Gene description for DDX21
Gene name DEAD (Asp-Glu-Ala-Asp) box helicase 21
Gene symbol DDX21
Other names/aliases GUA
GURDB
RH-II/GU
RH-II/GuA
Species Homo sapiens
 Database cross references - DDX21
ExoCarta ExoCarta_9188
Vesiclepedia VP_9188
Entrez Gene 9188
HGNC 2744
MIM 606357
UniProt Q9NR30  
 DDX21 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 34887515    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 36706192    
Embryonic kidney cells 36706192    
Endothelial cells 26027894    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Plasma 19028452    
Pluripotent stem cells 34108659    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
T lymphocytes 34108659    
Thymus 23844026    
 Gene ontology annotations for DDX21
Molecular Function
    DNA clamp loader activity GO:0003689 IEA
    RNA binding GO:0003723 HDA
    RNA helicase activity GO:0003724 IBA
    RNA helicase activity GO:0003724 IDA
    RNA helicase activity GO:0003724 IMP
    double-stranded RNA binding GO:0003725 IEA
    mRNA binding GO:0003729 IBA
    protein binding GO:0005515 IPI
    ATP binding GO:0005524 IEA
    ATP hydrolysis activity GO:0016887 IEA
    rRNA binding GO:0019843 IDA
    snoRNA binding GO:0030515 IDA
    miRNA binding GO:0035198 IDA
    identical protein binding GO:0042802 IEA
    cohesin loader activity GO:0061775 IEA
    7SK snRNA binding GO:0097322 IDA
    chromatin extrusion motor activity GO:0140584 IEA
    ATP-dependent H3-H4 histone complex chaperone activity GO:0140665 IEA
    ATP-dependent H2AZ histone chaperone activity GO:0140849 IEA
    RNA polymerase inhibitor activity GO:0140870 TAS
Biological Process
    osteoblast differentiation GO:0001649 HDA
    positive regulation of myeloid dendritic cell cytokine production GO:0002735 IEA
    chromatin remodeling GO:0006338 NAS
    rRNA processing GO:0006364 IEA
    transcription by RNA polymerase II GO:0006366 IMP
    negative regulation of transcription by RNA polymerase I GO:0016479 TAS
    positive regulation of canonical NF-kappaB signal transduction GO:0043123 ISS
    response to exogenous dsRNA GO:0043330 IEA
    innate immune response GO:0045087 IEA
    positive regulation of transcription by RNA polymerase I GO:0045943 NAS
    positive regulation of transcription by RNA polymerase II GO:0045944 NAS
    positive regulation of transcription by RNA polymerase III GO:0045945 IDA
    defense response to virus GO:0051607 IEA
    R-loop processing GO:0062176 IDA
    chromatin looping GO:0140588 IEA
Subcellular Localization
    nucleoplasm GO:0005654 IDA
    nucleoplasm GO:0005654 TAS
    chromosome GO:0005694 IDA
    nucleolus GO:0005730 IBA
    nucleolus GO:0005730 IDA
    nucleolus GO:0005730 NAS
    mitochondrion GO:0005739 IEA
    cytosol GO:0005829 ISS
    membrane GO:0016020 HDA
    B-WICH complex GO:0110016 IDA
 Experiment description of studies that identified DDX21 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
10
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
11
Experiment ID 1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
12
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
13
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
14
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
15
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
16
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
17
Experiment ID 1275
MISEV standards
Biophysical techniques
✔
CD9|TSG101|FLOT1|FLOT2|RAB35|RAB5A|GAPDH|TFRC|CD63|Alix
Enriched markers
✔
PCNA|CANX|GAPDH|HSP90AA1|HSP90B1
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
18
Experiment ID 1280
MISEV standards
Biophysical techniques
✔
TSG101|CD9|FLOT1|FLOT2|RAB35|RAB5A|GAPDH|TFRC|CD63|Alix
Enriched markers
✔
PCNA|CANX|GAPDH|HSP90AA1|HSP90B1
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T - Fraction 5
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density 1.151 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
19
Experiment ID 226
MISEV standards
✔
EM
Biophysical techniques
✔
GAPDH|CD9|FLOT1
Enriched markers
✔
LMNA|H2AFX|ATP5A1|TOMM20
Negative markers
✘ Particle analysis
Identified molecule mRNA
Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
PubMed ID 26027894    
Organism Homo sapiens
Experiment description "Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting"
Authors "Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar"
Journal name Journal of Extracellular Vesicles
Publication year 2015
Sample Endothelial cells
Sample name HMEC-1
Isolation/purification methods Differential ultracentrifugation
Sucrose density gradient
Flotation density 1.10 g/mL
Molecules identified in the study miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA
Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting
20
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
21
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
22
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
23
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
24
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
25
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
26
Experiment ID 254
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name MNT-1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
27
Experiment ID 255
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name G1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
28
Experiment ID 256
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 501mel
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
29
Experiment ID 257
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name Daju
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
30
Experiment ID 258
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name SKMEL28
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
31
Experiment ID 259
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name A375M
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
32
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
33
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
34
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
35
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
36
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
37
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
38
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
39
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
40
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
41
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
42
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
43
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
44
Experiment ID 44
MISEV standards
✔
IEM
Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19028452    
Organism Homo sapiens
Experiment description Proteomic profiling of human plasma exosomes identifies PPARgamma as an exosome-associated protein.
