Gene description for MALT1
Gene name	MALT1 paracaspase
Gene symbol	MALT1
Other names/aliases	IMD12 MLT MLT1
Species	Homo sapiens
Database cross references - MALT1
ExoCarta	ExoCarta_10892
Entrez Gene	10892
HGNC	6819
MIM	604860
UniProt	Q9UDY8
MALT1 identified in exosomes derived from the following tissue/cell type
Thymus	23844026

Gene ontology annotations for MALT1

Molecular Function     protein binding GO:0005515 IPI     ubiquitin-protein transferase activity GO:0004842 IDA     signal transducer activity GO:0004871 IMP     kinase activator activity GO:0019209 IMP     cysteine-type endopeptidase activity GO:0004197 NAS     protein self-association GO:0043621 IPI     peptidase activity GO:0008233 IDA     protease binding GO:0002020 IEA Biological Process     activation of NF-kappaB-inducing kinase activity GO:0007250 IMP     Fc-epsilon receptor signaling pathway GO:0038095 TAS     defense response GO:0006952 NAS     protein oligomerization GO:0051259 IDA     protein ubiquitination GO:0016567 IDA     positive regulation of T cell cytokine production GO:0002726 IMP     stimulatory C-type lectin receptor signaling pathway GO:0002223 TAS     proteolysis GO:0006508 IDA     negative regulation of apoptotic process GO:0043066 NAS     response to fungus GO:0009620 IEA     T cell receptor signaling pathway GO:0050852 TAS     positive regulation of T cell activation GO:0050870 IC     B-1 B cell differentiation GO:0001923 IEA     positive regulation of NF-kappaB transcription factor activity GO:0051092 IMP     T cell proliferation GO:0042098 IEA     response to molecule of bacterial origin GO:0002237 IEA     regulation of apoptotic process GO:0042981 IDA     nuclear export GO:0051168 IDA     positive regulation of protein ubiquitination GO:0031398 NAS     positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123 IMP     innate immune response GO:0045087 TAS     regulation of T cell receptor signaling pathway GO:0050856 IEA     positive regulation of interleukin-2 production GO:0032743 IMP Subcellular Localization     cytosol GO:0005829 TAS     perinuclear region of cytoplasm GO:0048471 IEA     nucleus GO:0005634 IDA     protein complex GO:0043234 IDA     nucleolus GO:0005730 IDA     plasma membrane GO:0005886 TAS     cytoplasm GO:0005737 IDA     CBM complex GO:0032449 NAS