Gene description for CRYL1
Gene name crystallin, lambda 1
Gene symbol CRYL1
Other names/aliases GDH
HEL30
lambda-CRY
Species Homo sapiens
 Database cross references - CRYL1
ExoCarta ExoCarta_51084
Entrez Gene 51084
HGNC 18246
MIM 609877
UniProt Q9Y2S2  
 CRYL1 identified in exosomes derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for CRYL1
Molecular Function
    3-hydroxyacyl-CoA dehydrogenase activity GO:0003857 IEA
    NAD+ binding GO:0070403 IDA
    L-gulonate 3-dehydrogenase activity GO:0050104 IDA
    protein homodimerization activity GO:0042803 IPI
Biological Process
    oxidation-reduction process GO:0055114 IEA
    fatty acid metabolic process GO:0006631 IEA
Subcellular Localization
    extracellular exosome GO:0070062 IDA
    nucleus GO:0005634 IDA
    cytoplasm GO:0005737 IDA
    nucleolus GO:0005730 IDA
    cytosol GO:0005829 ISS
    Golgi apparatus GO:0005794 IDA
    plasma membrane GO:0005886 IDA
 Experiment description of studies that identified CRYL1 in exosomes
1
Experiment ID 63
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
AQP2
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for CRYL1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which CRYL1 is involved
No pathways found





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