Gene description for KPNA1
Gene name karyopherin alpha 1 (importin alpha 5)
Gene symbol KPNA1
Other names/aliases IPOA5
NPI-1
RCH2
SRP1
Species Homo sapiens
 Database cross references - KPNA1
ExoCarta ExoCarta_3836
Vesiclepedia VP_3836
Entrez Gene 3836
HGNC 6394
MIM 600686
UniProt P52294  
 KPNA1 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Colorectal cancer cells 34887515    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
Thymus 23844026    
 Gene ontology annotations for KPNA1
Molecular Function
    protein binding GO:0005515 IPI
    nuclear localization sequence binding GO:0008139 IBA
    nuclear import signal receptor activity GO:0061608 IBA
    nuclear import signal receptor activity GO:0061608 IDA
Biological Process
    regulation of DNA recombination GO:0000018 TAS
    protein import into nucleus GO:0006606 ISS
    NLS-bearing protein import into nucleus GO:0006607 IBA
    NLS-bearing protein import into nucleus GO:0006607 IDA
    skeletal muscle satellite cell proliferation GO:0014841 IEA
    satellite cell activation involved in skeletal muscle regeneration GO:0014901 IEA
    regulation of apoptotic process GO:0042981 IEA
    regulation of canonical Wnt signaling pathway GO:0060828 IEA
    postsynapse to nucleus signaling pathway GO:0099527 IBA
Subcellular Localization
    nucleus GO:0005634 IBA
    nucleus GO:0005634 ISS
    nuclear pore GO:0005643 TAS
    nucleoplasm GO:0005654 IBA
    nucleoplasm GO:0005654 IDA
    nucleoplasm GO:0005654 IDA
    nucleoplasm GO:0005654 NAS
    nucleoplasm GO:0005654 TAS
    cytoplasm GO:0005737 TAS
    cytosol GO:0005829 IDA
    cytosol GO:0005829 IDA
    cytosol GO:0005829 NAS
    cytosol GO:0005829 TAS
    postsynaptic density GO:0014069 IEA
    dendrite GO:0030425 ISS
    NLS-dependent protein nuclear import complex GO:0042564 IPI
    glutamatergic synapse GO:0098978 IEA
 Experiment description of studies that identified KPNA1 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
6
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
7
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
9
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
10
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
11
Experiment ID 834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
13
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for KPNA1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 UBE2H 7328
Affinity Capture-MS Homo sapiens
2 CCAR1 55749
Affinity Capture-MS Homo sapiens
3 NAF1  
Affinity Capture-MS Homo sapiens
4 CDCA2 157313
Affinity Capture-MS Homo sapiens
5 HNRNPC 3183
Affinity Capture-MS Homo sapiens
6 SLIT2 9353
Affinity Capture-MS Homo sapiens
7 GATAD2B 57459
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 SPRTN  
Affinity Capture-MS Homo sapiens
9 NOP58 51602
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 ORC4  
Two-hybrid Homo sapiens
11 MACROD1 28992
Two-hybrid Homo sapiens
12 COIL  
Proximity Label-MS Homo sapiens
13 ANP32A 8125
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
14 PTMA 5757
Affinity Capture-MS Homo sapiens
15 THRB 7068
Affinity Capture-Western Homo sapiens
16 PKM 5315
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
17 TADA3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
18 NKRF 55922
Affinity Capture-MS Homo sapiens
19 KIAA2013 90231
Affinity Capture-MS Homo sapiens
20 NUP62 23636
Reconstituted Complex Homo sapiens
21 KPNB1 3837
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
22 SUB1 10923
Co-fractionation Homo sapiens
23 CTNNBL1 56259
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
24 NOP56 10528
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
25 NMNAT1  
Two-hybrid Homo sapiens
26 RPS19 6223
Co-fractionation Homo sapiens
27 SMARCE1 6605
Affinity Capture-MS Homo sapiens
28 TRIM33 51592
Affinity Capture-MS Homo sapiens
29 RNMT 8731
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
30 RBM45  
Affinity Capture-MS Homo sapiens
31 CSE1L 1434
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
32 XRN2 22803
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
33 KPNA2 3838
Co-fractionation Homo sapiens
34 CAND1 55832
