Gene description for OR2A4
Gene name olfactory receptor, family 2, subfamily A, member 4
Gene symbol OR2A4
Other names/aliases OR2A10
Species Homo sapiens
 Database cross references - OR2A4
ExoCarta ExoCarta_79541
Vesiclepedia VP_79541
Entrez Gene 79541
HGNC 14729
UniProt O95047  
 OR2A4 identified in exosomes derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for OR2A4
Molecular Function
    G protein-coupled receptor activity GO:0004930 IEA
    olfactory receptor activity GO:0004984 IBA
    odorant binding GO:0005549 IBA
Biological Process
    G protein-coupled receptor signaling pathway GO:0007186 IEA
    positive regulation of cytokinesis GO:0032467 IMP
    regulation of actin cytoskeleton organization GO:0032956 IMP
    detection of chemical stimulus involved in sensory perception of smell GO:0050911 IBA
Subcellular Localization
    membrane GO:0016020 IBA
    cleavage furrow GO:0032154 IDA
    recycling endosome GO:0055037 IDA
    Flemming body GO:0090543 IDA
    mitotic spindle pole GO:0097431 IDA
    mitotic spindle midzone GO:1990023 IDA
 Experiment description of studies that identified OR2A4 in exosomes
1
Experiment ID 63
MISEV standards
Biophysical techniques
AQP2
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for OR2A4
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CAPNS2 84290
Affinity Capture-MS Homo sapiens
2 HMOX1 3162
Affinity Capture-MS Homo sapiens
3 SERPINB4 6318
Affinity Capture-MS Homo sapiens
4 CLIP1 6249
Affinity Capture-MS Homo sapiens
5 AKR1B10 57016
Affinity Capture-MS Homo sapiens
6 DSG1 1828
Affinity Capture-MS Homo sapiens
7 EML2 24139
Affinity Capture-MS Homo sapiens
8 DHRS9  
Affinity Capture-MS Homo sapiens
9 IL36G 56300
Affinity Capture-MS Homo sapiens
10 ANXA8 653145
Affinity Capture-MS Homo sapiens
11 IGHM 3507
Affinity Capture-MS Homo sapiens
12 ACOX1 51
Affinity Capture-MS Homo sapiens
13 IL36RN  
Affinity Capture-MS Homo sapiens
14 UBL3 5412
Affinity Capture-MS Homo sapiens
15 IL36A  
Affinity Capture-MS Homo sapiens
16 GAN 8139
Affinity Capture-MS Homo sapiens
17 ALOX12B  
Affinity Capture-MS Homo sapiens
18 PSMB8 5696
Affinity Capture-MS Homo sapiens
19 HAL 3034
Affinity Capture-MS Homo sapiens
20 PPL 5493
Affinity Capture-MS Homo sapiens
21 NDRG2 57447
Affinity Capture-MS Homo sapiens
22 TSTA3 7264
Affinity Capture-MS Homo sapiens
23 CAPG 822
Affinity Capture-MS Homo sapiens
24 ALDH1A1 216
Affinity Capture-MS Homo sapiens
25 NDRG1 10397
Affinity Capture-MS Homo sapiens
26 C3 718
Affinity Capture-MS Homo sapiens
27 GLRX 2745
Affinity Capture-MS Homo sapiens
28 ACPP 55
Affinity Capture-MS Homo sapiens
29 STAT3 6774
Affinity Capture-MS Homo sapiens
30 CAPN1 823
Affinity Capture-MS Homo sapiens
31 NARS 4677
