Gene description for XRCC6
Gene name X-ray repair complementing defective repair in Chinese hamster cells 6
Gene symbol XRCC6
Other names/aliases CTC75
CTCBF
G22P1
KU70
ML8
TLAA
Species Homo sapiens
 Database cross references - XRCC6
ExoCarta ExoCarta_2547
Vesiclepedia VP_2547
Entrez Gene 2547
HGNC 4055
MIM 152690
UniProt P12956  
 XRCC6 identified in sEVs derived from the following tissue/cell type
Bladder cancer cells 20224111    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Colorectal cancer cells 34887515    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 36706192    
Embryonic kidney cells 36706192    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Hepatocellular carcinoma cells 26054723    
Hepatocellular carcinoma cells 26054723    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Squamous carcinoma cells 20124223    
T lymphocytes 34108659    
Thymus 23844026    
 Gene ontology annotations for XRCC6
Molecular Function
    transcription cis-regulatory region binding GO:0000976 IDA
    DNA binding GO:0003677 NAS
    DNA helicase activity GO:0003678 IDA
    damaged DNA binding GO:0003684 IEA
    double-stranded DNA binding GO:0003690 IBA
    double-stranded telomeric DNA binding GO:0003691 IDA
    RNA binding GO:0003723 HDA
    protein binding GO:0005515 IPI
    ATP binding GO:0005524 IEA
    ATP-dependent activity, acting on DNA GO:0008094 IDA
    ATP hydrolysis activity GO:0016887 IDA
    cyclin binding GO:0030332 IPI
    telomeric DNA binding GO:0042162 IBA
    protein-containing complex binding GO:0044877 IPI
    DNA end binding GO:0045027 IDA
    5'-deoxyribose-5-phosphate lyase activity GO:0051575 IMP
    scaffold protein binding GO:0097110 IPI
Biological Process
    telomere maintenance GO:0000723 IBA
    telomere maintenance GO:0000723 TAS
    recombinational repair GO:0000725 NAS
    activation of innate immune response GO:0002218 IDA
    DNA ligation GO:0006266 TAS
    double-strand break repair via nonhomologous end joining GO:0006303 IBA
    double-strand break repair via nonhomologous end joining GO:0006303 IMP
    double-strand break repair via nonhomologous end joining GO:0006303 NAS
    double-strand break repair via nonhomologous end joining GO:0006303 TAS
    DNA duplex unwinding GO:0032508 IEA
    innate immune response GO:0045087 IEA
    positive regulation of lymphocyte differentiation GO:0045621 ISS
    positive regulation of protein kinase activity GO:0045860 IDA
    negative regulation of DNA-templated transcription GO:0045892 IMP
    positive regulation of DNA-templated transcription GO:0045893 IDA
    positive regulation of DNA-templated transcription GO:0045893 IMP
    positive regulation of transcription by RNA polymerase II GO:0045944 IMP
    regulation of smooth muscle cell proliferation GO:0048660 IMP
    cellular hyperosmotic salinity response GO:0071475 IEA
    cellular response to gamma radiation GO:0071480 IDA
    cellular response to X-ray GO:0071481 IEA
    double-strand break repair via classical nonhomologous end joining GO:0097680 IDA
Subcellular Localization
    chromosome, telomeric region GO:0000781 HDA
    nuclear telomere cap complex GO:0000783 TAS
    extracellular region GO:0005576 TAS
    nucleus GO:0005634 TAS
    nucleoplasm GO:0005654 IDA
    nucleoplasm GO:0005654 TAS
    transcription regulator complex GO:0005667 IDA
    nucleolus GO:0005730 IDA
    cytosol GO:0005829 TAS
    DNA-dependent protein kinase-DNA ligase 4 complex GO:0005958 IDA
    membrane GO:0016020 HDA
    protein-containing complex GO:0032991 IDA
    protein-DNA complex GO:0032993 IDA
    secretory granule lumen GO:0034774 TAS
    Ku70:Ku80 complex GO:0043564 IBA
    Ku70:Ku80 complex GO:0043564 IDA
    Ku70:Ku80 complex GO:0043564 IPI
    DNA-dependent protein kinase complex GO:0070418 IPI
    nonhomologous end joining complex GO:0070419 IDA
    ficolin-1-rich granule lumen GO:1904813 TAS
 Experiment description of studies that identified XRCC6 in sEVs
1
Experiment ID 76
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|GAPDH|HSP90|CD81|CD9|CD63|LAMP1|MHCI
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20224111    
Organism Homo sapiens
Experiment description Proteomics analysis of bladder cancer exosomes.
Authors "Welton JL, Khanna S, Giles PJ, Brennan P, Brewis IA, Staffurth J, Mason MD, Clayton A."
