Gene description for BRCA2
Gene name	breast cancer 2, early onset
Gene symbol	BRCA2
Other names/aliases	BRCC2 BROVCA2 FACD FAD FAD1 FANCD FANCD1 GLM3 PNCA2 XRCC11
Species	Homo sapiens
Database cross references - BRCA2
ExoCarta	ExoCarta_675
Vesiclepedia	VP_675
Entrez Gene	675
HGNC	1101
MIM	600185
UniProt	P51587
BRCA2 identified in exosomes derived from the following tissue/cell type
Neuroblastoma cells	25944692

Gene ontology annotations for BRCA2

Molecular Function     single-stranded DNA binding GO:0003697 IDA     H3 histone acetyltransferase activity GO:0010484 IDA     protease binding GO:0002020 IPI     protein binding GO:0005515 IPI     H4 histone acetyltransferase activity GO:0010485 IDA     histone acetyltransferase activity GO:0004402 IDA     gamma-tubulin binding GO:0043015 IPI Biological Process     spermatogenesis GO:0007283 IEA     DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator GO:0006978 IEA     chromosome organization GO:0051276 IBA     brain development GO:0007420 IEA     hemopoiesis GO:0030097 IEA     cell aging GO:0007569 IEA     response to gamma radiation GO:0010332 IEA     female gonad development GO:0008585 IEA     histone H4 acetylation GO:0043967 IDA     oocyte maturation GO:0001556 IEA     regulation of cytokinesis GO:0032465 IEA     nucleotide-excision repair GO:0006289 IMP     response to UV-C GO:0010225 IEA     replication fork protection GO:0048478 IEA     inner cell mass cell proliferation GO:0001833 IEA     DNA repair GO:0006281 TAS     double-strand break repair via homologous recombination GO:0000724 TAS     double-strand break repair GO:0006302 TAS     positive regulation of transcription, DNA-templated GO:0045893 IDA     centrosome duplication GO:0051298 IMP     negative regulation of mammary gland epithelial cell proliferation GO:0033600 IDA     cytokinesis GO:0000910 IDA     positive regulation of mitotic cell cycle GO:0045931 IEA     intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator GO:0042771 IEA     response to X-ray GO:0010165 IEA     male meiosis I GO:0007141 IEA     histone H3 acetylation GO:0043966 IDA Subcellular Localization     secretory granule GO:0030141 IDA     centrosome GO:0005813 IDA     BRCA2-MAGE-D1 complex GO:0033593 IDA     nucleus GO:0005634 IDA     nucleoplasm GO:0005654 TAS     cytoplasm GO:0005737 IDA     protein complex GO:0043234 IDA