Gene description for GPATCH4
Gene name G patch domain containing 4
Gene symbol GPATCH4
Other names/aliases GPATC4
Species Homo sapiens
 Database cross references - GPATCH4
ExoCarta ExoCarta_54865
Vesiclepedia VP_54865
Entrez Gene 54865
HGNC 25982
 GPATCH4 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for GPATCH4
Molecular Function
    RNA binding GO:0003723 HDA
    protein binding GO:0005515 IPI
Subcellular Localization
    nucleolus GO:0005730 IBA
 Experiment description of studies that identified GPATCH4 in exosomes
1
Experiment ID 236
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for GPATCH4
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 GNL2 29889
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
2 UBE2H 7328
Affinity Capture-MS Homo sapiens
3 NOP14 8602
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 RPSAP58 388524
Affinity Capture-MS Homo sapiens
5 H1FNT  
Affinity Capture-MS Homo sapiens
6 HIST2H2AB 317772
Affinity Capture-MS Homo sapiens
7 ZNF771  
Affinity Capture-MS Homo sapiens
8 COIL  
Proximity Label-MS Homo sapiens
9 PAXIP1  
Affinity Capture-MS Homo sapiens
10 RPS3A 6189
Affinity Capture-MS Homo sapiens
11 KLF9 687
Proximity Label-MS Homo sapiens
12 TOP2B 7155
Affinity Capture-MS Homo sapiens
13 ZNF668  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
14 ZCCHC9  
Affinity Capture-MS Homo sapiens
15 PRPF38A 84950
Affinity Capture-MS Homo sapiens
16 RPL37A 6168
Affinity Capture-MS Homo sapiens
17 NOP56 10528
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
18 DHX8 1659
Proximity Label-MS Homo sapiens
19 RPL26L1 51121
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
20 RPL10 6134
Affinity Capture-MS Homo sapiens
21 RPL15 6138
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
22 BRD2  
Affinity Capture-MS Homo sapiens
23 RPL14 9045
Affinity Capture-MS Homo sapiens
24 BUD13  
Affinity Capture-MS Homo sapiens
25 ZNF92  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
26 RBM34  
Affinity Capture-MS Homo sapiens
27 PWP2 5822
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
28 CENPA  
Proximity Label-MS Homo sapiens
29 APEX1 328
Affinity Capture-RNA Homo sapiens
Proximity Label-MS Homo sapiens
30 DDX23 9416
Proximity Label-MS Homo sapiens
31 RPL10A 4736
Affinity Capture-MS Homo sapiens
32 MYEF2 50804
Affinity Capture-MS Homo sapiens
33 PRR11  
Affinity Capture-MS Homo sapiens
34 WHSC1 7468
Affinity Capture-MS Homo sapiens
35 CEP70  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
36 KLF8  
Affinity Capture-MS Homo sapiens
37 DDX24 57062
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
38 CCDC137  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
39 RRP12 23223
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 FBXW7  
Affinity Capture-MS Homo sapiens
41 NPM1 4869
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
42 FBL 2091
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
43 POLR1E  
Proximity Label-MS Homo sapiens
44 SPTY2D1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
45 RPF2 84154
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
46 TTF1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
47 STAU2 27067
Affinity Capture-MS Homo sapiens
48 Nhp2l1 20826
Affinity Capture-MS Mus musculus
49 BRD4 23476
Affinity Capture-MS Homo sapiens
50 SLX4  
Affinity Capture-MS Homo sapiens
51 NOC3L 64318
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
52 RRP8  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
53 CUL1 8454
Affinity Capture-MS Homo sapiens
54 MYCN  
Affinity Capture-MS Homo sapiens
55 STAU1 6780
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
56 ADARB2  
Affinity Capture-MS Homo sapiens
57 MAK16  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
58 NEIL3  
Affinity Capture-MS Homo sapiens
59 KIF14 9928
Affinity Capture-MS Homo sapiens
60 GAR1 54433
Affinity Capture-MS Homo sapiens
61 FCF1  
Affinity Capture-MS Homo sapiens
62 SAMHD1 25939
Affinity Capture-MS Homo sapiens
63 KLF16  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
64 DDX31  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
65 KIAA0020 9933
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
66 MYB  
Proximity Label-MS Homo sapiens
67 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
68 DDX21 9188
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
69 RPL4 6124
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
70 RBM28 55131
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
71 Rock1  
Affinity Capture-MS Mus musculus
72 TARBP2  
Affinity Capture-MS Homo sapiens
73 RRP9 9136
Affinity Capture-MS Homo sapiens
74 RBM4B  
Affinity Capture-MS Homo sapiens
75 GZF1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
76 NOP2 4839
Affinity Capture-MS Homo sapiens
77 CBX3 11335
Proximity Label-MS Homo sapiens
78 HIST1H2AM 8336
Affinity Capture-MS Homo sapiens
79 RPL18A 6142
Affinity Capture-MS Homo sapiens
80 NTRK1 4914
Affinity Capture-MS Homo sapiens
81 RPL31 6160
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
82 IFI16 3428
Affinity Capture-MS Homo sapiens
83 ZNF354A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
84 Emc6  
Affinity Capture-MS Mus musculus
85 RBMX2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
86 RPL36 25873
Affinity Capture-MS Homo sapiens
87 HIST1H2BG 8339
Proximity Label-MS Homo sapiens
88 LYAR 55646
Affinity Capture-MS Homo sapiens
89 HECTD1 25831
Affinity Capture-MS Homo sapiens
90 RPLP0 6175
Affinity Capture-MS Homo sapiens
91 MAGEB2 4113
Affinity Capture-MS Homo sapiens
92 MYBBP1A 10514
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