Journal name MCP
Publication year 2010
Sample Bladder cancer cells
Sample name HT1376
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.10-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF/TOF]
Western blotting
FACS
2
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
8
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
9
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
10
Experiment ID 494
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD151|CD63|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Osteoarthritic cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
11
Experiment ID 496
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Healthy cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
12
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
13
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
14
Experiment ID 207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
15
Experiment ID 208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
16
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
17
Experiment ID 282
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Ultracentrifugation - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
18
Experiment ID 283
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Ultracentrifugation - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
19
Experiment ID 285
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Sequential centrifugal ultrafiltration - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Sequential centrifugal ultrafiltration
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
20
Experiment ID 286
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Sequential centrifugal ultrafiltration - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Sequential centrifugal ultrafiltration
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
21
Experiment ID 1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
22
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
23
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
24
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
25
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
26
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
27
Experiment ID 1275
MISEV standards
Biophysical techniques
✔
CD9|TSG101|FLOT1|FLOT2|RAB35|RAB5A|GAPDH|TFRC|CD63|Alix
Enriched markers
✔
PCNA|CANX|GAPDH|HSP90AA1|HSP90B1
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
28
Experiment ID 1280
MISEV standards
Biophysical techniques
✔
TSG101|CD9|FLOT1|FLOT2|RAB35|RAB5A|GAPDH|TFRC|CD63|Alix
Enriched markers
✔
PCNA|CANX|GAPDH|HSP90AA1|HSP90B1
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T - Fraction 5
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density 1.151 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
29
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
30
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
31
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
32
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
33
Experiment ID 235
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
34
Experiment ID 236
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
35
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
36
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
37
Experiment ID 254
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name MNT-1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
38
Experiment ID 257
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name Daju
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
39
Experiment ID 259
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name A375M
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
40
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
41
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
42
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
43
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
44
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
45
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
46
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
47
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
48
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
49
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
50
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
51
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
52
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
53
Experiment ID 191
MISEV standards
✘ Biophysical techniques
✔
Alix|CD81|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
54
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
55
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for XRCC6
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HIST2H2BE 8349
Affinity Capture-MS Homo sapiens
2 CDCA2 157313
Proximity Label-MS Homo sapiens
3 NPEPPS 9520
Proximity Label-MS Homo sapiens
4 ISG15 9636
Affinity Capture-MS Homo sapiens
5 MACROD1 28992
