Gene description for HIST1H4A
Gene name histone cluster 1, H4a
Gene symbol HIST1H4A
Other names/aliases H4FA
Species Homo sapiens
 Database cross references - HIST1H4A
ExoCarta ExoCarta_8359
Vesiclepedia VP_8359
Entrez Gene 8359
HGNC 4781
MIM 602822
UniProt P62805  
 HIST1H4A identified in sEVs derived from the following tissue/cell type
Bladder cancer cells 20224111    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 17956143    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Colorectal cancer cells 34887515    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 36706192    
Embryonic kidney cells 36706192    
Endothelial cells 26027894    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Hepatocellular carcinoma cells 26054723    
Hepatocellular carcinoma cells 26054723    
Hepatocytes 26054723    
Keratinocytes 19530224    
Keratinocytes 19530224    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Mesenchymal stem cells Unpublished / Not applicable
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Neuroblastoma cells 25944692    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
Saliva 19199708    
Squamous carcinoma cells 20124223    
T lymphocytes 34108659    
Thymus 23844026    
Urine 22418980    
Urine 22418980    
 Gene ontology annotations for HIST1H4A
Molecular Function
    DNA binding GO:0003677 IBA
    DNA binding GO:0003677 TAS
    RNA binding GO:0003723 HDA
    protein binding GO:0005515 IPI
    structural constituent of chromatin GO:0030527 IDA
    protein heterodimerization activity GO:0046982 IEA
Biological Process
    chromatin organization GO:0006325 NAS
    nucleosome assembly GO:0006334 IBA
    nucleosome assembly GO:0006334 IDA
    telomere organization GO:0032200 TAS
    negative regulation of megakaryocyte differentiation GO:0045653 IDA
    protein localization to CENP-A containing chromatin GO:0061644 NAS
Subcellular Localization
    chromosome, telomeric region GO:0000781 HDA
    nucleosome GO:0000786 IDA
    nucleosome GO:0000786 IPI
    nucleosome GO:0000786 TAS
    extracellular region GO:0005576 TAS
    nucleus GO:0005634 HDA
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 TAS
    membrane GO:0016020 HDA
    protein-containing complex GO:0032991 IDA
    CENP-A containing nucleosome GO:0043505 IPI
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified HIST1H4A in sEVs
1
Experiment ID 76
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|GAPDH|HSP90|CD81|CD9|CD63|LAMP1|MHCI
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20224111    
Organism Homo sapiens
Experiment description Proteomics analysis of bladder cancer exosomes.
Authors "Welton JL, Khanna S, Giles PJ, Brennan P, Brewis IA, Staffurth J, Mason MD, Clayton A."
Journal name MCP
Publication year 2010
Sample Bladder cancer cells
Sample name HT1376
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.10-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF/TOF]
Western blotting
FACS
2
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
3
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
4
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
5
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
6
Experiment ID 494
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD151|CD63|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Osteoarthritic cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
7
Experiment ID 496
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Healthy cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
8
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
9
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
10
Experiment ID 20
MISEV standards
✔
EM
Biophysical techniques
✔
HSP90|CD63|CD81|LAMP1
Enriched markers
✔
GOLGA2|cytochrome c
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17956143    
Organism Homo sapiens
Experiment description Proteomic analysis of microvesicles derived from human colorectal cancer cells.
Authors "Choi DS, Lee JM, Park GW, Lim HW, Bang JY, Kim YK, Kwon KH, Kwon HJ, Kim KP, Gho YS"
Journal name JPR
Publication year 2007
Sample Colorectal cancer cells
Sample name HT29
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Diafiltration
Flotation density 1.16 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
11
Experiment ID 207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
12
Experiment ID 208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 282
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Ultracentrifugation - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
15
Experiment ID 283
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Ultracentrifugation - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
16
Experiment ID 285
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Sequential centrifugal ultrafiltration - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Sequential centrifugal ultrafiltration
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
17
Experiment ID 286
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Sequential centrifugal ultrafiltration - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Sequential centrifugal ultrafiltration
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
18
Experiment ID 1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
19
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
20
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
21
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
22
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
23
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
24
Experiment ID 1275
MISEV standards
Biophysical techniques
✔
CD9|TSG101|FLOT1|FLOT2|RAB35|RAB5A|GAPDH|TFRC|CD63|Alix
Enriched markers
✔
PCNA|CANX|GAPDH|HSP90AA1|HSP90B1
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
25
Experiment ID 1280
MISEV standards
Biophysical techniques
✔
TSG101|CD9|FLOT1|FLOT2|RAB35|RAB5A|GAPDH|TFRC|CD63|Alix
Enriched markers
✔
PCNA|CANX|GAPDH|HSP90AA1|HSP90B1
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T - Fraction 5
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density 1.151 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
26
Experiment ID 226
MISEV standards
✔
EM
Biophysical techniques
✔
GAPDH|CD9|FLOT1
Enriched markers
✔
LMNA|H2AFX|ATP5A1|TOMM20
Negative markers
✘ Particle analysis
Identified molecule mRNA
Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
PubMed ID 26027894    
Organism Homo sapiens
Experiment description "Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting"
Authors "Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar"
Journal name Journal of Extracellular Vesicles
Publication year 2015
Sample Endothelial cells
Sample name HMEC-1
Isolation/purification methods Differential ultracentrifugation
Sucrose density gradient
Flotation density 1.10 g/mL
Molecules identified in the study miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA
Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting
27
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
28
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
29
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
30
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
31
Experiment ID 234
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-C3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
32
Experiment ID 235
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
33
Experiment ID 237
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
34
Experiment ID 237
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
35
Experiment ID 189
MISEV standards
✔
EM
Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19530224    
Organism Homo sapiens
Experiment description Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes.
Authors "Chavez-Muñoz C, Kilani RT, Ghahary A."
Journal name J Cell Physiol
Publication year 2009
Sample Keratinocytes
Sample name Keratinocytes - Differentiated
Isolation/purification methods Differential centrifugation
Filtration
Sucrose cushion
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
36
Experiment ID 190
MISEV standards
✔
EM
Biophysical techniques
✔
HSC70
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19530224    
Organism Homo sapiens
Experiment description Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes.
Authors "Chavez-Muñoz C, Kilani RT, Ghahary A."
Journal name J Cell Physiol
Publication year 2009
Sample Keratinocytes
Sample name Keratinocytes - Undifferentiated
Isolation/purification methods Differential centrifugation
Filtration
Sucrose cushion
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
37
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
38
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
39
Experiment ID 254
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name MNT-1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
40
Experiment ID 255
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name G1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
41
Experiment ID 256
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 501mel
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
42
Experiment ID 257
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name Daju
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
43
Experiment ID 258
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name SKMEL28
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
44
Experiment ID 259
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name A375M
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
45
Experiment ID 260
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 1205Lu
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
46
Experiment ID 126
MISEV standards
✘ Biophysical techniques
✔
GAPDH
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
47
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
48
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
49
Experiment ID 224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
50
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
51
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
52
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
53
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
54
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
55
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
56
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
57
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
58
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
59
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
60
Experiment ID 138
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|LAMP2|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name DU145 - Rep 2
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
61
Experiment ID 139
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|LAMP2|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name DU145 - Rep 3
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
62
Experiment ID 140
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|LAMP2|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name VCaP - Rep 2
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
63
Experiment ID 141
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|LAMP2|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name VCaP - Rep 3
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
64
Experiment ID 142
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|LAMP2|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name LNCaP - Rep 2
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
65
Experiment ID 143
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|LAMP2|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name LNCaP - Rep 3
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
66
Experiment ID 144
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name C4-2 - Rep 2
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
67
Experiment ID 145
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|CD10
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name C4-2 - Rep 3
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
68
Experiment ID 146
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name RWPE - Rep 2
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
69
Experiment ID 834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
70
Experiment ID 835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
71
Experiment ID 66
MISEV standards
✔
IEM
Biophysical techniques
✔
TSG101|Alix|CD63|CD81
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19199708    
Organism Homo sapiens
Experiment description Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Authors "Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR"
Journal name JPR
Publication year 2009
Sample Saliva
Sample name Saliva
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy
72
Experiment ID 191
MISEV standards
✘ Biophysical techniques
✔
Alix|CD81|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
73
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
74
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
75
Experiment ID 196
MISEV standards
✔
EM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors "Raj DA, Fiume I, Capasso G, Pocsfalvi G."
