Gene description for NOL12
Gene name nucleolar protein 12
Gene symbol NOL12
Other names/aliases Nop25
Species Homo sapiens
 Database cross references - NOL12
ExoCarta ExoCarta_79159
Entrez Gene 79159
HGNC 28585
UniProt Q9UGY1  
 NOL12 identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for NOL12
Molecular Function
    poly(A) RNA binding GO:0044822 IDA
    rRNA binding GO:0019843 IEA
    protein binding GO:0005515 IPI
Subcellular Localization
    nucleolus GO:0005730 IEA
 Experiment description of studies that identified NOL12 in exosomes
Experiment ID 237
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for NOL12
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SOD2 6648
Two-hybrid Homo sapiens
2 SAP18 10284
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which NOL12 is involved
No pathways found

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