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
6 PAEP  
Two-hybrid Homo sapiens
7 LANCL1 10314
Co-fractionation Homo sapiens
8 HACD3 51495
Co-fractionation Homo sapiens
9 CSNK1A1 1452
Affinity Capture-MS Homo sapiens
10 NFATC1 4772
Affinity Capture-MS Homo sapiens
11 UBA1 7317
Proximity Label-MS Homo sapiens
12 BRCA1 672
Affinity Capture-MS Homo sapiens
13 GTF2F1 2962
Proximity Label-MS Homo sapiens
14 UBE3A 7337
Affinity Capture-MS Homo sapiens
15 CSNK2A1 1457
Biochemical Activity Homo sapiens
16 LOC100132735  
Protein-RNA Homo sapiens
17 INTS1 26173
Proximity Label-MS Homo sapiens
18 PRPF40A 55660
Reconstituted Complex Homo sapiens
19 SOX2  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
20 CENPA  
Proximity Label-MS Homo sapiens
21 HAL 3034
Proximity Label-MS Homo sapiens
22 APEX1 328
Proximity Label-MS Homo sapiens
23 CUL7 9820
Affinity Capture-MS Homo sapiens
24 CENPU  
Two-hybrid Homo sapiens
25 IGF2BP3 10643
Affinity Capture-MS Homo sapiens
26 WDR76  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-purification Homo sapiens
27 KRT8 3856
Proximity Label-MS Homo sapiens
28 CHAF1A  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
29 KIF23 9493
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
30 NDRG1 10397
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
31 NIT1 4817
Two-hybrid Homo sapiens
32 HDLBP 3069
Co-fractionation Homo sapiens
33 H2AFV 94239
Proximity Label-MS Homo sapiens
34 AI837181  
Affinity Capture-MS Mus musculus
35 PSMD12 5718
Affinity Capture-MS Homo sapiens
36 FBL 2091
Proximity Label-MS Homo sapiens
37 ORC6  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
38 C20orf27 54976
Proximity Label-MS Homo sapiens
39 CHORDC1 26973
Proximity Label-MS Homo sapiens
40 MECP2 4204
Affinity Capture-MS Homo sapiens
41 CTNNA1 1495
Co-fractionation Homo sapiens
42 RNF126  
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
43 ICE1  
Cross-Linking-MS (XL-MS) Homo sapiens
44 CCT5 22948
Proximity Label-MS Homo sapiens
45 SOD1 6647
Affinity Capture-MS Homo sapiens
46 MTA2 9219
Co-fractionation Homo sapiens
47 RBM14 10432
Co-fractionation Homo sapiens
48 NEIL3  
Affinity Capture-MS Homo sapiens
49 KIF14 9928
Affinity Capture-MS Homo sapiens
50 EMC9  
Affinity Capture-MS Homo sapiens
51 TFAP2A  
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
52 XRCC4  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
53 CHMP4C 92421
Affinity Capture-MS Homo sapiens
54 LDHB 3945
Proximity Label-MS Homo sapiens
55 KIFC1 3833
Proximity Label-MS Homo sapiens
56 WBP4  
Reconstituted Complex Homo sapiens
57 VAV1 7409
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
58 UTP14A 10813
Proximity Label-MS Homo sapiens
59 SPTA1  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
60 USP11 8237
Affinity Capture-MS Homo sapiens
61 CLU 1191
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Far Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
62 SUPT5H 6829
Co-fractionation Homo sapiens
63 ILVBL 10994
Two-hybrid Homo sapiens
64 COPB1 1315
Two-hybrid Homo sapiens
65 RRAS2 22800
Two-hybrid Homo sapiens
66 SNTA1 6640
Two-hybrid Homo sapiens
67 FOXL2  
Affinity Capture-Western Homo sapiens
68 YAP1 10413
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
69 TRIM21 6737
Affinity Capture-MS Homo sapiens
70 OGT 8473
Reconstituted Complex Homo sapiens
71 RPL31 6160
Proximity Label-MS Homo sapiens
72 CBX5 23468
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
73 Mapk13  
Affinity Capture-MS Mus musculus
74 ENO1 2023
Affinity Capture-RNA Homo sapiens
Proximity Label-MS Homo sapiens
75 HECTD1 25831
Affinity Capture-MS Homo sapiens
76 CUL2 8453
Co-fractionation Homo sapiens
77 AHCTF1 25909
Proximity Label-MS Homo sapiens
78 VDAC2 7417
Proximity Label-MS Homo sapiens
79 BIN1 274
Co-purification Homo sapiens
80 CACYBP 27101
Proximity Label-MS Homo sapiens
81 MGMT 4255
Affinity Capture-MS Homo sapiens
82 CD3EAP  
Proximity Label-MS Homo sapiens
83 SCARNA22  
Affinity Capture-RNA Homo sapiens
84 ANLN 54443
Affinity Capture-MS Homo sapiens
85 SDHC 6391
Two-hybrid Homo sapiens
86 HSPA5 3309
Co-fractionation Homo sapiens
87 DDX46 9879
Proximity Label-MS Homo sapiens
88 RBM39 9584
Affinity Capture-MS Homo sapiens
89 KIF20A 10112
Affinity Capture-MS Homo sapiens
90 SDHA 6389
Co-fractionation Homo sapiens
91 BKRF4  
Affinity Capture-MS
92 SIRT7  
Affinity Capture-MS Homo sapiens
93 EPAS1  
Affinity Capture-Western Homo sapiens
94 Terf1  
Affinity Capture-MS Mus musculus
95 TAL1  
Affinity Capture-MS Homo sapiens
96 ANXA1 301
Two-hybrid Homo sapiens
Protein-peptide Homo sapiens
97 SKP2  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
98 YWHAZ 7534
Two-hybrid Homo sapiens
99 MAP2K5  
Two-hybrid Homo sapiens
100 ZNF250  
Proximity Label-MS Homo sapiens
101 EIF2S2 8894
Co-fractionation Homo sapiens
102 GZMA 3001
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
103 ZC3H11A  
Proximity Label-MS Homo sapiens
104 RBBP4 5928
Two-hybrid Homo sapiens
105 FN1 2335
Affinity Capture-MS Homo sapiens
