Gene description for TOP1
Gene name topoisomerase (DNA) I
Gene symbol TOP1
Other names/aliases TOPI
Species Homo sapiens
 Database cross references - TOP1
ExoCarta ExoCarta_7150
Vesiclepedia VP_7150
Entrez Gene 7150
HGNC 11986
MIM 126420
UniProt P11387  
 TOP1 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 35918900    
Breast cancer cells 35918900    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Endothelial cells 26027894    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Monocytic leukemia cells 34108659    
Neuroblastoma cells 25944692    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Prostate cancer cells 25844599    
T lymphocytes 34108659    
Thymus 23844026    
 Gene ontology annotations for TOP1
Molecular Function
    RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 IDA
    DNA binding GO:0003677 EXP
    DNA binding GO:0003677 IDA
    DNA binding GO:0003677 IMP
    chromatin binding GO:0003682 IDA
    double-stranded DNA binding GO:0003690 IMP
    single-stranded DNA binding GO:0003697 IMP
    RNA binding GO:0003723 HDA
    DNA topoisomerase type I (single strand cut, ATP-independent) activity GO:0003917 IBA
    DNA topoisomerase type I (single strand cut, ATP-independent) activity GO:0003917 IDA
    DNA topoisomerase type I (single strand cut, ATP-independent) activity GO:0003917 IMP
    protein serine/threonine kinase activity GO:0004674 IMP
    protein binding GO:0005515 IPI
    ATP binding GO:0005524 IMP
    DNA binding, bending GO:0008301 EXP
    protein domain specific binding GO:0019904 IPI
    supercoiled DNA binding GO:0097100 IMP
Biological Process
    DNA replication GO:0006260 IBA
    DNA topological change GO:0006265 IBA
    DNA topological change GO:0006265 IDA
    DNA topological change GO:0006265 IMP
    chromatin remodeling GO:0006338 IMP
    chromosome segregation GO:0007059 IBA
    circadian rhythm GO:0007623 IEP
    response to xenobiotic stimulus GO:0009410 IEP
    programmed cell death GO:0012501 NAS
    phosphorylation GO:0016310 NAS
    peptidyl-serine phosphorylation GO:0018105 IMP
    circadian regulation of gene expression GO:0032922 IMP
    embryonic cleavage GO:0040016 IEA
Subcellular Localization
    nuclear chromosome GO:0000228 IDA
    P-body GO:0000932 IDA
    fibrillar center GO:0001650 IDA
    male germ cell nucleus GO:0001673 IEA
    nucleus GO:0005634 HDA
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 IDA
    nucleoplasm GO:0005654 IMP
    nucleoplasm GO:0005654 TAS
    nucleolus GO:0005730 IBA
    nucleolus GO:0005730 IDA
    nucleolus GO:0005730 IMP
    protein-DNA complex GO:0032993 IMP
    perikaryon GO:0043204 IEA
 Experiment description of studies that identified TOP1 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 1334
MISEV standards
Biophysical techniques
✔
CD9
Enriched markers
✔
ACTB
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35918900    
Organism Homo sapiens
Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL)
Authors "Bauzá-Martinez J, Armony G, Pronker MF, Wu W. "
Journal name J Extracell Vesicles
Publication year 2022
Sample Breast cancer cells
Sample name LM2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectometry
10
Experiment ID 1334
MISEV standards
Biophysical techniques
✔
CD9
Enriched markers
✔
ACTB
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35918900    
Organism Homo sapiens
Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL)
Authors "Bauzá-Martinez J, Armony G, Pronker MF, Wu W. "
Journal name J Extracell Vesicles
Publication year 2022
Sample Breast cancer cells
Sample name LM2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectometry
11
Experiment ID 1334
MISEV standards
Biophysical techniques
✔
CD9
Enriched markers
✔
ACTB
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35918900    
Organism Homo sapiens
Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL)
Authors "Bauzá-Martinez J, Armony G, Pronker MF, Wu W. "
Journal name J Extracell Vesicles
Publication year 2022
Sample Breast cancer cells
Sample name LM2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectometry
12
Experiment ID 1334
MISEV standards
Biophysical techniques
✔
CD9
Enriched markers
✔
ACTB
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35918900    
Organism Homo sapiens
Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL)
Authors "Bauzá-Martinez J, Armony G, Pronker MF, Wu W. "
Journal name J Extracell Vesicles
Publication year 2022
Sample Breast cancer cells
Sample name LM2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectometry
13
Experiment ID 1334
MISEV standards
Biophysical techniques
✔
CD9
Enriched markers
✔
ACTB
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35918900    
Organism Homo sapiens
Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL)
Authors "Bauzá-Martinez J, Armony G, Pronker MF, Wu W. "
Journal name J Extracell Vesicles
Publication year 2022
Sample Breast cancer cells