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal high density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
76
Experiment ID 197
MISEV standards
✔
EM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors "Raj DA, Fiume I, Capasso G, Pocsfalvi G."
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal low density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for HIST1H4A
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ZSCAN29  
Affinity Capture-MS Homo sapiens
2 MED17  
Affinity Capture-MS Homo sapiens
3 AATF  
Affinity Capture-MS Homo sapiens
4 HIST1H4A 8359
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
5 TOP2B 7155
Affinity Capture-MS Homo sapiens
6 FA2H  
Affinity Capture-MS Homo sapiens
7 MED29  
Affinity Capture-MS Homo sapiens
8 TUBB8 347688
Affinity Capture-MS Homo sapiens
9 UBC 7316
Cross-Linking-MS (XL-MS) Homo sapiens
10 THOC7 80145
Affinity Capture-MS Homo sapiens
11 VHL  
Affinity Capture-MS Homo sapiens
12 INTS1 26173
Affinity Capture-MS Homo sapiens
13 TAF1  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
FRET Homo sapiens
Protein-peptide Homo sapiens
14 RNF208  
Affinity Capture-MS Homo sapiens
15 ELF4 2000
Affinity Capture-MS Homo sapiens
16 PTRH2 51651
Affinity Capture-MS Homo sapiens
17 WDR76  
Affinity Capture-MS Homo sapiens
18 MEAF6  
Affinity Capture-MS Homo sapiens
19 GFPT1 2673
Co-fractionation Homo sapiens
20 CTDSPL2  
Affinity Capture-MS Homo sapiens
21 JRKL  
Affinity Capture-MS Homo sapiens
22 BRCC3 79184
Affinity Capture-MS Homo sapiens
23 ATAD5  
Affinity Capture-MS Homo sapiens
24 FAF1 11124
Co-fractionation Homo sapiens
25 UCHL5 51377
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
26 VCY  
Cross-Linking-MS (XL-MS) Homo sapiens
27 MECP2 4204
Affinity Capture-MS Homo sapiens
28 WBP2 23558
Reconstituted Complex Homo sapiens
29 KIF14 9928
Affinity Capture-MS Homo sapiens
30 RBMX 27316
Affinity Capture-MS Homo sapiens
31 AURKA 6790
Affinity Capture-MS Homo sapiens
32 RCC2 55920
Affinity Capture-MS Homo sapiens
33 TCOF1 6949
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
34 SPTA1  
Affinity Capture-MS Homo sapiens
35 JADE3  
Affinity Capture-MS Homo sapiens
36 WDR89  
Affinity Capture-MS Homo sapiens
37 RRP9 9136
Affinity Capture-MS Homo sapiens
38 CSTF2 1478
Affinity Capture-MS Homo sapiens
39 BRE 9577
Affinity Capture-MS Homo sapiens
40 FANCM 57697
Affinity Capture-MS Homo sapiens
41 PPIH 10465
Affinity Capture-MS Homo sapiens
42 EEF1E1 9521
Affinity Capture-MS Homo sapiens
43 FOXL2  
Affinity Capture-MS Homo sapiens
44 YAP1 10413
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
45 IWS1  
Affinity Capture-MS Homo sapiens
46 NAA10 8260
Biochemical Activity Homo sapiens
47 SYNCRIP 10492
Affinity Capture-MS Homo sapiens
48 RFC4 5984
Affinity Capture-MS Homo sapiens
49 CUL2 8453
Affinity Capture-MS Homo sapiens
50 RRP1B 23076
Affinity Capture-MS Homo sapiens
51 MAX  
Affinity Capture-MS Homo sapiens
52 SEC61B 10952
Affinity Capture-MS Homo sapiens
53 SLC25A5 292
Affinity Capture-MS Homo sapiens
54 CD3EAP  
Affinity Capture-MS Homo sapiens
55 ANLN 54443
Affinity Capture-MS Homo sapiens
56 ONECUT2  
Affinity Capture-MS Homo sapiens
57 HIST1H2AD 3013
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-MS Homo sapiens
58 HSPA5 3309
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
59 RBM39 9584
Affinity Capture-MS Homo sapiens
60 ASXL2  
Affinity Capture-MS Homo sapiens
61 HOXA10  
Affinity Capture-MS Homo sapiens
62 HADHA 3030
Affinity Capture-MS Homo sapiens
63 NASP 4678
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
64 MUS81  
Affinity Capture-MS Homo sapiens
65 AHCYL1 10768
Co-fractionation Homo sapiens
66 LRRC59 55379
Affinity Capture-MS Homo sapiens
67 LMNB1 4001
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
68 SIRT7  
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
69 SRSF4 6429
Affinity Capture-MS Homo sapiens
70 LMO7 4008
Affinity Capture-MS Homo sapiens
71 NPM3 10360
Affinity Capture-MS Homo sapiens
72 BCAP31 10134
Cross-Linking-MS (XL-MS) Homo sapiens
73 RSL24D1  
Affinity Capture-MS Homo sapiens
74 EPRS 2058
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-MS Homo sapiens
75 ZC3H11A  
Affinity Capture-MS Homo sapiens
76 SIN3B  
Affinity Capture-MS Homo sapiens
77 NIP7 51388
Affinity Capture-MS Homo sapiens
78 NTHL1  
Affinity Capture-MS Homo sapiens
79 HIST1H1B 3009
Affinity Capture-MS Homo sapiens
80 TMEM237 65062
Affinity Capture-MS Homo sapiens
81 ZMYND8 23613
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
82 SPATA5 166378
Affinity Capture-MS Homo sapiens
83 RFWD3  
Affinity Capture-MS Homo sapiens
84 CETN2 1069
Affinity Capture-MS Homo sapiens
85 HIST1H2AJ 8331
Cross-Linking-MS (XL-MS) Homo sapiens
86 ZNF319  
Affinity Capture-MS Homo sapiens
87 DDX46 9879
Affinity Capture-MS Homo sapiens
88 CRB2 286204
Co-crystal Structure Homo sapiens
89 TMEM57  
Affinity Capture-MS Homo sapiens
90 HIST1H2AC 8334
Cross-Linking-MS (XL-MS) Homo sapiens
91 THOC3  
Affinity Capture-MS Homo sapiens
92 MTA1 9112
Affinity Capture-MS Homo sapiens
93 TCERG1 10915
Affinity Capture-MS Homo sapiens
94 KDM1B  
Affinity Capture-MS Homo sapiens
95 HIST1H2BC 8347
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
96 HIST1H2BN 8341
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
97 TBL3 10607
Affinity Capture-MS Homo sapiens
98 TRA2B 6434
Affinity Capture-MS Homo sapiens
99 ATF1  
Affinity Capture-MS Homo sapiens
100 PARP2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
101 EIF4B 1975
Affinity Capture-MS Homo sapiens
102 MXI1 4601
Affinity Capture-MS Homo sapiens
103 RAD21 5885
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
104 ZNF768 79724
Affinity Capture-MS Homo sapiens
105 EHMT1  
Affinity Capture-MS Homo sapiens
106 RPL23A 6147
Affinity Capture-MS Homo sapiens
107 NFIC 4782
Affinity Capture-MS Homo sapiens
108 UBN1  
Affinity Capture-MS Homo sapiens
