Gene description for C9orf78
Gene name chromosome 9 open reading frame 78
Gene symbol C9orf78
Other names/aliases HCA59
HSPC220
bA409K20.3
Species Homo sapiens
 Database cross references - C9orf78
ExoCarta ExoCarta_51759
Entrez Gene 51759
HGNC 24932
UniProt Q9NZ63  
 C9orf78 identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for C9orf78
Subcellular Localization
    cytoplasm GO:0005737 IDA
    nucleoplasm GO:0005654 IDA
 Experiment description of studies that identified C9orf78 in exosomes
1
Experiment ID 237
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for C9orf78
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Supt5h  
Two-hybrid Mus musculus
View the network image/svg+xml
 Pathways in which C9orf78 is involved
No pathways found





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