Gene description for BAZ1B
Gene name bromodomain adjacent to zinc finger domain, 1B
Gene symbol BAZ1B
Other names/aliases WBSCR10
WBSCR9
WSTF
Species Homo sapiens
 Database cross references - BAZ1B
ExoCarta ExoCarta_9031
Vesiclepedia VP_9031
Entrez Gene 9031
HGNC 961
MIM 605681
UniProt Q9UIG0  
 BAZ1B identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Urine 19056867    
 Gene ontology annotations for BAZ1B
Molecular Function
    ATP binding GO:0005524 IEA
    chromatin binding GO:0003682 IDA
    vitamin D receptor activator activity GO:0071884 IEA
    lysine-acetylated histone binding GO:0070577 IDA
    zinc ion binding GO:0008270 NAS
    protein binding GO:0005515 IPI
    non-membrane spanning protein tyrosine kinase activity GO:0004715 IEA
    histone kinase activity GO:0035173 IDA
    protein tyrosine kinase activity GO:0004713 IDA
Biological Process
    chromatin assembly or disassembly GO:0006333 IEA
    heart morphogenesis GO:0003007 ISS
    peptidyl-tyrosine phosphorylation GO:0018108 IEA
    transcription, DNA-templated GO:0006351 NAS
    histone phosphorylation GO:0016572 IDA
    regulation of transcription, DNA-templated GO:0006355 ISS
    positive regulation of receptor activity GO:2000273 IEA
    chromatin-mediated maintenance of transcription GO:0048096 ISS
    double-strand break repair GO:0006302 ISS
    cellular response to DNA damage stimulus GO:0006974 IDA
Subcellular Localization
    condensed chromosome GO:0000793 IEA
    nuclear replication fork GO:0043596 IDA
    pericentric heterochromatin GO:0005721 IEA
 Experiment description of studies that identified BAZ1B in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
EV Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
EV Enriched markers
✔
Canx
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
EV Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
EV Enriched markers
✔
Canx
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
EV Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
EV Enriched markers
✔
Canx
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
EV Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
EV Enriched markers
✔
Canx
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 63
MISEV standards
✘ EV Biophysical techniques
✔
AQP2
EV Enriched markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for BAZ1B
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 BAZ1A 11177
Co-fractionation Homo sapiens
2 CHAF1B  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
3 ARID1A 8289
Affinity Capture-MS Homo sapiens
4 ACTL6A 86
Affinity Capture-MS Homo sapiens
5 SUPT16H 11198
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
6 VDR  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
7 SMARCE1 6605
Affinity Capture-MS Homo sapiens
8 SMARCB1 6598
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
9 TOP2B 7155
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
10 TRG1  
Affinity Capture-MS Homo sapiens
11 ESR1  
Affinity Capture-Western Homo sapiens
12 SMARCC1 6599
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
13 SMARCD1 6602
Affinity Capture-MS Homo sapiens
14 SMARCA5 8467
Affinity Capture-Western Homo sapiens
15 SMARCC2 6601
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
View the network image/svg+xml
 Pathways in which BAZ1B is involved
No pathways found





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