109 PHF8  
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
110 LUC7L 55692
Affinity Capture-MS Homo sapiens
111 NDUFS6  
Affinity Capture-MS Homo sapiens
112 ZBTB44  
Affinity Capture-MS Homo sapiens
113 MCM3 4172
Affinity Capture-Western Homo sapiens
114 NCOA6  
Affinity Capture-MS Homo sapiens
115 HSPA6 3310
Affinity Capture-MS Homo sapiens
116 TMEM41B 440026
Affinity Capture-MS Homo sapiens
117 HIST1H4G 8369
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
118 ATG5 9474
Proximity Label-MS Homo sapiens
119 DNTTIP1 116092
Affinity Capture-MS Homo sapiens
120 BTF3 689
Affinity Capture-MS Homo sapiens
121 PRPF38A 84950
Affinity Capture-MS Homo sapiens
122 THRAP3 9967
Affinity Capture-MS Homo sapiens
123 USP39 10713
Affinity Capture-MS Homo sapiens
124 JUND 3727
Affinity Capture-MS Homo sapiens
125 RPL12 6136
Affinity Capture-MS Homo sapiens
126 CAND1 55832
Affinity Capture-MS Homo sapiens
127 SNRPF 6636
Affinity Capture-MS Homo sapiens
128 RPS18 6222
Affinity Capture-MS Homo sapiens
129 RPL32 6161
Affinity Capture-MS Homo sapiens
130 MBIP  
Affinity Capture-MS Homo sapiens
131 INO80B-WBP1  
Affinity Capture-MS Homo sapiens
132 RBM3 5935
Affinity Capture-MS Homo sapiens
133 DDX24 57062
Affinity Capture-MS Homo sapiens
134 H1FX 8971
Affinity Capture-MS Homo sapiens
135 CPSF4  
Affinity Capture-MS Homo sapiens
136 PHC3  
Affinity Capture-MS Homo sapiens
137 OSBP 5007
Co-fractionation Homo sapiens
138 MAGOHB 55110
Affinity Capture-MS Homo sapiens
139 KHDRBS1 10657
Affinity Capture-MS Homo sapiens
140 NUP93 9688
Affinity Capture-MS Homo sapiens
141 OBSL1 23363
Affinity Capture-MS Homo sapiens
142 RSRC1  
Affinity Capture-MS Homo sapiens
143 SUN2 25777
Affinity Capture-MS Homo sapiens
144 MSL2  
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
145 RBM42  
Affinity Capture-MS Homo sapiens
146 GSK3B 2932
Affinity Capture-MS Homo sapiens
147 GAR1 54433
Affinity Capture-MS Homo sapiens
148 TMEM201 199953
Affinity Capture-MS Homo sapiens
149 PAK1 5058
Biochemical Activity Homo sapiens
150 GTF2I 2969
Affinity Capture-MS Homo sapiens
151 JMJD6 23210
Co-fractionation Homo sapiens
152 SYMPK 8189
Affinity Capture-MS Homo sapiens
153 DDX21 9188
Affinity Capture-MS Homo sapiens
154 RPL4 6124
Affinity Capture-MS Homo sapiens
155 TRA2A 29896
Affinity Capture-MS Homo sapiens
156 JDP2  
Affinity Capture-MS Homo sapiens
157 NBN 4683
Affinity Capture-MS Homo sapiens
158 ACTA1 58
Affinity Capture-MS Homo sapiens
159 NCAPD3 23310
Affinity Capture-MS Homo sapiens
160 NKRF 55922
Affinity Capture-MS Homo sapiens
161 HIRA  
Affinity Capture-MS Homo sapiens
162 INTS7  
Affinity Capture-MS Homo sapiens
163 RAD18  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
164 TOX4  
Affinity Capture-MS Homo sapiens
165 SCAF11  
Affinity Capture-MS Homo sapiens
166 PREB 10113
Affinity Capture-MS Homo sapiens
167 SLFN5 162394
Affinity Capture-MS Homo sapiens
168 MAGOH 4116
Affinity Capture-MS Homo sapiens
169 ACTR10 55860
Cross-Linking-MS (XL-MS) Homo sapiens
170 ZNF609  
Affinity Capture-MS Homo sapiens
171 PAGE5  
Affinity Capture-MS Homo sapiens
172 CARS 833
Co-fractionation Homo sapiens
173 ELP3 55140
Biochemical Activity Homo sapiens
174 TPX2  
Affinity Capture-MS Homo sapiens
175 RECQL5  
Affinity Capture-MS Homo sapiens
176 MAP7 9053
Affinity Capture-MS Homo sapiens
177 LEO1 123169
Affinity Capture-MS Homo sapiens
178 TP53BP1 7158
Protein-peptide Homo sapiens
Co-crystal Structure Homo sapiens
Reconstituted Complex Homo sapiens
179 EIF6 3692
Affinity Capture-MS Homo sapiens
180 HIGD1A 25994
Affinity Capture-MS Homo sapiens
181 TUBB4B 10383
Affinity Capture-MS Homo sapiens
182 SYTL5 94122
Cross-Linking-MS (XL-MS) Homo sapiens
183 YLPM1 56252
Affinity Capture-MS Homo sapiens
184 CDK2 1017
Biochemical Activity Homo sapiens
185 TADA2A  
Affinity Capture-MS Homo sapiens
186 BUD31 8896
Affinity Capture-MS Homo sapiens
187 EHMT2 10919
Affinity Capture-MS Homo sapiens
188 DDB1 1642
Affinity Capture-MS Homo sapiens
189 DDRGK1 65992
Affinity Capture-MS Homo sapiens
190 FYTTD1  
Affinity Capture-MS Homo sapiens
191 ARGLU1  
Affinity Capture-MS Homo sapiens
192 TMEM209 84928
Affinity Capture-MS Homo sapiens
193 HMG20A  
Affinity Capture-MS Homo sapiens
194 HUWE1 10075
Cross-Linking-MS (XL-MS) Homo sapiens
195 DSP 1832
Affinity Capture-MS Homo sapiens
196 KLF13  
Affinity Capture-MS Homo sapiens
197 TAF6 6878
Affinity Capture-MS Homo sapiens
198 TERF2  
Affinity Capture-MS Homo sapiens
199 ILF3 3609
Affinity Capture-MS Homo sapiens
200 H3F3A 3020
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
201 ZNF221  
Affinity Capture-MS Homo sapiens
202 TMEM214 54867
Affinity Capture-MS Homo sapiens
203 NUCKS1 64710
Affinity Capture-MS Homo sapiens
204 SF3B4 10262
Affinity Capture-MS Homo sapiens
205 HLTF  
Affinity Capture-MS Homo sapiens
206 KNOP1 400506
Affinity Capture-MS Homo sapiens
207 PTBP1 5725
Affinity Capture-MS Homo sapiens
208 MED6  
Affinity Capture-MS Homo sapiens
209 CENPF 1063
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-MS Homo sapiens
210 EPC1  
Affinity Capture-MS Homo sapiens
211 ZNF281  
Affinity Capture-MS Homo sapiens
212 BUB3 9184
Affinity Capture-MS Homo sapiens
213 CDK1 983
Biochemical Activity Homo sapiens
214 RAD50 10111
Affinity Capture-MS Homo sapiens
215 OSBPL3 26031
Affinity Capture-MS Homo sapiens
216 DHX38 9785
Affinity Capture-MS Homo sapiens
217 YBX3 8531
Co-fractionation Homo sapiens
218 KAT6A  
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
219 CKAP4 10970
Affinity Capture-MS Homo sapiens
220 PRMT1 3276
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
221 ZBTB7A 51341
Affinity Capture-MS Homo sapiens
222 CUL4A 8451
Affinity Capture-MS Homo sapiens
223 CEBPZ  
Affinity Capture-MS Homo sapiens
224 SENP3 26168
Affinity Capture-MS Homo sapiens
225 GATAD2B 57459
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
226 TCEB1 6921