Sample name LM2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectometry
14
Experiment ID 1336
MISEV standards
Biophysical techniques
✔
CD9
Enriched markers
✔
ACTB
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35918900    
Organism Homo sapiens
Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL)
Authors "Bauzá-Martinez J, Armony G, Pronker MF, Wu W. "
Journal name J Extracell Vesicles
Publication year 2022
Sample Breast cancer cells
Sample name LM2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectometry
15
Experiment ID 1336
MISEV standards
Biophysical techniques
✔
CD9
Enriched markers
✔
ACTB
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35918900    
Organism Homo sapiens
Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL)
Authors "Bauzá-Martinez J, Armony G, Pronker MF, Wu W. "
Journal name J Extracell Vesicles
Publication year 2022
Sample Breast cancer cells
Sample name LM2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectometry
16
Experiment ID 1336
MISEV standards
Biophysical techniques
✔
CD9
Enriched markers
✔
ACTB
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35918900    
Organism Homo sapiens
Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL)
Authors "Bauzá-Martinez J, Armony G, Pronker MF, Wu W. "
Journal name J Extracell Vesicles
Publication year 2022
Sample Breast cancer cells
Sample name LM2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectometry
17
Experiment ID 1336
MISEV standards
Biophysical techniques
✔
CD9
Enriched markers
✔
ACTB
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35918900    
Organism Homo sapiens
Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL)
Authors "Bauzá-Martinez J, Armony G, Pronker MF, Wu W. "
Journal name J Extracell Vesicles
Publication year 2022
Sample Breast cancer cells
Sample name LM2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectometry
18
Experiment ID 1336
MISEV standards
Biophysical techniques
✔
CD9
Enriched markers
✔
ACTB
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35918900    
Organism Homo sapiens
Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL)
Authors "Bauzá-Martinez J, Armony G, Pronker MF, Wu W. "
Journal name J Extracell Vesicles
Publication year 2022
Sample Breast cancer cells
Sample name LM2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectometry
19
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
20
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
21
Experiment ID 282
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Ultracentrifugation - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
22
Experiment ID 283
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Ultracentrifugation - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
23
Experiment ID 285
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Sequential centrifugal ultrafiltration - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Sequential centrifugal ultrafiltration
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
24
Experiment ID 286
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Sequential centrifugal ultrafiltration - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Sequential centrifugal ultrafiltration
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
25
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
26
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
27
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
28
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
29
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
30
Experiment ID 226
MISEV standards
✔
EM
Biophysical techniques
✔
GAPDH|CD9|FLOT1
Enriched markers
✔
LMNA|H2AFX|ATP5A1|TOMM20
Negative markers
✘ Particle analysis
Identified molecule mRNA
Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
PubMed ID 26027894    
Organism Homo sapiens
Experiment description "Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting"
Authors "Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar"
Journal name Journal of Extracellular Vesicles
Publication year 2015
Sample Endothelial cells
Sample name HMEC-1
Isolation/purification methods Differential ultracentrifugation
Sucrose density gradient
Flotation density 1.10 g/mL
Molecules identified in the study miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA
Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting
31
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
32
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
33
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
34
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
35
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
36
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
37
Experiment ID 254
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name MNT-1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
38
Experiment ID 255
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name G1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
