Gene description for Myh10
Gene name myosin, heavy polypeptide 10, non-muscle
Gene symbol Myh10
Other names/aliases 5730504C04Rik
9330167F11Rik
Fltn
Myhn-2
Myhn2
NMHC II-B
NMHC-B
NMHCII-B
NMMHC II-b
NMMHC-B
NMMHC-IIB
SMemb
mKIAA3005
Species Mus musculus
 Database cross references - Myh10
ExoCarta ExoCarta_77579
Entrez Gene 77579
UniProt Q61879  
 Myh10 identified in exosomes derived from the following tissue/cell type
Pancreatic cells 19351151    
 Gene ontology annotations for Myh10
Molecular Function
    actin-dependent ATPase activity GO:0030898 ISO
    actin filament binding GO:0051015 ISO
    actin binding GO:0003779 IEA
    nucleotide binding GO:0000166 IEA
    ADP binding GO:0043531 ISO
    microfilament motor activity GO:0000146 ISO
    calmodulin binding GO:0005516 IEA
    motor activity GO:0003774 IEA
    protein binding GO:0005515 IPI
    ATP binding GO:0005524 ISO
Biological Process
    metabolic process GO:0008152 ISO
    mitotic cytokinesis GO:0000281 ISO
    axon guidance GO:0007411 IMP
    nuclear migration GO:0007097 IMP
    myofibril assembly GO:0030239 IMP
    neuron migration GO:0001764 IMP
    exocytosis GO:0006887 IMP
    neuron projection development GO:0031175 IMP
    in utero embryonic development GO:0001701 IMP
    actomyosin structure organization GO:0031032 ISO
    axonogenesis GO:0007409 IMP
    fourth ventricle development GO:0021592 IMP
    cell adhesion GO:0007155 IEA
    brain development GO:0007420 IMP
    neuromuscular process controlling balance GO:0050885 IMP
    actin filament-based movement GO:0030048 ISO
    cerebellar Purkinje cell layer development GO:0021680 IMP
    regulation of cell shape GO:0008360 IMP
    third ventricle development GO:0021678 IMP
    adult heart development GO:0007512 IMP
    retina development in camera-type eye GO:0060041 IMP
    plasma membrane repair GO:0001778 IMP
    lateral ventricle development GO:0021670 IMP
    actin cytoskeleton organization GO:0030036 IGI
    substrate-dependent cell migration, cell extension GO:0006930 IMP
    cardiac myofibril assembly GO:0055003 IMP
    ventricular cardiac muscle cell development GO:0055015 IMP
    cell proliferation GO:0008283 IMP
Subcellular Localization
    plasma membrane GO:0005886 IDA
    nucleus GO:0005634 ISO
    actin cytoskeleton GO:0015629 ISO
    dendritic spine GO:0043197 IDA
    neuron projection GO:0043005 IDA
    myosin II filament GO:0097513 ISO
    neuromuscular junction GO:0031594 IDA
    cleavage furrow GO:0032154 ISO
    cell cortex GO:0005938 ISO
    extracellular exosome GO:0070062 ISO
    myosin II complex GO:0016460 ISO
    cell projection GO:0042995 IEA
    axon GO:0030424 IDA
    actomyosin GO:0042641 ISO
    growth cone GO:0030426 IDA
    brush border GO:0005903 IDA
    neuronal cell body GO:0043025 IDA
    spindle GO:0005819 IDA
    cytoplasm GO:0005737 ISO
    mitochondrion GO:0005739 ISO
    stress fiber GO:0001725 ISO
    midbody GO:0030496 ISO
    myosin complex GO:0016459 IDA
 Experiment description of studies that identified Myh10 in exosomes
1
Experiment ID 188
ISEV standards
EM
EV Biophysical techniques
GAPDH|UCHL1|HSP90
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors Lee HS, Jeong J, Lee KJ.
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Myh10
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 PBX1  
Two-hybrid Homo sapiens
View the network image/svg+xml



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