Affinity Capture-MS Homo sapiens
227 DHCR24 1718
Affinity Capture-MS Homo sapiens
228 CBLL1  
Affinity Capture-MS Homo sapiens
229 H2AFJ 55766
Cross-Linking-MS (XL-MS) Homo sapiens
230 SSB 6741
Co-fractionation Homo sapiens
231 C14orf93  
Affinity Capture-MS Homo sapiens
232 HNRNPR 10236
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
233 RPL10A 4736
Affinity Capture-MS Homo sapiens
234 TRIM28 10155
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
235 RFXANK  
Affinity Capture-MS Homo sapiens
236 KDM2A  
Affinity Capture-MS Homo sapiens
237 KMT2D 8085
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
238 SF3A2 8175
Affinity Capture-MS Homo sapiens
239 SRP14 6727
Affinity Capture-MS Homo sapiens
240 BCORL1  
Affinity Capture-MS Homo sapiens
241 CYLD  
Affinity Capture-MS Homo sapiens
242 RBM8A 9939
Affinity Capture-MS Homo sapiens
243 HSPA8 3312
Affinity Capture-MS Homo sapiens
244 GATA6  
Affinity Capture-MS Homo sapiens
245 PTGES2 80142
Cross-Linking-MS (XL-MS) Homo sapiens
246 BANP  
Affinity Capture-MS Homo sapiens
247 RAD23B 5887
Affinity Capture-MS Homo sapiens
248 MYO18A 399687
Cross-Linking-MS (XL-MS) Homo sapiens
249 SCAF1  
Affinity Capture-MS Homo sapiens
250 BAZ2B  
Affinity Capture-MS Homo sapiens
251 PNKP 11284
Affinity Capture-MS Homo sapiens
252 TUBA1A 7846
Affinity Capture-MS Homo sapiens
253 PCCA 5095
Affinity Capture-MS Homo sapiens
254 SAFB2 9667
Affinity Capture-MS Homo sapiens
255 BARD1 580
Affinity Capture-MS Homo sapiens
256 ARNT 405
Affinity Capture-MS Homo sapiens
257 RPL13A 23521
Affinity Capture-MS Homo sapiens
258 SNRPN 6638
Affinity Capture-MS Homo sapiens
259 ENY2 56943
Affinity Capture-MS Homo sapiens
260 TECR 9524
Affinity Capture-MS Homo sapiens
261 PELP1 27043
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
262 NKTR  
Affinity Capture-MS Homo sapiens
263 NECAP1 25977
Affinity Capture-MS Homo sapiens
264 REST 5978
Affinity Capture-MS Homo sapiens
265 RYBP  
Affinity Capture-MS Homo sapiens
266 SF3A3 10946
Affinity Capture-MS Homo sapiens
267 PCBP2 5094
Affinity Capture-MS Homo sapiens
268 RBBP6 5930
Affinity Capture-MS Homo sapiens
269 SF3B2 10992
Affinity Capture-MS Homo sapiens
270 MYH8 4626
Affinity Capture-MS Homo sapiens
271 MSH2 4436
Affinity Capture-MS Homo sapiens
272 BAZ1B 9031
Affinity Capture-MS Homo sapiens
273 ECT2 1894
Affinity Capture-MS Homo sapiens
274 RPRD2  
Affinity Capture-MS Homo sapiens
275 PHF2  
Affinity Capture-MS Homo sapiens
276 ISG20L2 81875
Affinity Capture-MS Homo sapiens
277 ZC3H8  
Affinity Capture-MS Homo sapiens
278 YY1 7528
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
279 TFPT  
Affinity Capture-MS Homo sapiens
280 YIPF5 81555
Affinity Capture-MS Homo sapiens
281 RFC1 5981
Affinity Capture-MS Homo sapiens
282 PRPF19 27339
Affinity Capture-MS Homo sapiens
283 RPS13 6207
Affinity Capture-MS Homo sapiens
284 EXOSC3 51010
Affinity Capture-MS Homo sapiens
285 INO80  
Affinity Capture-MS Homo sapiens
286 TOP1 7150
Affinity Capture-MS Homo sapiens
287 NHP2L1 4809
Affinity Capture-MS Homo sapiens
288 JUNB  
Affinity Capture-MS Homo sapiens
289 SKIV2L2 23517
Affinity Capture-MS Homo sapiens
290 DIDO1  
Affinity Capture-MS Homo sapiens
291 KTN1 3895
Affinity Capture-MS Homo sapiens
292 pr-set7  
Biochemical Activity Drosophila melanogaster
293 FOXK1 221937
Affinity Capture-MS Homo sapiens
294 RBM17 84991
Affinity Capture-MS Homo sapiens
295 SUMO1 7341
Affinity Capture-MS Homo sapiens
296 HIF1A 3091
Affinity Capture-MS Homo sapiens
297 FBXL6  
Affinity Capture-MS Homo sapiens
298 MCM5 4174
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
299 CHAMP1  
Affinity Capture-MS Homo sapiens
300 MEN1 4221
Affinity Capture-MS Homo sapiens
301 CREBBP  
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
302 LOC102724334 102724334
Cross-Linking-MS (XL-MS) Homo sapiens
303 FAM175A  
Affinity Capture-MS Homo sapiens
304 MKI67  
Affinity Capture-MS Homo sapiens
305 EIF1AX 1964
Cross-Linking-MS (XL-MS) Homo sapiens
306 INO80C  
Affinity Capture-MS Homo sapiens
307 UFL1 23376
Affinity Capture-MS Homo sapiens
308 HOXA11  
Affinity Capture-MS Homo sapiens
309 SNIP1  
Affinity Capture-MS Homo sapiens
310 GTPBP4 23560
Affinity Capture-MS Homo sapiens
311 RPRD1B 58490
Affinity Capture-MS Homo sapiens
312 ZC3H13 23091
Affinity Capture-MS Homo sapiens
313 SSRP1 6749
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
314 VPS72  
Affinity Capture-MS Homo sapiens
315 NOL9 79707
Affinity Capture-MS Homo sapiens
316 LUC7L3 51747
Affinity Capture-MS Homo sapiens
317 MAFK 7975
Affinity Capture-MS Homo sapiens
318 ARID5B 84159
Affinity Capture-MS Homo sapiens
319 RPS3A 6189
Affinity Capture-MS Homo sapiens
320 TNRC18  
Cross-Linking-MS (XL-MS) Homo sapiens
321 THOC2 57187
Affinity Capture-MS Homo sapiens
322 HIRIP3  
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
323 KARS 3735
Affinity Capture-MS Homo sapiens
324 NR2C2  
Affinity Capture-MS Homo sapiens
325 MSH3 4437
Affinity Capture-MS Homo sapiens
326 TAF5  
Affinity Capture-MS Homo sapiens
327 ANKRD18B 441459
Cross-Linking-MS (XL-MS) Homo sapiens
328 PAX6  
Affinity Capture-MS Homo sapiens
329 CDCA7L  
Affinity Capture-MS Homo sapiens
330 RPS20 6224
Affinity Capture-MS Homo sapiens
331 ERF  
Affinity Capture-MS Homo sapiens
332 TFAM 7019
Affinity Capture-MS Homo sapiens
333 USP3 9960
Affinity Capture-MS Homo sapiens
334 POLR2I 5438
Affinity Capture-MS Homo sapiens
335 ZSCAN21  
Affinity Capture-MS Homo sapiens
336 SNRPC 6631
Affinity Capture-MS Homo sapiens
337 TEAD1  
Affinity Capture-MS Homo sapiens
338 INO80E  
Affinity Capture-MS Homo sapiens
339 BCOR  
Affinity Capture-MS Homo sapiens
340 ANAPC7 51434
Affinity Capture-MS Homo sapiens
341 EXOSC6 118460
Affinity Capture-MS Homo sapiens
342 SEC23A 10484
Co-fractionation Homo sapiens
343 SSR3 6747
Affinity Capture-MS Homo sapiens
344 MLLT1 4298
Affinity Capture-MS Homo sapiens
345 CHD3 1107
