Gene description for PTPRH
Gene name protein tyrosine phosphatase, receptor type, H
Gene symbol PTPRH
Other names/aliases R-PTP-H
SAP1
Species Homo sapiens
 Database cross references - PTPRH
ExoCarta ExoCarta_5794
Vesiclepedia VP_5794
Entrez Gene 5794
HGNC 9672
MIM 602510
 PTPRH identified in exosomes derived from the following tissue/cell type
Pancreatic duct fluid 29339034    
Pancreatic duct fluid 29339034    
 Gene ontology annotations for PTPRH
Molecular Function
    protein binding GO:0005515 IPI
    transmembrane receptor protein tyrosine phosphatase activity GO:0005001 IEA
Biological Process
    protein dephosphorylation GO:0006470 TAS
    peptidyl-tyrosine dephosphorylation GO:0035335 TAS
    apoptotic process GO:0006915 IEA
Subcellular Localization
    cytoplasm GO:0005737 IEA
    integral component of plasma membrane GO:0005887 TAS
 Experiment description of studies that identified PTPRH in exosomes
1
Experiment ID 622
MISEV standards
EM
EV Biophysical techniques
EV Enriched markers
GOLGA2|CYC1
EV Negative markers
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 29339034    
Organism Homo sapiens
Experiment description Extracellular matrix proteins and carcinoembryonic antigen-related cell adhesion molecules characterize pancreatic duct fluid exosomes in patients with pancreatic cancer
Authors Zheng J, Hernandez JM, Doussot A, Bojmar L, Zambirinis CP, Costa-Silva B, van Beek EJAH, Mark MT, Molina H, Askan G, Basturk O, Gonen M, Kingham TP, Allen PJ, D'Angelica MI, DeMatteo RP, Lyden D, Jarnagin WR.
Journal name HPB
Publication year 2018
Sample Pancreatic duct fluid
Sample name From patients with Pancreatic ductal adenocarcinoma
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 623
MISEV standards
EV Biophysical techniques
EV Enriched markers
GOLGA2|CYC1
EV Negative markers
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 29339034    
Organism Homo sapiens
Experiment description Extracellular matrix proteins and carcinoembryonic antigen-related cell adhesion molecules characterize pancreatic duct fluid exosomes in patients with pancreatic cancer
Authors Zheng J, Hernandez JM, Doussot A, Bojmar L, Zambirinis CP, Costa-Silva B, van Beek EJAH, Mark MT, Molina H, Askan G, Basturk O, Gonen M, Kingham TP, Allen PJ, D'Angelica MI, DeMatteo RP, Lyden D, Jarnagin WR.
Journal name HPB
Publication year 2018
Sample Pancreatic duct fluid
Sample name From patients with IPMN with microinvasive cancer (IPMNca)
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PTPRH
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 MAPK1 5594
Invivo Homo sapiens
2 PTK2 5747
Invivo Homo sapiens
3 DOK1 1796
Invivo Homo sapiens
4 BCAR1 9564
Invivo Homo sapiens
Invitro Homo sapiens
5 PXN  
Invivo Homo sapiens
Invitro Homo sapiens
View the network image/svg+xml
 Pathways in which PTPRH is involved
No pathways found





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