Gene description for CAMK2G
Gene name calcium/calmodulin-dependent protein kinase II gamma
Gene symbol CAMK2G
Other names/aliases CAMK
CAMK-II
CAMKG
Species Homo sapiens
 Database cross references - CAMK2G
ExoCarta ExoCarta_818
Entrez Gene 818
HGNC 1463
MIM 602123
UniProt Q13555  
 CAMK2G identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
Thymus 23844026    
 Gene ontology annotations for CAMK2G
Molecular Function
    calmodulin binding GO:0005516 NAS
    ATP binding GO:0005524 IEA
    calcium-dependent protein serine/threonine phosphatase activity GO:0004723 NAS
    protein binding GO:0005515 IPI
    protein homodimerization activity GO:0042803 IPI
    calmodulin-dependent protein kinase activity GO:0004683 IEA
Biological Process
    regulation of calcium ion transport GO:0051924 TAS
    synaptic transmission GO:0007268 TAS
    calcium ion transport GO:0006816 IEA
    insulin secretion GO:0030073 NAS
    regulation of relaxation of cardiac muscle GO:1901897 IEA
    cytokine-mediated signaling pathway GO:0019221 TAS
    protein oligomerization GO:0051259 IDA
    interferon-gamma-mediated signaling pathway GO:0060333 TAS
    regulation of skeletal muscle adaptation GO:0014733 TAS
    cellular response to heat GO:0034605 TAS
    dephosphorylation GO:0016311 NAS
    protein autophosphorylation GO:0046777 IEA
    regulation of cellular response to heat GO:1900034 TAS
    cell differentiation GO:0030154 IEA
    nervous system development GO:0007399 IEA
    G1/S transition of mitotic cell cycle GO:0000082 IEA
Subcellular Localization
    cytosol GO:0005829 TAS
    nucleoplasm GO:0005654 TAS
    plasma membrane GO:0005886 TAS
    membrane GO:0016020 IDA
    sarcoplasmic reticulum membrane GO:0033017 IEA
    endocytic vesicle membrane GO:0030666 TAS
 Experiment description of studies that identified CAMK2G in exosomes
1
Experiment ID 237
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
2
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for CAMK2G
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 STAT1 6772
Invivo Homo sapiens
Invitro Homo sapiens
2 SMAD2 4087
Biochemical Activity Homo sapiens
3 RRAD  
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
4 CABP2  
Invivo Homo sapiens
Invivo Homo sapiens
Invitro Homo sapiens
Invitro Homo sapiens
5 TIAM1  
Invivo Homo sapiens
Invitro Homo sapiens
6 SMAD4  
Biochemical Activity Homo sapiens
7 CALM1 801
Reconstituted Complex Homo sapiens
8 ACTN4 81
Invivo Homo sapiens
Invitro Homo sapiens
Two-hybrid Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here