Gene description for LIG3
Gene name	ligase III, DNA, ATP-dependent
Gene symbol	LIG3
Other names/aliases	LIG2
Species	Homo sapiens
Database cross references - LIG3
ExoCarta	ExoCarta_3980
Entrez Gene	3980
HGNC	6600
MIM	600940
UniProt	P49916
LIG3 identified in exosomes derived from the following tissue/cell type
Thymus	23844026

Gene ontology annotations for LIG3

Molecular Function     protein binding GO:0005515 IPI     zinc ion binding GO:0008270 IEA     DNA ligase activity GO:0003909 IDA     DNA binding GO:0003677 IEA     ATP binding GO:0005524 IEA     DNA ligase (ATP) activity GO:0003910 IMP Biological Process     negative regulation of mitochondrial DNA replication GO:0090298 IMP     double-strand break repair via alternative nonhomologous end joining GO:0097681 IGI     lagging strand elongation GO:0006273 IBA     mitochondrial DNA repair GO:0043504 IMP     double-strand break repair via nonhomologous end joining GO:0006303 IEA     base-excision repair GO:0006284 TAS     double-strand break repair GO:0006302 IDA     cell division GO:0051301 IEA     V(D)J recombination GO:0033151 IDA     mitochondrion organization GO:0007005 IDA     base-excision repair, DNA ligation GO:0006288 IMP     negative regulation of DNA recombination GO:0045910 IEA     cell cycle GO:0007049 IEA     DNA repair GO:0006281 TAS     DNA biosynthetic process GO:0071897 IEA     DNA ligation GO:0006266 IDA Subcellular Localization     cytoplasm GO:0005737 IBA     nucleus GO:0005634 IDA     nucleoplasm GO:0005654 TAS     mitochondrion GO:0005739 IEA     DNA ligase III-XRCC1 complex GO:0070421 IDA     synaptonemal complex GO:0000795 IEA