Gene description for NUP62
Gene name nucleoporin 62kDa
Gene symbol NUP62
Other names/aliases IBSN
SNDI
p62
Species Homo sapiens
 Database cross references - NUP62
ExoCarta ExoCarta_23636
Vesiclepedia VP_23636
Entrez Gene 23636
HGNC 8066
MIM 605815
UniProt P37198  
 NUP62 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for NUP62
Molecular Function
    chromatin binding GO:0003682 NAS
    protein binding GO:0005515 IPI
    phospholipid binding GO:0005543 IBA
    structural constituent of nuclear pore GO:0017056 IBA
    signaling receptor complex adaptor activity GO:0030159 IDA
    Hsp70 protein binding GO:0030544 IEA
    SH2 domain binding GO:0042169 IDA
    ubiquitin binding GO:0043130 IDA
    PTB domain binding GO:0051425 IEA
    Hsp90 protein binding GO:0051879 IEA
Biological Process
    RNA export from nucleus GO:0006405 IBA
    protein import into nucleus GO:0006606 IBA
    nucleocytoplasmic transport GO:0006913 NAS
    mitotic metaphase chromosome alignment GO:0007080 IMP
    centrosome cycle GO:0007098 IMP
    mitotic centrosome separation GO:0007100 IMP
    cell surface receptor signaling pathway GO:0007166 IDA
    cell surface receptor signaling pathway GO:0007166 NAS
    negative regulation of cell population proliferation GO:0008285 IDA
    regulation of signal transduction GO:0009966 NAS
    negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 IEA
    negative regulation of apoptotic process GO:0043066 IDA
    negative regulation of programmed cell death GO:0043069 IDA
    positive regulation of canonical NF-kappaB signal transduction GO:0043123 IDA
    positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 NAS
    positive regulation of mitotic nuclear division GO:0045840 IMP
    positive regulation of DNA-templated transcription GO:0045893 IDA
    regulation of Ras protein signal transduction GO:0046578 NAS
    negative regulation of Ras protein signal transduction GO:0046580 IEA
    positive regulation of centriole replication GO:0046601 IMP
    mRNA transport GO:0051028 IEA
    regulation of mitotic spindle organization GO:0060236 IMP
    cellular senescence GO:0090398 IEA
    centriole assembly GO:0098534 IMP
    positive regulation of mitotic cytokinetic process GO:1903438 IMP
    positive regulation of protein localization to centrosome GO:1904781 IMP
Subcellular Localization
    spindle pole GO:0000922 IDA
    nuclear envelope GO:0005635 IDA
    nuclear envelope GO:0005635 TAS
    nuclear pore GO:0005643 IDA
    nuclear pore GO:0005643 NAS
    nucleoplasm GO:0005654 IDA
    cytoplasm GO:0005737 IDA
    cytoplasm GO:0005737 NAS
    centrosome GO:0005813 IDA
    nuclear membrane GO:0031965 IDA
    nuclear pore central transport channel GO:0044613 IBA
    mitotic spindle GO:0072686 IDA
    Flemming body GO:0090543 IDA
    ribonucleoprotein complex GO:1990904 IDA
 Experiment description of studies that identified NUP62 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 235
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for NUP62
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 FABP3 2170
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
2 SPATS2  
Affinity Capture-MS Homo sapiens
3 RIT1 6016
Negative Genetic Homo sapiens
4 MCM3 4172
Co-fractionation Homo sapiens
5 DPPA3  
Two-hybrid Homo sapiens
6 Hax1  
Affinity Capture-MS Mus musculus
7 PCK1 5105
Affinity Capture-MS Homo sapiens
8 BLOC1S6  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
9 KRT1 3848
Two-hybrid Homo sapiens
10 FAS 355
Proximity Label-MS Homo sapiens
11 CCDC150  
Two-hybrid Homo sapiens
12 KPNA1 3836
Reconstituted Complex Homo sapiens
13 KIFC3 3801
Two-hybrid Homo sapiens
14 KRT6A 3853
Two-hybrid Homo sapiens
15 TMED4 222068
Affinity Capture-MS Homo sapiens
16 SP1  
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