Affinity Capture-MS Homo sapiens
346 WRN 7486
Affinity Capture-MS Homo sapiens
347 SETD8  
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Co-crystal Structure Homo sapiens
Co-crystal Structure Homo sapiens
Protein-peptide Homo sapiens
Co-crystal Structure Homo sapiens
348 HMGA1 3159
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
349 STRA13  
Affinity Capture-MS Homo sapiens
350 A2M 2
Cross-Linking-MS (XL-MS) Homo sapiens
351 ATF2  
Affinity Capture-MS Homo sapiens
352 UBE2I 7329
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
353 DDX5 1655
Affinity Capture-MS Homo sapiens
354 ANAPC10  
Affinity Capture-MS Homo sapiens
355 PML 5371
Co-localization Homo sapiens
356 PABPN1 8106
Affinity Capture-MS Homo sapiens
357 ZFC3H1 196441
Affinity Capture-MS Homo sapiens
358 EED  
Affinity Capture-MS Homo sapiens
359 MYH3 4621
Cross-Linking-MS (XL-MS) Homo sapiens
360 PRPF31 26121
Affinity Capture-MS Homo sapiens
361 ARID4A  
Affinity Capture-MS Homo sapiens
362 ING2  
Affinity Capture-MS Homo sapiens
363 WDR82 80335
Affinity Capture-MS Homo sapiens
364 RRP8  
Affinity Capture-MS Homo sapiens
365 SFPQ 6421
Affinity Capture-MS Homo sapiens
366 TAF15 8148
Affinity Capture-MS Homo sapiens
367 RPLP2 6181
Affinity Capture-MS Homo sapiens
368 FANCD2  
Affinity Capture-MS Homo sapiens
369 RPL7A 6130
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
370 POLR2H 5437
Affinity Capture-MS Homo sapiens
371 NDUFB10 4716
Affinity Capture-MS Homo sapiens
372 PNN 5411
Affinity Capture-MS Homo sapiens
373 RPL35 11224
Affinity Capture-MS Homo sapiens
374 NAT10 55226
Affinity Capture-MS Homo sapiens
375 ATP5H 10476
Affinity Capture-MS Homo sapiens
376 RFC2 5982
Affinity Capture-MS Homo sapiens
377 HCFC1 3054
Affinity Capture-MS Homo sapiens
378 SAP30BP  
Affinity Capture-MS Homo sapiens
379 XAB2 56949
Affinity Capture-MS Homo sapiens
380 ADNP 23394
Affinity Capture-MS Homo sapiens
381 CEBPG  
Affinity Capture-MS Homo sapiens
382 NXF1 10482
Affinity Capture-MS Homo sapiens
383 SF3A1 10291
Affinity Capture-MS Homo sapiens
384 AKAP8  
Affinity Capture-MS Homo sapiens
385 AP2A1 160
Affinity Capture-MS Homo sapiens
386 AAAS 8086
Affinity Capture-MS Homo sapiens
387 EPN1 29924
Affinity Capture-MS Homo sapiens
388 MMS22L  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
389 NR2F1  
Affinity Capture-MS Homo sapiens
390 COL13A1 1305
Cross-Linking-MS (XL-MS) Homo sapiens
391 WAC  
Affinity Capture-MS Homo sapiens
392 UBQLN4 56893
Affinity Capture-MS Homo sapiens
393 KAT2A  
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
394 NUP133 55746
Affinity Capture-MS Homo sapiens
395 PHRF1  
Affinity Capture-MS Homo sapiens
396 PITX1  
Affinity Capture-MS Homo sapiens
397 ZNF48  
Affinity Capture-MS Homo sapiens
398 CREB1  
Affinity Capture-MS Homo sapiens
399 CWC15  
Affinity Capture-MS Homo sapiens
400 PRR12 57479
Affinity Capture-MS Homo sapiens
401 THAP7  
Reconstituted Complex Homo sapiens
402 ANAPC2 29882
Affinity Capture-MS Homo sapiens
403 MCPH1  
Affinity Capture-MS Homo sapiens
404 TERF1 7013
Affinity Capture-MS Homo sapiens
405 TAPBP 6892
Affinity Capture-MS Homo sapiens
406 EZH2  
Affinity Capture-MS Homo sapiens
407 EYA4 2070
Affinity Capture-MS Homo sapiens
408 RPL23 9349
Affinity Capture-MS Homo sapiens
409 PRPF6 24148
Affinity Capture-MS Homo sapiens
410 ZNF629 23361
Affinity Capture-MS Homo sapiens
411 ZBTB20 26137
Affinity Capture-MS Homo sapiens
412 HNRNPU 3192
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
413 GNB2L1 10399
Affinity Capture-Western Homo sapiens
414 SS18L2  
Affinity Capture-MS Homo sapiens
415 CHAF1B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
416 ZNF146  
Affinity Capture-MS Homo sapiens
417 PPP1CB 5500
Affinity Capture-MS Homo sapiens
418 HDAC2 3066
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
419 SKI 6497
Affinity Capture-MS Homo sapiens
420 HIST1H2BH 8345
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
421 ZZZ3  
Affinity Capture-MS Homo sapiens
422 BRD2  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
FRET Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
FRET Homo sapiens
Protein-peptide Homo sapiens
Affinity Capture-MS Homo sapiens
423 SCAF4 57466
Affinity Capture-MS Homo sapiens
424 RBM15B  
Affinity Capture-MS Homo sapiens
425 PRPF40A 55660
Affinity Capture-MS Homo sapiens
426 CENPA  
Co-purification Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
427 CPSF2 53981
Affinity Capture-MS Homo sapiens
428 GPATCH4 54865
Affinity Capture-MS Homo sapiens
429 HDAC3 8841
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
430 DHX33  
Affinity Capture-MS Homo sapiens
431 CHAF1A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
432 CPSF7 79869
Affinity Capture-MS Homo sapiens
433 HSPH1 10808
Co-fractionation Homo sapiens
434 FAM207A  
Affinity Capture-MS Homo sapiens
435 CENPQ  
Affinity Capture-MS Homo sapiens
436 HMG20B  
Affinity Capture-MS Homo sapiens
437 ZBTB14  
Affinity Capture-MS Homo sapiens
438 ANAPC16  
Affinity Capture-MS Homo sapiens
439 C12orf43  
Affinity Capture-MS Homo sapiens
440 RPS11 6205
Affinity Capture-MS Homo sapiens
441 RCOR3  
Affinity Capture-MS Homo sapiens
442 MTA2 9219
Affinity Capture-MS Homo sapiens
443 MYL6 4637
Affinity Capture-MS Homo sapiens
444 TFAP2A  
Affinity Capture-MS Homo sapiens
445 ZYX 7791
Co-fractionation Homo sapiens
446 SRBD1  
Affinity Capture-MS Homo sapiens
447 RNF4 6047
Affinity Capture-MS Homo sapiens
448 MRE11A 4361
Affinity Capture-MS Homo sapiens
449 PELO 53918
Cross-Linking-MS (XL-MS) Homo sapiens
450 ZNF395 55893
Affinity Capture-MS Homo sapiens
451 HIST1H3E 8353
Affinity Capture-MS Homo sapiens
452 RPL18A 6142
Affinity Capture-MS Homo sapiens
453 CIRH1A 84916
Affinity Capture-MS Homo sapiens
454 SP1  
Affinity Capture-MS Homo sapiens
455 TTN 7273
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
456 SLX4  
Affinity Capture-MS Homo sapiens
457 CBX5 23468