Affinity Capture-MS Homo sapiens
32 NT5C3A 51251
Affinity Capture-MS Homo sapiens
33 RAB5B 5869
Affinity Capture-MS Homo sapiens
34 FLG 2312
Affinity Capture-MS Homo sapiens
35 CPA4 51200
Affinity Capture-MS Homo sapiens
36 ENDOU  
Affinity Capture-MS Homo sapiens
37 A2M 2
Affinity Capture-MS Homo sapiens
38 NAGK 55577
Affinity Capture-MS Homo sapiens
39 KLK6 5653
Affinity Capture-MS Homo sapiens
40 PAPL  
Affinity Capture-MS Homo sapiens
41 GDA 9615
Affinity Capture-MS Homo sapiens
42 RDH12 145226
Affinity Capture-MS Homo sapiens
43 LCP1 3936
Affinity Capture-MS Homo sapiens
44 POF1B 79983
Affinity Capture-MS Homo sapiens
45 KCTD4  
Affinity Capture-MS Homo sapiens
46 SCEL 8796
Affinity Capture-MS Homo sapiens
47 HMGCS1 3157
Affinity Capture-MS Homo sapiens
48 FGA 2243
Affinity Capture-MS Homo sapiens
49 ACADVL 37
Affinity Capture-MS Homo sapiens
50 SBSN 374897
Affinity Capture-MS Homo sapiens
51 CERS3  
Affinity Capture-MS Homo sapiens
52 SERPINB1 1992
Affinity Capture-MS Homo sapiens
53 PTK6  
Affinity Capture-MS Homo sapiens
54 EPS8L2 64787
Affinity Capture-MS Homo sapiens
55 ARG1 383
Affinity Capture-MS Homo sapiens
56 UBAC2 337867
Affinity Capture-MS Homo sapiens
57 FGG 2266
Affinity Capture-MS Homo sapiens
58 TPRG1  
Affinity Capture-MS Homo sapiens
59 IGHG1 3500
Affinity Capture-MS Homo sapiens
60 SERPINB8 5271
Affinity Capture-MS Homo sapiens
61 S100A8 6279
Affinity Capture-MS Homo sapiens
62 ANXA9  
Affinity Capture-MS Homo sapiens
63 SMPD3  
Affinity Capture-MS Homo sapiens
64 ALDH3A1 218
Affinity Capture-MS Homo sapiens
65 TGM1 7051
Affinity Capture-MS Homo sapiens
66 RAB25 57111
Affinity Capture-MS Homo sapiens
67 SERPINB7 8710
Affinity Capture-MS Homo sapiens
68 LYPLA1 10434
Affinity Capture-MS Homo sapiens
69 CALML5 51806
Affinity Capture-MS Homo sapiens
70 SERPINA3 12
Affinity Capture-MS Homo sapiens
71 H2AFY 9555
Affinity Capture-MS Homo sapiens
72 SERPINB13 5275
Affinity Capture-MS Homo sapiens
73 UPP1 7378
Affinity Capture-MS Homo sapiens
74 SQRDL 58472
Affinity Capture-MS Homo sapiens
75 CALML3 810
Affinity Capture-MS Homo sapiens
76 CASP14 23581
Affinity Capture-MS Homo sapiens
77 S100P 6286
Affinity Capture-MS Homo sapiens
78 FAM129B 64855
Affinity Capture-MS Homo sapiens
79 QSOX1 5768
Affinity Capture-MS Homo sapiens
80 IVL 3713
Affinity Capture-MS Homo sapiens
81 BLVRB 645
Affinity Capture-MS Homo sapiens
82 TYMP 1890
Affinity Capture-MS Homo sapiens
83 HEPHL1  
Affinity Capture-MS Homo sapiens
84 IL1RN 3557
Affinity Capture-MS Homo sapiens
85 ANXA1 301
Affinity Capture-MS Homo sapiens
86 IGKC 3514
Affinity Capture-MS Homo sapiens
87 EPPK1 83481
Affinity Capture-MS Homo sapiens
88 S100A7 6278
Affinity Capture-MS Homo sapiens
89 CYP4F22  
Affinity Capture-MS Homo sapiens