Affinity Capture-MS Homo sapiens
35 PDCD11 22984
Affinity Capture-MS Homo sapiens
36 NIPBL 25836
Affinity Capture-MS Homo sapiens
37 SMARCD2 6603
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
38 EPC1  
Affinity Capture-MS Homo sapiens
39 RNGTT 8732
Affinity Capture-MS Homo sapiens
40 JRK  
Affinity Capture-MS Homo sapiens
41 IL1RAP 3556
Two-hybrid Homo sapiens
42 APEX1 328
Affinity Capture-RNA Homo sapiens
43 NOL8  
Affinity Capture-MS Homo sapiens
44 PSIP1 11168
Affinity Capture-MS Homo sapiens
45 TOP2A 7153
Co-fractionation Homo sapiens
46 RUVBL1 8607
Affinity Capture-MS Homo sapiens
47 NCOR1  
Affinity Capture-MS Homo sapiens
48 ZFHX4  
Affinity Capture-MS Homo sapiens
49 TAF9 6880
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
50 VPS72  
Affinity Capture-MS Homo sapiens
51 MCM2 4171
Affinity Capture-MS Homo sapiens
52 CTDSPL2  
Affinity Capture-MS Homo sapiens
53 KPNA3 3839
Co-fractionation Homo sapiens
54 SF3B1 23451
Affinity Capture-MS Homo sapiens
55 NUP153 9972
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
56 CDK2AP1  
Affinity Capture-MS Homo sapiens
57 ANP32B 10541
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
58 COPS5 10987
Affinity Capture-MS Homo sapiens
59 ING3  
Affinity Capture-MS Homo sapiens
60 ZNF148  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
61 NPM1 4869
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
62 FBXO28  
Affinity Capture-MS Homo sapiens
63 CRADD  
Two-hybrid Homo sapiens
64 FBL 2091
Co-fractionation Homo sapiens
65 POLR1E  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
66 BOD1L1 259282
Affinity Capture-MS Homo sapiens
67 PAK1IP1  
Affinity Capture-MS Homo sapiens
68 FANCD2  
Co-fractionation Homo sapiens
69 ILF3 3609
Affinity Capture-MS Homo sapiens
70 GOPC 57120
Two-hybrid Homo sapiens
71 Nhp2l1 20826
Affinity Capture-MS Mus musculus
72 UTP20 27340
Affinity Capture-MS Homo sapiens
73 CUL1 8454
Affinity Capture-MS Homo sapiens
74 BTRC 8945
Affinity Capture-MS Homo sapiens
75 CPT2 1376
Co-fractionation Homo sapiens
76 SMARCA1 6594
Affinity Capture-MS Homo sapiens
77 ZNHIT6 54680
Affinity Capture-MS Homo sapiens
78 BCAR3 8412
Two-hybrid Homo sapiens
79 BCL7B  
Affinity Capture-MS Homo sapiens
80 LMO4  
Two-hybrid Homo sapiens
81 MTA1 9112
Affinity Capture-MS Homo sapiens
82 TP53BP1 7158
Affinity Capture-MS Homo sapiens
83 TAF5L  
Affinity Capture-MS Homo sapiens
84 FAS 355
Proximity Label-MS Homo sapiens
85 TRIM59  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
86 TRRAP 8295
Affinity Capture-MS Homo sapiens
87 NUP155 9631
Proximity Label-MS Homo sapiens
88 H2AFZ 3015
Affinity Capture-MS Homo sapiens
89 DHX40  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
90 PHF10  
Affinity Capture-MS Homo sapiens
91 CDKN2AIP  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
92 SMARCD1 6602
Affinity Capture-MS Homo sapiens
93 CLK4  
Two-hybrid Homo sapiens
94 TSSC4  
Affinity Capture-MS Homo sapiens
95 SENP2 59343
Reconstituted Complex Homo sapiens
96 LMNA 4000
Co-fractionation Homo sapiens
97 DDX21 9188
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
98 CUL4B 8450
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
99 MEPCE 56257
Affinity Capture-MS Homo sapiens
100 PHAX  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
101 SUPT7L  
Affinity Capture-MS Homo sapiens
102 TGS1  
Affinity Capture-MS Homo sapiens
103 ZMYM1 79830
Affinity Capture-MS Homo sapiens
104 TRMT61A 115708
Co-fractionation Homo sapiens
105 TAF9B  
Affinity Capture-MS Homo sapiens
106 SMARCA4 6597
Affinity Capture-MS Homo sapiens
107 RAG1  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
108 CDKN2AIPNL  
Affinity Capture-MS Homo sapiens
109 SRBD1  
Affinity Capture-MS Homo sapiens
110 UBR5 51366
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
111 Ddx21 56200
Affinity Capture-MS Mus musculus
112 NTRK1 4914
Affinity Capture-MS Homo sapiens
113 GIT1 28964
Affinity Capture-MS Homo sapiens
114 Mki67 17345
Affinity Capture-MS Mus musculus
115 BPTF 2186
Affinity Capture-MS Homo sapiens
116 DTX2 113878
Proximity Label-MS Homo sapiens
117 BEND7 222389
Affinity Capture-MS Homo sapiens
118 SUPT3H  
