Gene description for EPS15
Gene name	epidermal growth factor receptor pathway substrate 15
Gene symbol	EPS15
Other names/aliases	AF-1P AF1P MLLT5
Species	Homo sapiens
Database cross references - EPS15
ExoCarta	ExoCarta_2060
Entrez Gene	2060
HGNC	3419
MIM	600051
UniProt	P42566
EPS15 identified in exosomes derived from the following tissue/cell type
Platelets	25332113
Platelets	25332113
Platelets	25332113
Thymus	23844026

Gene ontology annotations for EPS15

Molecular Function     polyubiquitin binding GO:0031593 IDA     calcium ion binding GO:0005509 IEA     SH3 domain binding GO:0017124 IEA     protein binding GO:0005515 IPI     identical protein binding GO:0042802 IEA Biological Process     vesicle organization GO:0016050 TAS     clathrin coat assembly GO:0048268 IDA     receptor-mediated endocytosis of virus by host cell GO:0019065 IMP     cell proliferation GO:0008283 TAS     viral entry into host cell GO:0046718 IMP     endocytic recycling GO:0032456 IC     Golgi to endosome transport GO:0006895 IMP     epidermal growth factor receptor signaling pathway GO:0007173 TAS     protein transport GO:0015031 IEA     negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 TAS Subcellular Localization     plasma membrane GO:0005886 IDA     cytosol GO:0005829 TAS     ciliary membrane GO:0060170 IEA     aggresome GO:0016235 IDA     coated pit GO:0005905 TAS     AP-2 adaptor complex GO:0030122 IEA     intracellular membrane-bounded organelle GO:0043231 IDA     cytoplasm GO:0005737 IDA     early endosome membrane GO:0031901 IEA     membrane GO:0016020 IDA