Gene description for TRIM28
Gene name	tripartite motif containing 28
Gene symbol	TRIM28
Other names/aliases	KAP1 PPP1R157 RNF96 TF1B TIF1B
Species	Homo sapiens
Database cross references - TRIM28
ExoCarta	ExoCarta_10155
Entrez Gene	10155
HGNC	16384
MIM	601742
UniProt	Q13263
TRIM28 identified in exosomes derived from the following tissue/cell type
Neuroblastoma cells	25944692
Ovarian cancer cells	23333927
Ovarian cancer cells	23333927
Thymus	23844026

Gene ontology annotations for TRIM28

Molecular Function     DNA binding GO:0003677 IDA     transcription corepressor activity GO:0003714 IDA     Krueppel-associated box domain binding GO:0035851 IDA     zinc ion binding GO:0008270 IDA     ubiquitin-protein transferase activity GO:0004842 IDA     chromo shadow domain binding GO:0070087 IPI     ligase activity GO:0016874 IEA     transcription coactivator activity GO:0003713 IEA     ubiquitin protein ligase binding GO:0031625 IDA     protein kinase activity GO:0004672 IEA     sequence-specific DNA binding transcription factor activity GO:0003700 ISS     poly(A) RNA binding GO:0044822 IDA     sequence-specific DNA binding GO:0043565 ISS     protein binding GO:0005515 IPI Biological Process     negative regulation of viral release from host cell GO:1902187 IDA     embryonic placenta morphogenesis GO:0060669 IEA     protein ubiquitination GO:0016567 IDA     negative regulation of transcription, DNA-templated GO:0045892 IDA     transcription initiation from RNA polymerase II promoter GO:0006367 TAS     negative regulation of DNA demethylation GO:1901536 IEA     DNA repair GO:0006281 IDA     positive regulation of transcription, DNA-templated GO:0045893 ISS     embryo implantation GO:0007566 IEA     regulation of genetic imprinting GO:2000653 IEA     epithelial to mesenchymal transition GO:0001837 ISS     protein oligomerization GO:0051259 IDA     innate immune response GO:0045087 IDA     DNA methylation involved in embryo development GO:0043045 IEA     protein autophosphorylation GO:0046777 IEA     gene expression GO:0010467 TAS     protein sumoylation GO:0016925 IEA     positive regulation of transcription factor import into nucleus GO:0042993 IDA     negative regulation of transcription from RNA polymerase II promoter GO:0000122 IEA     positive regulation of DNA repair GO:0045739 IDA     convergent extension involved in axis elongation GO:0060028 IEA Subcellular Localization     nucleus GO:0005634 ISS     nuclear euchromatin GO:0005719 IEA     nuclear heterochromatin GO:0005720 IEA     nucleoplasm GO:0005654 TAS     RNA polymerase II transcription factor complex GO:0090575 ISS