39
Experiment ID 256
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 501mel
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
40
Experiment ID 257
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name Daju
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
41
Experiment ID 259
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name A375M
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
42
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
43
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
44
Experiment ID 224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
45
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
46
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
47
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
48
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
49
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
50
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
51
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
52
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
53
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
54
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
55
Experiment ID 275
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel sensitive
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.12-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry/Flow cytometry/Western blotting
56
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
57
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for TOP1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 EIF3A 8661
Affinity Capture-MS Homo sapiens
2 RPA1 6117
Co-fractionation Homo sapiens
3 PQBP1  
Affinity Capture-MS Homo sapiens
4 PPP1CB 5500
Affinity Capture-MS Homo sapiens
5 RBL2 5934
Protein-peptide Homo sapiens
6 PCF11 51585
Affinity Capture-MS Homo sapiens
7 PRPF8 10594
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 LLGL1 3996
Synthetic Lethality Homo sapiens
9 TOP2B 7155
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
10 DDX21 9188
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 FAM208A  
Affinity Capture-MS Homo sapiens
12 DDX17 10521
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
13 BRCA1 672
Negative Genetic Homo sapiens
14 KIF20A 10112
Affinity Capture-MS Homo sapiens
15 BRD2  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
16 CSNK2A1 1457
Biochemical Activity Homo sapiens
17 SCAF4 57466
Affinity Capture-MS Homo sapiens
18 PRDM8  
Cross-Linking-MS (XL-MS) Homo sapiens
19 PRPF40A 55660
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
20 TAF15 8148
Affinity Capture-MS Homo sapiens
21 SOX2  
Proximity Label-MS Homo sapiens
22 CENPA  
Proximity Label-MS Homo sapiens
23 DDX23 9416
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
24 BTBD1  
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
25 WDR76  
Affinity Capture-MS Homo sapiens
26 RBM28 55131
Co-fractionation Homo sapiens
27 GTF2E2  
Affinity Capture-MS Homo sapiens
28 KIF23 9493
Affinity Capture-MS Homo sapiens
29 SF3B1 23451
Affinity Capture-MS Homo sapiens
Protein-peptide Homo sapiens
30 CIDEC  
Affinity Capture-MS Homo sapiens
31 CPSF7 79869
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
32 POU5F1  
Affinity Capture-MS Homo sapiens
33 FBL 2091
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
34 SPTY2D1  
Affinity Capture-MS Homo sapiens
35 POLR2C 5432
Affinity Capture-MS Homo sapiens
36 MECP2 4204
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
37 BUD31 8896
Affinity Capture-MS Homo sapiens
38 RPS11 6205
Synthetic Lethality Homo sapiens
39 MTA2 9219
Affinity Capture-MS Homo sapiens
40 RBM14 10432
Co-fractionation Homo sapiens
41 KIF14 9928
Affinity Capture-MS Homo sapiens
42 RBMX 27316
Affinity Capture-MS Homo sapiens
43 HEXIM1 10614
Affinity Capture-MS Homo sapiens
44 CHMP4C 92421
Affinity Capture-MS Homo sapiens
45 BRPF1  
Affinity Capture-MS Homo sapiens
46 TCOF1 6949
Affinity Capture-MS Homo sapiens
47 RFC5 5985
Affinity Capture-MS Homo sapiens
48 MEPCE 56257
Affinity Capture-MS Homo sapiens
49 TARBP2  
Protein-peptide Homo sapiens
50 SUPT5H 6829
Affinity Capture-MS Homo sapiens
51 CSTF2 1478
Affinity Capture-MS Homo sapiens
52 RBM4B  
Affinity Capture-MS Homo sapiens
53 RCL1 10171
Affinity Capture-MS Homo sapiens
54 HIST1H3E 8353
Affinity Capture-MS Homo sapiens
55 BRCA2 675
Synthetic Lethality Homo sapiens
56 CCNB1 891
Co-fractionation Homo sapiens
57 IWS1  
Affinity Capture-MS Homo sapiens
58 TTN 7273
Synthetic Lethality Homo sapiens
59 CKAP5 9793
Protein-peptide Homo sapiens
60 RPL31 6160
Proximity Label-MS Homo sapiens
61 SYNCRIP 10492
Affinity Capture-MS Homo sapiens
62 BANF1 8815
Affinity Capture-MS Homo sapiens
63 P4HB 5034
Affinity Capture-MS Homo sapiens
64 RFC4 5984
Affinity Capture-MS Homo sapiens
65 HECTD1 25831
Affinity Capture-MS Homo sapiens
66 RRP1B 23076
Affinity Capture-MS Homo sapiens
67 SON 6651
Affinity Capture-MS Homo sapiens
68 DDX39B 7919