106 THRA  
Affinity Capture-MS Homo sapiens
107 KRT15 3866
Proximity Label-MS Homo sapiens
108 FARSB 10056
Co-fractionation Homo sapiens
109 PCBP1 5093
Proximity Label-MS Homo sapiens
110 LIN54  
Proximity Label-MS Homo sapiens
111 TAC1  
Two-hybrid Homo sapiens
112 RPA3 6119
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
113 DLST 1743
Affinity Capture-MS Homo sapiens
114 HOXC4  
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
115 MED23 9439
Co-fractionation Homo sapiens
116 BTG1 694
Two-hybrid Homo sapiens
117 CSDE1 7812
Co-fractionation Homo sapiens
118 PLGRKT 55848
Two-hybrid Homo sapiens
119 DLAT 1737
Co-fractionation Homo sapiens
120 DPYSL3 1809
Co-fractionation Homo sapiens
121 APLF  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
122 SUPT16H 11198
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
123 PYHIN1  
Affinity Capture-MS Homo sapiens
124 PRKDC 5591
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
125 BIRC5  
Affinity Capture-Western Homo sapiens
126 STUB1 10273
Proximity Label-MS Homo sapiens
127 RASA1 5921
Two-hybrid Homo sapiens
128 TLX1  
Affinity Capture-MS Homo sapiens
129 RELA 5970
Co-fractionation Homo sapiens
130 RPS27A 6233
Proximity Label-MS Homo sapiens
131 SKIL  
Two-hybrid Homo sapiens
132 RUVBL2 10856
Proximity Label-MS Homo sapiens
133 TCERG1 10915
Proximity Label-MS Homo sapiens
134 ZEB1  
Affinity Capture-MS Homo sapiens
135 LRPPRC 10128
Co-fractionation Homo sapiens
136 IFI16 3428
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
137 HIST1H2BC 8347
Proximity Label-MS Homo sapiens
138 MTA1 9112
Proximity Label-MS Homo sapiens
139 DIMT1 27292
Affinity Capture-MS Homo sapiens
140 HSP90AA1 3320
Proximity Label-MS Homo sapiens
141 GTF2B 2959
Proximity Label-MS Homo sapiens
142 SSBP1 6742
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
143 PARP2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
144 NCL 4691
Reconstituted Complex Homo sapiens
145 PARS2 25973
Co-fractionation Homo sapiens
146 TGM1 7051
Proximity Label-MS Homo sapiens
147 GLTSCR2  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
148 ACO2 50
Affinity Capture-MS Homo sapiens
149 IMPDH1 3614
Co-fractionation Homo sapiens
150 HNF1B  
Affinity Capture-MS Homo sapiens
151 CHAMP1  
Proximity Label-MS Homo sapiens
152 PSMD3 5709
Affinity Capture-MS Homo sapiens
153 CDCA5  
Two-hybrid Homo sapiens
154 KIF9 64147
Cross-Linking-MS (XL-MS) Homo sapiens
155 LIG4 3981
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
156 ILKAP 80895
Proximity Label-MS Homo sapiens
157 NCOA6  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
158 LYZ 4069
Proximity Label-MS Homo sapiens
159 SEP15 9403
Two-hybrid Homo sapiens
160 GART 2618
Co-fractionation Homo sapiens
161 EIF2S3 1968
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
162 CTBP2 1488
Two-hybrid Homo sapiens
163 TARDBP 23435
Affinity Capture-MS Homo sapiens
164 RPA2 6118
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
165 HIST1H2BG 8339
Proximity Label-MS Homo sapiens
166 ALB 213
Proximity Label-MS Homo sapiens
167 CD40 958
Reconstituted Complex Homo sapiens
168 TERF2IP 54386
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
169 DLX2  
Reconstituted Complex Homo sapiens
170 ASXL1  
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
171 RPS18 6222
Proximity Label-MS Homo sapiens
172 PSIP1 11168
Cross-Linking-MS (XL-MS) Homo sapiens
173 XRCC1 7515
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
174 NR1H4  
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
175 NCOR1  
Proximity Label-MS Homo sapiens
176 DIAPH1 1729
Co-fractionation Homo sapiens
177 CAPN11  
Two-hybrid Homo sapiens
178 PRC1 9055
Affinity Capture-MS Homo sapiens
179 NPM1 4869
Co-fractionation Homo sapiens
180 SRRM2 23524
Affinity Capture-MS Homo sapiens
181 NARS 4677
Co-fractionation Homo sapiens
182 TINF2  
Affinity Capture-MS Homo sapiens
183 BAX 581
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
184 STIP1 10963
Proximity Label-MS Homo sapiens
185 C9orf142  
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
186 VCAM1 7412
Affinity Capture-MS Homo sapiens
187 NSD1  
Proximity Label-MS Homo sapiens
188 PHF1  
Affinity Capture-Western Homo sapiens
189 SMARCAD1  
Affinity Capture-MS Homo sapiens
190 PHF2  
Proximity Label-MS Homo sapiens
191 PRNP 5621
Affinity Capture-MS Homo sapiens
192 GTF2I 2969
Co-fractionation Homo sapiens
193 PFN1 5216
Proximity Label-MS Homo sapiens
194 GZMB  
Biochemical Activity Homo sapiens
195 VRK3 51231
Affinity Capture-MS Homo sapiens
196 NAE1 8883
Co-fractionation Homo sapiens
197 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
198 USP10 9100
Affinity Capture-MS Homo sapiens
199 WHSC1 7468
Proximity Label-MS Homo sapiens
200 MSX2  
Affinity Capture-Western Homo sapiens
201 NBN 4683
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
202 VRK1 7443
Affinity Capture-MS Homo sapiens
203 CFDP1  
Proximity Label-MS Homo sapiens
204 CCNB1 891
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
