Experiment description of studies that identified MYO5C in exosomes

1 Experiment ID 237 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N" Journal name Carcinogenesis Publication year 2015 Sample Hepatocytes Sample name MIHA Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RNA Sequencing

Protein-protein interactions for MYO5C

Protein Interactor ExoCarta ID Identification method PubMed Species 1 ABCG2 9429 Affinity Capture-MS Homo sapiens 2 ACTR2 10097 Affinity Capture-MS Homo sapiens 3 ARHGAP21 57584 Affinity Capture-MS Homo sapiens 4 HECTD1 25831 Affinity Capture-MS Homo sapiens 5 ISG15 9636 Affinity Capture-MS Homo sapiens 6 SPECC1L 23384 Affinity Capture-MS Homo sapiens 7 GMNN   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 8 ACRBP   Affinity Capture-MS Homo sapiens 9 Tpm1 22003 Affinity Capture-MS Mus musculus 10 EEF1G 1937 Cross-Linking-MS (XL-MS) Homo sapiens 11 POT1   Two-hybrid Homo sapiens 12 TMEM161A   Affinity Capture-MS Homo sapiens 13 ARPC2 10109 Affinity Capture-MS Homo sapiens 14 TPM2 7169 Affinity Capture-MS Homo sapiens 15 MOAP1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 16 P4HA2 8974 Affinity Capture-MS Homo sapiens 17 CRYL1 51084 Affinity Capture-MS Homo sapiens 18 Calml3   Affinity Capture-MS Mus musculus 19 ACTC1 70 Cross-Linking-MS (XL-MS) Homo sapiens 20 DBN1 1627 Affinity Capture-MS Homo sapiens 21 RBX1 9978 Affinity Capture-MS Homo sapiens 22 Actb 11461 Affinity Capture-MS Mus musculus 23 CLTB 1212 Affinity Capture-MS Homo sapiens 24 BRWD1   Affinity Capture-MS Homo sapiens 25 CLIC5 53405 Affinity Capture-MS Homo sapiens 26 CAPZB 832 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 27 PPP1R12A 4659 Affinity Capture-MS Homo sapiens 28 CDC16 8881 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 29 CORO1B 57175 Affinity Capture-MS Homo sapiens 30 PPP1CB 5500 Affinity Capture-MS Homo sapiens 31 KIF23 9493 Affinity Capture-MS Homo sapiens 32 ACTR3 10096 Affinity Capture-MS Homo sapiens 33 AP2A1 160 Affinity Capture-MS Homo sapiens 34 CALD1 800 Affinity Capture-MS Homo sapiens 35 RAB3B 5865 Proximity Label-MS Homo sapiens 36 IMPDH2 3615 Proximity Label-MS Homo sapiens 37 KRT40   Affinity Capture-MS Homo sapiens 38 IQGAP1 8826 Affinity Capture-MS Homo sapiens 39 CALM3 808 Affinity Capture-MS Homo sapiens 40 TULP2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 41 CEP162   Affinity Capture-MS Homo sapiens 42 SPDEF   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 43 MYO1B 4430 Affinity Capture-MS Homo sapiens 44 TMOD1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 45 TPRN 286262 Affinity Capture-MS Homo sapiens 46 ARPC5L 81873 Affinity Capture-MS Homo sapiens 47 SH3BGRL 6451 Affinity Capture-MS Homo sapiens 48 Lima1   Affinity Capture-MS Mus musculus 49 KIF14 9928 Affinity Capture-MS Homo sapiens 50 CCDC114   Affinity Capture-MS Homo sapiens 51 NAP1L2   Affinity Capture-MS Homo sapiens 52 PFN1 5216 Proximity Label-MS Homo sapiens 53 PPP1CA 5499 Affinity Capture-MS Homo sapiens 54 MYO18A 399687 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 55 CAPZA1 829 Co-fractionation Homo sapiens Affinity Capture-MS Homo sapiens 56 LUZP1 7798 Affinity Capture-MS Homo sapiens 57 PPP6R2 9701 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 58 RAI14 26064 Affinity Capture-MS Homo sapiens 59 EIF2B5 8893 Affinity Capture-MS Homo sapiens 60 POC1A   Affinity Capture-MS Homo sapiens 61 LRRFIP2 9209 Affinity Capture-MS Homo sapiens 62 DTNBP1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 63 PTP4A3   Affinity Capture-MS Homo sapiens 64 CDH5   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 65 MYH9 4627 Affinity Capture-MS Homo sapiens 66 ACTN4 81 Affinity Capture-MS Homo sapiens 67 JADE2 23338 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 68 ARHGAP11A   Affinity Capture-MS Homo sapiens 69 PNMA2   Affinity Capture-MS Homo sapiens 70 PEX14 5195 Proximity Label-MS Homo sapiens 71 CREB3   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 72 KRT2 3849 Affinity Capture-MS Homo sapiens 73 Coro1c 23790 Affinity Capture-MS Mus musculus 74 ARPC5 10092 Affinity Capture-MS Homo sapiens 75 ACTG1 71 Affinity Capture-MS Homo sapiens 76 PIPSL 266971 Affinity Capture-MS Homo sapiens 77 FLII 2314 Affinity