Affinity Capture-MS Homo sapiens
69 SRPK1 6732
Affinity Capture-MS Homo sapiens
70 CCNT1  
Affinity Capture-MS Homo sapiens
71 SP100 6672
Affinity Capture-MS Homo sapiens
72 MGMT 4255
Affinity Capture-MS Homo sapiens
73 CD3EAP  
Proximity Label-MS Homo sapiens
74 SCARNA22  
Affinity Capture-RNA Homo sapiens
75 ANLN 54443
Affinity Capture-MS Homo sapiens
76 BRD7  
Affinity Capture-MS Homo sapiens
77 GTF3C3 9330
Co-fractionation Homo sapiens
78 RBM39 9584
Co-fractionation Homo sapiens
79 PPP2R2B 5521
Protein-peptide Homo sapiens
80 CSTF1 1477
Affinity Capture-MS Homo sapiens
81 SIRT7  
Affinity Capture-MS Homo sapiens
82 ESAM 90952
Affinity Capture-MS Homo sapiens
83 TAL1  
Affinity Capture-MS Homo sapiens
84 POLD3  
Co-fractionation Homo sapiens
85 CD274 29126
Affinity Capture-MS Homo sapiens
86 CUL3 8452
Affinity Capture-MS Homo sapiens
87 THOC7 80145
Affinity Capture-MS Homo sapiens
88 POLR2D  
Affinity Capture-MS Homo sapiens
89 ZC3H11A  
Affinity Capture-MS Homo sapiens
90 SLTM 79811
Affinity Capture-MS Homo sapiens
91 GTF3C4 9329
Co-fractionation Homo sapiens
92 YTHDC1  
Affinity Capture-MS Homo sapiens
93 GEMIN4 50628
Protein-peptide Homo sapiens
94 MFAP1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
95 RPA3 6119
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
96 ZMYND8 23613
Affinity Capture-MS Homo sapiens
97 FH 2271
Synthetic Lethality Homo sapiens
98 DLST 1743
Affinity Capture-MS Homo sapiens
99 SCAF11  
Affinity Capture-MS Homo sapiens
100 NDC80 10403
Affinity Capture-MS Homo sapiens
101 BIN3 55909
Affinity Capture-MS Homo sapiens
102 APLF  
Affinity Capture-MS Homo sapiens
103 HIST1H2AJ 8331
Affinity Capture-MS Homo sapiens
104 SUPT16H 11198
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
105 DDX55  
Cross-Linking-MS (XL-MS) Homo sapiens
106 PRKDC 5591
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
107 TNNT1  
Cross-Linking-MS (XL-MS) Homo sapiens
108 STUB1 10273
Co-fractionation Homo sapiens
109 NUDT21 11051
Affinity Capture-MS Homo sapiens
110 CHTOP  
Affinity Capture-MS Homo sapiens
111 CTR9 9646
Affinity Capture-MS Homo sapiens
112 BCAS2 10286
Affinity Capture-MS Homo sapiens
113 POLR2J  
Affinity Capture-MS Homo sapiens
114 CDK8 1024
Protein-peptide Homo sapiens
115 RBM25 58517
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
116 MTA1 9112
Affinity Capture-MS Homo sapiens
117 TCERG1 10915
Affinity Capture-MS Homo sapiens
118 SRSF9 8683
Affinity Capture-MS Homo sapiens
119 POLE3  
Co-fractionation Homo sapiens
120 CDC6  
Synthetic Lethality Homo sapiens
121 CDC40  
Affinity Capture-MS Homo sapiens
122 SUPT4H1  
Affinity Capture-MS Homo sapiens
123 TRA2B 6434
Affinity Capture-MS Homo sapiens
124 CPSF2 53981
Affinity Capture-MS Homo sapiens
125 PRPF31 26121
Affinity Capture-MS Homo sapiens
126 PWP1 11137
Co-fractionation Homo sapiens
127 IK 3550
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
128 NCL 4691
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
129 ALYREF 10189
Affinity Capture-MS Homo sapiens
130 HNRNPL 3191
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
131 SUPT6H 6830
Affinity Capture-MS Homo sapiens
132 SNRNP70 6625
Protein-peptide Homo sapiens
Affinity Capture-MS Homo sapiens
133 POLA1  
Co-fractionation Homo sapiens
134 INTS3 65123
Affinity Capture-MS Homo sapiens
135 PRPF4 9128
Affinity Capture-MS Homo sapiens
136 RPL23A 6147
Affinity Capture-MS Homo sapiens
137 CRNKL1 51340
Affinity Capture-MS Homo sapiens
138 CHAMP1  
Affinity Capture-MS Homo sapiens
139 SNRPA1 6627
Affinity Capture-MS Homo sapiens
140 POLD2 5425
Co-fractionation Homo sapiens
141 ROR1 4919
Negative Genetic Homo sapiens
142 CCAR1 55749
Affinity Capture-MS Homo sapiens
143 PDHA1 5160
Affinity Capture-MS Homo sapiens
144 LIG4 3981
Protein-peptide Homo sapiens
145 MCM3 4172
Affinity Capture-MS Homo sapiens
146 SMARCB1 6598
Affinity Capture-MS Homo sapiens
147 NCBP1 4686
Affinity Capture-MS Homo sapiens
148 GTF3C5 9328
Co-fractionation Homo sapiens
149 RBM22 55696
Affinity Capture-MS Homo sapiens
150 EIF3K 27335
Affinity Capture-MS Homo sapiens
151 EXO1  
Affinity Capture-MS Homo sapiens
152 PPIL4  
Affinity Capture-MS Homo sapiens
153 TARDBP 23435
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
154 BTF3 689
Affinity Capture-MS Homo sapiens
155 HIST1H2BG 8339
Proximity Label-MS Homo sapiens
156 THRAP3 9967
Affinity Capture-MS Homo sapiens
157 USP39 10713
Affinity Capture-MS Homo sapiens
158 NOP56 10528
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
159 ARL6IP4  
Affinity Capture-MS Homo sapiens
160 ZNF638 27332
Affinity Capture-MS Homo sapiens
161 ZFR 51663
Affinity Capture-MS Homo sapiens
162 ATM 472
Protein-peptide Homo sapiens
163 CAND1 55832
Affinity Capture-MS Homo sapiens
164 FSHR  
Two-hybrid Homo sapiens
165 SNRPF 6636
Affinity Capture-MS Homo sapiens
166 SAFB 6294
Affinity Capture-MS Homo sapiens
167 CHRAC1  
Affinity Capture-MS Homo sapiens
168 XRCC1 7515
Affinity Capture-MS Homo sapiens
169 PPP2R1B 5519