Affinity Capture-MS Homo sapiens
119 TULP3 7289
Affinity Capture-MS Homo sapiens
120 MBD2 8932
Affinity Capture-MS Homo sapiens
121 CRY2  
Affinity Capture-MS Homo sapiens
122 LYAR 55646
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
123 SDAD1  
Affinity Capture-MS Homo sapiens
124 MBD3 53615
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
125 SRPK3  
Affinity Capture-MS Homo sapiens
126 KPNA5 3841
Affinity Capture-MS Homo sapiens
127 PRPF31 26121
Affinity Capture-Western Homo sapiens
128 LIMCH1 22998
Co-fractionation Homo sapiens
129 HUWE1 10075
Affinity Capture-MS Homo sapiens
130 STAG2 10735
Affinity Capture-MS Homo sapiens
131 HIF1A 3091
Affinity Capture-Western Homo sapiens
132 GPATCH11  
Affinity Capture-MS Homo sapiens
133 GNL3L 54552
Two-hybrid Homo sapiens
134 OGT 8473
Reconstituted Complex Homo sapiens
135 RAN 5901
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
136 CD3EAP  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
137 ZCCHC8 55596
Affinity Capture-MS Homo sapiens
138 C16orf72 29035
Affinity Capture-MS Homo sapiens
139 TPX2  
Affinity Capture-Western Homo sapiens
140 BRD7  
Affinity Capture-MS Homo sapiens
141 PRKCZ 5590
Affinity Capture-Western Homo sapiens
142 SLX4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
143 WDR48 57599
Affinity Capture-MS Homo sapiens
144 GPT 2875
Affinity Capture-MS Homo sapiens
145 ESF1 51575
Affinity Capture-MS Homo sapiens
146 IPO5 3843
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
147 SF1 7536
Two-hybrid Homo sapiens
148 NR4A1  
Affinity Capture-MS Homo sapiens
149 SKP2  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
150 CLK3  
Affinity Capture-MS Homo sapiens
151 BAZ1B 9031
Affinity Capture-MS Homo sapiens
152 C9orf78 51759
Affinity Capture-MS Homo sapiens
153 LMNB1 4001
Two-hybrid Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
154 NCBP2 22916
Affinity Capture-MS Homo sapiens
155 SMARCA5 8467
Affinity Capture-MS Homo sapiens
156 RELA 5970
Affinity Capture-Western Homo sapiens
157 CD2BP2 10421
Affinity Capture-MS Homo sapiens
158 PLRG1 5356
Affinity Capture-Western Homo sapiens
159 HDAC2 3066
Affinity Capture-MS Homo sapiens
160 KCTD12 115207
Co-fractionation Homo sapiens
161 CTCF  
Co-fractionation Homo sapiens
162 CUL3 8452
Affinity Capture-MS Homo sapiens
163 NR3C1 2908
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
164 YLPM1 56252
Affinity Capture-MS Homo sapiens
165 ERCC4  
Affinity Capture-MS Homo sapiens
166 CSNK2A1 1457
Affinity Capture-MS Homo sapiens
167 SEPT9 10801
Affinity Capture-Western Homo sapiens
168 C12orf45  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
169 ADNP 23394
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
170 BAP1 8314
Protein-peptide Homo sapiens
171 MORF4L1  
Co-fractionation Homo sapiens
172 ANP32E 81611
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
173 RBBP4 5928
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
174 THRA  
Affinity Capture-Western Homo sapiens
175 DCAF8 50717
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
176 PHB2 11331
Affinity Capture-Western Homo sapiens
177 RUNX1T1  
Reconstituted Complex Homo sapiens
178 DCAF6 55827
Co-fractionation Homo sapiens
179 MAU2  
Affinity Capture-MS Homo sapiens
180 STAT1 6772
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
181 PRPF19 27339
Affinity Capture-Western Homo sapiens
182 HECW2  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
183 EP400  
Affinity Capture-MS Homo sapiens
184 CECR2  
Affinity Capture-MS Homo sapiens
185 DIS3 22894
Affinity Capture-MS Homo sapiens
186 USP7 7874
Affinity Capture-MS Homo sapiens
187 NCBP1 4686
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
188 TRIM27  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
189 KAT5  
Affinity Capture-MS Homo sapiens
190 ATM 472
Two-hybrid Homo sapiens
191 BAZ1A 11177
Affinity Capture-MS Homo sapiens
192 CHD8 57680
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
193 SMARCA2 6595
Affinity Capture-MS Homo sapiens
194 MEAF6  
Affinity Capture-MS Homo sapiens
195 HSPA4 3308
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
196 STYX  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