Affinity Capture-MS Homo sapiens
458 SON 6651
Affinity Capture-MS Homo sapiens
459 DDX39B 7919
Affinity Capture-MS Homo sapiens
460 STAG2 10735
Affinity Capture-MS Homo sapiens
461 ACD  
Affinity Capture-MS Homo sapiens
462 RING1 6015
Affinity Capture-MS Homo sapiens
463 SMYD5 10322
Biochemical Activity Homo sapiens
464 RNF40 9810
Affinity Capture-MS Homo sapiens
465 ZBTB17  
Affinity Capture-MS Homo sapiens
466 MCCC2 64087
Affinity Capture-MS Homo sapiens
467 BKRF4  
Affinity Capture-MS
Reconstituted Complex
468 USP36  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
469 CUL3 8452
Affinity Capture-MS Homo sapiens
470 EBNA1BP2 10969
Affinity Capture-MS Homo sapiens
471 TTF2 8458
Affinity Capture-MS Homo sapiens
472 GTF3C4 9329
Affinity Capture-MS Homo sapiens
473 WDR43 23160
Affinity Capture-MS Homo sapiens
474 FANCA  
Affinity Capture-MS Homo sapiens
475 MFAP1  
Affinity Capture-MS Homo sapiens
476 ESCO1  
Affinity Capture-MS Homo sapiens
477 TIMM8B 26521
Affinity Capture-MS Homo sapiens
478 PHF5A 84844
Affinity Capture-MS Homo sapiens
479 TBL1X 6907
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
480 ZNF687  
Affinity Capture-MS Homo sapiens
481 PATZ1  
Affinity Capture-MS Homo sapiens
482 HAT1 8520
Co-crystal Structure Homo sapiens
Biochemical Activity Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
483 INTS5 80789
Affinity Capture-MS Homo sapiens
484 PYHIN1  
Affinity Capture-MS Homo sapiens
485 GNL3 26354
Affinity Capture-MS Homo sapiens
486 U2SURP 23350
Affinity Capture-MS Homo sapiens
487 PAXBP1  
Affinity Capture-MS Homo sapiens
488 DNALI1  
Cross-Linking-MS (XL-MS) Homo sapiens
489 PEX11B 8799
Affinity Capture-MS Homo sapiens
490 SUPT20H 55578
Affinity Capture-MS Homo sapiens
491 RBM25 58517
Affinity Capture-MS Homo sapiens
492 SKP1 6500
Affinity Capture-MS Homo sapiens
493 CDC6  
Affinity Capture-MS Homo sapiens
494 ITPR3 3710
Affinity Capture-MS Homo sapiens
495 H2AFY 9555
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
496 DYNC1H1 1778
Cross-Linking-MS (XL-MS) Homo sapiens
497 RABL3 285282
Affinity Capture-MS Homo sapiens
498 ALYREF 10189
Affinity Capture-MS Homo sapiens
499 HNRNPL 3191
Affinity Capture-MS Homo sapiens
500 ZNF205 7755
Affinity Capture-MS Homo sapiens
501 PCGF6  
Affinity Capture-MS Homo sapiens
502 ACACB 32
Affinity Capture-MS Homo sapiens
503 PRPF4 9128
Affinity Capture-MS Homo sapiens
504 CUL7 9820
Affinity Capture-MS Homo sapiens
505 GATAD1  
Affinity Capture-MS Homo sapiens
506 ANXA2 302
Affinity Capture-MS Homo sapiens
507 SNRPA1 6627
Affinity Capture-MS Homo sapiens
508 DNMT1 1786
Affinity Capture-MS Homo sapiens
509 NOP10 55505
Affinity Capture-MS Homo sapiens
510 HNRNPH1 3187
Affinity Capture-MS Homo sapiens
511 CCAR1 55749
Affinity Capture-MS Homo sapiens
512 LUZP4  
Affinity Capture-MS Homo sapiens
513 FRG1 2483
Affinity Capture-MS Homo sapiens
514 TRRAP 8295
Affinity Capture-MS Homo sapiens
515 HDGFRP2 84717
Affinity Capture-MS Homo sapiens
516 TARDBP 23435
Affinity Capture-MS Homo sapiens
517 NUP62 23636
Affinity Capture-MS Homo sapiens
518 ANAPC15  
Affinity Capture-MS Homo sapiens
519 RPL14 9045
Affinity Capture-MS Homo sapiens
520 HOXC10  
Affinity Capture-MS Homo sapiens
521 SRSF2 6427
Affinity Capture-MS Homo sapiens
522 PSIP1 11168
Affinity Capture-MS Homo sapiens
523 RNPS1 10921
Affinity Capture-MS Homo sapiens
524 HNRNPUL2-BSCL2  
Affinity Capture-MS Homo sapiens
525 NOLC1 9221
Affinity Capture-MS Homo sapiens
526 MITF  
Affinity Capture-MS Homo sapiens
527 MPHOSPH8 54737
Affinity Capture-MS Homo sapiens
528 BRWD3  
Affinity Capture-MS Homo sapiens
529 ELOVL1 64834
Affinity Capture-MS Homo sapiens
530 NPM1 4869
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
531 TINF2  
Affinity Capture-MS Homo sapiens
532 MDC1  
Affinity Capture-MS Homo sapiens
533 KLF4  
Affinity Capture-MS Homo sapiens
534 ZNF644  
Affinity Capture-MS Homo sapiens
535 NSD1  
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
536 CUL1 8454
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
537 USP7 7874
Affinity Capture-MS Homo sapiens
538 DLGAP5  
Affinity Capture-MS Homo sapiens
539 PRPF8 10594
Affinity Capture-MS Homo sapiens
540 RBX1 9978
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
541 PHB 5245
Affinity Capture-MS Homo sapiens
542 STOM 2040
Affinity Capture-MS Homo sapiens
543 NOL11  
Affinity Capture-MS Homo sapiens
544 TRIM24  
Co-crystal Structure Homo sapiens
Affinity Capture-MS Homo sapiens
545 EFHD2 79180
Cross-Linking-MS (XL-MS) Homo sapiens
546 VRK1 7443
Affinity Capture-MS Homo sapiens
547 HIST2H2BF 440689
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
548 NFIA 4774
Affinity Capture-MS Homo sapiens
549 RLIM 51132
Affinity Capture-MS Homo sapiens
550 RBMX2  
Affinity Capture-MS Homo sapiens
551 SUPT3H  
Affinity Capture-MS Homo sapiens
552 MBD2 8932
Affinity Capture-MS Homo sapiens
553 DCLRE1B  
Affinity Capture-MS Homo sapiens
554 APTX  
Affinity Capture-MS Homo sapiens
555 POLB 5423
Affinity Capture-MS Homo sapiens
556 AIMP2 7965
Affinity Capture-MS Homo sapiens
557 C7orf50 84310
Affinity Capture-MS Homo sapiens
558 UTP20 27340
Affinity Capture-MS Homo sapiens
559 TET3  
Affinity Capture-MS Homo sapiens
560 CHRAC1  
Affinity Capture-MS Homo sapiens
561 SMCHD1 23347
Affinity Capture-MS Homo sapiens
562 RPS2 6187
Affinity Capture-MS Homo sapiens
563 POP1 10940
Affinity Capture-MS Homo sapiens
564 SLC27A4 10999
Affinity Capture-MS Homo sapiens
565 NUP88 4927
Affinity Capture-MS Homo sapiens
566 CSRP2BP  
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
567 SRSF5 6430
Affinity Capture-MS Homo sapiens
568 FUS 2521
Affinity Capture-MS Homo sapiens
569 MORF4L1  
Affinity Capture-MS Homo sapiens
570 SLC7A5 8140
Affinity Capture-MS Homo sapiens
571 DMAP1 55929
Affinity Capture-MS Homo sapiens
572 HIST1H2AH 85235
Cross-Linking-MS (XL-MS) Homo sapiens
573 BAG1 573
Affinity Capture-MS Homo sapiens