17 MYO15B 80022
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
18 NUP62 23636
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
19 KPNB1 3837
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
20 DISC1 27185
Affinity Capture-MS Homo sapiens
21 NUPL1 9818
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
22 SMARCE1 6605
Two-hybrid Homo sapiens
23 PHF21A  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
24 C17orf59 54785
Proximity Label-MS Homo sapiens
25 SYNE2 23224
Affinity Capture-MS Homo sapiens
26 KPNA2 3838
Two-hybrid Homo sapiens
27 FUBP3 8939
Co-fractionation Homo sapiens
28 KIF7 374654
Affinity Capture-MS Homo sapiens
29 NEFM 4741
Affinity Capture-MS Homo sapiens
30 ASXL1  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
31 NUP160 23279
Co-fractionation Homo sapiens
32 RNF40 9810
Affinity Capture-MS Homo sapiens
33 HSF2  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
34 APEX1 328
Affinity Capture-RNA Homo sapiens
35 KIAA1429 25962
Affinity Capture-MS Homo sapiens
36 LMO2  
Two-hybrid Homo sapiens
37 AGR3 155465
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
38 CENPU  
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
39 RNF20 56254
Affinity Capture-MS Homo sapiens
40 VTI1B 10490
Affinity Capture-MS Homo sapiens
41 USO1 8615
Affinity Capture-MS Homo sapiens
42 PRKCDBP 112464
Two-hybrid Homo sapiens
43 KLHL32 114792
Two-hybrid Homo sapiens
44 CEP57L1  
Two-hybrid Homo sapiens
45 MCM2 4171
Affinity Capture-MS Homo sapiens
46 KLC2 64837
Affinity Capture-MS Homo sapiens
47 NUP153 9972
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
48 KIF5B 3799
Affinity Capture-MS Homo sapiens
49 HGS 9146
Two-hybrid Homo sapiens
50 CCDC138  
Affinity Capture-MS Homo sapiens
51 MUC1 4582
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
52 ERC1 23085
Affinity Capture-MS Homo sapiens
53 NPM1 4869
Affinity Capture-Western Homo sapiens
54 STAT3 6774
Proximity Label-MS Homo sapiens
55 KIF5C 3800
Affinity Capture-MS Homo sapiens
56 CCDC53 51019
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
57 NUP93 9688
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
58 OIP5  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
59 KRT6B 3854
Two-hybrid Homo sapiens
60 OBSL1 23363
Affinity Capture-MS Homo sapiens
61 ARFIP2 23647
Two-hybrid Homo sapiens
62 XPO7 23039
Co-fractionation Homo sapiens
63 GOPC 57120
Two-hybrid Homo sapiens
64 TMTC4  
Affinity Capture-MS Homo sapiens
65 POLR2C 5432
Proximity Label-MS Homo sapiens
66 VPS53 55275
Affinity Capture-MS Homo sapiens
67 PKN3 29941
Affinity Capture-MS Homo sapiens
68 MYCN  
Affinity Capture-MS Homo sapiens
69 EXOC7 23265
Affinity Capture-MS Homo sapiens
70 COMMD4 54939
Affinity Capture-MS Homo sapiens
71 IFT20 90410
Two-hybrid Homo sapiens
72 C1orf216  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
73 KANSL1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
74 NUP155 9631
Proximity Label-MS Homo sapiens
75 Rab11fip1  
Affinity Capture-MS Mus musculus
76 PFN1 5216
Proximity Label-MS Homo sapiens
77 RAN 5901
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
78 KRT8 3856
Proximity Label-MS Homo sapiens
79 Nup188  
Affinity Capture-MS Mus musculus
80 AMOTL2 51421
Affinity Capture-MS Homo sapiens
81 PCNT  
Affinity Capture-MS Homo sapiens
82 CPNE2 221184
Affinity Capture-MS Homo sapiens
83 POLD1 5424
Affinity Capture-MS Homo sapiens
84 TRIML2  
Two-hybrid Homo sapiens
85 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
86 IKBIP 121457
Two-hybrid Homo sapiens
87 ISCU 23479
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
88 C9orf78 51759
Affinity Capture-MS Homo sapiens
89 PARK2  
Affinity Capture-MS Homo sapiens
90 VPS51 738
Affinity Capture-MS Homo sapiens
91 SDCCAG3  
Affinity Capture-MS Homo sapiens
