Gene description for BAZ1B
Gene name bromodomain adjacent to zinc finger domain, 1B
Gene symbol BAZ1B
Other names/aliases WBSCR10
WBSCR9
WSTF
Species Homo sapiens
 Database cross references - BAZ1B
ExoCarta ExoCarta_9031
Vesiclepedia VP_9031
Entrez Gene 9031
HGNC 961
MIM 605681
UniProt Q9UIG0  
 BAZ1B identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Urine 19056867    
 Gene ontology annotations for BAZ1B
Molecular Function
    non-membrane spanning protein tyrosine kinase activity GO:0004715 IEA
    protein binding GO:0005515 IPI
    ATP binding GO:0005524 IEA
    zinc ion binding GO:0008270 NAS
    histone kinase activity GO:0035173 IBA
    histone H3Y41 kinase activity GO:0035401 IEA
    histone binding GO:0042393 IBA
    histone H2AXY142 kinase activity GO:0140801 IDA
Biological Process
    chromatin remodeling GO:0006338 IBA
    chromatin remodeling GO:0006338 IMP
    chromatin remodeling GO:0006338 ISO
    chromatin remodeling GO:0006338 NAS
    chromatin remodeling GO:0006338 TAS
    regulation of transcription by RNA polymerase II GO:0006357 NAS
    DNA damage response GO:0006974 IBA
    DNA damage response GO:0006974 IDA
    DNA damage response GO:0006974 NAS
    post-translational protein modification GO:0043687 IDA
    positive regulation of transcription by RNA polymerase I GO:0045943 NAS
    positive regulation of transcription by RNA polymerase II GO:0045944 NAS
    positive regulation of transcription by RNA polymerase III GO:0045945 IDA
    negative regulation of mitotic chromosome condensation GO:1905213 IDA
    negative regulation of mitotic chromosome condensation GO:1905213 IMP
Subcellular Localization
    condensed chromosome GO:0000793 IEA
    nucleus GO:0005634 IDA
    nucleus GO:0005634 ISO
    nucleoplasm GO:0005654 IDA
    nucleoplasm GO:0005654 TAS
    pericentric heterochromatin GO:0005721 ISO
    nucleolus GO:0005730 NAS
    nuclear replication fork GO:0043596 IDA
    WICH complex GO:0090535 IBA
    WICH complex GO:0090535 IDA
    B-WICH complex GO:0110016 IDA
 Experiment description of studies that identified BAZ1B in exosomes
1
Experiment ID 489
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 63
MISEV standards
Biophysical techniques
AQP2
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for BAZ1B
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HIST2H2BE 8349
Affinity Capture-MS Homo sapiens
2 ZNF346  
Affinity Capture-MS Homo sapiens
3 KPNA1 3836
Affinity Capture-MS Homo sapiens
4 KLF9 687
Proximity Label-MS Homo sapiens
5 TOP2B 7155
Co-fractionation Homo sapiens
6 LHX2  
Proximity Label-MS Homo sapiens
7 MRPS10 55173
Affinity Capture-MS Homo sapiens
8 HIST1H2BG 8339
Proximity Label-MS Homo sapiens
9 ALPL 249
Affinity Capture-MS Homo sapiens
10 RPS19 6223
Affinity Capture-MS Homo sapiens
11 RPL10 6134
Affinity Capture-MS Homo sapiens
12 KIF20A 10112
Affinity Capture-MS Homo sapiens
13 BRD2  
Affinity Capture-MS Homo sapiens
14 SMARCD2 6603
Co-fractionation Homo sapiens
15 SOX2  
Proximity Label-MS Homo sapiens
16 CENPA  
Proximity Label-MS Homo sapiens
17 ANKRD50 57182
Affinity Capture-MS Homo sapiens
18 APEX1 328
Proximity Label-MS Homo sapiens
19 TOP2A 7153
Affinity Capture-MS Homo sapiens
20 ING3  
Affinity Capture-MS Homo sapiens
21 PRC1 9055
Affinity Capture-MS Homo sapiens
22 KLF8  
Proximity Label-MS Homo sapiens
23 LOC100506753  
Protein-RNA Homo sapiens
24 SF3B1 23451
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
25 SMARCA1 6594
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
26 FBXW7  
Affinity Capture-MS Homo sapiens
27 RPS10 6204
Affinity Capture-MS Homo sapiens
28 NPM1 4869
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
29 SRRM2 23524
Co-fractionation Homo sapiens
30 ATAD5  
Affinity Capture-MS Homo sapiens
31 OBSL1 23363
Affinity Capture-MS Homo sapiens
32 SIRT1  
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
33 HMGA1 3159
Affinity Capture-MS Homo sapiens
34 Set 56086
Affinity Capture-MS Mus musculus
35 ARID1A 8289
Co-fractionation Homo sapiens
36 BRD4 23476
Affinity Capture-MS Homo sapiens
37 CDT1  
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
38 POLR2C 5432
Affinity Capture-MS Homo sapiens
39 KLHL20  
Affinity Capture-MS Homo sapiens
40 Eif3a 13669
Affinity Capture-MS Mus musculus
41 MYCN  
Affinity Capture-MS Homo sapiens
42 NCK1 4690
Affinity Capture-MS Homo sapiens
43 KIF14 9928
Affinity Capture-MS Homo sapiens
44 KANSL1  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
45 KLF16  
Proximity Label-MS Homo sapiens
46 CHMP4C 92421
Affinity Capture-MS Homo sapiens
47 H2AFZ 3015
Affinity Capture-MS Homo sapiens
48 POLD1 5424
Affinity Capture-MS Homo sapiens