Authors "Looze C, Yui D, Leung L, Ingham M, Kaler M, Yao X, Wu WW, Shen RF, Daniels MP, Levine SJ"
Journal name BBRC
Publication year 2009
Sample Plasma
Sample name Plasma
Isolation/purification methods Filtration
Size exclusion
Sucrose density gradient
Flotation density 1.15-1.16 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy
45
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
46
Experiment ID 834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
47
Experiment ID 835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
48
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
49
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for DDX21
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 EIF3A 8661
Affinity Capture-MS Homo sapiens
2 RPSAP58 388524
Affinity Capture-MS Homo sapiens
3 HDAC4  
Affinity Capture-MS Homo sapiens
4 TRMT1L 81627
Affinity Capture-MS Homo sapiens
5 ZNF771  
Affinity Capture-MS Homo sapiens
6 RPS28 6234
Affinity Capture-MS Homo sapiens
7 MACROD1 28992
Affinity Capture-MS Homo sapiens
8 KPNA1 3836
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
9 PRPF8 10594
Affinity Capture-MS Homo sapiens
10 SRPK2 6733
Affinity Capture-Western Homo sapiens
FRET Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 RTCA 8634
Affinity Capture-MS Homo sapiens
12 DDX17 10521
Affinity Capture-MS Homo sapiens
13 ACTC1 70
Affinity Capture-MS Homo sapiens
14 NMNAT1  
Affinity Capture-MS Homo sapiens
15 KIF20A 10112
Affinity Capture-MS Homo sapiens
16 SNRNP40 9410
Affinity Capture-MS Homo sapiens
17 CSNK2A1 1457
Biochemical Activity Homo sapiens
18 PNMAL1  
Affinity Capture-MS Homo sapiens
19 PRPF40A 55660
Affinity Capture-MS Homo sapiens
20 SOX2  
Affinity Capture-MS Homo sapiens
21 AKAP8L  
Affinity Capture-MS Homo sapiens
22 PTPRB 5787
Affinity Capture-MS Homo sapiens
23 DDX23 9416
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
24 GPATCH4 54865
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
25 IGF2BP3 10643
Affinity Capture-MS Homo sapiens
26 SNRNP70 6625
Affinity Capture-MS Homo sapiens
27 RBM28 55131
Affinity Capture-MS Homo sapiens
28 CDK9 1025
Affinity Capture-MS Homo sapiens
29 KIF23 9493
Affinity Capture-MS Homo sapiens
30 SF3B1 23451
Co-fractionation Homo sapiens
31 NUP153 9972
Affinity Capture-MS Homo sapiens
32 RAB21 23011
Affinity Capture-MS Homo sapiens
33 RPS9 6203
Affinity Capture-MS Homo sapiens
34 RPF2 84154
Affinity Capture-MS Homo sapiens
35 CENPQ  
Affinity Capture-MS Homo sapiens
36 Nhp2l1 20826
Affinity Capture-MS Mus musculus
37 MECP2 4204
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
38 ARIH2 10425
Affinity Capture-MS Homo sapiens
39 RPS11 6205
Co-fractionation Homo sapiens
40 RPL19 6143
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
41 KIF14 9928
Affinity Capture-MS Homo sapiens
42 RBMX 27316
Affinity Capture-MS Homo sapiens
43 HEXIM1 10614
Affinity Capture-MS Homo sapiens
44 CHMP4C 92421
Affinity Capture-MS Homo sapiens
45 LIN28B  
Affinity Capture-MS Homo sapiens
46 MEPCE 56257
Affinity Capture-MS Homo sapiens
47 SRSF3 6428
Affinity Capture-MS Homo sapiens
48 YBX2 51087
Affinity Capture-MS Homo sapiens
49 MAPRE1 22919
Affinity Capture-MS Homo sapiens
50 CLTCL1 8218
Affinity Capture-MS Homo sapiens
51 PURG  
Affinity Capture-MS Homo sapiens
52 HIST1H3E 8353
Affinity Capture-MS Homo sapiens
53 HIST1H2AM 8336
Affinity Capture-MS Homo sapiens
54 RPL18A 6142
Affinity Capture-MS Homo sapiens
55 PABPC1 26986
Affinity Capture-MS Homo sapiens
56 Srp72  
Affinity Capture-MS Mus musculus
57 YAP1 10413
Affinity Capture-MS Homo sapiens
58 PDS5A 23244
Co-fractionation Homo sapiens
59 Ddx21 56200
Affinity Capture-MS Mus musculus
60 FGF8  
Affinity Capture-MS Homo sapiens
61 SYNCRIP 10492
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
62 CBX6  
Affinity Capture-MS Homo sapiens
63 HIST1H1C 3006
Affinity Capture-MS Homo sapiens
64 ZFP91 80829
Affinity Capture-MS Homo sapiens
65 HECTD1 25831