574 EI24  
Affinity Capture-MS Homo sapiens
575 ACTR8 93973
Affinity Capture-MS Homo sapiens
576 HNRNPAB 3182
Affinity Capture-MS Homo sapiens
577 HIST1H1T 3010
Affinity Capture-MS Homo sapiens
578 FTSJ3 117246
Affinity Capture-MS Homo sapiens
579 TAF4 6874
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
580 RAE1 8480
Affinity Capture-MS Homo sapiens
581 GATAD2A 54815
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
582 KRT18 3875
Affinity Capture-MS Homo sapiens
583 CEP290  
Affinity Capture-MS Homo sapiens
584 POLR2F  
Affinity Capture-MS Homo sapiens
585 HDGF 3068
Affinity Capture-MS Homo sapiens
586 HMGB1 3146
Affinity Capture-MS Homo sapiens
587 PHF3  
Affinity Capture-MS Homo sapiens
588 RPS12 6206
Affinity Capture-MS Homo sapiens
589 PRMT7  
Biochemical Activity Homo sapiens
590 TRIP12 9320
Affinity Capture-MS Homo sapiens
591 TFE3  
Affinity Capture-MS Homo sapiens
592 NOC2L 26155
Affinity Capture-MS Homo sapiens
593 EEF1A1P5 158078
Affinity Capture-MS Homo sapiens
594 MYPOP  
Affinity Capture-MS Homo sapiens
595 TCF3  
Affinity Capture-MS Homo sapiens
596 VAMP5 10791
Affinity Capture-MS Homo sapiens
597 ATP5C1 509
Affinity Capture-MS Homo sapiens
598 PHC2  
Affinity Capture-MS Homo sapiens
599 VIM 7431
Affinity Capture-MS Homo sapiens
600 RCOR1  
Affinity Capture-MS Homo sapiens
601 TIMM13 26517
Affinity Capture-MS Homo sapiens
602 ZNF668  
Affinity Capture-MS Homo sapiens
603 SNRPE 6635
Affinity Capture-MS Homo sapiens
604 ATF7  
Affinity Capture-MS Homo sapiens
605 ANAPC5 51433
Affinity Capture-MS Homo sapiens
606 GATA2  
Affinity Capture-MS Homo sapiens
607 HIST1H2BJ 8970
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
608 RPS19 6223
Affinity Capture-MS Homo sapiens
609 SAMD1  
Affinity Capture-MS Homo sapiens
610 PPP1R10  
Affinity Capture-MS Homo sapiens
611 INTS9 55756
Affinity Capture-MS Homo sapiens
612 KAT7  
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
613 RUVBL1 8607
Affinity Capture-MS Homo sapiens
614 TAF9 6880
Affinity Capture-MS Homo sapiens
615 HIST1H2BM 8342
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
616 ING3  
Affinity Capture-MS Homo sapiens
617 MCM6 4175
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
618 TFEB  
Affinity Capture-MS Homo sapiens
619 HCFC2  
Affinity Capture-MS Homo sapiens
620 USF2 7392
Affinity Capture-MS Homo sapiens
621 FKBP11 51303
Affinity Capture-MS Homo sapiens
622 HIST2H2AC 8338
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
623 RPL29 6159
Affinity Capture-MS Homo sapiens
624 MTDH 92140
Affinity Capture-MS Homo sapiens
625 NHP2 55651
Affinity Capture-MS Homo sapiens
626 TFCP2 7024
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
627 MSL3  
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
628 BRIX1 55299
Affinity Capture-MS Homo sapiens
629 CXXC1  
Affinity Capture-MS Homo sapiens
630 VEZF1  
Affinity Capture-MS Homo sapiens
631 ATP5A1 498
Affinity Capture-MS Homo sapiens
632 FOXC1  
Affinity Capture-MS Homo sapiens
633 TAF10 6881
Affinity Capture-MS Homo sapiens
634 PARK2  
Affinity Capture-MS Homo sapiens
635 GTF2IRD1  
Affinity Capture-MS Homo sapiens
636 PHF14 9678
Affinity Capture-MS Homo sapiens
637 SAMD4A 23034
Affinity Capture-MS Homo sapiens
638 NAA40  
Affinity Capture-MS Homo sapiens
639 PAM16  
Affinity Capture-MS Homo sapiens
640 MCM10 55388
Affinity Capture-MS Homo sapiens
641 ABCF2 10061
Affinity Capture-MS Homo sapiens
642 LRWD1  
Affinity Capture-MS Homo sapiens
643 CHMP4B 128866
Affinity Capture-MS Homo sapiens
644 U2AF2 11338
Affinity Capture-MS Homo sapiens
645 MYBL2 4605
Affinity Capture-MS Homo sapiens
646 RPLP1 6176
Affinity Capture-MS Homo sapiens
647 PARP10 84875
Biochemical Activity Homo sapiens
648 DHX9 1660
Affinity Capture-MS Homo sapiens
649 QKI 9444
Cross-Linking-MS (XL-MS) Homo sapiens
650 HIST1H2BK 85236
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
651 L3MBTL2  
Protein-peptide Homo sapiens
Protein-peptide Homo sapiens
Protein-peptide Homo sapiens
Affinity Capture-MS Homo sapiens
652 KDM5A  
Affinity Capture-MS Homo sapiens
653 RBM10  
Affinity Capture-MS Homo sapiens
654 HIST1H2AI 8329
Cross-Linking-MS (XL-MS) Homo sapiens
655 HNRNPDL 9987
Affinity Capture-MS Homo sapiens
656 TAF7  
Affinity Capture-MS Homo sapiens
657 MIER1  
Affinity Capture-MS Homo sapiens
658 SRPR 6734
Affinity Capture-MS Homo sapiens
659 CDC73  
Affinity Capture-MS Homo sapiens
660 FAM60A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
661 AHNAK 79026
Affinity Capture-MS Homo sapiens
662 DDB2  
Affinity Capture-MS Homo sapiens
663 OTX1  
Affinity Capture-MS Homo sapiens
664 TERF2IP 54386
Affinity Capture-MS Homo sapiens
665 PDCD4 27250
Cross-Linking-MS (XL-MS) Homo sapiens
666 CUL9  
Affinity Capture-MS Homo sapiens
667 RPL36 25873
Affinity Capture-MS Homo sapiens
668 MSL1 339287
Affinity Capture-MS Homo sapiens
669 CLASRP  
Affinity Capture-MS Homo sapiens
670 ACTB 60
Affinity Capture-MS Homo sapiens
671 GPATCH8  
Affinity Capture-MS Homo sapiens
672 RPN1 6184
Affinity Capture-MS Homo sapiens
673 RNF2  
Affinity Capture-MS Homo sapiens
674 BEND3  
Affinity Capture-MS Homo sapiens
675 SEH1L 81929
Affinity Capture-MS Homo sapiens
676 SFMBT1 51460
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
677 XRCC5 7520
Affinity Capture-MS Homo sapiens
678 PIGR 5284
Affinity Capture-MS Homo sapiens
679 DDX50 79009
Affinity Capture-MS Homo sapiens
680 FNBP4  
Affinity Capture-MS Homo sapiens
681 TOPBP1 11073
Affinity Capture-MS Homo sapiens
682 ASF1B  
Affinity Capture-MS Homo sapiens
683 RPA1 6117
Affinity Capture-MS Homo sapiens
684 SAFB 6294
Affinity Capture-MS Homo sapiens
685 HNRNPM 4670
Affinity Capture-MS Homo sapiens
686 PBRM1 55193
Protein-peptide Homo sapiens
Affinity Capture-MS Homo sapiens
687 HSPB1 3315
Affinity Capture-MS Homo sapiens
688 RBM15 64783
Affinity Capture-MS Homo sapiens
689 RAVER1 125950
Affinity Capture-MS Homo sapiens