Affinity Capture-MS Homo sapiens
170 RNPS1 10921
Affinity Capture-MS Homo sapiens
171 SUV420H2  
Affinity Capture-MS Homo sapiens
172 APAF1 317
Protein-peptide Homo sapiens
173 H1FX 8971
Affinity Capture-MS Homo sapiens
174 MPHOSPH8 54737
Affinity Capture-MS Homo sapiens
175 PRC1 9055
Affinity Capture-MS Homo sapiens
176 MAGOHB 55110
Affinity Capture-MS Homo sapiens
177 NPM1 4869
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
178 SRRM2 23524
Affinity Capture-MS Homo sapiens
179 KHDRBS1 10657
Affinity Capture-MS Homo sapiens
180 OBSL1 23363
Affinity Capture-MS Homo sapiens
181 GRWD1 83743
Protein-peptide Homo sapiens
182 VCAM1 7412
Affinity Capture-MS Homo sapiens
183 CUL1 8454
Affinity Capture-MS Homo sapiens
184 HNRNPD 3184
Affinity Capture-MS Homo sapiens
185 PES1 23481
Affinity Capture-MS Homo sapiens
186 LSM2 57819
Affinity Capture-MS Homo sapiens
187 PHF10  
Affinity Capture-MS Homo sapiens
188 JMJD6 23210
Affinity Capture-MS Homo sapiens
189 SYMPK 8189
Protein-peptide Homo sapiens
Affinity Capture-MS Homo sapiens
190 HIST2H2AB 317772
Affinity Capture-MS Homo sapiens
191 HNRNPA0 10949
Affinity Capture-MS Homo sapiens
192 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
193 TRIM26 7726
Affinity Capture-MS Homo sapiens
194 WHSC1 7468
Proximity Label-MS Homo sapiens
195 TRA2A 29896
Affinity Capture-MS Homo sapiens
196 PSMD14 10213
Affinity Capture-MS Homo sapiens
197 ACIN1 22985
Affinity Capture-MS Homo sapiens
198 POLA2  
Co-fractionation Homo sapiens
199 TRIM24  
Affinity Capture-MS Homo sapiens
200 SNRNP200 23020
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
201 CFDP1  
Affinity Capture-MS Homo sapiens
202 TSPYL5  
Affinity Capture-MS Homo sapiens
203 CCDC12  
Affinity Capture-MS Homo sapiens
204 SNRPD1 6632
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
205 CSTF3 1479
Affinity Capture-MS Homo sapiens
206 PLRG1 5356
Affinity Capture-MS Homo sapiens
207 RAD18  
Affinity Capture-MS Homo sapiens
208 TOX4  
Affinity Capture-MS Homo sapiens
209 GTF3C1  
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
210 MAGOH 4116
Affinity Capture-MS Homo sapiens
211 POLB 5423
Affinity Capture-MS Homo sapiens
212 TXNL4A 10907
Affinity Capture-MS Homo sapiens
213 CDK4 1019
Negative Genetic Homo sapiens
214 ZCCHC8 55596
Affinity Capture-MS Homo sapiens
215 FGFBP1 9982
Affinity Capture-MS Homo sapiens
216 ATG16L1 55054
Affinity Capture-MS Homo sapiens
217 RECQL5  
Affinity Capture-MS Homo sapiens
218 FAM76B  
Affinity Capture-MS Homo sapiens
219 LEO1 123169
Affinity Capture-MS Homo sapiens
220 POP1 10940
Affinity Capture-MS Homo sapiens
221 TPR 7175
Co-fractionation Homo sapiens
222 IKZF3  
Affinity Capture-MS Homo sapiens
223 POLR2E 5434
Affinity Capture-MS Homo sapiens
224 WDR33 55339
Affinity Capture-MS Homo sapiens
225 SETD2  
Affinity Capture-MS Homo sapiens
226 YLPM1 56252
Affinity Capture-MS Homo sapiens
227 EGFR 1956
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
228 METTL3  
Affinity Capture-MS Homo sapiens
229 IKZF1  
Affinity Capture-MS Homo sapiens
230 ZMAT2  
Affinity Capture-MS Homo sapiens
231 WEE1 7465
Synthetic Lethality Homo sapiens
232 EFTUD2 9343
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
233 CDK2 1017
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
234 MYC  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
235 HMGB3 3149
Co-fractionation Homo sapiens
236 NLRP3  
Affinity Capture-MS Homo sapiens
237 TERF2  
Affinity Capture-MS Homo sapiens
238 CSNK2A2 1459
Biochemical Activity Homo sapiens
239 NIPBL 25836
Affinity Capture-MS Homo sapiens
240 RAI1 10743
Affinity Capture-MS Homo sapiens
241 HNRNPAB 3182
Affinity Capture-MS Homo sapiens
242 SNW1 22938
Protein-peptide Homo sapiens
Affinity Capture-MS Homo sapiens
243 DDRGK1 65992
Affinity Capture-MS Homo sapiens
244 TERF2IP 54386
Affinity Capture-MS Homo sapiens
245 NFYA 4800
Co-fractionation Homo sapiens
246 HMG20A  
Affinity Capture-MS Homo sapiens
247 ADAR 103
Affinity Capture-MS Homo sapiens
248 OAS3 4940
Affinity Capture-MS Homo sapiens
249 EIF3H 8667
Affinity Capture-MS Homo sapiens
250 PA2G4 5036
Affinity Capture-MS Homo sapiens
251 PRICKLE3  
Affinity Capture-MS Homo sapiens
252 C17orf80 55028
Affinity Capture-MS Homo sapiens
253 RSF1  
Affinity Capture-MS Homo sapiens
254 PARP1 142
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
255 HDGF 3068
Affinity Capture-MS Homo sapiens
256 H3F3A 3020
Affinity Capture-MS Homo sapiens
257 TP53 7157
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
258 FOLR1 2348
Affinity Capture-MS Homo sapiens
259 PHF3  
Affinity Capture-MS Homo sapiens
260 C1orf35  
Affinity Capture-MS Homo sapiens
261 TSC1 7248
Negative Genetic Homo sapiens
262 BUB3 9184
Protein-peptide Homo sapiens
263 HNRNPK 3190
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
264 ESR1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
265 DDX39A 10212
Affinity Capture-MS Homo sapiens
266 EIF3J 8669
Affinity Capture-MS Homo sapiens
267 TUBD1  