Affinity Capture-MS Homo sapiens
66 RRP1B 23076
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
67 SRPK3  
Affinity Capture-MS Homo sapiens
68 SON 6651
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
69 DDX39B 7919
Affinity Capture-MS Homo sapiens
70 PPIH 10465
Affinity Capture-MS Homo sapiens
71 GTPBP4 23560
Affinity Capture-MS Homo sapiens
72 CCNT1  
Affinity Capture-MS Homo sapiens
73 SLC25A5 292
Cross-Linking-MS (XL-MS) Homo sapiens
74 CD3EAP  
Proximity Label-MS Homo sapiens
75 CNBP 7555
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
76 ANLN 54443
Affinity Capture-MS Homo sapiens
77 RBM39 9584
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
78 NFAT5  
Affinity Capture-MS Homo sapiens
79 NOC3L 64318
Affinity Capture-MS Homo sapiens
80 LMNB1 4001
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
81 SIRT7  
Affinity Capture-MS Homo sapiens
82 SRSF4 6429
Affinity Capture-MS Homo sapiens
83 NPM3 10360
Affinity Capture-MS Homo sapiens
84 CUL3 8452
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
85 SHQ1  
Affinity Capture-MS Homo sapiens
86 EBNA1BP2 10969
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
87 POLR2D  
Affinity Capture-MS Homo sapiens
88 RPL7L1 285855
Affinity Capture-MS Homo sapiens
89 ZC3H11A  
Affinity Capture-MS Homo sapiens
90 SLTM 79811
Affinity Capture-MS Homo sapiens
91 NIP7 51388
Affinity Capture-MS Homo sapiens
92 FN1 2335
Affinity Capture-MS Homo sapiens
93 YTHDC1  
Affinity Capture-MS Homo sapiens
94 ZNF512  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
95 HIST1H1B 3009
Affinity Capture-MS Homo sapiens
96 HNRNPR 10236
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
97 RPA3 6119
Proximity Label-MS Homo sapiens
98 DLST 1743
Affinity Capture-MS Homo sapiens
99 DDX54 79039
Affinity Capture-MS Homo sapiens
100 ILK 3611
Affinity Capture-MS Homo sapiens
101 Rpl35 66489
Affinity Capture-MS Mus musculus
102 ZFP62  
Affinity Capture-MS Homo sapiens
103 SUPT16H 11198
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
104 RPS16 6217
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
105 U2SURP 23350
Affinity Capture-MS Homo sapiens
106 YBX1 4904
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
107 GRK5 2869
Affinity Capture-MS Homo sapiens
108 RPS27A 6233
Affinity Capture-MS Homo sapiens
109 C8orf33 65265
Affinity Capture-MS Homo sapiens
110 RPLP0 6175
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
111 CHTOP  
Affinity Capture-MS Homo sapiens
112 RRS1 23212
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
113 WWOX 51741
Affinity Capture-MS Homo sapiens
114 ZEB1  
Affinity Capture-MS Homo sapiens
115 SRSF9 8683
Affinity Capture-MS Homo sapiens
116 CWF19L2  
Affinity Capture-MS Homo sapiens
117 TRA2B 6434
Affinity Capture-MS Homo sapiens
118 RPS15A 6210
Affinity Capture-MS Homo sapiens
119 SUGP2  
Affinity Capture-MS Homo sapiens
120 KRR1 11103
Affinity Capture-MS Homo sapiens
121 LARP7 51574
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
122 NEIL1  
Affinity Capture-MS Homo sapiens
123 IK 3550
Co-fractionation Homo sapiens
124 RPS24 6229
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
125 NCL 4691
Affinity Capture-MS Homo sapiens
126 ALYREF 10189
Affinity Capture-MS Homo sapiens
127 HNRNPL 3191
Affinity Capture-MS Homo sapiens
128 RPL23AP32 56969
Affinity Capture-MS Homo sapiens
129 PRPF4 9128
Affinity Capture-MS Homo sapiens
130 CUL7 9820
Affinity Capture-MS Homo sapiens
131 CRNKL1 51340
Affinity Capture-MS Homo sapiens
132 MTCL1 23255
Affinity Capture-MS Homo sapiens
133 PURA 5813
Affinity Capture-MS Homo sapiens
134 NVL  
Affinity Capture-MS Homo sapiens
135 IMP4  
Affinity Capture-MS Homo sapiens
136 LUZP4  
Affinity Capture-MS Homo sapiens
137 H1FNT  
Affinity Capture-MS Homo sapiens
138 NCBP1 4686
Affinity Capture-MS Homo sapiens
139 KPNA3 3839
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
140 KIAA0020 9933
Affinity Capture-MS Homo sapiens
141 GTPBP10  
