Gene description for METTL13
Gene name methyltransferase like 13
Gene symbol METTL13
Other names/aliases 5630401D24Rik
CGI-01
KIAA0859
feat
Species Homo sapiens
 Database cross references - METTL13
ExoCarta ExoCarta_51603
Vesiclepedia VP_51603
Entrez Gene 51603
HGNC 24248
UniProt Q8N6R0  
 METTL13 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells 36408942    
Thymus 23844026    
 Gene ontology annotations for METTL13
Molecular Function
    protein binding GO:0005515 IPI
    protein-lysine N-methyltransferase activity GO:0016279 IDA
Biological Process
    methylation GO:0032259 IEA
Subcellular Localization
    nucleus GO:0005634 ISS
    cytoplasm GO:0005737 ISS
    mitochondrion GO:0005739 ISS
    cytosol GO:0005829 IDA
 Experiment description of studies that identified METTL13 in exosomes
1
Experiment ID 488
MISEV standards
EM
Biophysical techniques
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 217
MISEV standards
EM
Biophysical techniques
TSG101|CD81|CD9|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for METTL13
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Ppp2r1a 51792
Affinity Capture-MS Mus musculus
2 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
3 PTPRF 5792
Co-fractionation Homo sapiens
4 GIPC1 10755
Co-fractionation Homo sapiens
5 SERPINB4 6318
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 APLNR  
Affinity Capture-MS Homo sapiens
7 DNAJC8 22826
Co-fractionation Homo sapiens
8 NTMT1 28989
Co-fractionation Homo sapiens
9 FAM167A  
Affinity Capture-MS Homo sapiens
10 KLK5 25818
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 FAS 355
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
12 HLA-E 3133
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
13 VPS52 6293
Two-hybrid Homo sapiens
14 LRRC25  
Affinity Capture-MS Homo sapiens
15 EFNA2  
Affinity Capture-MS Homo sapiens
16 SMARCC1 6599
Co-fractionation Homo sapiens
17 TRIM66  
Affinity Capture-MS Homo sapiens
18 CD70 970
Affinity Capture-MS Homo sapiens
19 OPALIN  
Affinity Capture-MS Homo sapiens
20 SNRPA 6626
Two-hybrid Homo sapiens
21 LMNA 4000
Proximity Label-MS Homo sapiens
22 CUL3 8452
Affinity Capture-MS Homo sapiens
23 SIGLEC5  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
24 PTPN2 5771
Co-fractionation Homo sapiens
25 METTL21B  
Affinity Capture-MS Homo sapiens
26 BUB3 9184
Co-fractionation Homo sapiens
27 DDX58 23586
Affinity Capture-RNA Homo sapiens
28 MKI67  
Affinity Capture-MS Homo sapiens
29 THAP1  
Two-hybrid Homo sapiens
30 PFKP 5214
Co-fractionation Homo sapiens
31 MAPK6  
Affinity Capture-MS Homo sapiens
32 CDK20  
Affinity Capture-MS Homo sapiens
33 ANKMY2 57037
Co-fractionation Homo sapiens
34 MYC  
Affinity Capture-MS Homo sapiens
35 Klhl21  
Affinity Capture-MS Mus musculus
36 TBC1D22A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
37 NTRK1 4914
Affinity Capture-MS Homo sapiens
38 GPR45  
Affinity Capture-MS Homo sapiens
39 SKIV2L2 23517
Co-fractionation Homo sapiens
40 SPRTN  
Affinity Capture-MS Homo sapiens
41 GPR182  
Affinity Capture-MS Homo sapiens
42 SYNCRIP 10492
Co-fractionation Homo sapiens
43 FAM174A 345757
Affinity Capture-MS Homo sapiens
44 THBS3 7059
Affinity Capture-MS Homo sapiens
45 BRD1 23774
Affinity Capture-MS Homo sapiens
46 LAMP3  
Affinity Capture-MS Homo sapiens
47 KIF11 3832
Affinity Capture-MS Homo sapiens
48 SNW1 22938
Affinity Capture-MS Homo sapiens
49 DDRGK1 65992
Affinity Capture-MS Homo sapiens
50 DTWD2  
Affinity Capture-MS Homo sapiens
51 AR 367
Affinity Capture-MS Homo sapiens
52 AGK 55750
Affinity Capture-MS Homo sapiens
53 EFNB2 1948
Affinity Capture-MS Homo sapiens
54 C9orf72  
Affinity Capture-MS Homo sapiens
55 TMCO3 55002
Affinity Capture-MS Homo sapiens
56 FOXS1  
Affinity Capture-MS Homo sapiens
57 CACNG4  
Affinity Capture-MS Homo sapiens
58 PIN4 5303
Co-fractionation Homo sapiens
View the network image/svg+xml
 Pathways in which METTL13 is involved
No pathways found





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