Gene description for Rrp1b
Gene name ribosomal RNA processing 1 homolog B (S. cerevisiae)
Gene symbol Rrp1b
Other names/aliases 2600005C20Rik
D030064A17
Kiaa0179
mKIAA0179
Species Mus musculus
 Database cross references - Rrp1b
ExoCarta ExoCarta_72462
Vesiclepedia VP_72462
Entrez Gene 72462
UniProt Q91YK2  
 Rrp1b identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Rrp1b
Molecular Function
    transcription coactivator activity GO:0003713 ISO
    transcription coactivator activity GO:0003713 ISS
    protein binding GO:0005515 IPI
Biological Process
    rRNA processing GO:0006364 IEA
    mRNA processing GO:0006397 IEA
    apoptotic process GO:0006915 IEA
    RNA splicing GO:0008380 IEA
    negative regulation of GTPase activity GO:0034260 IMP
    positive regulation of apoptotic process GO:0043065 ISO
    positive regulation of apoptotic process GO:0043065 ISS
    regulation of RNA splicing GO:0043484 IMP
    positive regulation by host of viral transcription GO:0043923 IEA
    positive regulation by host of viral transcription GO:0043923 ISO
    positive regulation of transcription by RNA polymerase II GO:0045944 ISO
    positive regulation of transcription by RNA polymerase II GO:0045944 ISS
    cellular response to virus GO:0098586 IEA
    cellular response to virus GO:0098586 ISO
Subcellular Localization
    euchromatin GO:0000791 IDA
    heterochromatin GO:0000792 IDA
    granular component GO:0001652 ISO
    granular component GO:0001652 ISS
    nucleus GO:0005634 IBA
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 IEA
    nucleoplasm GO:0005654 ISO
    chromosome GO:0005694 ISO
    nucleolus GO:0005730 ISO
    nucleolus GO:0005730 ISS
    preribosome, small subunit precursor GO:0030688 IEA
 Experiment description of studies that identified Rrp1b in exosomes
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Rrp1b
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 RSL1D1 26156
Affinity Capture-MS Homo sapiens
2 CDCA8 55143
Affinity Capture-MS Homo sapiens
3 RALGAPA1 253959
Affinity Capture-MS Homo sapiens
4 PARP1 142
Affinity Capture-MS Homo sapiens
5 PRPF4B 8899
Affinity Capture-MS Homo sapiens
6 ILF3 3609
Affinity Capture-MS Homo sapiens
7 LRRC59 55379
Affinity Capture-MS Homo sapiens
8 ERH 2079
Affinity Capture-MS Homo sapiens
9 Twist1  
Proximity Label-MS Mus musculus
10 PPP1CA 5499
Affinity Capture-MS Homo sapiens
11 IGKC 3514
Affinity Capture-MS Homo sapiens
12 Cebpa  
Affinity Capture-MS Mus musculus
13 DDX21 9188
Affinity Capture-MS Homo sapiens
14 TAB1 10454
Affinity Capture-MS Homo sapiens
15 RPL4 6124
Affinity Capture-MS Homo sapiens
16 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
17 ITGAD  
Affinity Capture-MS Homo sapiens
18 HNRNPUL1 11100
Affinity Capture-MS Homo sapiens
19 MKI67  
Affinity Capture-MS Homo sapiens
20 RCN1 5954
Affinity Capture-MS Homo sapiens
21 STAU1 6780
Affinity Capture-MS Homo sapiens
22 SRSF6 6431
Affinity Capture-MS Homo sapiens
23 LRRC3DN  
Affinity Capture-MS Homo sapiens
24 RPL5 6125
Affinity Capture-MS Homo sapiens
25 RPL10A 4736
Affinity Capture-MS Homo sapiens
26 C1QBP 708
Affinity Capture-MS Homo sapiens
27 TRIM28 10155
Affinity Capture-MS Homo sapiens
28 NCL 4691
Affinity Capture-MS Homo sapiens
29 ALYREF 10189
Affinity Capture-MS Homo sapiens
30 DDX47 51202
Affinity Capture-MS Homo sapiens
31 NEDD1 121441
Affinity Capture-MS Homo sapiens
32 YBX3 8531
Affinity Capture-MS Homo sapiens
33 DNAJC9 23234
Affinity Capture-MS Homo sapiens
34 H1FX 8971
Affinity Capture-MS Homo sapiens
35 CUBN 8029
Affinity Capture-MS Homo sapiens
36 LYAR 55646
Affinity Capture-MS Homo sapiens
37 LUC7L2 51631
Affinity Capture-MS Homo sapiens
38 SRSF1 6426
Affinity Capture-MS Homo sapiens
39 NPM1 4869
Affinity Capture-MS Homo sapiens
40 IGKV2-40  
Affinity Capture-MS Homo sapiens
41 Eed  
Affinity Capture-MS Mus musculus
42 RPLP0 6175
Affinity Capture-MS Homo sapiens
43 RRP1B 23076
Affinity Capture-MS Homo sapiens
44 SRP14 6727
Affinity Capture-MS Homo sapiens
45 PRKAR1A 5573
Affinity Capture-MS Homo sapiens
46 LUC7L3 51747
Affinity Capture-MS Homo sapiens
47 YY2  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which Rrp1b is involved
No pathways found





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