Gene description for ADRBK1
Gene name	adrenergic, beta, receptor kinase 1
Gene symbol	ADRBK1
Other names/aliases	BARK1 BETA-ARK1 GRK2
Species	Homo sapiens
Database cross references - ADRBK1
ExoCarta	ExoCarta_156
Entrez Gene	156
HGNC	289
MIM	109635
UniProt	P25098
ADRBK1 identified in exosomes derived from the following tissue/cell type
Colorectal cancer cells	23161513
Colorectal cancer cells	23161513
Colorectal cancer cells	23161513
Thymus	23844026

Gene ontology annotations for ADRBK1

Molecular Function     ATP binding GO:0005524 IEA     beta-adrenergic receptor kinase activity GO:0047696 IEA     Edg-2 lysophosphatidic acid receptor binding GO:0031755 IDA     alpha-2A adrenergic receptor binding GO:0031694 ISS     protein binding GO:0005515 IPI     G-protein coupled receptor kinase activity GO:0004703 ISS     protein kinase activity GO:0004672 ISS Biological Process     fibroblast growth factor receptor signaling pathway GO:0008543 TAS     negative regulation of striated muscle contraction GO:0045988 IMP     tachykinin receptor signaling pathway GO:0007217 IDA     signal transduction GO:0007165 TAS     peptidyl-threonine phosphorylation GO:0018107 IEA     epidermal growth factor receptor signaling pathway GO:0007173 TAS     viral genome replication GO:0019079 IMP     desensitization of G-protein coupled receptor protein signaling pathway GO:0002029 ISS     receptor internalization GO:0031623 IDA     innate immune response GO:0045087 TAS     termination of G-protein coupled receptor signaling pathway GO:0038032 IEA     G-protein coupled acetylcholine receptor signaling pathway GO:0007213 ISS     heart development GO:0007507 IEA     cardiac muscle contraction GO:0060048 IMP     positive regulation of catecholamine secretion GO:0033605 ISS     viral entry into host cell GO:0046718 IMP     peptidyl-serine phosphorylation GO:0018105 ISS     activation of phospholipase C activity GO:0007202 TAS     negative regulation of the force of heart contraction by chemical signal GO:0003108 IMP     neurotrophin TRK receptor signaling pathway GO:0048011 TAS Subcellular Localization     cytoplasm GO:0005737 IDA     cytosol GO:0005829 TAS     membrane GO:0016020 ISS     plasma membrane GO:0005886 TAS     primary cilium GO:0072372 TAS