90 S100A7A 338324
Affinity Capture-MS Homo sapiens
91 SERPINB5 5268
Affinity Capture-MS Homo sapiens
92 A2ML1 144568
Affinity Capture-MS Homo sapiens
93 CYB5R2 51700
Affinity Capture-MS Homo sapiens
94 EPS8L1 54869
Affinity Capture-MS Homo sapiens
95 LGALS7B 653499
Affinity Capture-MS Homo sapiens
96 HPGD 3248
Affinity Capture-MS Homo sapiens
97 EVPL 2125
Affinity Capture-MS Homo sapiens
98 HPSE 10855
Affinity Capture-MS Homo sapiens
99 DCX  
Affinity Capture-MS Homo sapiens
100 RBP1 5947
Affinity Capture-MS Homo sapiens
101 SDR9C7  
Affinity Capture-MS Homo sapiens
102 ALDH4A1 8659
Affinity Capture-MS Homo sapiens
103 PKP3 11187
Affinity Capture-MS Homo sapiens
104 TMEM40 55287
Affinity Capture-MS Homo sapiens
105 GSN 2934
Affinity Capture-MS Homo sapiens
106 JMJD7-PLA2G4B  
Affinity Capture-MS Homo sapiens
107 NAPRT 93100
Affinity Capture-MS Homo sapiens
108 RNASE7 84659
Affinity Capture-MS Homo sapiens
109 IGLC6 3542
Affinity Capture-MS Homo sapiens
110 PREP 5550
Affinity Capture-MS Homo sapiens
111 JUP 3728
Affinity Capture-MS Homo sapiens
112 PLEC 5339
Affinity Capture-MS Homo sapiens
113 PYCARD 29108
Affinity Capture-MS Homo sapiens
114 IGLL5 100423062
Affinity Capture-MS Homo sapiens
115 CRABP2 1382
Affinity Capture-MS Homo sapiens
116 ITPKC  
Affinity Capture-MS Homo sapiens
117 OXSR1 9943
Affinity Capture-MS Homo sapiens
118 IGHG2 3501
Affinity Capture-MS Homo sapiens
119 TREX2  
Affinity Capture-MS Homo sapiens
120 FAM83H 286077
Affinity Capture-MS Homo sapiens
121 S100A9 6280
Affinity Capture-MS Homo sapiens
122 PKP1 5317
Affinity Capture-MS Homo sapiens
123 SERPINB3 6317
Affinity Capture-MS Homo sapiens
124 TRIM25 7706
Affinity Capture-MS Homo sapiens
125 IDH2 3418
Affinity Capture-MS Homo sapiens
126 PGM2 55276
Affinity Capture-MS Homo sapiens
127 GLUL 2752
Affinity Capture-MS Homo sapiens
128 KLK10 5655
Affinity Capture-MS Homo sapiens
129 GM2A 2760
Affinity Capture-MS Homo sapiens
130 ME1 4199
Affinity Capture-MS Homo sapiens
131 ZNF185 7739
Affinity Capture-MS Homo sapiens
132 GSDMA 284110
Affinity Capture-MS Homo sapiens
133 PLA2G4D  
Affinity Capture-MS Homo sapiens
134 SERPINB2 5055
Affinity Capture-MS Homo sapiens
135 IGHG3 3502
Affinity Capture-MS Homo sapiens
136 NEU2  
Affinity Capture-MS Homo sapiens
137 ALDH1A3 220
Affinity Capture-MS Homo sapiens
138 LCN2 3934
Affinity Capture-MS Homo sapiens
139 RPL36AL 6166
Affinity Capture-MS Homo sapiens
140 TRIM29 23650
Affinity Capture-MS Homo sapiens
141 ARHGEF10L 55160
Affinity Capture-MS Homo sapiens
142 FCHSD1 89848
Affinity Capture-MS Homo sapiens
143 ARSF 416
Affinity Capture-MS Homo sapiens
144 SULT2B1 6820
Affinity Capture-MS Homo sapiens
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