205 SNRPD1 6632
Proximity Label-MS Homo sapiens
206 AIM2  
Affinity Capture-MS Homo sapiens
207 PDHX 8050
Co-fractionation Homo sapiens
208 RTF1 23168
Proximity Label-MS Homo sapiens
209 CTNNB1 1499
Co-fractionation Homo sapiens
210 ADCY7 113
Two-hybrid Homo sapiens
211 PPM1G 5496
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
212 RPL36A 6173
Proximity Label-MS Homo sapiens
213 ATP6V1E1 529
Two-hybrid Homo sapiens
214 HERPUD1  
Two-hybrid Homo sapiens
215 HNRNPD 3184
Affinity Capture-MS Homo sapiens
216 PSMA3 5684
Affinity Capture-MS Homo sapiens
217 KHSRP 8570
Proximity Label-MS Homo sapiens
218 SMCHD1 23347
Proximity Label-MS Homo sapiens
219 CANX 821
Proximity Label-MS Homo sapiens
220 KCND3 3752
Affinity Capture-Western Homo sapiens
221 TP53BP1 7158
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
222 RC3H2  
Affinity Capture-MS Homo sapiens
223 IKZF3  
Affinity Capture-MS Homo sapiens
224 PPARG 5468
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
225 NCF4 4689
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
226 POU2F2 5452
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
227 EGFR 1956
Negative Genetic Homo sapiens
228 HSD17B10 3028
Affinity Capture-MS Homo sapiens
229 IKZF1  
Affinity Capture-MS Homo sapiens
230 SNF8 11267
Co-fractionation Homo sapiens
231 XRCC6BP1  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
232 WAPAL  
Proximity Label-MS Homo sapiens
233 SPTBN1 6711
Proximity Label-MS Homo sapiens
234 HIST1H3B 8358
Affinity Capture-MS Homo sapiens
235 CDK2 1017
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
Biochemical Activity Homo sapiens
236 RBM10  
Proximity Label-MS Homo sapiens
237 PIAS1 8554
Proximity Label-MS Homo sapiens
238 MYC  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
239 BAG1 573
Affinity Capture-MS Homo sapiens
240 DYNC1LI1 51143
Co-fractionation Homo sapiens
241 SET 6418
Co-fractionation Homo sapiens
Reconstituted Complex Homo sapiens
Proximity Label-MS Homo sapiens
242 PDX1  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
243 SART3 9733
Proximity Label-MS Homo sapiens
244 SNW1 22938
Affinity Capture-MS Homo sapiens
245 DDRGK1 65992
Affinity Capture-MS Homo sapiens
246 PGAM1 5223
Two-hybrid Homo sapiens
247 NFYA 4800
Co-fractionation Homo sapiens
248 LMNA 4000
Proximity Label-MS Homo sapiens
249 ADAR 103
Co-fractionation Homo sapiens
250 SIRT3  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
251 Rnf126  
Affinity Capture-Western Mus musculus
252 PHGDH 26227
Proximity Label-MS Homo sapiens
253 EIF3H 8667
Affinity Capture-MS Homo sapiens
254 RPL19 6143
Proximity Label-MS Homo sapiens
255 PA2G4 5036
Proximity Label-MS Homo sapiens
256 SLC25A3 5250
Proximity Label-MS Homo sapiens
257 TERF2  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
258 PARP1 142
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
259 GDI2 2665
Proximity Label-MS Homo sapiens
260 ILF3 3609
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
261 SMAD7  
Two-hybrid Homo sapiens
262 H3F3A 3020
Affinity Capture-MS Homo sapiens
263 TP53 7157
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
264 NMI  
Co-fractionation Homo sapiens
265 ABCD4 5826
Two-hybrid Homo sapiens
266 HDAC6 10013
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
267 RIF1  
Proximity Label-MS Homo sapiens
268 RPS4X 6191
Proximity Label-MS Homo sapiens
269 DSC1 1823
Proximity Label-MS Homo sapiens
270 SMAD4  
Co-fractionation Homo sapiens
271 FKBP4 2288
Proximity Label-MS Homo sapiens
272 SHMT2 6472
Affinity Capture-RNA Homo sapiens
273 CDK1 983
Biochemical Activity Homo sapiens
274 POU2F1 5451
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
275 ESR1  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
276 HEXIM1 10614
Co-fractionation Homo sapiens
277 FCHSD1 89848
Affinity Capture-MS Homo sapiens
278 DNTT 1791
Affinity Capture-Western Homo sapiens
279 ATP1A1 476
Proximity Label-MS Homo sapiens
280 DDX42 11325
Proximity Label-MS Homo sapiens
281 KRAS 3845
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
282 MAST3  
Affinity Capture-MS Homo sapiens
283 CDKN2AIP  
Proximity Label-MS Homo sapiens
284 ZBTB7A 51341
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
285 CUL4A 8451
Affinity Capture-MS Homo sapiens
286 CKB 1152
Proximity Label-MS Homo sapiens
287 RALY 22913
Proximity Label-MS Homo sapiens
288 ATP6V1B2 526
Co-fractionation Homo sapiens
289 XPC  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
290 UBE2H 7328
Affinity Capture-MS Homo sapiens
291 SLIRP 81892
Co-fractionation Homo sapiens
292 CMTM6 54918
Two-hybrid Homo sapiens
293 CBX1 10951
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
294 ORC4  
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
295 EEF1G 1937
Proximity Label-MS Homo sapiens
296 THRB 7068
Affinity Capture-MS Homo sapiens
297 RANBP3 8498
Co-fractionation Homo sapiens
298 LDHA 3939
Proximity Label-MS Homo sapiens
299 MAP4K2  
Two-hybrid Homo sapiens
300 TIMM50 92609
Proximity Label-MS Homo sapiens