92 KLC4 89953
Affinity Capture-MS Homo sapiens
93 MAPRE1 22919
Affinity Capture-MS Homo sapiens
94 ETV6  
Proximity Label-MS Homo sapiens
95 GOLGA2 2801
Affinity Capture-MS Homo sapiens
96 TRIM24  
Affinity Capture-MS Homo sapiens
97 COMMD8 54951
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
98 Nup88  
Affinity Capture-MS Mus musculus
99 OTUD6A  
Two-hybrid Homo sapiens
100 KIF5A 3798
Affinity Capture-MS Homo sapiens
101 SMTNL2  
Affinity Capture-MS Homo sapiens
102 SAFB2 9667
Cross-Linking-MS (XL-MS) Homo sapiens
103 VCP 7415
Affinity Capture-MS Homo sapiens
104 DTNB 1838
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
105 OGT 8473
Biochemical Activity Homo sapiens
Two-hybrid Homo sapiens
106 GORASP2 26003
Two-hybrid Homo sapiens
107 KRT75 9119
Two-hybrid Homo sapiens
108 FKBP15 23307
Affinity Capture-MS Homo sapiens
109 PEX14 5195
Proximity Label-MS Homo sapiens
110 MOGS 7841
Co-fractionation Homo sapiens
111 BICD2 23299
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
112 CCDC101  
Affinity Capture-MS Homo sapiens
113 CCDC22 28952
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
114 SDCCAG8  
Affinity Capture-MS Homo sapiens
115 CUX1 1523
Affinity Capture-MS Homo sapiens
116 COMMD3 23412
Affinity Capture-MS Homo sapiens
117 PDCD7  
Affinity Capture-MS Homo sapiens
118 SUOX  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
119 TRIM16 10626
Affinity Capture-MS Homo sapiens
120 TXLNA 200081
Two-hybrid Homo sapiens
121 NUMA1 4926
Affinity Capture-MS Homo sapiens
122 RGPD3  
Affinity Capture-MS Homo sapiens
123 HSPA5 3309
Affinity Capture-MS Homo sapiens
124 KRT3 3850
Two-hybrid Homo sapiens
125 DTNA  
Co-fractionation Homo sapiens
126 SNAPC5  
Two-hybrid Homo sapiens
127 CLIP1 6249
Affinity Capture-MS Homo sapiens
128 Zwint  
Affinity Capture-MS Mus musculus
129 Nup98  
Affinity Capture-MS Mus musculus
130 PXN 5829
Proximity Label-MS Homo sapiens
131 XPO1 7514
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
132 TPR 7175
Co-fractionation Homo sapiens
133 PELI2 57161
Two-hybrid Homo sapiens
134 C14orf119  
Two-hybrid Homo sapiens
135 CCDC186 55088
Affinity Capture-MS Homo sapiens
136 EEF2 1938
Co-fractionation Homo sapiens
137 ARFGEF1 10565
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
138 NUP88 4927
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
139 CUL3 8452
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
140 SPECC1 92521
Affinity Capture-MS Homo sapiens
141 NUP43 348995
Proximity Label-MS Homo sapiens
142 NUP214 8021
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
143 TRAF3 7187
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
144 SASS6 163786
Affinity Capture-MS Homo sapiens
145 TANK 10010
Affinity Capture-MS Homo sapiens
146 THAP1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
147 XPO6 23214
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
148 ARHGAP22 58504
Affinity Capture-MS Homo sapiens
149 CEP250 11190
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
150 COG6 57511
Affinity Capture-MS Homo sapiens
151 XPOT 11260
Co-fractionation Homo sapiens
152 Nup107  
Affinity Capture-MS Mus musculus
153 SSNA1 8636
Affinity Capture-MS Homo sapiens
154 NUTF2 10204
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
155 RGPD5  
Affinity Capture-MS Homo sapiens
156 COMMD6 170622
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
157 EI24  
Affinity Capture-MS Homo sapiens
158 DGCR6  
Two-hybrid Homo sapiens
159 TRIM33 51592
Affinity Capture-MS Homo sapiens
160 EIF5A 1984
Co-fractionation Homo sapiens
161 KIF18B 146909
Affinity Capture-MS Homo sapiens
162 COMMD2 51122
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
163 RANBP1 5902
Affinity Capture-MS Homo sapiens
164 USHBP1  
Two-hybrid Homo sapiens
165 CCDC88A 55704
Affinity Capture-MS Homo sapiens
