Gene description for POLB
Gene name	polymerase (DNA directed), beta
Gene symbol	POLB
Other names/aliases	-
Species	Homo sapiens
Database cross references - POLB
ExoCarta	ExoCarta_5423
Vesiclepedia	VP_5423
Entrez Gene	5423
HGNC	9174
MIM	174760
UniProt	P06746
POLB identified in exosomes derived from the following tissue/cell type
Thymus	23844026

Gene ontology annotations for POLB

Molecular Function     damaged DNA binding GO:0003684 IEA     DNA-directed DNA polymerase activity GO:0003887 IBA     DNA-directed DNA polymerase activity GO:0003887 IDA     DNA-directed DNA polymerase activity GO:0003887 TAS     DNA-(apurinic or apyrimidinic site) endonuclease activity GO:0003906 TAS     protein binding GO:0005515 IPI     microtubule binding GO:0008017 IDA     lyase activity GO:0016829 IDA     enzyme binding GO:0019899 IPI     metal ion binding GO:0046872 IEA     5'-deoxyribose-5-phosphate lyase activity GO:0051575 IDA     class I DNA-(apurinic or apyrimidinic site) endonuclease activity GO:0140078 IDA Biological Process     in utero embryonic development GO:0001701 IEA     DNA-templated DNA replication GO:0006261 TAS     DNA repair GO:0006281 TAS     base-excision repair GO:0006284 IBA     base-excision repair GO:0006284 IDA     base-excision repair GO:0006284 IMP     base-excision repair GO:0006284 TAS     base-excision repair, gap-filling GO:0006287 TAS     pyrimidine dimer repair GO:0006290 IEA     nucleotide-excision repair, DNA gap filling GO:0006297 IMP     double-strand break repair via nonhomologous end joining GO:0006303 IBA     inflammatory response GO:0006954 IEA     DNA damage response GO:0006974 IMP     salivary gland morphogenesis GO:0007435 IEA     intrinsic apoptotic signaling pathway in response to DNA damage GO:0008630 IEA     response to gamma radiation GO:0010332 IEA     somatic hypermutation of immunoglobulin genes GO:0016446 IEA     response to ethanol GO:0045471 IEA     lymph node development GO:0048535 IEA     spleen development GO:0048536 IEA     homeostasis of number of cells GO:0048872 IEA     neuron apoptotic process GO:0051402 IEA     response to hyperoxia GO:0055093 IEA     immunoglobulin heavy chain V-D-J recombination GO:0071707 IEA     DNA biosynthetic process GO:0071897 IEA Subcellular Localization     nucleus GO:0005634 IBA     nucleus GO:0005634 IDA     nucleoplasm GO:0005654 TAS     cytoplasm GO:0005737 IDA     microtubule GO:0005874 IDA     spindle microtubule GO:0005876 IDA     protein-containing complex GO:0032991 IDA