301 RPS19 6223
Proximity Label-MS Homo sapiens
302 TCF7L2  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
303 ORC2  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
304 EPS8 2059
Two-hybrid Homo sapiens
305 MRE11A 4361
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
306 PGR  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
307 PEBP1 5037
Proximity Label-MS Homo sapiens
308 ATG13 9776
Affinity Capture-MS Homo sapiens
309 NUDCD2 134492
Proximity Label-MS Homo sapiens
310 CAPZB 832
Affinity Capture-MS Homo sapiens
311 RUVBL1 8607
Proximity Label-MS Homo sapiens
312 TRIM28 10155
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
Proximity Label-MS Homo sapiens
313 MAP1B 4131
Proximity Label-MS Homo sapiens
314 MCM2 4171
Affinity Capture-MS Homo sapiens
315 ACD  
Two-hybrid Homo sapiens
316 ZNF638 27332
Proximity Label-MS Homo sapiens
317 CCNA1  
Two-hybrid Homo sapiens
318 CDK12 51755
Proximity Label-MS Homo sapiens
319 MDC1  
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
320 HMGA2 8091
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
321 ITGA4 3676
Affinity Capture-MS Homo sapiens
322 ATRX 546
Affinity Capture-MS Homo sapiens
323 ATG16L1 55054
Affinity Capture-MS Homo sapiens
324 PIAS2  
Proximity Label-MS Homo sapiens
325 TUBA1A 7846
Proximity Label-MS Homo sapiens
326 TFCP2 7024
Affinity Capture-MS Homo sapiens
327 SERBP1 26135
Affinity Capture-MS Homo sapiens
328 CFLAR  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
329 YAF2  
Affinity Capture-MS Homo sapiens
330 SAMHD1 25939
Co-fractionation Homo sapiens
331 SERPINB9 5272
Two-hybrid Homo sapiens
Proximity Label-MS Homo sapiens
332 MED1 5469
Proximity Label-MS Homo sapiens
333 NF2 4771
Affinity Capture-MS Homo sapiens
334 BANP  
Affinity Capture-Western Homo sapiens
335 NSUN2 54888
Proximity Label-MS Homo sapiens
336 DLD 1738
Affinity Capture-MS Homo sapiens
337 RGS2  
Two-hybrid Homo sapiens
338 HIST1H3E 8353
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-purification Homo sapiens
339 PARK2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
340 PNKP 11284
Affinity Capture-MS Homo sapiens
341 RPS10 6204
Two-hybrid Homo sapiens
342 ARG1 383
Proximity Label-MS Homo sapiens
343 SPARC 6678
Two-hybrid Homo sapiens
344 CBX3 11335
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
345 PLOD2 5352
Co-fractionation Homo sapiens
346 CHMP4B 128866
Affinity Capture-MS Homo sapiens
347 BTF3 689
Affinity Capture-MS Homo sapiens
348 BARD1 580
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
349 NTRK1 4914
Affinity Capture-MS Homo sapiens
350 U2AF2 11338
Affinity Capture-MS Homo sapiens
351 ARNT 405
Affinity Capture-MS Homo sapiens
352 SUGT1 10910
Proximity Label-MS Homo sapiens
353 SMAD2 4087
Co-fractionation Homo sapiens
354 RPA4  
Proximity Label-MS Homo sapiens
355 RPLP1 6176
Two-hybrid Homo sapiens
356 TUBA1B 10376
Proximity Label-MS Homo sapiens
357 DHX9 1660
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
358 SLX4IP  
Affinity Capture-MS Homo sapiens
359 NUDC 10726
Proximity Label-MS Homo sapiens
360 HDAC5 10014
Affinity Capture-MS Homo sapiens
361 PECAM1 5175
Two-hybrid Homo sapiens
362 RAN 5901
Proximity Label-MS Homo sapiens
363 PCBP2 5094
Proximity Label-MS Homo sapiens
364 TONSL  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
365 GAL3ST4 79690
Two-hybrid Homo sapiens
366 METTL14  
Affinity Capture-MS Homo sapiens
367 MSH2 4436
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
368 BAZ1B 9031
Proximity Label-MS Homo sapiens
369 BAG2 9532
Affinity Capture-MS Homo sapiens
370 ECT2 1894
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
371 MGA  
Proximity Label-MS Homo sapiens
372 HIST1H2BB 3018
Proximity Label-MS Homo sapiens
373 CCDC57 284001
Affinity Capture-MS Homo sapiens
374 EEF2 1938
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
375 NFATC2  
Affinity Capture-MS Homo sapiens
376 TBX20 57057
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
377 SF1 7536
Proximity Label-MS Homo sapiens
378 DDB2  
Affinity Capture-Western Homo sapiens
379 UHRF2  
Affinity Capture-MS Homo sapiens
380 ZC3H4 23211
Proximity Label-MS Homo sapiens
381 YY1 7528
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
382 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
383 PDPK1 5170
Two-hybrid Homo sapiens
384 EMX2  
Affinity Capture-MS Homo sapiens
385 HOXD4  
Reconstituted Complex Homo sapiens
386 RFC1 5981
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
387 CAND1 55832
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
388 PSPC1 55269
Co-fractionation Homo sapiens
389 RUNX2  
Affinity Capture-Western Homo sapiens
390 TOP1 7150
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
391 NHP2L1 4809
Two-hybrid Homo sapiens
392 SIRT6  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
393 MATR3 9782
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
394 HYOU1 10525
Co-fractionation Homo sapiens
395 HSPD1 3329
Proximity Label-MS Homo sapiens
