Gene description for ALYREF
Gene name Aly/REF export factor
Gene symbol ALYREF
Other names/aliases ALY
ALY/REF
BEF
REF
THOC4
Species Homo sapiens
 Database cross references - ALYREF
ExoCarta ExoCarta_10189
Vesiclepedia VP_10189
Entrez Gene 10189
HGNC 19071
MIM 604171
UniProt Q86V81  
 ALYREF identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
T lymphocytes 34108659    
Urine 19056867    
 Gene ontology annotations for ALYREF
Molecular Function
    RNA binding GO:0003723 HDA
    mRNA binding GO:0003729 IBA
    protein binding GO:0005515 IPI
    C5-methylcytidine-containing RNA reader activity GO:0062153 IDA
Biological Process
    osteoblast differentiation GO:0001649 HDA
    mRNA processing GO:0006397 IEA
    RNA export from nucleus GO:0006405 IDA
    mRNA export from nucleus GO:0006406 IBA
    mRNA export from nucleus GO:0006406 IMP
    RNA splicing GO:0008380 IEA
Subcellular Localization
    transcription export complex GO:0000346 IDA
    chromosome, telomeric region GO:0000781 IDA
    nucleus GO:0005634 IBA
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 TAS
    cytoplasm GO:0005737 IDA
    cytosol GO:0005829 TAS
    membrane GO:0016020 HDA
    nuclear speck GO:0016607 IEA
    exon-exon junction complex GO:0035145 IDA
    extracellular exosome GO:0070062 HDA
    catalytic step 2 spliceosome GO:0071013 IDA
 Experiment description of studies that identified ALYREF in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
10
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
11
Experiment ID 207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
12
Experiment ID 208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
15
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
16
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
17
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
18
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
19
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
20
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
21
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
22
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
23
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
24
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
25
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
26
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
27
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
28
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
29
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
30
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
31
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
32
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
33
Experiment ID 63
MISEV standards
✘ Biophysical techniques
✔
AQP2
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for ALYREF
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CD3EAP  
Co-fractionation Homo sapiens
2 SNRPA 6626
Affinity Capture-MS Homo sapiens
3 RIT1 6016
Negative Genetic Homo sapiens
4 UBE2H 7328
Affinity Capture-MS Homo sapiens
5 LUZP4  
Affinity Capture-MS Homo sapiens
6 METTL17  
Proximity Label-MS Homo sapiens
7 RPL26L1 51121
Affinity Capture-MS Homo sapiens
8 NCBP1 4686
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
9 JMJD1C 221037
Cross-Linking-MS (XL-MS) Homo sapiens
10 PAXIP1  
Affinity Capture-MS Homo sapiens
11 SKIV2L 6499
Co-fractionation Homo sapiens
12 PCF11 51585
Affinity Capture-Western Homo sapiens
13 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
14 RIN3  
Affinity Capture-MS Homo sapiens
15 TNPO1 3842
Affinity Capture-MS Homo sapiens
16 RBM15B  
Affinity Capture-Western Homo sapiens
17 RPA2 6118
Proximity Label-MS Homo sapiens
18 HIST1H2BG 8339
Proximity Label-MS Homo sapiens
19 THOC2 57187
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
20 BRCA1 672
Affinity Capture-RNA Homo sapiens
