Gene description for ME1
Gene name	malic enzyme 1, NADP(+)-dependent, cytosolic
Gene symbol	ME1
Other names/aliases	HUMNDME MES
Species	Homo sapiens
Database cross references - ME1
ExoCarta	ExoCarta_4199
Entrez Gene	4199
HGNC	6983
MIM	154250
UniProt	P48163
ME1 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells	Unpublished / Not applicable
Ovarian cancer cells	23333927
Ovarian cancer cells	23333927

Gene ontology annotations for ME1

Molecular Function     manganese ion binding GO:0030145 IDA     oxaloacetate decarboxylase activity GO:0008948 IEA     ADP binding GO:0043531 TAS     malate dehydrogenase (decarboxylating) (NADP+) activity GO:0004473 ISS     malic enzyme activity GO:0004470 IMP     NAD binding GO:0051287 TAS     electron carrier activity GO:0009055 TAS     NADP binding GO:0050661 TAS     malate dehydrogenase (decarboxylating) (NAD+) activity GO:0004471 IEA Biological Process     small molecule metabolic process GO:0044281 TAS     cellular lipid metabolic process GO:0044255 TAS     malate metabolic process GO:0006108 IDA     carbohydrate metabolic process GO:0005975 NAS     oxidation-reduction process GO:0055114 IEA     response to carbohydrate GO:0009743 TAS     NADP biosynthetic process GO:0006741 TAS     protein tetramerization GO:0051262 IEA     regulation of NADP metabolic process GO:1902031 IMP     response to hormone GO:0009725 ISS Subcellular Localization     mitochondrion GO:0005739 IEA     cytosol GO:0005829 TAS