Protein-peptide Homo sapiens
268 DDX42 11325
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
269 TOPORS  
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
270 PRMT1 3276
Affinity Capture-MS Homo sapiens
271 AK1 203
Cross-Linking-MS (XL-MS) Homo sapiens
272 JAK1 3716
Protein-peptide Homo sapiens
273 RALY 22913
Affinity Capture-MS Homo sapiens
274 SCAF1  
Affinity Capture-MS Homo sapiens
275 MCM7 4176
Affinity Capture-MS Homo sapiens
276 UBE2H 7328
Affinity Capture-MS Homo sapiens
277 HNRNPC 3183
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
278 TMEM14B  
Affinity Capture-MS Homo sapiens
279 GATAD2B 57459
Affinity Capture-MS Homo sapiens
280 SNRPG 6637
Affinity Capture-MS Homo sapiens
281 RCVRN  
Protein-peptide Homo sapiens
282 PMS1  
Affinity Capture-Western Homo sapiens
283 ZNF326 284695
Affinity Capture-MS Homo sapiens
284 RPS19 6223
Affinity Capture-MS Homo sapiens
285 CDC26 246184
Affinity Capture-MS Homo sapiens
286 HNRNPR 10236
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
287 PPP1R10  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
288 HNRNPUL2 221092
Affinity Capture-MS Homo sapiens
289 INTS8  
Affinity Capture-MS Homo sapiens
290 CUL7 9820
Affinity Capture-MS Homo sapiens
291 CDC16 8881
Affinity Capture-MS Homo sapiens
292 MCM2 4171
Affinity Capture-MS Homo sapiens
293 SMARCA1 6594
Affinity Capture-MS Homo sapiens
294 LIG1 3978
Co-fractionation Homo sapiens
295 MCM6 4175
Affinity Capture-MS Homo sapiens
296 SNRNP48  
Cross-Linking-MS (XL-MS) Homo sapiens
297 ARID1A 8289
Negative Genetic Homo sapiens
Affinity Capture-MS Homo sapiens
298 HMGA2 8091
Co-fractionation Homo sapiens
299 ITGA4 3676
Affinity Capture-MS Homo sapiens
300 UTP20 27340
Co-fractionation Homo sapiens
301 PALB2  
Synthetic Lethality Homo sapiens
302 THOC1 9984
Affinity Capture-MS Homo sapiens
303 NCSTN 23385
Co-fractionation Homo sapiens
304 RBM8A 9939
Affinity Capture-MS Homo sapiens
305 FEN1 2237
Affinity Capture-MS Homo sapiens
306 POLR2K  
Affinity Capture-MS Homo sapiens
307 NF2 4771
Affinity Capture-MS Homo sapiens
308 EIF2AK2 5610
Affinity Capture-MS Homo sapiens
309 SRRT 51593
Affinity Capture-MS Homo sapiens
310 P4HA1 5033
Affinity Capture-MS Homo sapiens
311 PPIH 10465
Affinity Capture-MS Homo sapiens
312 SRRM1 10250
Affinity Capture-MS Homo sapiens
313 PARK2  
Affinity Capture-MS Homo sapiens
314 PPIL1 51645
Affinity Capture-MS Homo sapiens
315 PHF14 9678
Affinity Capture-MS Homo sapiens
316 NOP2 4839
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
317 CBX3 11335
Proximity Label-MS Homo sapiens
318 WDR61 80349
Affinity Capture-MS Homo sapiens
319 CHMP4B 128866
Affinity Capture-MS Homo sapiens
320 RPA2 6118
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
321 BARD1 580
Protein-peptide Homo sapiens
322 NTRK1 4914
Affinity Capture-MS Homo sapiens
323 U2AF2 11338
Protein-peptide Homo sapiens
324 NSRP1  
Affinity Capture-MS Homo sapiens
325 DHX9 1660
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
326 SUB1 10923
Co-fractionation Homo sapiens
327 SAFB2 9667
Affinity Capture-MS Homo sapiens
328 HNRNPA3 220988
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
329 HDAC5 10014
Affinity Capture-MS Homo sapiens
330 RBM10  
Affinity Capture-MS Homo sapiens
331 POLR2B 5431
Affinity Capture-MS Homo sapiens
332 LARP1 23367
Affinity Capture-MS Homo sapiens
333 RBL1  
Protein-peptide Homo sapiens
334 DHX8 1659
Affinity Capture-MS Homo sapiens
335 HNRNPDL 9987
Affinity Capture-MS Homo sapiens
336 RBBP6 5930
Affinity Capture-MS Homo sapiens
337 DPF2  
Affinity Capture-MS Homo sapiens
338 ZBTB2 57621
Affinity Capture-MS Homo sapiens
339 CCNA2 890
Co-fractionation Homo sapiens
340 KMT2A  
Protein-peptide Homo sapiens
Affinity Capture-MS Homo sapiens
341 CDC73  
Synthetic Lethality Homo sapiens
Affinity Capture-MS Homo sapiens
342 MSH2 4436
Synthetic Lethality Homo sapiens
343 BAZ1B 9031
Affinity Capture-MS Homo sapiens
344 SMARCA5 8467
Affinity Capture-MS Homo sapiens
345 ELK3  
Protein-peptide Homo sapiens
346 PDGFRA 5156
Negative Genetic Homo sapiens
347 RPRD2  
Affinity Capture-MS Homo sapiens
348 NR3C1 2908
Proximity Label-MS Homo sapiens
349 DCAF13 25879
Affinity Capture-MS Homo sapiens
350 DDB2  
Protein-peptide Homo sapiens
351 GTF3C2  
Co-fractionation Homo sapiens
352 YY1 7528
Affinity Capture-MS Homo sapiens
353 FNTA 2339
Negative Genetic Homo sapiens
354 POLR2A 5430
Affinity Capture-MS Homo sapiens
355 RFC1 5981
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
356 NCBP2 22916
Affinity Capture-MS Homo sapiens
357 SOX15  
Affinity Capture-MS Homo sapiens
358 MAU2  
Affinity Capture-MS Homo sapiens
359 PRPF19 27339
Affinity Capture-MS Homo sapiens
360 PSPC1 55269
Affinity Capture-MS Homo sapiens
361 PPWD1 23398
Affinity Capture-MS Homo sapiens
362 ZC3H18  
Affinity Capture-MS Homo sapiens
363 HIST1H1C 3006
Affinity Capture-MS Homo sapiens
364 MTOR 2475
Negative Genetic Homo sapiens
365 RPS14 6208
Co-fractionation Homo sapiens
366 NHP2L1 4809
