Experiment description of studies that identified SERPINB4 in exosomes

1 Experiment ID 231 MISEV standards ✘ Biophysical techniques ✔ Alix|CD63|CD9 Enriched markers ✘ Negative markers ✔ NTA Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25332113     Organism Homo sapiens Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G." Journal name Transfusion Publication year 2015 Sample Platelets Sample name PL-Exs - Rep 1 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Optiprep density gradient Flotation density 1.12-1.15 g/mL Molecules identified in the study Protein Lipids Methods used in the study Western blotting Mass spectrometry

2 Experiment ID 232 MISEV standards ✘ Biophysical techniques ✘ Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25332113     Organism Homo sapiens Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G." Journal name Transfusion Publication year 2015 Sample Platelets Sample name PL-Exs - Rep 2 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Optiprep density gradient Flotation density 1.12-1.15 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry

3 Experiment ID 233 MISEV standards ✘ Biophysical techniques ✘ Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25332113     Organism Homo sapiens Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G." Journal name Transfusion Publication year 2015 Sample Platelets Sample name PL-Exs - Rep 3 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Optiprep density gradient Flotation density 1.12-1.15 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry

4 Experiment ID 63 MISEV standards ✘ Biophysical techniques ✔ AQP2 Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 19056867     Organism Homo sapiens Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes. Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA" Journal name JASN Publication year 2009 Sample Urine Sample name Urine - Normal Isolation/purification methods Differential centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] Western blotting

5 Experiment ID 113 MISEV standards ✔ EM|IEM Biophysical techniques ✔ AQP2 Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 21557262     Organism Homo sapiens Experiment description Proteomic identification of exosomal LRG1: A potential urinary biomarker for detecting NSCLC. Authors "Li Y, Zhang Y, Qiu F, Qiu Z." Journal name ELEC Publication year 2011 Sample Urine Sample name Urine - Normal Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting

Protein-protein interactions for SERPINB4

Protein Interactor ExoCarta ID Identification method PubMed Species 1 CCDC94   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 2 BPHL 670 Affinity Capture-MS Homo sapiens 3 FMOD 2331 Affinity Capture-MS Homo sapiens 4 SPTB 6710 Affinity Capture-MS Homo sapiens 5 NRSN1   Affinity Capture-MS Homo sapiens 6 SKI 6497 Affinity Capture-MS Homo sapiens 7 ANKK1   Affinity Capture-MS Homo sapiens 8 RTCA 8634 Affinity Capture-MS Homo sapiens 9 RNF25 64320 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 10 S100A7 6278 Affinity Capture-MS Homo sapiens 11 ZNF354C   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 12 EBF2   Affinity Capture-MS Homo sapiens 13 ZIC1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 14 MED24 9862 Affinity Capture-MS Homo sapiens 15 PLAC8L1   Affinity Capture-MS Homo sapiens 16 ZNF674 641339 Affinity Capture-MS Homo sapiens 17 ST7   Affinity Capture-MS Homo sapiens 18 CCDC92   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 19 ST6GALNAC6 30815 Affinity Capture-MS Homo sapiens 20 FNDC5   Affinity Capture-MS Homo sapiens 21 COPS5 10987 Affinity Capture-MS Homo sapiens 22 DPPA4   Affinity Capture-MS Homo sapiens 23 L2HGDH   Affinity Capture-MS Homo sapiens 24 ZDHHC6   Affinity Capture-MS Homo sapiens 25 NUDT3 11165 Affinity Capture-MS Homo sapiens 26 GRK4   Affinity Capture-MS Homo sapiens 27 POLL   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 28 POU3F3   Affinity Capture-MS Homo sapiens 29 OR13C3   Affinity Capture-MS Homo sapiens 30 UGT1A10   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 31 FMNL2 114793 Affinity Capture-MS Homo sapiens 32 CYP3A5   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 33 USF2 7392 Affinity Capture-MS Homo sapiens 34 THAP10   Affinity Capture-MS Homo sapiens 35 MRPL39 54148 Affinity Capture-MS Homo sapiens 36 PHF11 51131 Affinity Capture-MS Homo sapiens 37 ZSCAN20   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 38 GPN1   Affinity Capture-MS Homo sapiens 39 BTRC 8945 Affinity Capture-MS Homo sapiens 40 KLHL11   Affinity Capture-MS Homo sapiens 41 AGPAT1 10554 Affinity Capture-MS Homo sapiens 42 C18orf21   Affinity Capture-MS Homo sapiens 43 NDUFS5 4725 Affinity Capture-MS Homo sapiens 44 GSK3B 2932 Affinity Capture-MS Homo sapiens 45 ZFAND4   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 46 METTL13 51603 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 47 DDX19B 11269 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 48 MRPL38   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 49 ZNF550   Affinity Capture-MS Homo sapiens 50 SLC37A4 2542 Affinity Capture-MS Homo sapiens 51 CX3CL1   Affinity Capture-MS Homo sapiens 52 C16orf70   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 53 LRRC10   Affinity Capture-MS Homo sapiens 54 FUNDC2 65991 Affinity Capture-MS Homo sapiens 55 MYCBPAP 84073 Affinity Capture-MS Homo sapiens 56 CERS3   Affinity Capture-MS Homo sapiens 57 RNF115   Affinity Capture-MS Homo sapiens 58 GBAP1   Affinity Capture-MS Homo sapiens 59 SRRT 51593 Affinity Capture-MS Homo sapiens 60 ASCL1   Affinity Capture-MS Homo sapiens 61 UBAC2 337867 Affinity Capture-MS Homo sapiens 62 PDILT   Affinity Capture-MS Homo sapiens 63 RASSF9   Affinity Capture-MS Homo sapiens 64 UPRT 139596 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 65 SFMBT1 51460 Affinity Capture-MS Homo sapiens 66 SREBF2 6721 Positive Genetic Homo sapiens 67 ESRRB   Affinity Capture-MS Homo sapiens 68 LRRN3   Affinity Capture-MS Homo sapiens 69 SARAF   Affinity Capture-MS Homo sapiens 70 PIGT 51604 Affinity Capture-MS Homo sapiens 71 S100A8 6279 Affinity Capture-MS Homo sapiens 72 SLX4   Affinity Capture-MS Homo sapiens 73 SPRR2D   Affinity Capture-MS Homo sapiens 74 SSUH2   Affinity Capture-MS Homo sapiens 75 MBD4   Affinity Capture-MS Homo sapiens 76 HCN1   Affinity Capture-MS Homo sapiens 77 CUL2 8453 Affinity Capture-MS Homo sapiens 78 UPK1A 11045 Affinity Capture-MS Homo sapiens 79 DKK2   Affinity Capture-MS Homo sapiens 80 TRIM21 6737 Affinity Capture-MS Homo sapiens 81 CHMP3 51652 Affinity Capture-MS Homo sapiens 82 RHBDD1 84236 Affinity Capture-MS Homo sapiens 83 SERPINB3 6317 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 84 PPP2R2B 5521 Affinity Capture-MS Homo sapiens 85 DESI1   Affinity Capture-MS Homo sapiens 86 NDST2   Affinity Capture-MS