Gene description for CDCA2
Gene name cell division cycle associated 2
Gene symbol CDCA2
Other names/aliases PPP1R81
Repo-Man
Species Homo sapiens
 Database cross references - CDCA2
ExoCarta ExoCarta_157313
Entrez Gene 157313
HGNC 14623
UniProt Q69YH5  
 CDCA2 identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for CDCA2
Biological Process
    mitotic nuclear division GO:0007067 IEA
    positive regulation of protein dephosphorylation GO:0035307 IMP
    chromosome segregation GO:0007059 IEA
    cell division GO:0051301 IEA
Subcellular Localization
    cytoplasm GO:0005737 IDA
    chromosome GO:0005694 IDA
    nucleoplasm GO:0005654 IDA
 Experiment description of studies that identified CDCA2 in exosomes
1
Experiment ID 237
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for CDCA2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which CDCA2 is involved
No pathways found





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