Capture-MS Homo sapiens 78 TUBA3C 7278 Affinity Capture-MS Homo sapiens 79 ANLN 54443 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 80 ACTL8   Affinity Capture-MS Homo sapiens 81 DKK3 27122 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 82 LIMA1 51474 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 83 WHAMMP3   Affinity Capture-MS Homo sapiens 84 Myh9 17886 Affinity Capture-MS Mus musculus 85 TMOD4   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 86 ARPC1B 10095 Affinity Capture-MS Homo sapiens 87 ECT2 1894 Affinity Capture-MS Homo sapiens 88 DQX1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 89 ERLEC1 27248 Affinity Capture-MS Homo sapiens 90 CTTN 2017 Affinity Capture-MS Homo sapiens 91 SPECC1 92521 Affinity Capture-MS Homo sapiens 92 MYO5A 4644 Affinity Capture-MS Homo sapiens 93 MYO19   Affinity Capture-MS Homo sapiens 94 SIN3B   Affinity Capture-MS Homo sapiens 95 SPTBN1 6711 Affinity Capture-MS Homo sapiens 96 SAAL1 113174 Affinity Capture-MS Homo sapiens 97 DCAF6 55827 Affinity Capture-MS Homo sapiens 98 SYNPO 11346 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 99 FOS 2353 Proximity Label-MS Homo sapiens 100 Flnb 286940 Affinity Capture-MS Mus musculus 101 MYC   Affinity Capture-MS Homo sapiens 102 CLIC1 1192 Affinity Capture-MS Homo sapiens 103 ATP5S 27109 Affinity Capture-MS Homo sapiens 104 TMOD3 29766 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 105 MPZL1 9019 Affinity Capture-MS Homo sapiens 106 N4BP3   Affinity Capture-MS Homo sapiens 107 NDC80 10403 Proximity Label-MS Homo sapiens 108 CGN   Affinity Capture-MS Homo sapiens 109 DPM2 8818 Affinity Capture-MS Homo sapiens 110 AKAP2 11217 Affinity Capture-MS Homo sapiens 111 CD109 135228 Affinity Capture-MS Homo sapiens 112 KRT19 3880 Proximity Label-MS Homo sapiens 113 CCDC8   Affinity Capture-MS Homo sapiens 114 ACBD5 91452 Proximity Label-MS Homo sapiens Affinity Capture-MS Homo sapiens 115 TPM3 7170 Affinity Capture-MS Homo sapiens 116 FTL 2512 Affinity Capture-MS Homo sapiens 117 KRT18 3875 Proximity Label-MS Homo sapiens 118 ARPC3 10094 Affinity Capture-MS Homo sapiens 119 PDLIM7 9260 Affinity Capture-MS Homo sapiens 120 NEXN 91624 Affinity Capture-MS Homo sapiens 121 PLEKHA4 57664 Affinity Capture-MS Homo sapiens 122 SPTAN1 6709 Affinity Capture-MS Homo sapiens 123 Tmod3 50875 Affinity Capture-MS Mus musculus 124 SVIL 6840 Affinity Capture-MS Homo sapiens 125 AVIL   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 126 TP53 7157 Affinity Capture-MS Homo sapiens 127 PGK1 5230 Affinity Capture-MS Homo sapiens 128 HSPA8 3312 Affinity Capture-MS Homo sapiens 129 PEX19 5824 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 130 TRIM52   Affinity Capture-MS Homo sapiens 131 CXCL6   Affinity Capture-MS Homo sapiens 132 MISP 126353 Affinity Capture-MS Homo sapiens 133 EZR 7430 Proximity Label-MS Homo sapiens 134 SCP2 6342 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 135 Myo1c 17913 Affinity Capture-MS Mus musculus 136 IKBKG 8517 Two-hybrid Homo sapiens 137 CAPZA2 830 Co-fractionation Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 138 SEPT10 151011 Proximity Label-MS Homo sapiens 139 DCTN2 10540 Proximity Label-MS Homo sapiens 140 ELAVL1 1994 Affinity Capture-RNA Homo sapiens 141 LSS 4047 Affinity Capture-MS Homo sapiens 142 DDX58 23586 Affinity Capture-RNA Homo sapiens 143 Myh10 77579 Affinity Capture-MS Mus musculus 144 ANAPC2 29882 Proximity Label-MS Homo sapiens 145 RAB8A 4218 Two-hybrid Homo sapiens 146 AFAP1 60312 Affinity Capture-MS Homo sapiens 147 TMEM257   Affinity Capture-MS Homo sapiens 148 KRT38 8687 Affinity Capture-MS Homo sapiens 149 INF2 64423 Affinity Capture-MS Homo sapiens 150 DAPK3 1613 Affinity Capture-MS Homo sapiens 151 FLNA 2316 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 152 RAB11A 8766 Proximity Label-MS Homo sapiens 153 MYO1E 4643 Affinity Capture-MS Homo sapiens 154 GAGE5   Affinity Capture-MS Homo sapiens 155 MYO6 4646 Affinity Capture-MS Homo sapiens 156 AR 367 Affinity Capture-MS Homo sapiens 157 LURAP1   Affinity Capture-MS Homo sapiens 158 DSG2 1829 Affinity Capture-MS Homo sapiens 159 HSPA2 3306 Affinity Capture-MS Homo sapiens View the network

Pathways in which MYO5C is involved

No pathways found