396 EHF  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
397 HSPA9 3313
Proximity Label-MS Homo sapiens
398 HDGF 3068
Affinity Capture-MS Homo sapiens
399 XRCC5 7520
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Co-fractionation Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-crystal Structure Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Proximity Label-MS Homo sapiens
400 RBBP8  
Affinity Capture-MS Homo sapiens
401 HIF1A 3091
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
402 TBX3 6926
Affinity Capture-MS Homo sapiens
403 AHSA1 10598
Affinity Capture-Western Homo sapiens
404 EIF2S1 1965
Co-fractionation Homo sapiens
405 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
406 PHB2 11331
Proximity Label-MS Homo sapiens
407 CCT8 10694
Proximity Label-MS Homo sapiens
408 MAX  
Co-fractionation Homo sapiens
409 HMGN4  
Affinity Capture-MS Homo sapiens
410 LIG3 3980
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
411 JUP 3728
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
412 CWC27 10283
Proximity Label-MS Homo sapiens
413 PIN1 5300
Reconstituted Complex Homo sapiens
414 KAT2B  
Biochemical Activity Homo sapiens
415 RPA1 6117
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
416 IKBKG 8517
Affinity Capture-Western Homo sapiens
417 EFNA1  
Two-hybrid Homo sapiens
418 HNRNPM 4670
Proximity Label-MS Homo sapiens
419 ABL1 25
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
420 PTTG1  
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
421 CREBBP  
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
422 CHD1L 9557
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
423 MTHFD1 4522
Proximity Label-MS Homo sapiens
424 GPKOW  
Proximity Label-MS Homo sapiens
425 PCNA 5111
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
FRET Homo sapiens
Co-fractionation Homo sapiens
426 PDZD8 118987
Affinity Capture-MS Homo sapiens
427 UFL1 23376
Affinity Capture-MS Homo sapiens
428 DNM1L 10059
Affinity Capture-MS Homo sapiens
429 NFYB  
Co-fractionation Homo sapiens
430 USP35  
Affinity Capture-MS Homo sapiens
431 METTL3  
Affinity Capture-MS Homo sapiens
432 ERG  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
433 EID1  
Two-hybrid Homo sapiens
434 AR 367
Affinity Capture-Western Homo sapiens
435 RC3H1 149041
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
436 ATXN3 4287
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
437 SSRP1 6749
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
438 NOTCH1 4851
Two-hybrid Homo sapiens
439 HIST1H2AE 3012
Affinity Capture-MS Homo sapiens
440 EP300 2033
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
441 RPSA 3921
Co-fractionation Homo sapiens
442 RIT1 6016
Negative Genetic Homo sapiens
443 IGF2BP1 10642
Proximity Label-MS Homo sapiens
444 FMNL1 752
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
445 CCT3 7203
Two-hybrid Homo sapiens
Proximity Label-MS Homo sapiens
446 COIL  
Reconstituted Complex Homo sapiens
447 PAXIP1  
Affinity Capture-MS Homo sapiens
448 POT1  
Affinity Capture-MS Homo sapiens
449 PSMD6 9861
Affinity Capture-MS Homo sapiens
450 MSH6 2956
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
451 BCLAF1 9774
Proximity Label-MS Homo sapiens
452 PTBP1 5725
Proximity Label-MS Homo sapiens
453 TADA3  
Two-hybrid Homo sapiens
454 SSB 6741
Proximity Label-MS Homo sapiens
455 TNRC18  
Affinity Capture-MS Homo sapiens
456 NFYC 4802
Co-fractionation Homo sapiens
457 SUB1 10923
Co-fractionation Homo sapiens
458 CDK5RAP1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
459 CCT4 10575
Proximity Label-MS Homo sapiens
460 PPIA 5478
Proximity Label-MS Homo sapiens
461 DVL3 1857
Proximity Label-MS Homo sapiens
462 QRSL1  
Two-hybrid Homo sapiens
463 ANKRD28 23243
Affinity Capture-MS Homo sapiens
464 ILF2 3608
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
465 USP36  
Affinity Capture-MS Homo sapiens
466 KIAA1429 25962
Affinity Capture-MS Homo sapiens
467 EIF4ENIF1 56478
Two-hybrid Homo sapiens
468 TMOD3 29766
Co-fractionation Homo sapiens
469 TOP2A 7153
Affinity Capture-MS Homo sapiens
470 GSE1 23199
Two-hybrid Homo sapiens
471 COPS5 10987
Affinity Capture-MS Homo sapiens
472 ZNF512B  
Two-hybrid Homo sapiens
Proximity Label-MS Homo sapiens
473 PRIM1  
Co-fractionation Homo sapiens
474 PSMC6 5706
Affinity Capture-MS Homo sapiens
475 EED  
Affinity Capture-MS Homo sapiens
476 KMT2A  
Proximity Label-MS Homo sapiens
477 ARHGAP5 394
Co-fractionation Homo sapiens
478 HNRNPK 3190
Co-fractionation Homo sapiens
479 TERT  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
480 H2AFY2 55506
Proximity Label-MS Homo sapiens
481 MYCN  
Affinity Capture-MS Homo sapiens
482 RAD50 10111
Co-fractionation Homo sapiens
483 CHD3 1107
Proximity Label-MS Homo sapiens
484 OBSL1 23363
Affinity Capture-MS Homo sapiens
485 DVL2 1856
Proximity Label-MS Homo sapiens
486 TRIP12 9320
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
Proximity Label-MS Homo sapiens
487 TPT1 7178
Co-fractionation Homo sapiens
488 WRN 7486
