Gene description for MYO5C
Gene name myosin VC
Gene symbol MYO5C
Other names/aliases -
Species Homo sapiens
 Database cross references - MYO5C
ExoCarta ExoCarta_55930
Entrez Gene 55930
HGNC 7604
MIM 610022
UniProt Q9NQX4  
 MYO5C identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for MYO5C
Molecular Function
    calmodulin binding GO:0005516 IEA
    ATP binding GO:0005524 IEA
    motor activity GO:0003774 IEA
    actin binding GO:0003779 IEA
Biological Process
    metabolic process GO:0008152 IEA
Subcellular Localization
    myosin complex GO:0016459 IEA
    extracellular exosome GO:0070062 IDA
 Experiment description of studies that identified MYO5C in exosomes
1
Experiment ID 237
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for MYO5C
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which MYO5C is involved
No pathways found





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