Affinity Capture-MS Homo sapiens
142 THRAP3 9967
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
143 APC  
Affinity Capture-MS Homo sapiens
144 USP39 10713
Affinity Capture-MS Homo sapiens
145 NOP56 10528
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
146 HNRNPD 3184
Affinity Capture-MS Homo sapiens
147 RPL14 9045
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
148 URB2  
Affinity Capture-MS Homo sapiens
149 TARDBP 23435
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
150 RSBN1  
Affinity Capture-MS Homo sapiens
151 RBM34  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
152 SNRPF 6636
Affinity Capture-MS Homo sapiens
153 SFPQ 6421
Co-fractionation Homo sapiens
154 RPS18 6222
Affinity Capture-MS Homo sapiens
155 SURF2  
Affinity Capture-MS Homo sapiens
156 RNPS1 10921
Co-fractionation Homo sapiens
157 DDX24 57062
Affinity Capture-MS Homo sapiens
158 H1FX 8971
Affinity Capture-MS Homo sapiens
159 RRP12 23223
Affinity Capture-MS Homo sapiens
160 PRC1 9055
Affinity Capture-MS Homo sapiens
161 MAGOHB 55110
Affinity Capture-MS Homo sapiens
162 NPM1 4869
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
163 SRRM2 23524
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
164 KHDRBS1 10657
Affinity Capture-MS Homo sapiens
165 OBSL1 23363
Affinity Capture-MS Homo sapiens
166 RSRC1  
Affinity Capture-MS Homo sapiens
167 VCAM1 7412
Affinity Capture-MS Homo sapiens
168 E4F1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
169 RBM42  
Affinity Capture-MS Homo sapiens
170 OASL 8638
Affinity Capture-MS Homo sapiens
171 RRP7A 27341
Co-fractionation Homo sapiens
172 ZCRB1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
173 LSM2 57819
Affinity Capture-MS Homo sapiens
174 PHF10  
Affinity Capture-MS Homo sapiens
175 HNRNPA0 10949
Affinity Capture-MS Homo sapiens
176 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
177 USP10 9100
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
178 RPL4 6124
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
179 WHSC1 7468
Affinity Capture-MS Homo sapiens
180 DRG1 4733
Affinity Capture-MS Homo sapiens
181 MSX2  
Affinity Capture-MS Homo sapiens
182 TRA2A 29896
Affinity Capture-MS Homo sapiens
183 PNN 5411
Affinity Capture-MS Homo sapiens
184 ACIN1 22985
Affinity Capture-MS Homo sapiens
185 SNRNP200 23020
Affinity Capture-MS Homo sapiens
186 VRK1 7443
Affinity Capture-MS Homo sapiens
187 NFIA 4774
Co-fractionation Homo sapiens
188 NELFE 7936
Affinity Capture-MS Homo sapiens
189 NKRF 55922
Affinity Capture-MS Homo sapiens
190 REXO4  
Affinity Capture-MS Homo sapiens
191 RBMX2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
192 LYAR 55646
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
193 CTR9 9646
Affinity Capture-MS Homo sapiens
194 APTX  
Affinity Capture-MS Homo sapiens
195 DDX27 55661
Affinity Capture-MS Homo sapiens
196 PRPF3  
Affinity Capture-MS Homo sapiens
197 RSL1D1 26156
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
198 ZCCHC8 55596
Affinity Capture-MS Homo sapiens
199 FGFBP1 9982
Affinity Capture-MS Homo sapiens
200 CENPN  
Affinity Capture-MS Homo sapiens
201 PPAN-P2RY11  
Affinity Capture-MS Homo sapiens
202 RPL32 6161
Affinity Capture-MS Homo sapiens
203 RPS2 6187
Affinity Capture-MS Homo sapiens
204 POP1 10940
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
205 RC3H2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
206 IKZF3  
Affinity Capture-MS Homo sapiens
207 POLR2E 5434
Affinity Capture-MS Homo sapiens
208 YLPM1 56252
Affinity Capture-MS Homo sapiens
209 SRSF5 6430
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
210 IKZF1  
Affinity Capture-MS Homo sapiens
211 MYO1C 4641
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
212 EFTUD2 9343
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
213 CDK2 1017
Affinity Capture-MS Homo sapiens
214 CEP250 11190
Affinity Capture-MS Homo sapiens
215 MYC  
Affinity Capture-MS Homo sapiens
