Gene description for Nhp2l1
Gene name NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)
Gene symbol Nhp2l1
Other names/aliases FA-1
Fta1
Ssfa1
Species Mus musculus
 Database cross references - Nhp2l1
ExoCarta ExoCarta_20826
Entrez Gene 20826
UniProt Q9D0T1  
 Nhp2l1 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Nhp2l1
Molecular Function
    box C/D snoRNA binding GO:0034512 ISO
    U3 snoRNA binding GO:0034511 ISO
    poly(A) RNA binding GO:0044822 ISO
    U4 snRNA binding GO:0030621 ISO
    snoRNA binding GO:0030515 ISO
Biological Process
    single fertilization GO:0007338 IDA
Subcellular Localization
    box C/D snoRNP complex GO:0031428 ISO
    plasma membrane GO:0005886 ISS
    protein complex GO:0043234 ISO
 Experiment description of studies that identified Nhp2l1 in exosomes
1
Experiment ID 15
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Nhp2l1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Nhp2l1 is involved
PathwayEvidenceSource
mRNA Splicing - Major Pathway IEA Reactome
mRNA Splicing - Minor Pathway IEA Reactome





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