Affinity Capture-MS Homo sapiens
367 HP1BP3 50809
Affinity Capture-MS Homo sapiens
368 SKIV2L2 23517
Affinity Capture-MS Homo sapiens
369 MATR3 9782
Affinity Capture-MS Homo sapiens
370 DIDO1  
Affinity Capture-MS Homo sapiens
371 RNF2  
Affinity Capture-MS Homo sapiens
372 RBBP5 5929
Affinity Capture-MS Homo sapiens
373 TSR1 55720
Affinity Capture-MS Homo sapiens
374 ILF3 3609
Affinity Capture-MS Homo sapiens
375 XRCC5 7520
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
376 CBX4  
Affinity Capture-MS Homo sapiens
377 DHX16 8449
Affinity Capture-MS Homo sapiens
378 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
379 DUS4L  
Affinity Capture-MS Homo sapiens
380 MAX  
Co-fractionation Homo sapiens
381 LIG3 3980
Affinity Capture-MS Homo sapiens
382 JUP 3728
Co-fractionation Homo sapiens
383 FBXL6  
Affinity Capture-MS Homo sapiens
384 ICT1 3396
Affinity Capture-MS Homo sapiens
385 MCM5 4174
Affinity Capture-MS Homo sapiens
386 PPP1CC 5501
Affinity Capture-MS Homo sapiens
387 MAGEB2 4113
Affinity Capture-MS Homo sapiens
388 MEN1 4221
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
389 SNRPA 6626
Affinity Capture-MS Homo sapiens
390 HNRNPM 4670
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
391 PBRM1 55193
Negative Genetic Homo sapiens
Affinity Capture-MS Homo sapiens
392 SHFM1 7979
Affinity Capture-MS Homo sapiens
393 RBM15 64783
Affinity Capture-MS Homo sapiens
394 S100A9 6280
Co-fractionation Homo sapiens
395 MKI67  
Affinity Capture-MS Homo sapiens
396 PCNA 5111
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
397 UFL1 23376
Affinity Capture-MS Homo sapiens
398 NF1 4763
Synthetic Lethality Homo sapiens
399 PYGM 5837
Protein-peptide Homo sapiens
400 NFYB  
Co-fractionation Homo sapiens
401 SRCAP  
Affinity Capture-MS Homo sapiens
402 EAF1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
403 TCF20  
Affinity Capture-MS Homo sapiens
404 LAMB3 3914
Affinity Capture-MS Homo sapiens
405 RPRD1B 58490
Affinity Capture-MS Homo sapiens
406 ERG  
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
407 RC3H1 149041
Affinity Capture-MS Homo sapiens
408 SSRP1 6749
Affinity Capture-MS Homo sapiens
409 POGZ 23126
Affinity Capture-MS Homo sapiens
410 DDX56  
Affinity Capture-MS Homo sapiens
411 CDKN2A 1029
Affinity Capture-Western Homo sapiens
412 RPSA 3921
Affinity Capture-MS Homo sapiens
413 POLR2G 5436
Affinity Capture-MS Homo sapiens
414 PRIM2 5558
Co-fractionation Homo sapiens
415 IGF2BP1 10642
Affinity Capture-MS Homo sapiens
416 IRF4  
Protein-peptide Homo sapiens
417 COIL  
Proximity Label-MS Homo sapiens
418 MSH6 2956
Affinity Capture-MS Homo sapiens
419 BCLAF1 9774
Affinity Capture-MS Homo sapiens
420 PPIE 10450
Affinity Capture-MS Homo sapiens
421 LHX2  
Proximity Label-MS Homo sapiens
422 NFYC 4802
Co-fractionation Homo sapiens
423 ZC3H14  
Affinity Capture-MS Homo sapiens
424 CTNNBL1 56259
Affinity Capture-MS Homo sapiens
425 RBM6 10180
Affinity Capture-MS Homo sapiens
426 LSM4 25804
Protein-peptide Homo sapiens
Affinity Capture-MS Homo sapiens
427 PRPSAP2 5636
Affinity Capture-MS Homo sapiens
428 ZC3H4 23211
Affinity Capture-MS Homo sapiens
429 PRPF3  
Affinity Capture-MS Homo sapiens
430 BUD13  
Affinity Capture-MS Homo sapiens
431 SNRPD2 6633
Affinity Capture-MS Homo sapiens
432 APP 351
Reconstituted Complex Homo sapiens
433 PDE10A 10846
Protein-peptide Homo sapiens
434 ILF2 3608
Affinity Capture-MS Homo sapiens
435 USP36  
Affinity Capture-MS Homo sapiens
436 KIAA1429 25962
Affinity Capture-MS Homo sapiens
437 TOP2A 7153
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
438 CDK14 5218
Affinity Capture-MS Homo sapiens
439 ATXN2L 11273
Affinity Capture-MS Homo sapiens
440 INIP  
Affinity Capture-MS Homo sapiens
441 ISY1 57461
Affinity Capture-MS Homo sapiens
442 EIF4A3 9775
Affinity Capture-MS Homo sapiens
443 ARID4B  
Affinity Capture-MS Homo sapiens
444 COPS5 10987
Affinity Capture-MS Homo sapiens
445 FBXW7  
Affinity Capture-MS Homo sapiens
446 NCOA5  
Affinity Capture-MS Homo sapiens
447 WTAP 9589
Affinity Capture-MS Homo sapiens
448 SNRPC 6631
Affinity Capture-MS Homo sapiens
449 PRIM1  
Co-fractionation Homo sapiens
450 INTS12  
Affinity Capture-MS Homo sapiens
451 EED  
Affinity Capture-MS Homo sapiens
452 INTS6 26512
Affinity Capture-MS Homo sapiens
453 CDT1  
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
454 PPP1R8 5511
Affinity Capture-MS Homo sapiens
455 CDK1 983
Co-fractionation Homo sapiens
456 H2AFY2 55506
Affinity Capture-MS Homo sapiens
457 MYCN  
Affinity Capture-MS Homo sapiens
458 ERBB2 2064
Negative Genetic Homo sapiens
459 CPNE3 8895
Cross-Linking-MS (XL-MS) Homo sapiens
460 RPS26 6231
Affinity Capture-MS Homo sapiens
461 H2AFZ 3015
Affinity Capture-MS Homo sapiens
462 PRPF6 24148
Affinity Capture-MS Homo sapiens
463 PPP1CA 5499
Affinity Capture-MS Homo sapiens
464 POLD1 5424
Co-fractionation Homo sapiens
465 COX15 1355
Affinity Capture-MS Homo sapiens
466 ECT2 1894
Affinity Capture-MS Homo sapiens