166 ATF7IP2 80063
Two-hybrid Homo sapiens
167 ITSN1 6453
Cross-Linking-MS (XL-MS) Homo sapiens
168 RAE1 8480
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
169 ACBD5 91452
Proximity Label-MS Homo sapiens
170 COMMD1 150684
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
171 TACC3  
Affinity Capture-MS Homo sapiens
172 STAT4  
Proximity Label-MS Homo sapiens
173 CEP85L  
Affinity Capture-MS Homo sapiens
174 NUP54 53371
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
175 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
176 CLIC1 1192
Two-hybrid Homo sapiens
177 SIRT6  
Affinity Capture-MS Homo sapiens
178 NUP205 23165
Co-fractionation Homo sapiens
179 NXF1 10482
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
180 NUP133 55746
Co-fractionation Homo sapiens
181 HAUS1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
182 HSF4  
Two-hybrid Homo sapiens
183 MXD3  
Two-hybrid Homo sapiens
184 NXF2  
Reconstituted Complex Homo sapiens
185 CCHCR1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
186 RGPD8  
Affinity Capture-MS Homo sapiens
187 CCDC146  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
188 PIN1 5300
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
189 BFSP1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
190 ATXN7  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
191 CUL5 8065
Affinity Capture-MS Homo sapiens
192 PDHA1 5160
Affinity Capture-MS Homo sapiens
193 G3BP1 10146
Affinity Capture-MS Homo sapiens
194 SNAPIN 23557
Affinity Capture-MS Homo sapiens
195 G3BP2 9908
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
196 EIF4A3 9775
Co-fractionation Homo sapiens
197 NUP35 129401
Proximity Label-MS Homo sapiens
198 ADAM15 8751
Two-hybrid Homo sapiens
199 DDX19A 55308
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
200 NUP98 4928
Co-fractionation Homo sapiens
201 CCDC93 54520
Affinity Capture-MS Homo sapiens
202 BRK1 55845
Affinity Capture-MS Homo sapiens
203 TLE4  
Two-hybrid Homo sapiens
204 Nup214  
Affinity Capture-MS Mus musculus
Affinity Capture-MS Mus musculus
205 CCDC153  
Two-hybrid Homo sapiens
206 TXN 7295
Two-hybrid Homo sapiens
207 NUP107 57122
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
208 ABI2 10152
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
209 IK 3550
Two-hybrid Homo sapiens
210 PPP1R13B  
Affinity Capture-MS Homo sapiens
211 NCL 4691
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
212 KRT20 54474
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
213 ACOX1 51
Co-fractionation Homo sapiens
214 CCDC121  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
215 HEATR5A 25938
Co-fractionation Homo sapiens
216 CRCT1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
217 Ranbp2  
Affinity Capture-MS Mus musculus
218 SOX13  
Affinity Capture-MS Homo sapiens
219 HSPB11 51668
Two-hybrid Homo sapiens
220 KRAS 3845
Negative Genetic Homo sapiens
221 MYC  
Affinity Capture-MS Homo sapiens
222 PTRF 284119
Affinity Capture-MS Homo sapiens
223 GABPA 2551
Cross-Linking-MS (XL-MS) Homo sapiens
224 SSC5D 284297
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
225 FAM175B 23172
Affinity Capture-MS Homo sapiens
226 NIN 51199
Affinity Capture-MS Homo sapiens
227 RANBP2 5903
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
228 NUP188 23511
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which NUP62 is involved
PathwayEvidenceSource
Antiviral mechanism by IFN-stimulated genes TAS Reactome
Cell Cycle TAS Reactome
Cell Cycle IEA Reactome
Cell Cycle, Mitotic TAS Reactome
Cell Cycle, Mitotic IEA Reactome
Cellular response to heat stress TAS Reactome
Cellular responses to stimuli TAS Reactome
Cellular responses to stress TAS Reactome
Cytokine Signaling in Immune system TAS Reactome
