Gene description for THOC2
Gene name THO complex 2
Gene symbol THOC2
Other names/aliases CXorf3
THO2
dJ506G2.1
hTREX120
Species Homo sapiens
 Database cross references - THOC2
ExoCarta ExoCarta_57187
Entrez Gene 57187
HGNC 19073
MIM 300395
UniProt Q8NI27  
 THOC2 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for THOC2
Molecular Function
    RNA binding GO:0003723 IEA
    protein binding GO:0005515 IPI
Biological Process
    mRNA processing GO:0006397 IEA
    RNA splicing GO:0008380 IEA
    viral mRNA export from host cell nucleus GO:0046784 IDA
    mRNA export from nucleus GO:0006406 IDA
    poly(A)+ mRNA export from nucleus GO:0016973 IDA
Subcellular Localization
    transcription export complex GO:0000346 IDA
    THO complex part of transcription export complex GO:0000445 IDA
    nuclear speck GO:0016607 IEA
    THO complex GO:0000347 IDA
    nucleoplasm GO:0005654 IDA
 Experiment description of studies that identified THOC2 in exosomes
1
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for THOC2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 THOC1 9984
Invitro Homo sapiens
2 ALYREF 10189
Invitro Homo sapiens
View the network image/svg+xml
 Pathways in which THOC2 is involved
No pathways found





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