21 MTG2  
Proximity Label-MS Homo sapiens
22 RPL10 6134
Affinity Capture-MS Homo sapiens
23 KIF20A 10112
Affinity Capture-MS Homo sapiens
24 LSM4 25804
Affinity Capture-MS Homo sapiens
25 TLE3  
Co-fractionation Homo sapiens
26 UBC 7316
Affinity Capture-MS Homo sapiens
27 THOC7 80145
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
28 PRPF3  
Affinity Capture-MS Homo sapiens
29 CAND1 55832
Affinity Capture-MS Homo sapiens
30 RNF40 9810
Affinity Capture-MS Homo sapiens
31 SRSF2 6427
Affinity Capture-MS Homo sapiens
32 PARK7 11315
Affinity Capture-MS Homo sapiens
33 SNRPF 6636
Affinity Capture-MS Homo sapiens
34 SOX2  
Affinity Capture-MS Homo sapiens
35 FAU 2197
Affinity Capture-MS Homo sapiens
36 CENPA  
Proximity Label-MS Homo sapiens
37 ATG13 9776
Affinity Capture-MS Homo sapiens
38 KIAA1429 25962
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
39 Rrp1b 72462
Affinity Capture-MS Mus musculus
40 CAPZB 832
Affinity Capture-MS Homo sapiens
41 DDX23 9416
Proximity Label-MS Homo sapiens
42 DYNC1H1 1778
Cross-Linking-MS (XL-MS) Homo sapiens
43 ACAD9 28976
Proximity Label-MS Homo sapiens
44 ZBTB2 57621
Affinity Capture-MS Homo sapiens
45 KIF23 9493
Affinity Capture-MS Homo sapiens
46 SF3B1 23451
Affinity Capture-MS Homo sapiens
47 CHCHD2  
Affinity Capture-MS Homo sapiens
48 PRMT5 10419
Affinity Capture-MS Homo sapiens
49 COPS5 10987
Affinity Capture-MS Homo sapiens
50 FBXW7  
Affinity Capture-MS Homo sapiens
51 PRC1 9055
Affinity Capture-MS Homo sapiens
52 IQGAP1 8826
Affinity Capture-MS Homo sapiens
53 SRRM2 23524
Co-fractionation Homo sapiens
54 SNRPC 6631
Affinity Capture-MS Homo sapiens
55 CBX1 10951
Cross-Linking-MS (XL-MS) Homo sapiens
56 OBSL1 23363
Affinity Capture-MS Homo sapiens
57 SF3A2 8175
Affinity Capture-MS Homo sapiens
58 MYCN  
Affinity Capture-MS Homo sapiens
59 CLNS1A 1207
Affinity Capture-MS Homo sapiens
60 EXD2  
Proximity Label-MS Homo sapiens
61 ITGA4 3676
Affinity Capture-MS Homo sapiens
62 EED  
Affinity Capture-MS Homo sapiens
63 THOC6 79228
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
64 VCAM1 7412
Affinity Capture-MS Homo sapiens
65 CUL1 8454
Affinity Capture-MS Homo sapiens
66 ARIH2 10425
Affinity Capture-MS Homo sapiens
67 TACO1  
Proximity Label-MS Homo sapiens
68 THOC1 9984
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
69 MRPL11 65003
Proximity Label-MS Homo sapiens
70 Erh  
Affinity Capture-MS Mus musculus
71 PABPC4 8761
Co-fractionation Homo sapiens
72 HSD17B10 3028
Affinity Capture-MS Homo sapiens
73 MTERF3  
Proximity Label-MS Homo sapiens
74 RBM8A 9939
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
75 KIF14 9928
Affinity Capture-MS Homo sapiens
76 TRIP12 9320
Co-fractionation Homo sapiens
77 PRNP 5621
Affinity Capture-MS Homo sapiens
78 FOXP1 27086
Protein-RNA Homo sapiens
79 EMC9  
Affinity Capture-MS Homo sapiens
80 MDH2 4191
Proximity Label-MS Homo sapiens
81 HSPA9 3313
Co-fractionation Homo sapiens
82 UGGT1 56886
Co-fractionation Homo sapiens
83 VRK3 51231
Affinity Capture-Western Homo sapiens
84 NOP2 4839
Co-fractionation Homo sapiens
85 C6orf203  
Proximity Label-MS Homo sapiens
86 COX15 1355
Affinity Capture-MS Homo sapiens
87 DDX21 9188
Affinity Capture-MS Homo sapiens
88 SRRM1 10250
Affinity Capture-MS Homo sapiens
89 MEPCE 56257
Affinity Capture-MS Homo sapiens
90 WHSC1 7468
Proximity Label-MS Homo sapiens
91 DLGAP4 22839
Affinity Capture-MS Homo sapiens
92 C17orf85  
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
93 XRN1 54464
Co-fractionation Homo sapiens
94 DOT1L 84444
Affinity Capture-MS Homo sapiens
95 STAU1 6780
Affinity Capture-MS Homo sapiens
96 ACIN1 22985
Affinity Capture-MS Homo sapiens
97 SRRT 51593
Affinity Capture-MS Homo sapiens
98 PPIH 10465
Affinity Capture-MS Homo sapiens
99 VRK1 7443
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
100 UBE2I 7329
