Gene ontology annotations for LYAR
Experiment description of studies that identified LYAR in exosomes
1
Experiment ID
207
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|HSP70
EV Cytosolic markers
✔
FLOT1
EV Membrane markers
✔
VDAC
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23161513
Organism
Homo sapiens
Experiment description
Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors
Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ.
Journal name
Mol Cell Proteomics
Publication year
2012
Sample
Colorectal cancer cells
Sample name
DKO-1
Isolation/purification methods
Differential centrifugation Filtration
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
2
Experiment ID
208
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|HSP70
EV Cytosolic markers
✔
FLOT1
EV Membrane markers
✔
VDAC
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23161513
Organism
Homo sapiens
Experiment description
Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors
Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ.
Journal name
Mol Cell Proteomics
Publication year
2012
Sample
Colorectal cancer cells
Sample name
Dks-8
Isolation/purification methods
Differential centrifugation Filtration
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
3
Experiment ID
209
ISEV standards
✘
EV Biophysical techniques
✔
TSG101|HSP70
EV Cytosolic markers
✔
FLOT1
EV Membrane markers
✔
VDAC
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23161513
Organism
Homo sapiens
Experiment description
Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors
Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ.
Journal name
Mol Cell Proteomics
Publication year
2012
Sample
Colorectal cancer cells
Sample name
DLD-1
Isolation/purification methods
Differential centrifugation Filtration
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
4
Experiment ID
257
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101
EV Cytosolic markers
✔
FLOT1
EV Membrane markers
✘
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25950383
Organism
Homo sapiens
Experiment description
Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors
Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L
Journal name
Pigment Cell Melanoma Res
Publication year
2015
Sample
Melanoma cells
Sample name
Daju
Isolation/purification methods
Differential centrifugation Unltracentrifugation Sucrose density gradient
Flotation density
1.13 - 1.19 g/mL
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
5
Experiment ID
126
ISEV standards
✘
EV Biophysical techniques
✔
GAPDH
EV Cytosolic markers
✘
EV Membrane markers
✘
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry [LTQ-FT Ultra]
PubMed ID
Unpublished / Not applicable
Organism
Homo sapiens
Experiment description
Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors
Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim
Journal name
Mesenchymal Stem Cell Therapy
Publication year
2011
Sample
Mesenchymal stem cells
Sample name
huES9.E1
Isolation/purification methods
HPLC
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Antobody array Mass spectrometry
Protein-protein interactions for LYAR
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
GNL2
29889
Affinity Capture-MS
Homo sapiens
2
TWF2
11344
Affinity Capture-MS
Homo sapiens
3
DHX57
Affinity Capture-MS
Homo sapiens
4
RPS3A
6189
Affinity Capture-MS
Homo sapiens
5
KPNA1
3836
Affinity Capture-MS
Homo sapiens
6
ZHX1
Two-hybrid
Homo sapiens
7
EIF3I
8668
Affinity Capture-MS
Homo sapiens
8
BRIX1
55299
Affinity Capture-MS
Homo sapiens
9
KRTHB2
Affinity Capture-MS
Homo sapiens
10
NAT10
55226
Affinity Capture-MS
Homo sapiens
11
DDX21
9188
Affinity Capture-MS
Homo sapiens
12
RPL21
6144
Affinity Capture-MS
Homo sapiens
13
RPL3
6122
Affinity Capture-MS
Homo sapiens
14
EBNA1BP2
10969
Affinity Capture-MS
Homo sapiens
15
ZBTB16
Two-hybrid
Homo sapiens
16
RPS9
Affinity Capture-MS
Homo sapiens
17
RPL18A
6142
Affinity Capture-MS
Homo sapiens
18
RPL31
6160
Affinity Capture-MS
Homo sapiens
19
RPL23A
6147
Affinity Capture-MS
Homo sapiens
20
NPM1
4869
Affinity Capture-MS
Homo sapiens
21
DHX9
1660
Affinity Capture-MS
Homo sapiens
22
TSR1
55720
Affinity Capture-MS
Homo sapiens
23
SRP14
6727
Affinity Capture-MS
Homo sapiens
24
KRT31
3881
Affinity Capture-MS
Homo sapiens
25
MYBBP1A
10514
Affinity Capture-MS
Homo sapiens
26
DDX27
55661
Affinity Capture-MS
Homo sapiens
27
GTPBP4
23560
Affinity Capture-MS
Homo sapiens
28
KRTHB5
Affinity Capture-MS
Homo sapiens
View the network
image/svg+xml
Pathways in which LYAR is involved
No pathways found