Homo sapiens 87 FANCD2   Affinity Capture-MS Homo sapiens 88 AIFM1 9131 Affinity Capture-MS Homo sapiens 89 CCNC   Affinity Capture-MS Homo sapiens 90 ZFPL1 7542 Affinity Capture-MS Homo sapiens 91 PPM1E   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 92 CCNYL1 151195 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 93 ASCC1 51008 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 94 FAM60A   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 95 TBC1D22B   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 96 ITLN2   Affinity Capture-MS Homo sapiens 97 NPTN 27020 Affinity Capture-MS Homo sapiens 98 MOGAT3   Affinity Capture-MS Homo sapiens 99 UCP2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 100 ATP6AP2 10159 Affinity Capture-MS Homo sapiens 101 PKD2L2 27039 Affinity Capture-MS Homo sapiens 102 NPPA   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 103 PDIA3 2923 Affinity Capture-MS Homo sapiens 104 EGFR 1956 Affinity Capture-MS Homo sapiens 105 ELAC2 60528 Affinity Capture-MS Homo sapiens 106 FTH1 2495 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 107 LGALS7 3963 Affinity Capture-MS Homo sapiens 108 SUSD3 203328 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 109 CTSG 1511 Reconstituted Complex Homo sapiens 110 MAPK6   Affinity Capture-MS Homo sapiens 111 FRMD1   Affinity Capture-MS Homo sapiens 112 RPS2P32   Affinity Capture-MS Homo sapiens 113 H2AFB1   Affinity Capture-MS Homo sapiens 114 ITGA9 3680 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 115 COA5   Affinity Capture-MS Homo sapiens 116 EEF1A2 1917 Affinity Capture-MS Homo sapiens 117 ACAD9 28976 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 118 SLC25A6 293 Affinity Capture-MS Homo sapiens 119 MPI 4351 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 120 FCRL5   Affinity Capture-MS Homo sapiens 121 MMRN1 22915 Affinity Capture-MS Homo sapiens 122 STX17 55014 Affinity Capture-MS Homo sapiens 123 PFDN5 5204 Affinity Capture-MS Homo sapiens 124 RIPPLY3   Affinity Capture-MS Homo sapiens 125 UBE2U   Affinity Capture-MS Homo sapiens 126 RAB11A 8766 Affinity Capture-MS Homo sapiens 127 PRSS16 10279 Affinity Capture-MS Homo sapiens 128 IL18 3606 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 129 STARD13 90627 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 130 DAB2 1601 Affinity Capture-MS Homo sapiens 131 MIP   Affinity Capture-MS Homo sapiens 132 APTX   Affinity Capture-MS Homo sapiens 133 SCGB1D1   Affinity Capture-MS Homo sapiens 134 NMB   Affinity Capture-MS Homo sapiens 135 SH2D3A   Affinity Capture-MS Homo sapiens 136 FLYWCH2   Affinity Capture-MS Homo sapiens 137 CUL5 8065 Affinity Capture-MS Homo sapiens 138 EMC4 51234 Affinity Capture-MS Homo sapiens 139 ZNF154   Affinity Capture-MS Homo sapiens 140 CDK15   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 141 C1orf35   Affinity Capture-MS Homo sapiens 142 SSBP2   Affinity Capture-MS Homo sapiens 143 TREX2   Affinity Capture-MS Homo sapiens 144 PTDSS1 9791 Affinity Capture-MS Homo sapiens 145 FBXO44   Affinity Capture-MS Homo sapiens 146 S100A9 6280 Affinity Capture-MS Homo sapiens 147 SIRT1   Affinity Capture-MS Homo sapiens 148 MKI67   Affinity Capture-MS Homo sapiens 149 HOXD10   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 150 FAM227B   Affinity Capture-MS Homo sapiens 151 ESR1   Affinity Capture-MS Homo sapiens 152 ERCC3   Affinity Capture-MS Homo sapiens 153 MBNL1 4154 Affinity Capture-MS Homo sapiens 154 KIR3DS1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 155 HLA-DPA1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 156 TEFM   Affinity Capture-MS Homo sapiens 157 TSPAN6 7105 Affinity Capture-MS Homo sapiens 158 PINK1   Affinity Capture-MS Homo sapiens 159 GPR18   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 160 GOT1 2805 Affinity Capture-MS Homo sapiens 161 STK11 6794 Affinity Capture-MS Homo sapiens 162 PDE4DIP 9659 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 163 OR2A4 79541 Affinity Capture-MS Homo sapiens 164 INSC   Affinity Capture-MS Homo sapiens 165 GABPA 2551 Affinity Capture-MS Homo sapiens 166 CCR1   Affinity Capture-MS Homo sapiens 167 GUCY1A3   Affinity Capture-MS Homo sapiens 168 PCP4   Affinity Capture-MS Homo sapiens 169 CDK11A 728642 Affinity Capture-MS Homo sapiens View the network

Pathways in which SERPINB4 is involved

No pathways found