216 BAG1 573
Affinity Capture-MS Homo sapiens
217 CEBPZ  
Affinity Capture-MS Homo sapiens
218 ZCCHC6 79670
Affinity Capture-MS Homo sapiens
219 SART3 9733
Affinity Capture-MS Homo sapiens
220 RPL23A 6147
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
221 DDRGK1 65992
Affinity Capture-MS Homo sapiens
222 ARGLU1  
Affinity Capture-MS Homo sapiens
223 H2AFB2  
Affinity Capture-MS Homo sapiens
224 CCDC140  
Affinity Capture-MS Homo sapiens
225 HIST1H1T 3010
Affinity Capture-MS Homo sapiens
226 RPL26 6154
Affinity Capture-MS Homo sapiens
227 FTSJ3 117246
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
228 HUWE1 10075
Affinity Capture-MS Homo sapiens
229 EIF3H 8667
Affinity Capture-MS Homo sapiens
230 FAM120A 23196
Affinity Capture-MS Homo sapiens
231 PA2G4 5036
Affinity Capture-MS Homo sapiens
232 RPL13 6137
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
233 SURF6  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
234 PRKCSH 5589
Cross-Linking-MS (XL-MS) Homo sapiens
235 TERF2  
Two-hybrid Homo sapiens
236 PARP1 142
Co-fractionation Homo sapiens
237 TAF1A  
Affinity Capture-MS Homo sapiens
238 TP53 7157
Affinity Capture-MS Homo sapiens
239 AKAP8  
Affinity Capture-MS Homo sapiens
240 KIAA2012  
Cross-Linking-MS (XL-MS) Homo sapiens
241 RPS5 6193
Affinity Capture-MS Homo sapiens
242 CHD2 1106
Cross-Linking-MS (XL-MS) Homo sapiens
243 HNRNPK 3190
Affinity Capture-MS Homo sapiens
244 ESR1  
Affinity Capture-MS Homo sapiens
245 RBM23  
Affinity Capture-MS Homo sapiens
246 NOC2L 26155
Affinity Capture-MS Homo sapiens
247 EEF1A1P5 158078
Cross-Linking-MS (XL-MS) Homo sapiens
248 YBX3 8531
Affinity Capture-MS Homo sapiens
249 RPL7A 6130
Affinity Capture-MS Homo sapiens
250 C1QBP 708
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
251 KRAS 3845
Negative Genetic Homo sapiens
252 MAST3  
Affinity Capture-MS Homo sapiens
253 PRMT1 3276
Affinity Capture-MS Homo sapiens
254 CUL4A 8451
Affinity Capture-MS Homo sapiens
255 RALY 22913
Affinity Capture-MS Homo sapiens
256 NOP14 8602
Cross-Linking-MS (XL-MS) Homo sapiens
257 HNRNPC 3183
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
258 RPL26L1 51121
Affinity Capture-MS Homo sapiens
259 DNAJC9 23234
Proximity Label-MS Homo sapiens
260 RPS26 6231
Affinity Capture-MS Homo sapiens
261 YWHAE 7531
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
262 SDAD1  
Affinity Capture-MS Homo sapiens
263 ZNF326 284695
Affinity Capture-MS Homo sapiens
264 RPS19 6223
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
265 SSB 6741
Affinity Capture-MS Homo sapiens
266 FGF3  
Affinity Capture-MS Homo sapiens
267 FAU 2197
Affinity Capture-MS Homo sapiens
268 HNRNPUL2 221092
Affinity Capture-MS Homo sapiens
269 Rrp1b 72462
Affinity Capture-MS Mus musculus
270 RPL10A 4736
Affinity Capture-MS Homo sapiens
271 HNRNPAB 3182
Affinity Capture-MS Homo sapiens
272 LLPH  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
273 MCM2 4171
Affinity Capture-MS Homo sapiens
274 RANBP10 57610
Affinity Capture-MS Homo sapiens
275 SMARCA1 6594
Co-fractionation Homo sapiens
276 CCDC137  
Affinity Capture-MS Homo sapiens
277 MPHOSPH10 10199
Cross-Linking-MS (XL-MS) Homo sapiens
278 ANOS1 3730
Affinity Capture-MS Homo sapiens
279 LINC00240  
Protein-RNA Homo sapiens
Affinity Capture-MS Homo sapiens
280 SRP14 6727
Affinity Capture-MS Homo sapiens
281 HIST2H2AC 8338
Affinity Capture-MS Homo sapiens
282 ITGA4 3676
Affinity Capture-MS Homo sapiens
283 DDX18 8886
Affinity Capture-MS Homo sapiens
284 NHP2 55651
Affinity Capture-MS Homo sapiens
285 TFCP2 7024
Affinity Capture-MS Homo sapiens
286 SERBP1 26135
Affinity Capture-MS Homo sapiens
287 THOC1 9984
Affinity Capture-MS Homo sapiens
288 RBM8A 9939
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
289 RBM19 9904
Affinity Capture-MS Homo sapiens
290 BRIX1 55299
Affinity Capture-MS Homo sapiens
291 RPL27 6155
Affinity Capture-MS Homo sapiens
292 DDX31  
Affinity Capture-MS Homo sapiens
