Gene description for OR2A4
Gene name olfactory receptor, family 2, subfamily A, member 4
Gene symbol OR2A4
Other names/aliases OR2A10
Species Homo sapiens
 Database cross references - OR2A4
ExoCarta ExoCarta_79541
Entrez Gene 79541
HGNC 14729
UniProt O95047  
 OR2A4 identified in exosomes derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for OR2A4
Molecular Function
    olfactory receptor activity GO:0004984 IEA
    molecular_function GO:0003674 ND
    G-protein coupled receptor activity GO:0004930 IEA
    transmembrane signaling receptor activity GO:0004888 IBA
Biological Process
    detection of chemical stimulus involved in sensory perception of smell GO:0050911 IEA
    detection of chemical stimulus involved in sensory perception GO:0050907 IBA
    G-protein coupled receptor signaling pathway GO:0007186 IBA
    regulation of actin cytoskeleton organization GO:0032956 IMP
    positive regulation of cytokinesis GO:0032467 IMP
Subcellular Localization
    recycling endosome GO:0055037 IDA
    mitotic spindle pole GO:0097431 IDA
    Flemming body GO:0090543 IDA
    mitotic spindle midzone GO:1990023 IDA
    integral component of membrane GO:0016021 IBA
    plasma membrane GO:0005886 TAS
    cleavage furrow GO:0032154 IDA
 Experiment description of studies that identified OR2A4 in exosomes
Experiment ID 63
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for OR2A4
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which OR2A4 is involved
Olfactory Signaling Pathway TAS Reactome

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