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
489 INTS12  
Proximity Label-MS Homo sapiens
490 PDK1 5163
Two-hybrid Homo sapiens
491 COX15 1355
Affinity Capture-MS Homo sapiens
492 EMD 2010
Affinity Capture-MS Homo sapiens
493 PSMD4 5710
Affinity Capture-MS Homo sapiens
494 HSP90B1 7184
Proximity Label-MS Homo sapiens
495 NONO 4841
Co-fractionation Homo sapiens
496 NCAPD2 9918
Cross-Linking-MS (XL-MS) Homo sapiens
497 TKT 7086
Co-fractionation Homo sapiens
498 HTT 3064
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
499 RNF146  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
500 BZLF1  
Affinity Capture-MS
501 CD2BP2 10421
Proximity Label-MS Homo sapiens
502 PRDM16 63976
Proximity Label-MS Homo sapiens
503 SWAP70 23075
Co-fractionation Homo sapiens
504 VCP 7415
Affinity Capture-MS Homo sapiens
505 SMAD3 4088
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
506 CHEK1  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
507 SUMO2 6613
Reconstituted Complex Homo sapiens
508 RPL27A 6157
Proximity Label-MS Homo sapiens
509 CRY2  
Affinity Capture-MS Homo sapiens
510 GANAB 23193
Co-fractionation Homo sapiens
511 DNM2 1785
Affinity Capture-MS Homo sapiens
512 H2AFY 9555
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
513 CEBPA  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
514 PRKACB 5567
Affinity Capture-MS Homo sapiens
515 ATP5B 506
Proximity Label-MS Homo sapiens
516 HIST1H2AB 8335
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
517 ST13 6767
Co-fractionation Homo sapiens
518 PHB 5245
Proximity Label-MS Homo sapiens
519 NUMA1 4926
Proximity Label-MS Homo sapiens
520 SFPQ 6421
Co-fractionation Homo sapiens
521 HSF1  
Reconstituted Complex Homo sapiens
522 HIST1H3A 8350
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
523 FANCD2  
Affinity Capture-MS Homo sapiens
524 CUL3 8452
Affinity Capture-MS Homo sapiens
525 SRSF7 6432
Proximity Label-MS Homo sapiens
526 POLR2H 5437
Co-fractionation Homo sapiens
527 OTUD1 220213
Affinity Capture-MS Homo sapiens
528 CCT6A 908
Proximity Label-MS Homo sapiens
529 RLIM 51132
Affinity Capture-MS Homo sapiens
530 NAA15 80155
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
531 SAP30BP  
Proximity Label-MS Homo sapiens
532 HOXB7 3217
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
533 PDIA3 2923
Co-fractionation Homo sapiens
534 ADNP 23394
Proximity Label-MS Homo sapiens
535 PNRC2  
Two-hybrid Homo sapiens
536 TBCD 6904
Two-hybrid Homo sapiens
537 NXF1 10482
Affinity Capture-RNA Homo sapiens
538 AURKB 9212
Affinity Capture-MS Homo sapiens
539 ACADSB 36
Co-fractionation Homo sapiens
540 PIH1D1  
Proximity Label-MS Homo sapiens
541 HIST1H2BA 255626
Cross-Linking-MS (XL-MS) Homo sapiens
542 DNAJC9 23234
Proximity Label-MS Homo sapiens
543 RPAP3 79657
Proximity Label-MS Homo sapiens
544 BAZ1A 11177
Reconstituted Complex Homo sapiens
545 CHD8 57680
Proximity Label-MS Homo sapiens
546 VDAC1 7416
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
547 CLTC 1213
Two-hybrid Homo sapiens
Proximity Label-MS Homo sapiens
548 MDM2  
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
549 CCDC8  
Affinity Capture-MS Homo sapiens
550 ARAP1 116985
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
551 H2AFX 3014
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
552 VDAC3 7419
Proximity Label-MS Homo sapiens
553 ARRB2 409
Affinity Capture-MS Homo sapiens
554 VBP1 7411
Two-hybrid Homo sapiens
555 CLIC1 1192
Co-fractionation Homo sapiens
556 USP50  
Affinity Capture-MS Homo sapiens
557 KAT2A  
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
558 PAFAH1B3 5050
Two-hybrid Homo sapiens
559 SERPINA2  
Two-hybrid Homo sapiens
560 DNAJA2 10294
Proximity Label-MS Homo sapiens
561 PHRF1  
Affinity Capture-Western Homo sapiens
562 HSD17B4 3295
Co-fractionation Homo sapiens
563 ORC3  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
564 CUL5 8065
Affinity Capture-MS Homo sapiens
565 DGCR8  
Affinity Capture-MS Homo sapiens
566 SMURF1 57154
Affinity Capture-MS Homo sapiens
567 ELAVL1 1994
Proximity Label-MS Homo sapiens
568 CHD4 1108
Proximity Label-MS Homo sapiens
569 ELF3 1999
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
570 NUP50 10762
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
571 MOV10 4343
Affinity Capture-RNA Homo sapiens
572 H2AFZ 3015
Affinity Capture-MS Homo sapiens
Co-localization Homo sapiens
573 TRIP4 9325
Affinity Capture-MS Homo sapiens
574 RXRA 6256
Affinity Capture-MS Homo sapiens
575 TRIM31  
Affinity Capture-MS Homo sapiens
576 PINK1  
Affinity Capture-MS Homo sapiens
577 RPS6 6194
Proximity Label-MS Homo sapiens
578 XRCC6 2547
Biochemical Activity Homo sapiens
Proximity Label-MS Homo sapiens
Biochemical Activity Homo sapiens
Proximity Label-MS Homo sapiens
579 RARS 5917
Co-fractionation Homo sapiens
580 C9orf72  
Affinity Capture-MS Homo sapiens
581 USF1  
Affinity Capture-Western Homo sapiens
582 KIAA0408  
Two-hybrid Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here