Experiment description of studies that identified IER2 in exosomes

1 Experiment ID 235 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N" Journal name Carcinogenesis Publication year 2015 Sample Hepatocellular carcinoma cells Sample name HKCI-8 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RT-PCR RNA Sequencing

2 Experiment ID 237 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N" Journal name Carcinogenesis Publication year 2015 Sample Hepatocytes Sample name MIHA Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RNA Sequencing

Protein-protein interactions for IER2

Protein Interactor ExoCarta ID Identification method PubMed Species 1 HNRNPH1 3187 Affinity Capture-RNA Homo sapiens 2 CDCA2 157313 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 3 RNF40 9810 Affinity Capture-MS Homo sapiens 4 UTRN 7402 Affinity Capture-MS Homo sapiens 5 KPNA3 3839 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 6 PPP2R2B 5521 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 7 PITX2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 8 SGOL2 151246 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 9 HSPA8 3312 Affinity Capture-MS Homo sapiens 10 RGPD8   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 11 GLE1 2733 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 12 NME2 4831 Affinity Capture-MS Homo sapiens 13 ATG12   Two-hybrid Homo sapiens 14 ZBTB40   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 15 TRIM27   Affinity Capture-MS Homo sapiens 16 KDM5C   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 17 ELAVL1 1994 Affinity Capture-RNA Homo sapiens 18 PPP2R2C 5522 Affinity Capture-MS Homo sapiens 19 ZC3H11A   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 20 KPNA4 3840 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 21 HDGFRP2 84717 Affinity Capture-MS Homo sapiens 22 BRCA2 675 Affinity Capture-MS Homo sapiens 23 PPP2R1B 5519 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 24 PPP2CB 5516 Affinity Capture-MS Homo sapiens 25 PPP2R1A 5518 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 26 GALC 2581 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 27 NUP153 9972 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 28 PPP2CA 5515 Affinity Capture-MS Homo sapiens 29 NSMCE4A   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 30 HSF2BP   Two-hybrid Homo sapiens 31 PPP2R2A 5520 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 32 MCM3AP   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 33 PPP2R2D 55844 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 34 TP73   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 35 MDM2   Affinity Capture-MS Homo sapiens 36 RANBP2 5903 Affinity Capture-MS Homo sapiens View the network

Pathways in which IER2 is involved

No pathways found