Co-fractionation Homo sapiens
101 DEK 7913
Co-fractionation Homo sapiens
102 MKRN2 23609
Affinity Capture-MS Homo sapiens
103 CHMP4B 128866
Affinity Capture-MS Homo sapiens
104 TYK2 7297
Affinity Capture-MS Homo sapiens
105 NTRK1 4914
Affinity Capture-MS Homo sapiens
106 PABPC1 26986
Co-fractionation Homo sapiens
107 U2AF2 11338
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
108 RAD18  
Affinity Capture-MS Homo sapiens
109 CSNK1E 1454
Co-fractionation Homo sapiens
110 DHX9 1660
Co-fractionation Homo sapiens
111 HECTD1 25831
Affinity Capture-MS Homo sapiens
112 MAGOH 4116
Affinity Capture-MS Homo sapiens
113 CUL2 8453
Affinity Capture-MS Homo sapiens
114 RRP1B 23076
Affinity Capture-MS Homo sapiens
115 DDX39B 7919
Affinity Capture-MS Homo sapiens
Co-purification Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
116 CEBPA  
Protein-peptide Homo sapiens
117 RAD21 5885
Affinity Capture-MS Homo sapiens
118 SRPK1 6732
Affinity Capture-MS Homo sapiens
119 RPA3 6119
Proximity Label-MS Homo sapiens
120 SNRPB2 6629
Affinity Capture-MS Homo sapiens
121 BCLAF1 9774
Affinity Capture-MS Homo sapiens
122 ARRB1 408
Affinity Capture-MS Homo sapiens
123 ATG16L1 55054
Affinity Capture-MS Homo sapiens
124 SFPQ 6421
Affinity Capture-MS Homo sapiens
125 RPL32 6161
Affinity Capture-MS Homo sapiens
126 OLA1 29789
Affinity Capture-MS Homo sapiens
127 RBM39 9584
Affinity Capture-MS Homo sapiens
128 LSM8 51691
Affinity Capture-MS Homo sapiens
129 PRPF4B 8899
Affinity Capture-MS Homo sapiens
130 MRRF  
Proximity Label-MS Homo sapiens
131 FANCD2  
Affinity Capture-MS Homo sapiens
132 NAA16 79612
Co-fractionation Homo sapiens
133 TRIM31  
Affinity Capture-MS Homo sapiens
134 XPO1 7514
Affinity Capture-MS Homo sapiens
135 RC3H2  
Affinity Capture-MS Homo sapiens
136 ECT2 1894
Affinity Capture-MS Homo sapiens
137 SIRT7  
Affinity Capture-MS Homo sapiens
138 SNRPB 6628
Affinity Capture-MS Homo sapiens
139 SRSF1 6426
Affinity Capture-MS Homo sapiens
140 PRMT8  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
141 CD274 29126
Affinity Capture-MS Homo sapiens
142 DIRAS2 54769
Affinity Capture-MS Homo sapiens
143 CUL3 8452
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
144 ERCC4  
Co-fractionation Homo sapiens
145 XPNPEP3 63929
Affinity Capture-MS Homo sapiens
146 GLI1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
147 THOC5 8563
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
148 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
149 FUS 2521
Affinity Capture-MS Homo sapiens
150 BAP1 8314
Affinity Capture-MS Homo sapiens
151 MYC  
Affinity Capture-MS Homo sapiens
152 RBM33  
Affinity Capture-MS Homo sapiens
153 SUZ12  
Affinity Capture-MS Homo sapiens
154 FN1 2335
Affinity Capture-MS Homo sapiens
155 NXF1 10482
Reconstituted Complex Homo sapiens
156 SCYL2 55681
Affinity Capture-MS Homo sapiens
157 SF3A1 10291
Affinity Capture-MS Homo sapiens
158 EFTUD2 9343
Affinity Capture-MS Homo sapiens
159 C12orf65  
Proximity Label-MS Homo sapiens
160 CDK2 1017
Affinity Capture-MS Homo sapiens
161 CEP250 11190
Affinity Capture-MS Homo sapiens
162 ATP6V1E1 529
Co-fractionation Homo sapiens
163 SOAT1 6646
Affinity Capture-MS Homo sapiens
164 RBM42  
Affinity Capture-MS Homo sapiens
165 FBXO6 26270
Affinity Capture-MS Homo sapiens
166 PSPC1 55269
Affinity Capture-MS Homo sapiens
167 BAG1 573
Affinity Capture-MS Homo sapiens
168 NAP1L1 4673
Co-fractionation Homo sapiens
169 INO80B 83444
Affinity Capture-MS Homo sapiens
170 TSFM 10102
Proximity Label-MS Homo sapiens
171 RUNX2  
Reconstituted Complex Homo sapiens
172 TOP1 7150
Affinity Capture-MS Homo sapiens
173 SART3 9733
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
174 MATR3 9782
Affinity Capture-MS Homo sapiens
175 DDRGK1 65992
Affinity Capture-MS Homo sapiens
176 RNF2  
Affinity Capture-MS Homo sapiens
177 ILK 3611
