Gene description for PPWD1
Gene name peptidylprolyl isomerase domain and WD repeat containing 1
Gene symbol PPWD1
Other names/aliases -
Species Homo sapiens
 Database cross references - PPWD1
ExoCarta ExoCarta_23398
Vesiclepedia VP_23398
Entrez Gene 23398
HGNC 28954
UniProt Q96BP3  
 PPWD1 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells 36408942    
 Gene ontology annotations for PPWD1
Molecular Function
    peptidyl-prolyl cis-trans isomerase activity GO:0003755 IBA
Biological Process
    protein peptidyl-prolyl isomerization GO:0000413 IBA
    mRNA splicing, via spliceosome GO:0000398 IC
    protein folding GO:0006457 IEA
Subcellular Localization
    nucleoplasm GO:0005654 IDA
    catalytic step 2 spliceosome GO:0071013 IDA
    nucleus GO:0005634 IDA
 Experiment description of studies that identified PPWD1 in exosomes
1
Experiment ID 488
MISEV standards
✔
EM
EV Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
EV Enriched markers
✔
CANX
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for PPWD1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which PPWD1 is involved
No pathways found





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