93 DDX27 55661
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
94 GTPBP4 23560
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
95 DAXX  
Affinity Capture-MS Homo sapiens
96 OGT 8473
Reconstituted Complex Homo sapiens
97 CD3EAP  
Proximity Label-MS Homo sapiens
98 DDAH2 23564
Affinity Capture-MS Homo sapiens
99 RSL1D1 26156
Affinity Capture-MS Homo sapiens
100 SCARNA22  
Affinity Capture-RNA Homo sapiens
101 FGFBP1 9982
Affinity Capture-MS Homo sapiens
102 PPAN-P2RY11  
Affinity Capture-MS Homo sapiens
103 Cdkn2aip  
Affinity Capture-MS Mus musculus
104 RPL32 6161
Affinity Capture-MS Homo sapiens
105 ZBTB2 57621
Affinity Capture-MS Homo sapiens
106 CRKL 1399
Affinity Capture-MS Homo sapiens
107 HIST1H3A 8350
Proximity Label-MS Homo sapiens
108 ABT1 29777
Affinity Capture-MS Homo sapiens
109 POP1 10940
Affinity Capture-MS Homo sapiens
110 EIF6 3692
Proximity Label-MS Homo sapiens
111 RC3H2  
Affinity Capture-MS Homo sapiens
112 ECT2 1894
Affinity Capture-MS Homo sapiens
113 ZNF701  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
114 RPL35 11224
Affinity Capture-MS Homo sapiens
115 NOC4L 79050
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
116 NAT10 55226
Affinity Capture-MS Homo sapiens
117 PCDHB15  
Affinity Capture-MS Homo sapiens
118 SRSF1 6426
Affinity Capture-MS Homo sapiens
119 ZNF624 57547
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
120 CUL3 8452
Affinity Capture-MS Homo sapiens
121 RPS6 6194
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
122 RPL3 6122
Affinity Capture-MS Homo sapiens
123 EBNA1BP2 10969
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
124 PAPD5 64282
Affinity Capture-MS Homo sapiens
125 CCDC155  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
126 DHX30 22907
Affinity Capture-MS Homo sapiens
127 BBX 56987
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
128 ZC3H10  
Affinity Capture-MS Homo sapiens
129 Vps4b 20479
Affinity Capture-MS Mus musculus
130 ZNF512  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
131 LRPAP1 4043
Affinity Capture-MS Homo sapiens
132 DKC1 1736
Affinity Capture-MS Homo sapiens
133 MYC  
Affinity Capture-MS Homo sapiens
134 RPA3 6119
Proximity Label-MS Homo sapiens
135 NLRP3  
Affinity Capture-MS Homo sapiens
136 CEBPZ  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
137 Mis12  
Affinity Capture-MS Mus musculus
138 NOL12 79159
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
139 RBM19 9904
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
140 RPA4  
Proximity Label-MS Homo sapiens
141 HP1BP3 50809
Affinity Capture-MS Homo sapiens
142 HIST1H1A 3024
Affinity Capture-MS Homo sapiens
143 RPL7L1 285855
Affinity Capture-MS Homo sapiens
144 DDRGK1 65992
Affinity Capture-MS Homo sapiens
145 RNF2  
Affinity Capture-MS Homo sapiens
146 ZC3HAV1 56829
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
147 ZFP62  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
148 LMNA 4000
Proximity Label-MS Homo sapiens
149 DDX52  
Affinity Capture-MS Homo sapiens
150 FTSJ3 117246
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
151 RPL11 6135
Affinity Capture-MS Homo sapiens
152 NGDN  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
153 C3orf17  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
154 NES 10763
Affinity Capture-MS Homo sapiens
155 RPL13 6137
Affinity Capture-MS Homo sapiens
156 SURF6  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
157 FASN 2194
Positive Genetic Homo sapiens
158 FYTTD1  
Affinity Capture-MS Homo sapiens
159 RNF151  
Affinity Capture-MS Homo sapiens
160 PARP1 142
Proximity Label-MS Homo sapiens
161 FBXL6  
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
162 RRS1 23212
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
163 CIT 11113
Affinity Capture-MS Homo sapiens
164 PRDM15  
Affinity Capture-MS Homo sapiens
165 NLE1 54475
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
166 MNDA 4332
Affinity Capture-MS Homo sapiens
167 USP36  
Affinity Capture-MS Homo sapiens
168 DGCR8  
Affinity Capture-MS Homo sapiens
169 UTP23  
Affinity Capture-MS Homo sapiens
170 NSA2  
Affinity Capture-MS Homo sapiens
171 MFAP1  
Affinity Capture-MS Homo sapiens
172 MKI67  
Affinity Capture-MS Homo sapiens
173 NIFK 84365
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
174 BRIX1 55299
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
175 DHX40  
Proximity Label-MS Homo sapiens
176 NUP50 10762
Proximity Label-MS Homo sapiens
177 RPS24 6229
Proximity Label-MS Homo sapiens
178 SP100 6672
Affinity Capture-MS Homo sapiens
179 RPL30 6156
Affinity Capture-MS Homo sapiens
180 TRIP4 9325
Affinity Capture-MS Homo sapiens
181 RPL7A 6130
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
182 NUFIP1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
183 RPS8 6202
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
184 GRSF1 2926
Proximity Label-MS Homo sapiens
185 GLYR1 84656
Affinity Capture-MS Homo sapiens
186 OAZ1 4946
Affinity Capture-MS Homo sapiens
187 NMNAT1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
188 ZNF845  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
189 RC3H1 149041
Affinity Capture-MS Homo sapiens
190 NVL  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
191 DDX56  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
192 HERC5 51191
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
193 NHLH1  
Proximity Label-MS Homo sapiens
View the network image/svg+xml
 Pathways in which GPATCH4 is involved
No pathways found





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