293 CDKN2AIP  
Affinity Capture-MS Homo sapiens
294 VEZF1  
Cross-Linking-MS (XL-MS) Homo sapiens
295 SRRT 51593
Affinity Capture-MS Homo sapiens
296 Ctcf 13018
Affinity Capture-MS Mus musculus
297 RPL9 6133
Affinity Capture-MS Homo sapiens
298 ADAR 103
Affinity Capture-MS Homo sapiens
299 PARK2  
Affinity Capture-MS Homo sapiens
300 CENPV 201161
Affinity Capture-MS Homo sapiens
301 RPS10 6204
Affinity Capture-MS Homo sapiens
302 PNO1 56902
Affinity Capture-MS Homo sapiens
303 DOT1L 84444
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
304 NOP2 4839
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
305 KPNA4 3840
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
306 RPL5 6125
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
307 ZCCHC17  
Affinity Capture-MS Homo sapiens
308 DEK 7913
Co-fractionation Homo sapiens
309 CHMP4B 128866
Affinity Capture-MS Homo sapiens
310 SAFB2 9667
Affinity Capture-MS Homo sapiens
311 NTRK1 4914
Affinity Capture-MS Homo sapiens
312 U2AF2 11338
Affinity Capture-MS Homo sapiens
313 RPL36 25873
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
314 RPA4  
Proximity Label-MS Homo sapiens
315 DHX9 1660
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
316 ZC3H14  
Affinity Capture-MS Homo sapiens
317 C1orf131  
Affinity Capture-MS Homo sapiens
318 HNRNPA3 220988
Affinity Capture-MS Homo sapiens
319 MYBBP1A 10514
Affinity Capture-MS Homo sapiens
320 DNM1L 10059
Affinity Capture-MS Homo sapiens
321 MRPL2 51069
Affinity Capture-MS Homo sapiens
322 RPL11 6135
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
323 LARP1 23367
Affinity Capture-MS Homo sapiens
324 WDR46  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
325 HNRNPDL 9987
Affinity Capture-MS Homo sapiens
326 RPL31 6160
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
327 THUMPD1 55623
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
328 METTL14  
Affinity Capture-MS Homo sapiens
329 CHERP 10523
Affinity Capture-MS Homo sapiens
330 SMARCA5 8467
Co-fractionation Homo sapiens
331 FAM60A  
Affinity Capture-MS Homo sapiens
332 ZFR 51663
Affinity Capture-MS Homo sapiens
333 HIST1H1E 3008
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
334 KPNB1 3837
Affinity Capture-MS Homo sapiens
335 DCAF13 25879
Affinity Capture-MS Homo sapiens
336 RPL21 6144
Affinity Capture-MS Homo sapiens
337 ZC3H8  
Affinity Capture-MS Homo sapiens
338 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
339 DHX30 22907
Affinity Capture-MS Homo sapiens
340 PDCD11 22984
Affinity Capture-MS Homo sapiens
341 NCBP2 22916
Affinity Capture-MS Homo sapiens
342 PRR3  
Affinity Capture-MS Homo sapiens
343 PSPC1 55269
Affinity Capture-MS Homo sapiens
344 ZC3H18  
Affinity Capture-MS Homo sapiens
345 TOP1 7150
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
346 RPL22 6146
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
347 HP1BP3 50809
Affinity Capture-MS Homo sapiens
348 SKIV2L2 23517
Affinity Capture-MS Homo sapiens
349 MATR3 9782
Affinity Capture-MS Homo sapiens
350 RPL18 6141
Affinity Capture-MS Homo sapiens
351 ZC3HAV1 56829
Affinity Capture-MS Homo sapiens
352 TSR1 55720
Affinity Capture-MS Homo sapiens
353 ILF3 3609
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
354 RBM17 84991
Affinity Capture-MS Homo sapiens
355 DDX50 79009
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
356 RPL37 6167
Affinity Capture-MS Homo sapiens
357 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
358 RPS3 6188
Affinity Capture-MS Homo sapiens
359 FBXL6  
Affinity Capture-MS Homo sapiens
360 RPL6 6128
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
361 MCM5 4174
Affinity Capture-MS Homo sapiens
362 PRRC2C 23215
Affinity Capture-MS Homo sapiens
363 MAGEB2 4113
Affinity Capture-MS Homo sapiens
364 SNRPA 6626
Affinity Capture-MS Homo sapiens
365 HNRNPM 4670
Affinity Capture-MS Homo sapiens
366 URB1 9875
Affinity Capture-MS Homo sapiens
367 S100A9 6280