467 SNRNP40 9410
Affinity Capture-MS Homo sapiens
468 NONO 4841
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
469 STAU1 6780
Affinity Capture-MS Homo sapiens
470 PRPS2 5634
Affinity Capture-MS Homo sapiens
471 UBE2I 7329
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
472 PRB1  
Protein-peptide Homo sapiens
473 SMARCA4 6597
Affinity Capture-MS Homo sapiens
474 VCP 7415
Affinity Capture-MS Homo sapiens
475 DDX5 1655
Affinity Capture-MS Homo sapiens
476 ACTL6A 86
Affinity Capture-MS Homo sapiens
477 IFI16 3428
Affinity Capture-MS Homo sapiens
478 CHEK1  
Synthetic Lethality Homo sapiens
479 TRIM32 22954
Protein-peptide Homo sapiens
480 SF3B6 51639
Co-fractionation Homo sapiens
481 PABPN1 8106
Affinity Capture-MS Homo sapiens
482 POLE  
Co-fractionation Homo sapiens
483 BRD4 23476
Affinity Capture-MS Homo sapiens
484 H2AFY 9555
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
485 CEBPA  
Protein-peptide Homo sapiens
486 PRKACB 5567
Affinity Capture-MS Homo sapiens
487 SMARCC2 6601
Affinity Capture-MS Homo sapiens
488 WDR82 80335
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
489 SRSF11 9295
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
490 SFPQ 6421
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
491 CPSF1 29894
Affinity Capture-MS Homo sapiens
492 IRF9 10379
Protein-peptide Homo sapiens
493 PRPF4B 8899
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
494 HIST1H3A 8350
Proximity Label-MS Homo sapiens
495 FANCD2  
Affinity Capture-MS Homo sapiens
496 TRIM31  
Affinity Capture-MS Homo sapiens
497 POLR2H 5437
Co-fractionation Homo sapiens
498 PNN 5411
Affinity Capture-MS Homo sapiens
499 SNRPB 6628
Cross-Linking-MS (XL-MS) Homo sapiens
500 NAT10 55226
Affinity Capture-MS Homo sapiens
501 CTNNB1 1499
Co-fractionation Homo sapiens
502 SRSF1 6426
Affinity Capture-Western Homo sapiens
Far Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
503 HCFC1 3054
Affinity Capture-MS Homo sapiens
504 ERCC8  
Protein-peptide Homo sapiens
505 XAB2 56949
Affinity Capture-MS Homo sapiens
506 CTTN 2017
Affinity Capture-MS Homo sapiens
507 ADNP 23394
Affinity Capture-MS Homo sapiens
508 THOC5 8563
Affinity Capture-MS Homo sapiens
509 NKX3-1  
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
510 MCM4 4173
Affinity Capture-MS Homo sapiens
511 EP400  
Affinity Capture-MS Homo sapiens
512 CBX2  
Affinity Capture-MS Homo sapiens
513 SUZ12  
Affinity Capture-MS Homo sapiens
514 SART1 9092
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
515 AKAP8  
Affinity Capture-MS Homo sapiens
516 IL7R  
Protein-RNA Homo sapiens
517 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
518 IRF8  
Protein-peptide Homo sapiens
519 MAP3K4 4216
Synthetic Lethality Homo sapiens
520 FIP1L1 81608
Affinity Capture-MS Homo sapiens
521 BAZ1A 11177
Cross-Linking-MS (XL-MS) Homo sapiens
522 SF3B3 23450
Affinity Capture-MS Homo sapiens
523 VDAC1 7416
Affinity Capture-MS Homo sapiens
524 EIF4A2 1974
Co-fractionation Homo sapiens
525 BMP4 652
Affinity Capture-MS Homo sapiens
526 BRD3 8019
Affinity Capture-MS Homo sapiens
527 MDM2  
Affinity Capture-MS Homo sapiens
528 RBBP4 5928
Affinity Capture-MS Homo sapiens
529 INTS9 55756
Affinity Capture-MS Homo sapiens
530 PAF1 54623
Affinity Capture-MS Homo sapiens
531 ZRANB2 9406
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
532 CPSF6 11052
Affinity Capture-MS Homo sapiens
533 RAD17  
Synthetic Lethality Homo sapiens
534 ERH 2079
Affinity Capture-MS Homo sapiens
535 SMARCC1 6599
Affinity Capture-MS Homo sapiens
536 PPHLN1  
Affinity Capture-MS Homo sapiens
537 NUFIP2 57532
Affinity Capture-MS Homo sapiens
538 SAP18 10284
Affinity Capture-MS Homo sapiens
539 DPY30 84661
Affinity Capture-MS Homo sapiens
540 HNRNPA2B1 3181
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
541 INTS2  
Affinity Capture-MS Homo sapiens
542 ELAVL1 1994
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
543 CHD4 1108
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
544 TAF2  
Affinity Capture-MS Homo sapiens
545 CWC15  
Affinity Capture-MS Homo sapiens
546 BTBD2  
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
547 LRPAP1 4043
Affinity Capture-MS Homo sapiens
548 FAM161A  
Cross-Linking-MS (XL-MS) Homo sapiens
549 CDK9 1025
Affinity Capture-MS Homo sapiens
550 CBX8 57332
Affinity Capture-MS Homo sapiens
551 RPS6 6194
Proximity Label-MS Homo sapiens
552 GEMIN5 25929
Affinity Capture-MS Homo sapiens
553 GRSF1 2926
Proximity Label-MS Homo sapiens
554 XRCC6 2547
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
555 LSM6 11157
Affinity Capture-MS Homo sapiens
556 EIF5A 1984
Affinity Capture-MS Homo sapiens
557 HNRNPU 3192
Affinity Capture-MS Homo sapiens
558 METTL17  
Affinity Capture-MS Homo sapiens
559 TOP1MT  
Affinity Capture-MS Homo sapiens
560 CDC5L 988
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
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Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here