197 GMCL1  
Affinity Capture-MS Homo sapiens
198 CDKN1B 1027
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
199 UHRF1 29128
Affinity Capture-MS Homo sapiens
200 TADA2B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
201 KAT2A  
Affinity Capture-MS Homo sapiens
202 ALKBH5 54890
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
203 MDM2  
Reconstituted Complex Homo sapiens
204 Nipbl  
Affinity Capture-MS Mus musculus
205 DDX55  
Affinity Capture-MS Homo sapiens
206 FAM103A1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
207 MTA2 9219
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
208 GATAD2A 54815
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
209 ARHGEF7 8874
Affinity Capture-MS Homo sapiens
210 NOSIP 51070
Reconstituted Complex Homo sapiens
211 EXOSC10 5394
Cross-Linking-MS (XL-MS) Homo sapiens
212 CPSF3L 54973
Affinity Capture-MS Homo sapiens
213 NUP54 53371
Reconstituted Complex Homo sapiens
214 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
215 FBXW11  
Affinity Capture-MS Homo sapiens
216 SPOP  
Affinity Capture-MS Homo sapiens
217 SIRT6  
Affinity Capture-MS Homo sapiens
218 PARP1 142
Co-fractionation Homo sapiens
219 BKRF1  
Affinity Capture-MS
220 ARID2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
221 SUPT20H 55578
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
222 POLR1B 84172
Affinity Capture-MS Homo sapiens
223 USP1 7398
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
224 RUVBL2 10856
Affinity Capture-MS Homo sapiens
225 INTS9 55756
Affinity Capture-MS Homo sapiens
226 FOSL1  
Two-hybrid Homo sapiens
227 POLR3C 10623
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
228 HDAC6 10013
Reconstituted Complex Homo sapiens
229 ADNP2  
Affinity Capture-MS Homo sapiens
230 IKBKG 8517
Affinity Capture-Western Homo sapiens
231 KPNA6 23633
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
232 ERCC1  
Affinity Capture-MS Homo sapiens
233 TEX10 54881
Affinity Capture-MS Homo sapiens
234 AICDA  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
235 PBRM1 55193
Affinity Capture-MS Homo sapiens
236 MORF4L2  
Co-fractionation Homo sapiens
237 PTPN2 5771
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
238 HDAC1 3065
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
239 CHD4 1108
Affinity Capture-MS Homo sapiens
240 STRBP 55342
Affinity Capture-MS Homo sapiens
241 TCERG1 10915
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
242 KIF20B  
Affinity Capture-MS Homo sapiens
243 MKI67  
Affinity Capture-MS Homo sapiens
244 FAM122B  
Affinity Capture-MS Homo sapiens
245 UFL1 23376
Affinity Capture-MS Homo sapiens
246 NUP50 10762
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
247 GTPBP4 23560
Affinity Capture-MS Homo sapiens
248 FOXB1  
Affinity Capture-MS Homo sapiens
249 SREK1IP1  
Affinity Capture-MS Homo sapiens
250 DCLRE1A  
Affinity Capture-MS Homo sapiens
251 RAD21 5885
Affinity Capture-MS Homo sapiens
252 PAPSS1 9061
Affinity Capture-MS Homo sapiens
253 RANBP2 5903
Reconstituted Complex Homo sapiens
254 POLR3B 55703
Cross-Linking-MS (XL-MS) Homo sapiens
255 L3MBTL1  
Affinity Capture-MS Homo sapiens
256 DKC1 1736
Affinity Capture-MS Homo sapiens
257 MTA3 57504
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
258 SNW1 22938
Affinity Capture-MS Homo sapiens
259 HNRNPU 3192
Affinity Capture-MS Homo sapiens
260 C9orf72  
Affinity Capture-MS Homo sapiens
261 KBTBD4  
Affinity Capture-MS Homo sapiens
262 HMGXB4 10042
Affinity Capture-MS Homo sapiens
263 SMARCD3  
Affinity Capture-MS Homo sapiens
264 TAF12  
Affinity Capture-MS Homo sapiens
265 GABPA 2551
Co-fractionation Homo sapiens
266 FOXE1  
Affinity Capture-MS Homo sapiens
267 RPA3 6119
Proximity Label-MS Homo sapiens
268 NOP10 55505
Affinity Capture-MS Homo sapiens
269 WDHD1  
Affinity Capture-MS Homo sapiens
270 ARSF 416
Affinity Capture-MS Homo sapiens
271 CUL4A 8451
Affinity Capture-MS Homo sapiens
272 CHD3 1107
Affinity Capture-MS Homo sapiens
273 EPC2  
Affinity Capture-MS Homo sapiens
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Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here