Co-fractionation Homo sapiens
368 KPNA2 3838
Affinity Capture-MS Homo sapiens
369 RPL34 6164
Two-hybrid Homo sapiens
370 UFL1 23376
Affinity Capture-MS Homo sapiens
371 MED12  
Affinity Capture-MS Homo sapiens
372 RPS7 6201
Affinity Capture-MS Homo sapiens
373 RPL8 6132
Affinity Capture-MS Homo sapiens
374 RPL28 6158
Affinity Capture-MS Homo sapiens
375 ERG  
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
376 RPL36AL 6166
Affinity Capture-MS Homo sapiens
377 RC3H1 149041
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
378 SSRP1 6749
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
379 CDK11A 728642
Affinity Capture-MS Homo sapiens
380 IGF2BP2 10644
Affinity Capture-MS Homo sapiens
381 CASC3  
Affinity Capture-MS Homo sapiens
382 GNL2 29889
Affinity Capture-MS Homo sapiens
383 UBE2H 7328
Affinity Capture-MS Homo sapiens
384 RIT1 6016
Negative Genetic Homo sapiens
385 SLC4A7 9497
Cross-Linking-MS (XL-MS) Homo sapiens
386 IGF2BP1 10642
Affinity Capture-MS Homo sapiens
387 Sgol2  
Affinity Capture-MS Mus musculus
388 LGR4 55366
Affinity Capture-MS Homo sapiens
389 SCARNA22  
Affinity Capture-RNA Homo sapiens
390 RPS3A 6189
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
391 BCLAF1 9774
Affinity Capture-MS Homo sapiens
392 RPL30 6156
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
393 PPIE 10450
Affinity Capture-MS Homo sapiens
394 EIF3K 27335
Affinity Capture-MS Homo sapiens
395 RPL13A 23521
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
396 RPL37A 6168
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
397 Ybx1 22608
Affinity Capture-MS Mus musculus
398 CTNNBL1 56259
Affinity Capture-MS Homo sapiens
399 RPL10 6134
Affinity Capture-MS Homo sapiens
400 RPL15 6138
Affinity Capture-MS Homo sapiens
401 LAMP2 3920
Co-fractionation Homo sapiens
402 DNAJC25 548645
Affinity Capture-MS Homo sapiens
403 CALM1 801
Reconstituted Complex Homo sapiens
404 DHX57 90957
Affinity Capture-MS Homo sapiens
405 ILF2 3608
Affinity Capture-MS Homo sapiens
406 USP36  
Affinity Capture-MS Homo sapiens
407 SUB1 10923
Affinity Capture-MS Homo sapiens
408 TOP2A 7153
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
409 RPS20 6224
Affinity Capture-MS Homo sapiens
410 PCK1 5105
Affinity Capture-MS Homo sapiens
411 EIF4A3 9775
Affinity Capture-MS Homo sapiens
412 FBXW7  
Affinity Capture-MS Homo sapiens
413 SNRPC 6631
Affinity Capture-MS Homo sapiens
414 RPS8 6202
Affinity Capture-MS Homo sapiens
415 H2AFY2 55506
Affinity Capture-MS Homo sapiens
416 ADARB1 104
Affinity Capture-MS Homo sapiens
417 STAU2 27067
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
418 PRKRA 8575
Affinity Capture-MS Homo sapiens
419 DDX51  
Affinity Capture-MS Homo sapiens
420 NIFK 84365
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
421 EED  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
422 SRP68 6730
Affinity Capture-MS Homo sapiens
423 ABT1 29777
Affinity Capture-MS Homo sapiens
424 RRP8  
Affinity Capture-MS Homo sapiens
425 MYCN  
Affinity Capture-MS Homo sapiens
426 SSR3 6747
Co-fractionation Homo sapiens
427 MAK16  
Affinity Capture-MS Homo sapiens
428 KRI1  
Affinity Capture-MS Homo sapiens
429 CTCF  
Affinity Capture-MS Homo sapiens
430 CCDC86  
Affinity Capture-MS Homo sapiens
431 RPS23 6228
Co-fractionation Homo sapiens
432 GEMIN5 25929
Affinity Capture-MS Homo sapiens
433 ZKSCAN8  
Affinity Capture-MS Homo sapiens
434 COX15 1355
Affinity Capture-MS Homo sapiens
435 ECT2 1894
Affinity Capture-MS Homo sapiens
436 RB1CC1 9821
Affinity Capture-MS Homo sapiens
437 RPL39 6170
Affinity Capture-MS Homo sapiens
438 CCAR2 57805
Affinity Capture-MS Homo sapiens
439 ARMC8 25852
Affinity Capture-MS Homo sapiens
440 STAU1 6780
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
441 APOBEC3C 27350
Affinity Capture-MS Homo sapiens
442 SRSF6 6431
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
443 ZNF22  
Affinity Capture-MS Homo sapiens
444 UBE2I 7329
