-MS Homo sapiens 17 GLP1R   PCA Homo sapiens 18 TUBB8 347688 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 19 IFT57 55081 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 20 DNAAF5 54919 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 21 TUBB3 10381 Affinity Capture-MS Homo sapiens 22 NIPAL1   Affinity Capture-MS Homo sapiens 23 ELAVL1 1994 Affinity Capture-RNA Homo sapiens 24 CUL4B 8450 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 25 FFAR1   Affinity Capture-MS Homo sapiens 26 FADS1 3992 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 27 FNDC5   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 28 SDR9C7   Affinity Capture-MS Homo sapiens 29 POTEF 728378 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 30 DCAF8 50717 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 31 GUF1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 32 TUBA4A 7277 Affinity Capture-MS Homo sapiens 33 FPR2   Affinity Capture-MS Homo sapiens 34 TSPAN8 7103 Affinity Capture-MS Homo sapiens 35 BRI3BP 140707 Affinity Capture-MS Homo sapiens 36 SREBF2 6721 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 37 TYK2 7297 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 38 EGFR 1956 PCA Homo sapiens 39 ATP13A3 79572 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 40 LAMB3 3914 Affinity Capture-MS Homo sapiens 41 TPST2 8459 Affinity Capture-MS Homo sapiens 42 TAP2 6891 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 43 SLC25A17 10478 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 44 HEMK1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 45 HSPB1 3315 Two-hybrid Homo sapiens 46 SQLE 6713 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 47 ADCK2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 48 STX17 55014 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 49 COG4 25839 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 50 CUL4A 8451 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 51 PIGQ   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 52 KPRP 448834 Affinity Capture-MS Homo sapiens View the network

Pathways in which TMCO3 is involved

No pathways found