49 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
50 HIST1H2BD 3017
Cross-Linking-MS (XL-MS) Homo sapiens
51 WHSC1 7468
Proximity Label-MS Homo sapiens
52 HMGN2 3151
Affinity Capture-MS Homo sapiens
53 SUPT5H 6829
Affinity Capture-MS Homo sapiens
54 MAPRE1 22919
Affinity Capture-MS Homo sapiens
55 CBX3 11335
Proximity Label-MS Homo sapiens
56 HIST1H2AM 8336
Affinity Capture-MS Homo sapiens
57 SMARCA4 6597
Co-fractionation Homo sapiens
58 DEK 7913
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
59 Srp72  
Affinity Capture-MS Mus musculus
60 RPA2 6118
Proximity Label-MS Homo sapiens
61 ACTL6A 86
Co-fractionation Homo sapiens
62 HIST1H1E 3008
Affinity Capture-MS Homo sapiens
63 REXO4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
64 SUMO2 6613
Reconstituted Complex Homo sapiens
65 HIST1H1C 3006
Affinity Capture-MS Homo sapiens
66 TRIM66  
Affinity Capture-MS Homo sapiens
67 ACTB 60
Cross-Linking-MS (XL-MS) Homo sapiens
68 HECTD1 25831
Affinity Capture-MS Homo sapiens
69 EED  
Affinity Capture-MS Homo sapiens
70 NECAP1 25977
Affinity Capture-MS Homo sapiens
71 MYBBP1A 10514
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
72 DAXX  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
73 SMARCC2 6601
Co-fractionation Homo sapiens
74 SCARNA22  
Affinity Capture-RNA Homo sapiens
75 NUMA1 4926
Affinity Capture-MS Homo sapiens
76 HIST1H2BL 8340
Cross-Linking-MS (XL-MS) Homo sapiens
77 ZBTB2 57621
Affinity Capture-MS Homo sapiens
78 RRP1B 23076
Affinity Capture-MS Homo sapiens
79 HIST1H3A 8350
Co-localization Homo sapiens
Proximity Label-MS Homo sapiens
80 FANCD2  
Affinity Capture-MS Homo sapiens
81 RPS2 6187
Cross-Linking-MS (XL-MS) Homo sapiens
82 SMARCA5 8467
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
83 SIRT7  
Affinity Capture-MS Homo sapiens
84 MEX3A  
Affinity Capture-RNA Homo sapiens
85 RAD18  
Affinity Capture-MS Homo sapiens
86 MTNR1A  
Two-hybrid Homo sapiens
87 H1F0 3005
Affinity Capture-MS Homo sapiens
88 RPL7L1 285855
Affinity Capture-MS Homo sapiens
89 POLR2A 5430
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
90 HNRNPCL2 440563
Affinity Capture-MS Homo sapiens
91 SEMG1 6406
Affinity Capture-MS Homo sapiens
92 Hsph1 15505
Affinity Capture-MS Mus musculus
93 RPA3 6119
Proximity Label-MS Homo sapiens
94 APOOL 139322
Affinity Capture-MS Homo sapiens
95 DNAJC9 23234
Proximity Label-MS Homo sapiens
96 TOP1 7150
Affinity Capture-MS Homo sapiens
97 ETV3  
Proximity Label-MS Homo sapiens
98 EEF1B2 1933
Cross-Linking-MS (XL-MS) Homo sapiens
99 BAZ1A 11177
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
100 PARP1 142
Affinity Capture-MS Homo sapiens
101 RNF2  
Affinity Capture-MS Homo sapiens
102 BMI1  
Affinity Capture-MS Homo sapiens
103 ZC3HAV1 56829
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
104 HSPD1 3329
Cross-Linking-MS (XL-MS) Homo sapiens
105 LMNA 4000
Proximity Label-MS Homo sapiens
106 BRD3 8019
Affinity Capture-MS Homo sapiens
107 PYHIN1  
Affinity Capture-MS Homo sapiens
108 CCDC8  
Affinity Capture-MS Homo sapiens
109 H2AFX 3014
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
110 Cbx1  
Affinity Capture-MS Mus musculus
111 MYO1C 4641
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
112 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
113 KAT8  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
114 HDGF 3068
Affinity Capture-MS Homo sapiens
115 NR4A2  
Reconstituted Complex Homo sapiens
116 MBD3 53615
Co-fractionation Homo sapiens
117 EIF1AX 1964
Cross-Linking-MS (XL-MS) Homo sapiens
118 SMARCC1 6599
Co-fractionation Homo sapiens
119 CDK12 51755
Affinity Capture-MS Homo sapiens
120 MEN1 4221
Affinity Capture-MS Homo sapiens
121 HNRNPA2B1 3181
Cross-Linking-MS (XL-MS) Homo sapiens
122 HMGN5 79366
Affinity Capture-MS Homo sapiens
123 UTP23  
Affinity Capture-MS Homo sapiens
124 CHD4 1108
Affinity Capture-MS Homo sapiens
125 DDX58 23586
Affinity Capture-RNA Homo sapiens
126 PCNA 5111
Reconstituted Complex Homo sapiens
127 KRR1 11103
Affinity Capture-MS Homo sapiens
128 ERCC6  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
129 SUPT6H 6830
Affinity Capture-MS Homo sapiens
130 XRCC6 2547
Proximity Label-MS Homo sapiens
131 CUL7 9820
Affinity Capture-MS Homo sapiens
132 HNRNPU 3192
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
133 RSF1  
Affinity Capture-MS Homo sapiens
134 NUCKS1 64710
Affinity Capture-MS Homo sapiens
135 TFAM 7019
Affinity Capture-MS Homo sapiens
136 EXOSC1 51013
Affinity Capture-MS Homo sapiens
137 REPIN1  
Affinity Capture-MS Homo sapiens
138 RHD  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
139 EP300 2033
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here