Biochemical Activity Homo sapiens
445 PCDHA2  
Co-fractionation Homo sapiens
446 DDX5 1655
Affinity Capture-MS Homo sapiens
447 IFI16 3428
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
448 SUMO2 6613
Reconstituted Complex Homo sapiens
449 RPL27A 6157
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
450 PABPN1 8106
Affinity Capture-MS Homo sapiens
451 UPF1 5976
Affinity Capture-MS Homo sapiens
452 SPTY2D1  
Affinity Capture-MS Homo sapiens
453 FGF13  
Affinity Capture-MS Homo sapiens
454 HIST1H2AB 8335
Affinity Capture-MS Homo sapiens
455 RBM5  
Cross-Linking-MS (XL-MS) Homo sapiens
456 DDX6 1656
Affinity Capture-MS Homo sapiens
457 BMS1  
Affinity Capture-MS Homo sapiens
458 TAF15 8148
Affinity Capture-MS Homo sapiens
459 PRPF4B 8899
Affinity Capture-MS Homo sapiens
460 RPLP2 6181
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
461 FANCD2  
Affinity Capture-MS Homo sapiens
462 TRIM31  
Affinity Capture-MS Homo sapiens
463 DNAJC2 27000
Affinity Capture-MS Homo sapiens
464 Dlg5  
Affinity Capture-MS Mus musculus
465 RPL35 11224
Affinity Capture-MS Homo sapiens
466 SAFB 6294
Affinity Capture-MS Homo sapiens
467 RLIM 51132
Affinity Capture-MS Homo sapiens
468 Rrbp1  
Affinity Capture-MS Mus musculus
469 RPL3 6122
Affinity Capture-MS Homo sapiens
470 ETF1 2107
Cross-Linking-MS (XL-MS) Homo sapiens
471 RPL7 6129
Co-fractionation Homo sapiens
472 SART1 9092
Affinity Capture-MS Homo sapiens
473 ZC3H10  
Affinity Capture-MS Homo sapiens
474 AURKB 9212
Affinity Capture-MS Homo sapiens
475 JUN 3725
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
476 PSTPIP1 9051
Affinity Capture-MS Homo sapiens
477 GLYR1 84656
Affinity Capture-MS Homo sapiens
478 IL7R  
Protein-RNA Homo sapiens
479 DKC1 1736
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
480 FBXO6 26270
Affinity Capture-MS Homo sapiens
481 INO80B 83444
Affinity Capture-MS Homo sapiens
482 VDAC1 7416
Affinity Capture-MS Homo sapiens
483 ZC3H3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
484 EIF3M 10480
Affinity Capture-MS Homo sapiens
485 CCDC8  
Affinity Capture-MS Homo sapiens
486 H2AFX 3014
Reconstituted Complex Homo sapiens
487 YTHDC2 64848
Affinity Capture-MS Homo sapiens
488 MAPKAPK2 9261
Affinity Capture-MS Homo sapiens
489 ZNF689  
Affinity Capture-MS Homo sapiens
490 SRRM1 10250
Affinity Capture-MS Homo sapiens
491 ERH 2079
Affinity Capture-MS Homo sapiens
492 MNDA 4332
Affinity Capture-MS Homo sapiens
493 ZNF746  
Affinity Capture-MS Homo sapiens
494 SAP18 10284
Co-fractionation Homo sapiens
495 HNRNPA2B1 3181
Affinity Capture-MS Homo sapiens
496 SMNDC1  
Affinity Capture-MS Homo sapiens
497 SMURF1 57154
Affinity Capture-MS Homo sapiens
498 ZNF48  
Affinity Capture-MS Homo sapiens
499 RPS15 6209
Affinity Capture-MS Homo sapiens
500 ELAVL1 1994
Affinity Capture-MS Homo sapiens
501 NSA2  
Affinity Capture-MS Homo sapiens
502 HDGF 3068
Affinity Capture-MS Homo sapiens
503 Mta1  
Affinity Capture-MS Mus musculus
504 RBFOX2 23543
Two-hybrid Homo sapiens
505 RBM4 5936
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
506 TERF1 7013
Two-hybrid Homo sapiens
507 MOV10 4343
Affinity Capture-MS Homo sapiens
508 TRIP4 9325
Affinity Capture-MS Homo sapiens
509 IBTK 25998
Affinity Capture-MS Homo sapiens
510 SRSF7 6432
Co-fractionation Homo sapiens
511 PINK1  
Affinity Capture-MS Homo sapiens
512 RPS6 6194
Affinity Capture-MS Homo sapiens
513 GRSF1 2926
Proximity Label-MS Homo sapiens
514 ZNF629 23361
Affinity Capture-MS Homo sapiens
515 DNAJC1 64215
Affinity Capture-MS Homo sapiens
516 HNRNPU 3192
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
517 C9orf72  
Affinity Capture-MS Homo sapiens
518 IVNS1ABP  
Affinity Capture-MS Homo sapiens
519 STRBP 55342
Affinity Capture-MS Homo sapiens
520 RPL17 6139
Affinity Capture-MS Homo sapiens
521 CDC5L 988
Affinity Capture-MS Homo sapiens
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Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here