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) TAS Reactome
Disease TAS Reactome
Disease IEA Reactome
Disorders of transmembrane transporters TAS Reactome
Export of Viral Ribonucleoproteins from Nucleus TAS Reactome
Gene expression (Transcription) TAS Reactome
Gene Silencing by RNA TAS Reactome
Glucose metabolism TAS Reactome
Glycolysis TAS Reactome
HCMV Early Events TAS Reactome
HCMV Infection TAS Reactome
HCMV Late Events TAS Reactome
HIV Infection IEA Reactome
HIV Infection TAS Reactome
HIV Life Cycle TAS Reactome
Host Interactions of HIV factors IEA Reactome
Host Interactions of HIV factors TAS Reactome
Immune System TAS Reactome
Infectious disease TAS Reactome
Infectious disease IEA Reactome
Influenza Infection TAS Reactome
Influenza Viral RNA Transcription and Replication TAS Reactome
Interactions of Rev with host cellular proteins IEA Reactome
Interactions of Rev with host cellular proteins TAS Reactome
Interactions of Vpr with host cellular proteins TAS Reactome
Interferon Signaling TAS Reactome
ISG15 antiviral mechanism TAS Reactome
Late Phase of HIV Life Cycle TAS Reactome
M Phase TAS Reactome
M Phase IEA Reactome
Metabolism TAS Reactome
Metabolism of carbohydrates TAS Reactome
Metabolism of non-coding RNA TAS Reactome
Metabolism of proteins TAS Reactome
Metabolism of proteins IEA Reactome
Metabolism of RNA TAS Reactome
Mitotic Anaphase IEA Reactome
Mitotic Metaphase and Anaphase IEA Reactome
Mitotic Prophase TAS Reactome
NEP/NS2 Interacts with the Cellular Export Machinery TAS Reactome
NS1 Mediated Effects on Host Pathways TAS Reactome
Nuclear Envelope (NE) Reassembly IEA Reactome
Nuclear Envelope Breakdown TAS Reactome
Nuclear import of Rev protein IEA Reactome
Nuclear Pore Complex (NPC) Disassembly TAS Reactome
Post-translational protein modification TAS Reactome
Post-translational protein modification IEA Reactome
Postmitotic nuclear pore complex (NPC) reformation IEA Reactome
Processing of Capped Intron-Containing Pre-mRNA TAS Reactome
Regulation of Glucokinase by Glucokinase Regulatory Protein TAS Reactome
Regulation of HSF1-mediated heat shock response TAS Reactome
Rev-mediated nuclear export of HIV RNA TAS Reactome
SARS-CoV Infections TAS Reactome
SARS-CoV-2 activates/modulates innate and adaptive immune responses TAS Reactome
SARS-CoV-2 Infection TAS Reactome
SARS-CoV-2-host interactions TAS Reactome
SLC transporter disorders TAS Reactome
snRNP Assembly TAS Reactome
SUMO E3 ligases SUMOylate target proteins TAS Reactome
SUMO E3 ligases SUMOylate target proteins IEA Reactome
SUMOylation TAS Reactome
SUMOylation IEA Reactome
SUMOylation of chromatin organization proteins TAS Reactome
SUMOylation of DNA damage response and repair proteins TAS Reactome
SUMOylation of DNA replication proteins IEA Reactome
SUMOylation of DNA replication proteins TAS Reactome
SUMOylation of RNA binding proteins TAS Reactome
SUMOylation of SUMOylation proteins TAS Reactome
SUMOylation of ubiquitinylation proteins TAS Reactome
Transcriptional regulation by small RNAs TAS Reactome
Transport of Mature mRNA derived from an Intron-Containing Transcript TAS Reactome
Transport of Mature mRNA Derived from an Intronless Transcript TAS Reactome
Transport of Mature mRNAs Derived from Intronless Transcripts TAS Reactome
Transport of Mature Transcript to Cytoplasm TAS Reactome
Transport of Ribonucleoproteins into the Host Nucleus TAS Reactome
Transport of the SLBP Dependant Mature mRNA TAS Reactome
Transport of the SLBP independent Mature mRNA TAS Reactome
tRNA processing TAS Reactome
tRNA processing in the nucleus TAS Reactome
Viral Infection Pathways TAS Reactome
Viral Infection Pathways IEA Reactome
Viral Messenger RNA Synthesis TAS Reactome
Vpr-mediated nuclear import of PICs TAS Reactome





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