Affinity Capture-MS Homo sapiens
178 NR5A1  
Affinity Capture-RNA Homo sapiens
179 AKT1 207
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
180 NANOG  
Affinity Capture-MS Homo sapiens
181 UHRF1 29128
Affinity Capture-RNA Homo sapiens
182 LMNA 4000
Proximity Label-MS Homo sapiens
183 ZC3H11A  
Co-fractionation Homo sapiens
184 PXK 54899
Affinity Capture-MS Homo sapiens
185 RPS16 6217
Affinity Capture-MS Homo sapiens
186 H2AFX 3014
Affinity Capture-MS Homo sapiens
187 PAIP2B  
Affinity Capture-MS Homo sapiens
188 MARK3 4140
Affinity Capture-MS Homo sapiens
189 YBX1 4904
Co-fractionation Homo sapiens
190 GRK5 2869
Affinity Capture-MS Homo sapiens
191 ARRB2 409
Affinity Capture-MS Homo sapiens
192 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
193 LEF1  
Reconstituted Complex Homo sapiens
194 RC3H1 149041
Affinity Capture-MS Homo sapiens
195 AUH 549
Proximity Label-MS Homo sapiens
196 BKRF1  
Affinity Capture-MS
197 HDGF 3068
Affinity Capture-MS Homo sapiens
198 WDR77 79084
Affinity Capture-MS Homo sapiens
199 MCAT 27349
Affinity Capture-MS Homo sapiens
200 TP53 7157
Affinity Capture-MS Homo sapiens
201 UBA5 79876
Co-fractionation Homo sapiens
202 FOLR1 2348
Affinity Capture-MS Homo sapiens
203 IREB2 3658
Affinity Capture-MS Homo sapiens
204 THOC3  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
205 DDX3X 1654
Affinity Capture-MS Homo sapiens
206 SF3B4 10262
Co-fractionation Homo sapiens
207 TRIP13 9319
Co-fractionation Homo sapiens
208 USP36  
Affinity Capture-MS Homo sapiens
209 SAP18 10284
Co-fractionation Homo sapiens
210 PDHA1 5160
Affinity Capture-MS Homo sapiens
211 HNRNPM 4670
Co-fractionation Homo sapiens
212 RNH1 6050
Affinity Capture-MS Homo sapiens
213 SMAD4  
Affinity Capture-RNA Homo sapiens
214 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
215 INSIG2  
Affinity Capture-MS Homo sapiens
216 RBM15 64783
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
217 WDR35 57539
Co-fractionation Homo sapiens
218 EIF4A3 9775
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
219 GNL1 2794
Co-fractionation Homo sapiens
220 CDK1 983
Affinity Capture-MS Homo sapiens
221 PGAM2 5224
Cross-Linking-MS (XL-MS) Homo sapiens
222 ESR1  
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
223 PDZD8 118987
Affinity Capture-MS Homo sapiens
224 UFL1 23376
Affinity Capture-MS Homo sapiens
225 DDX39A 10212
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
226 COQ2  
Affinity Capture-MS Homo sapiens
227 IGF2BP3 10643
Affinity Capture-MS Homo sapiens
228 NCL 4691
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
229 ALYREF 10189
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
230 FGFR1OP2  
Affinity Capture-MS Homo sapiens
231 NEDD1 121441
Affinity Capture-MS Homo sapiens
232 CYLD  
Affinity Capture-MS Homo sapiens
233 UPF1 5976
Affinity Capture-MS Homo sapiens
234 MGME1  
Affinity Capture-MS Homo sapiens
235 IL7R  
Protein-RNA Homo sapiens
236 PRDX1 5052
Cross-Linking-MS (XL-MS) Homo sapiens
237 GRSF1 2926
Proximity Label-MS Homo sapiens
238 C1QBP 708
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
239 LSM6 11157
Affinity Capture-MS Homo sapiens
240 PRPF4 9128
Affinity Capture-MS Homo sapiens
241 CUL7 9820
Affinity Capture-MS Homo sapiens
242 KRAS 3845
Negative Genetic Homo sapiens
243 HNRNPU 3192
Affinity Capture-MS Homo sapiens
244 ZC3H13 23091
Affinity Capture-MS Homo sapiens
245 CLTCL1 8218
Affinity Capture-MS Homo sapiens
246 RBM34  
Co-fractionation Homo sapiens
247 SSRP1 6749
Affinity Capture-MS Homo sapiens
248 Kif1c  
Affinity Capture-MS Mus musculus
249 SRSF7 6432
Affinity Capture-MS Homo sapiens
250 PRMT1 3276
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
251 CPSF6 11052
Affinity Capture-MS Homo sapiens
252 EP300 2033
Affinity Capture-MS Homo sapiens
253 CASC3  
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here