690 HMGXB4 10042
Affinity Capture-MS Homo sapiens
691 AFG3L2 10939
Affinity Capture-MS Homo sapiens
692 LSM7  
Affinity Capture-MS Homo sapiens
693 HOXC9  
Affinity Capture-MS Homo sapiens
694 CDK13 8621
Affinity Capture-MS Homo sapiens
695 MYO1E 4643
Affinity Capture-MS Homo sapiens
696 TAF1C  
Affinity Capture-MS Homo sapiens
697 UHRF1 29128
Affinity Capture-MS Homo sapiens
698 CEBPD  
Affinity Capture-MS Homo sapiens
699 EP300 2033
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
700 PSME4 23198
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
701 RPL11 6135
Affinity Capture-MS Homo sapiens
702 INTS4  
Affinity Capture-MS Homo sapiens
703 MCRS1  
Affinity Capture-MS Homo sapiens
704 MPG 4350
Affinity Capture-MS Homo sapiens
705 ZNHIT1  
Affinity Capture-MS Homo sapiens
706 KMT2C 58508
Reconstituted Complex Homo sapiens
Co-crystal Structure Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
707 PAXIP1  
Affinity Capture-MS Homo sapiens
708 POT1  
Affinity Capture-MS Homo sapiens
709 VAPA 9218
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
710 TADA3  
Affinity Capture-MS Homo sapiens
711 ETAA1  
Affinity Capture-MS Homo sapiens
712 ZC3H14  
Affinity Capture-MS Homo sapiens
713 INTS10  
Affinity Capture-MS Homo sapiens
714 C17orf96  
Affinity Capture-MS Homo sapiens
715 WDR36 134430
Affinity Capture-MS Homo sapiens
716 ILF2 3608
Affinity Capture-MS Homo sapiens
717 JAZF1  
Affinity Capture-MS Homo sapiens
718 TMA16  
Affinity Capture-MS Homo sapiens
719 TOP2A 7153
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
720 ATP5D 513
Affinity Capture-MS Homo sapiens
721 COPS5 10987
Affinity Capture-MS Homo sapiens
722 ZNF512B  
Affinity Capture-MS Homo sapiens
723 ORC5  
Affinity Capture-MS Homo sapiens
724 AGPAT2  
Affinity Capture-MS Homo sapiens
725 XPO7 23039
Co-fractionation Homo sapiens
726 ATP5O 539
Affinity Capture-MS Homo sapiens
727 CDC27 996
Affinity Capture-MS Homo sapiens
728 INTS6 26512
Affinity Capture-MS Homo sapiens
729 RMI2  
Affinity Capture-MS Homo sapiens
730 CTCF  
Affinity Capture-MS Homo sapiens
731 RPS23 6228
Affinity Capture-MS Homo sapiens
732 CLOCK  
Affinity Capture-MS Homo sapiens
733 SRP9 6726
Affinity Capture-MS Homo sapiens
734 TREX1  
Affinity Capture-MS Homo sapiens
735 SRSF6 6431
Affinity Capture-MS Homo sapiens
736 SP110  
Affinity Capture-MS Homo sapiens
737 FOXK2  
Affinity Capture-MS Homo sapiens
738 ACTL6A 86
Affinity Capture-MS Homo sapiens
739 MLX  
Affinity Capture-MS Homo sapiens
740 HJURP  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
741 SMC1A 8243
Affinity Capture-MS Homo sapiens
742 EIF4G2 1982
Affinity Capture-MS Homo sapiens
743 CEBPA  
Protein-peptide Homo sapiens
Affinity Capture-MS Homo sapiens
744 ATP5B 506
Affinity Capture-MS Homo sapiens
745 SRSF11 9295
Affinity Capture-MS Homo sapiens
746 TOR1AIP1 26092
Affinity Capture-MS Homo sapiens
747 COPS2 9318
Reconstituted Complex Homo sapiens
748 PAGR1  
Affinity Capture-MS Homo sapiens
749 VAPB 9217
Affinity Capture-MS Homo sapiens
750 HIST2H3C 126961
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
751 GTF3C1  
Affinity Capture-MS Homo sapiens
752 RPL36A 6173
Affinity Capture-MS Homo sapiens
753 MRGBP  
Affinity Capture-MS Homo sapiens
754 MCM4 4173
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
755 BBX 56987
Affinity Capture-MS Homo sapiens
756 SUZ12  
Affinity Capture-MS Homo sapiens
757 JUN 3725
Affinity Capture-MS Homo sapiens
758 FBXO6 26270
Affinity Capture-MS Homo sapiens
759 DDX47 51202
Affinity Capture-MS Homo sapiens
760 HIST1H2BA 255626
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
761 DNAJC9 23234
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
762 RREB1 6239
Affinity Capture-MS Homo sapiens
763 FIP1L1 81608
Affinity Capture-MS Homo sapiens
764 SRSF10 10772
Affinity Capture-MS Homo sapiens
765 SCD 6319
Affinity Capture-MS Homo sapiens
766 SF3B3 23450
Affinity Capture-MS Homo sapiens
767 BRD3 8019
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-MS Homo sapiens
768 EXOSC10 5394
Affinity Capture-MS Homo sapiens
769 SIRT6  
Affinity Capture-MS Homo sapiens
770 RRBP1 6238
Affinity Capture-MS Homo sapiens
771 DOCK5 80005
Affinity Capture-MS Homo sapiens
772 POLR1C 9533
Affinity Capture-MS Homo sapiens
773 HMGN5 79366
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
774 DNAJA3 9093
Affinity Capture-MS Homo sapiens
775 LSM2 57819
Affinity Capture-MS Homo sapiens
776 INTS2  
Affinity Capture-MS Homo sapiens
777 ANAPC1 64682
Affinity Capture-MS Homo sapiens
778 ELAVL1 1994
Affinity Capture-MS Homo sapiens
779 HIST1H2BD 3017
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
780 ATP2A2 488
Affinity Capture-MS Homo sapiens
781 NUP98 4928
Affinity Capture-MS Homo sapiens
782 C19orf40  
Affinity Capture-MS Homo sapiens
783 MAU2  
Affinity Capture-MS Homo sapiens
784 SNRNP40 9410
Affinity Capture-MS Homo sapiens
785 APITD1  
Affinity Capture-MS Homo sapiens
786 ZNF106  
Affinity Capture-MS Homo sapiens
787 IPO4 79711
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
788 TRIP4 9325
Affinity Capture-MS Homo sapiens
789 SRSF7 6432
Affinity Capture-MS Homo sapiens
790 CBX8 57332
Affinity Capture-MS Homo sapiens
791 RPS8 6202
Affinity Capture-MS Homo sapiens
792 LSM6 11157
Affinity Capture-MS Homo sapiens
793 C9orf72  
Affinity Capture-MS Homo sapiens
794 USF1  
Affinity Capture-MS Homo sapiens
795 EXOSC1 51013
Affinity Capture-MS Homo sapiens
796 ZIC5  
Affinity Capture-MS Homo sapiens
797 HIST2H2BE 8349
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
798 CDCA2 157313
Affinity Capture-MS Homo sapiens
799 PQBP1  
Affinity Capture-MS Homo sapiens
800 MBTD1  
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
801 JMJD1C 221037
Affinity Capture-MS Homo sapiens
802 CCNB2  
Affinity Capture-MS Homo sapiens
803 SRPRB 58477
Affinity Capture-MS Homo sapiens
804 DDX17 10521
Affinity Capture-MS Homo sapiens
805